| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yuxia Lin, Changbai Huang, Huixin Gao, Xiaobo Li, Quanshi Lin, Shili Zhou, Zhiting Huo, Yanxia Huang, Chao Liu, Ping Zhan. AMBRA1 promotes apoptosis induced by dsRNA and virus through interacting with and stabilizing MAVS. Journal of cell science. 2021-12-03. PMID:34859815. |
consistently, ambra1 upregulated the apoptosis induced by semliki forest virus infection. |
2021-12-03 |
2023-08-13 |
Not clear |
| Yuxia Lin, Changbai Huang, Huixin Gao, Xiaobo Li, Quanshi Lin, Shili Zhou, Zhiting Huo, Yanxia Huang, Chao Liu, Ping Zhan. AMBRA1 promotes apoptosis induced by dsRNA and virus through interacting with and stabilizing MAVS. Journal of cell science. 2021-12-03. PMID:34859815. |
taken together, our work illustrated a role of ambra1 in the virus-induced apoptosis through interacting with and stabilizing mavs. |
2021-12-03 |
2023-08-13 |
Not clear |
| Manuela Antonioli, Benedetta Pagni, Tiziana Vescovo, Rob Ellis, Benjamin Cosway, Francesca Rollo, Veronica Bordoni, Chiara Agrati, Marie Labus, Renato Covello, Maria Benevolo, Giuseppe Ippolito, Max Robinson, Mauro Piacentini, Penny Lovat, Gian Maria Fimi. HPV sensitizes OPSCC cells to cisplatin-induced apoptosis by inhibiting autophagy through E7-mediated degradation of AMBRA1. Autophagy. vol 17. issue 10. 2021-11-16. PMID:33172332. |
hpv sensitizes opscc cells to cisplatin-induced apoptosis by inhibiting autophagy through e7-mediated degradation of ambra1. |
2021-11-16 |
2023-08-13 |
human |
| Onur Tokgun, Pervin Elvan Tokgun, Samet Turel, Behcet Inal, Kubilay Inci, Secil Tan, Ozge Can Alvu. Nutrition and cancer. vol 73. issue 9. 2021-09-08. PMID:34024207. |
therefore, possible molecular mechanisms underlying morphological changes such as autophagy (lc-3b, beclin, ambra1) and apoptosis (bcl-2) were evaluated on mrna and protein levels. |
2021-09-08 |
2023-08-13 |
Not clear |
| Luca Di Leo, Daniela De Zi. AMBRA1 has an impact on melanoma development beyond autophagy. Autophagy. vol 17. issue 7. 2021-08-18. PMID:34156327. |
ambra1 (autophagy/beclin 1 regulator 1) is a multifunctional scaffold protein involved in several cellular processes spanning from cell proliferation to apoptosis and to regulation of macroautophagy/autophagy. |
2021-08-18 |
2023-08-13 |
Not clear |
| Lin Zhao, Liting Cheng, Yongquan W. Ambra1 Alleviates Hypoxia/Reoxygenation Injury in H9C2 Cells by Regulating Autophagy and Reactive Oxygen Species. BioMed research international. vol 2020. 2021-05-10. PMID:33083461. |
ambra1 overexpression increased autophagy in the h9c2 cells, as the lc3b ii/i ratio increased, and alleviated cellular necrosis and apoptosis during hypoxia and reoxygenation. |
2021-05-10 |
2023-08-13 |
Not clear |
| Wei-Liang Su. Ambra1 in autophagy and apoptosis: Implications for cell survival and chemotherapy resistance. Oncology letters. vol 12. issue 1. 2020-09-30. PMID:27347152. |
ambra1 in autophagy and apoptosis: implications for cell survival and chemotherapy resistance. |
2020-09-30 |
2023-08-13 |
Not clear |
| Wei-Liang Su. Ambra1 in autophagy and apoptosis: Implications for cell survival and chemotherapy resistance. Oncology letters. vol 12. issue 1. 2020-09-30. PMID:27347152. |
activating molecule in beclin 1-regulated autophagy protein 1 (ambra1) is an important factor at the crossroad between autophagy and apoptosis. |
2020-09-30 |
2023-08-13 |
Not clear |
| Wei-Liang Su. Ambra1 in autophagy and apoptosis: Implications for cell survival and chemotherapy resistance. Oncology letters. vol 12. issue 1. 2020-09-30. PMID:27347152. |
the expression level and intracellular distributions of ambra1 may control the balance and conversion between autophagy and apoptosis, and modify the effectiveness of chemotherapy. |
2020-09-30 |
2023-08-13 |
Not clear |
| Wei-Liang Su. Ambra1 in autophagy and apoptosis: Implications for cell survival and chemotherapy resistance. Oncology letters. vol 12. issue 1. 2020-09-30. PMID:27347152. |
the present review focuses on the role of ambra1 in autophagy and apoptosis and assesses the implications for cell survival and chemotherapy resistance. |
2020-09-30 |
2023-08-13 |
Not clear |
