| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yan Wang, Slim Fellah, Martin Reis, Kristin P Guilliams, Melanie E Fields, Karen Steger-May, Amy E Mirro, Josiah B Lewis, Chunwei Ying, Rachel A Cohen, Monica L Hulbert, Allison A King, Yasheng Chen, Jin-Moo Lee, Hongyu An, Andria L For. Cerebral Oxygen Metabolic Stress in Children and Adults With Large Vessel Vasculopathy Due to Sickle Cell Disease. Neurology. vol 103. issue 11. 2024-11-16. PMID:39546738. |
large vessel vasculopathy (lvv), or moyamoya syndrome, increases the risk of stroke in patients with sickle cell disease (scd), yet effective treatments are lacking. |
2024-11-16 |
2024-11-18 |
Not clear |
| Alexander K Song, Wesley Thomas Richerson, Megan Aumann, Spencer L Waddle, Randall Sky Jones, Samantha M Davis, Lauren Milner, Chelsea Lee, Larry Taylor Davis, Sumit Pruthi, Dann Martin, Lori C Jordan, Manus Joseph Donahu. Cerebral vascular shunting and oxygen metabolism in sickle cell disease. Blood advances. 2024-11-15. PMID:39546745. |
patients with sickle cell disease (scd) are at elevated risk of silent cerebral infarcts and strokes; however, they frequently lack established stroke risk factors (e.g., macrovascular arterial steno-occlusion) and as such the mechanisms underlying such events are incompletely characterized. |
2024-11-15 |
2024-11-18 |
human |
| Jennifer M Jones, Julia Wool, Elizabeth P Crowe, Evan M Bloch, Lydia H Pecker, Sophie Lanzkro. Longitudinal outcomes of chronically transfused adults with sickle cell disease and a history of childhood stroke. Transfusion. 2024-11-06. PMID:39501512. |
many children with sickle cell disease (scd) who suffer a stroke receive chronic transfusion therapy (ctt) indefinitely; however, their adulthood neurologic outcomes have not been reported. |
2024-11-06 |
2024-11-08 |
Not clear |
| Akram M Asbeutah, Saad A Asbeutah, Akmal Zahra, Abdullah A AlMajran, Adekunle Adekil. Longitudinal assessment of transcranial Doppler imaging in children with sickle cell disease without neurological symptoms. BMC pediatrics. vol 24. issue 1. 2024-10-29. PMID:39468500. |
stroke is one of the most devastating complications of sickle cell disease (scd). |
2024-10-29 |
2024-10-31 |
Not clear |
| Maksymilian Baryła, Michał Skrzycki, Roman Danielewicz, Maciej Kosieradzki, Marta Strug. Protein biomarkers in assessing kidney quality before transplantation‑current status and future perspectives (Review). International journal of molecular medicine. vol 54. issue 6. 2024-10-07. PMID:39370783. |
to meet the demand for kidney transplants (ktx), organs are frequently retrieved not only from standard criteria donors (scd; a donor who is aged <50 years and suffered brain death from any number of causes, such as traumatic injuries or a stroke) but also from expanded criteria donors (any donor aged >60 years or donors aged >50 years with two of the following: a history of high blood pressure, a creatinine serum level ≥1.5 mg/dl or death resulting from a stroke). |
2024-10-07 |
2024-10-09 |
Not clear |
| Fred Stephen Sarfo, Vivian Paintsil, Isaac Nyanor, Emmanuel Kofi Asafo-Adjei, Eunice Agyemang Ahmed, Samuel Blay Nguah, Evans Xorse Amuzu, Suraj Yawnumah Abubakar, Lawrence Osei Tutu, Yaa Gyamfuah Oppong Mensah, Aaron Kwasi Nartey, Agnes Asare Bediako, Leslie Osei, Abigail Adjei Mantey, Evelyn Acheampong, Daniel Ansong, Alex Osei Akot. A contemporary evaluation of the frequency & factors associated with overt stroke across the lifespan: A Ghanaian sickle cell disease registry analysis. Journal of the neurological sciences. vol 466. 2024-10-05. PMID:39368214. |
stroke is a devastating complication of sickle cell disease (scd) with significant mortality and substantial morbidity. |
2024-10-05 |
2024-10-08 |
Not clear |
