Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Bao-Wen Zhang, Ying Li, Xian-Juan Ko. [Resistance exercise regulates hippocampal microglia polarization through TREM2/NF-κB/STAT3 signal pathway to improve cognitive dysfunction in T2DM mice]. Sheng li xue bao : [Acta physiologica Sinica]. vol 76. issue 5. 2024-10-29. PMID:39468808. |
the results showed that the spatial learning and memory of the db/db group were significantly declined, the neurons in the hippocampus were damaged, the protein levels of psd93, psd95, bdnf, cd206, arg1, trem2 and the ratio of p-creb/creb were significantly down-regulated, the mrna and protein expression levels of il-6, il-1β and tnf-α were significantly up-regulated, and the protein levels of inos, iba-1, nf-κb and the ratio of p-stat3/stat3 were significantly increased compared with the con group. |
2024-10-29 |
2024-10-31 |
mouse |
Jori L Waner, Hanna K Hausman, Jessica N Kraft, Cheshire Hardcastle, Nicole D Evangelista, Andrew O'Shea, Alejandro Albizu, Emanuel M Boutzoukas, Emily J Van Etten, Pradyumna K Bharadwaj, Hyun Song, Samantha G Smith, Steven T DeKosky, Georg A Hishaw, Samuel S Wu, Michael Marsiske, Ronald Cohen, Gene E Alexander, Eric C Porges, Adam J Wood. Connecting memory and functional brain networks in older adults: a resting-state fMRI study. GeroScience. 2023-10-09. PMID:37814198. |
con may make small but unique contributions to learning and memory across domains, making it a valuable target in future longitudinal studies and interventions to attenuate memory decline. |
2023-10-09 |
2023-10-15 |
human |
Jori L Waner, Hanna K Hausman, Jessica N Kraft, Cheshire Hardcastle, Nicole D Evangelista, Andrew O'Shea, Alejandro Albizu, Emanuel M Boutzoukas, Emily J Van Etten, Pradyumna K Bharadwaj, Hyun Song, Samantha G Smith, Steven T DeKosky, Georg A Hishaw, Samuel S Wu, Michael Marsiske, Ronald Cohen, Gene E Alexander, Eric C Porges, Adam J Wood. Connecting memory and functional brain networks in older adults: a resting-state fMRI study. GeroScience. 2023-10-09. PMID:37814198. |
this study examined within-network connectivity of cingulo-opercular (con), frontoparietal control (fpcn), and default mode (dmn) networks, and verbal and visuospatial learning and memory in older adults. |
2023-10-09 |
2023-10-15 |
human |
Xiankun Zhu, Pei Wang, Haijun Liu, Jing Zhan, Jin Wang, Mi Li, Ling Zeng, Ping X. Changes and Significance of SYP and GAP-43 Expression in the Hippocampus of CIH Rats. International journal of medical sciences. vol 16. issue 3. 2019-07-24. PMID:30911273. |
in this study, 25 adult male sprague dawley (sd) rats were randomly divided into a normal control group (con) and a chronic intermittent hypoxia group (cih) with four time points as follows: 1 w, 2 w, 3 w, and 4 w. the behavioural changes (primarily learning and memory abilities) were observed by the morris water maze in each group, consisting of 5 rats per group.the localization of syp and gap-43 in hippocampal ca1 neurons was observed, and the expression of syp and gap-43 in the hippocampus was detected by western blotting. |
2019-07-24 |
2023-08-13 |
rat |
Timothy C Durazzo, Linda Abadjian, Adam Kincaid, Tobias Bilovsky-Muniz, Lauren Boreta, Grant E Gauge. The influence of chronic cigarette smoking on neurocognitive recovery after mild traumatic brain injury. Journal of neurotrauma. vol 30. issue 11. 2014-01-23. PMID:23421788. |
at ap1, nsmtbi and smtbi were inferior to con on measures of auditory-verbal learning and memory; nsmtbi performed more poorly than con on processing speed and global neurocognition, and smtbi performed worse than con on working memory measures; nsmtbi were inferior to smtbi on visuospatial memory. |
2014-01-23 |
2023-08-12 |
human |