| Jie Liu, Zhiyuan Chen, Jia Guo, Lei Wang, Xiuheng Li. Ambra1 induces autophagy and desensitizes human prostate cancer cells to cisplatin. Bioscience reports. vol 39. issue 8. 2020-09-14. PMID:29101240. |
we explored the regulation by the ambra1 manipulation on the induction of apoptosis and autophagy in human pca du145 cells in the presence of cisplatin, via up- or down-regulating ambra1 expression. |
2020-09-14 |
2023-08-13 |
human |
| Jie Liu, Zhiyuan Chen, Jia Guo, Lei Wang, Xiuheng Li. Ambra1 induces autophagy and desensitizes human prostate cancer cells to cisplatin. Bioscience reports. vol 39. issue 8. 2020-09-14. PMID:29101240. |
our results demonstrated that the ambra1 up-regulation reduced, whereas ambra1 knockdown increased the cisplatin-induced apoptosis, caspase 3 cleavage, and poly adp-ribose polymerase (parp) cleavage. |
2020-09-14 |
2023-08-13 |
human |
| Jie Liu, Zhiyuan Chen, Jia Guo, Lei Wang, Xiuheng Li. Ambra1 induces autophagy and desensitizes human prostate cancer cells to cisplatin. Bioscience reports. vol 39. issue 8. 2020-09-14. PMID:29101240. |
in conclusion, ambra1 negatively regulates the cisplatin-induced apoptosis and the cisplatin-mediated growth reduction in du145 cells, in association with the ambra1-mediated autophagy promotion. |
2020-09-14 |
2023-08-13 |
human |
| Bojie Yang, Quansheng Liu, Yuanhong B. Autophagy and apoptosis are regulated by stress on Bcl2 by AMBRA1 in the endoplasmic reticulum and mitochondria. Theoretical biology & medical modelling. vol 16. issue 1. 2020-07-23. PMID:31665034. |
autophagy and apoptosis are regulated by stress on bcl2 by ambra1 in the endoplasmic reticulum and mitochondria. |
2020-07-23 |
2023-08-13 |
Not clear |
| Bojie Yang, Quansheng Liu, Yuanhong B. Autophagy and apoptosis are regulated by stress on Bcl2 by AMBRA1 in the endoplasmic reticulum and mitochondria. Theoretical biology & medical modelling. vol 16. issue 1. 2020-07-23. PMID:31665034. |
b-cell lymphoma-2 family proteins sense different stresses and interact with ambra1 to regulate autophagy and apoptosis, which are respectively mediated by beclin1 and caspases. |
2020-07-23 |
2023-08-13 |
Not clear |
| Bojie Yang, Quansheng Liu, Yuanhong B. Autophagy and apoptosis are regulated by stress on Bcl2 by AMBRA1 in the endoplasmic reticulum and mitochondria. Theoretical biology & medical modelling. vol 16. issue 1. 2020-07-23. PMID:31665034. |
therefore, we investigated how different levels of stress on b-cell lymphoma-2 family proteins that bind to ambra1 in the endoplasmic reticulum and mitochondria regulate the switch from autophagy to apoptosis. |
2020-07-23 |
2023-08-13 |
Not clear |
| Livia La Barbera, Francescangelo Vedele, Annalisa Nobili, Marcello D'Amelio, Paraskevi Krashi. Neurodevelopmental Disorders: Functional Role of Ambra1 in Autism and Schizophrenia. Molecular neurobiology. vol 56. issue 10. 2020-01-30. PMID:30915711. |
additional studies have revealed that ambra1 is able to coordinate cell responses to stress conditions such as starvation, and it actively participates in cell proliferation, cytoskeletal modification, apoptosis, mitochondria removal, and cell cycle downregulation. |
2020-01-30 |
2023-08-13 |
Not clear |
| W L Sun, L Wang, J Luo, H W Zhu, Z W Ca. Ambra1 inhibits paclitaxel-induced apoptosis in breast cancer cells by modulating the Bim/mitochondrial pathway. Neoplasma. vol 66. issue 3. 2019-09-09. PMID:30784282. |
ambra1 inhibits paclitaxel-induced apoptosis in breast cancer cells by modulating the bim/mitochondrial pathway. |
2019-09-09 |
2023-08-13 |
Not clear |
| W L Sun, L Wang, J Luo, H W Zhu, Z W Ca. Ambra1 inhibits paclitaxel-induced apoptosis in breast cancer cells by modulating the Bim/mitochondrial pathway. Neoplasma. vol 66. issue 3. 2019-09-09. PMID:30784282. |
however, the mechanism by which ambra1 regulates apoptosis has not been fully clarified. |
2019-09-09 |
2023-08-13 |
Not clear |
| W L Sun, L Wang, J Luo, H W Zhu, Z W Ca. Ambra1 inhibits paclitaxel-induced apoptosis in breast cancer cells by modulating the Bim/mitochondrial pathway. Neoplasma. vol 66. issue 3. 2019-09-09. PMID:30784282. |
moreover, whether ambra1 participates in the regulation of paclitaxel-induced apoptosis in breast cancer cells is not clear. |
2019-09-09 |
2023-08-13 |
Not clear |