| Fred Stephen Sarfo, Vivian Paintsil, Isaac Nyanor, Emmanuel Kofi Asafo-Adjei, Eunice Agyemang Ahmed, Samuel Blay Nguah, Evans Xorse Amuzu, Suraj Yawnumah Abubakar, Lawrence Osei Tutu, Yaa Gyamfuah Oppong Mensah, Aaron Kwasi Nartey, Agnes Asare Bediako, Leslie Osei, Abigail Adjei Mantey, Evelyn Acheampong, Daniel Ansong, Alex Osei Akot. A contemporary evaluation of the frequency & factors associated with overt stroke across the lifespan: A Ghanaian sickle cell disease registry analysis. Journal of the neurological sciences. vol 466. 2024-10-05. PMID:39368214. |
the burden of prevalent stroke in scd is highest in sub-saharan africa and estimated at 4.2 % to 6.4 % in the era where evidence-based prevention strategies such as use of hydroxyurea therapy and transcranial doppler ultrasound were not routine care. |
2024-10-05 |
2024-10-08 |
Not clear |
| Olubusola B Oluwole, Ann Brunson, Oyebimpe Oluyemisi Adesina, Shaina Willen, Theresa Hm Keegan, Kleber Yotsumoto Fertrin, Ted Wu. Rates of Strokes in Californians with Sickle Cell Disease in the Post-STOP Era. Blood. 2024-09-20. PMID:39302175. |
neurovascular complications, including strokes and transient ischemic attacks (tias), are common and cause significant morbidity in individuals with sickle cell disease (scd). |
2024-09-20 |
2024-09-22 |
Not clear |
| Olubusola B Oluwole, Ann Brunson, Oyebimpe Oluyemisi Adesina, Shaina Willen, Theresa Hm Keegan, Kleber Yotsumoto Fertrin, Ted Wu. Rates of Strokes in Californians with Sickle Cell Disease in the Post-STOP Era. Blood. 2024-09-20. PMID:39302175. |
the stop trial (1998) established chronic transfusions as the standard of care for children with scd at high risk for stroke. |
2024-09-20 |
2024-09-22 |
Not clear |
| Olubusola B Oluwole, Ann Brunson, Oyebimpe Oluyemisi Adesina, Shaina Willen, Theresa Hm Keegan, Kleber Yotsumoto Fertrin, Ted Wu. Rates of Strokes in Californians with Sickle Cell Disease in the Post-STOP Era. Blood. 2024-09-20. PMID:39302175. |
using statewide emergency department and hospitalization data from the california department of health care access and innovation (1991-2019), we determined the cumulative incidence and rates for primary and recurrent strokes and tias in people with scd pre- and post-stop. |
2024-09-20 |
2024-09-22 |
Not clear |
| Olubusola B Oluwole, Ann Brunson, Oyebimpe Oluyemisi Adesina, Shaina Willen, Theresa Hm Keegan, Kleber Yotsumoto Fertrin, Ted Wu. Rates of Strokes in Californians with Sickle Cell Disease in the Post-STOP Era. Blood. 2024-09-20. PMID:39302175. |
these findings underscore the need for prevention of strokes in adults with scd and suggest an emphasis on the management of modifiable cerebrovascular risk factors that have been demonstrated to be effective in the general population. |
2024-09-20 |
2024-09-22 |
Not clear |
| Jintao Wang, Paul Silaghi, Chiao Guo, David Harro, Daniel T Eitzma. Inhibition of sodium-glucose cotransporter-2 improves anaemia in mice and humans with sickle cell disease, and reduces infarct size in a murine stroke model. Journal of cellular and molecular medicine. vol 28. issue 17. 2024-09-13. PMID:39267208. |
a murine model of scd was studied to determine the effects of the sglt-2 inhibitor, empagliflozin, on anaemia and stroke size. |
2024-09-13 |
2024-09-15 |
mouse |
| Jintao Wang, Paul Silaghi, Chiao Guo, David Harro, Daniel T Eitzma. Inhibition of sodium-glucose cotransporter-2 improves anaemia in mice and humans with sickle cell disease, and reduces infarct size in a murine stroke model. Journal of cellular and molecular medicine. vol 28. issue 17. 2024-09-13. PMID:39267208. |
empagliflozin treatment is also associated with reduced stroke size in scd mice suggesting sglt-2 inhibitor treatment may be beneficial with regard to both anaemia and vascular complications in scd patients. |
2024-09-13 |
2024-09-15 |
mouse |
| Despina Messimeris, Hugo Bismuth, Corentin Provost, Clémentine Emaer, Nicolas Mélé, Robert Kitenge, Jean-Benoit Arlet, Laure Joseph, Brigitte Ranque, Pablo Bartolucci, Pauline Narme, David Calve. Determinants of cognitive dysfunction in adults with sickle cell-related stroke or suspected neurological morbidity. Blood advances. vol 8. issue 15. 2024-07-29. PMID:38815229. |
cognitive dysfunction appears to be a hallmark sign of scd, particularly for adults with sickle cell-related stroke or suspected neurological morbidity. |
2024-07-29 |
2024-08-02 |
Not clear |
| Adam P Robert, Ricardo A Hanel, P David Adelson, Shih-Shan Lang, Paul Grabb, Stephanie Greene, James M Johnston, Jeffrey Leonard, Suresh N Magge, Neena I Marupudi, Joseph Piatt, Rafael De Oliveira Sillero, Edward R Smith, Jodi Smith, Jennifer M Strahle, Sudhakar Vadivelu, John C Wellons, David Wrubel, Asmaa Hatem, Ciarra Moody, Sabrina H Han, Alaa Montaser, Nicklaus Millican, John M Pederson, Aleksandra S Dain, Lauren A Beslow, Philipp R Aldan. Indications for cerebral revascularization for moyamoya syndrome in pediatric sickle cell disease determined by Delphi methodology. Journal of neurosurgery. Pediatrics. 2024-07-19. PMID:39029127. |
cerebral revascularization surgery (crs) has been used to prevent stroke in children with sickle cell disease (scd) and cerebral vasculopathy (e.g., moyamoya syndrome). |
2024-07-19 |
2024-07-22 |
Not clear |
| Abdulhafiz Zakieh, Nicolas Mercure-Corriveau, Sophie Lanzkron, Xinyi Feng, Sonja Vozniak, Elizabeth P Crowe, Herleen Rai, Courtney Lawrence, Denise Bekkouri, Ruchika Goel, Aaron A R Tobian, Evan M Bloc. Chronic automated red cell exchange therapy for sickle cell disease. Transfusion. 2024-07-14. PMID:39003570. |
the data to support chronic automated red cell exchange (rce) in sickle cell disease (scd) outside of stroke prevention, is limited, especially in adults. |
2024-07-14 |
2024-07-16 |
Not clear |
| Paul Muteb Boma, Suzanne Kamin Kisula Ngoy, Jules Mulefu Panda, Bruno Bonnechèr. Empowering sickle cell disease care: the rise of Frontiers in rehabilitation sciences. vol 5. 2024-07-12. PMID:38994332. |
this perspective argues for the rapid creation of specific, cost-effective, technology-supported rehabilitation centres to advance scd care, identify patients at high risk of stroke and implement tailored rehabilitation strategies. |
2024-07-12 |
2024-07-14 |
Not clear |
| Voi Vincenzo, Gutierrez-Valle Victoria, Daniela Cuzzubbo, McMahon Corrina, Maddalena Casale, Maria Del Mar Mañú Pereira, D'Agnolo Mirco, Baba P D Inusa, Mariane de Montalembert, Raffaella Colombatt. Limited access to transcranial Doppler screening and stroke prevention for children with sickle cell disease in Europe: Results of a multinational EuroBloodNet survey. Pediatric blood & cancer. 2024-07-10. PMID:38984411. |
stroke is one of the most devastating complications for children with sickle cell disease (scd). |
2024-07-10 |
2024-07-12 |
Not clear |
| Elizabeth Ormondroyd, Christopher Grace, Wendy Borsari, Anuj Goel, Barbara McDonough, Joel Rose, Christine Seidman, Hugh Watkin. Genetic therapies for cardiomyopathy: survey of attitudes of the patient community for the CureHeart project. European journal of human genetics : EJHG. 2024-07-07. PMID:38972962. |
expressivity is variable and while sometimes mild, complications can result in sudden cardiac death (scd) at any age, heart failure and stroke. |
2024-07-07 |
2024-07-11 |
Not clear |
| Morohuntodun O Oni, Miguel Brito, Chloe Rotman, Natasha M Arche. Genetic Modifiers of Stroke in Patients with Sickle Cell Disease-A Scoping Review. International journal of molecular sciences. vol 25. issue 12. 2024-06-27. PMID:38928024. |
understanding why and in whom stroke is most likely to occur is critical to the effective prevention and treatment of individuals with scd. |
2024-06-27 |
2024-06-29 |
Not clear |