Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Bao-Wen Zhang, Ying Li, Xian-Juan Ko. [Resistance exercise regulates hippocampal microglia polarization through TREM2/NF-κB/STAT3 signal pathway to improve cognitive dysfunction in T2DM mice]. Sheng li xue bao : [Acta physiologica Sinica]. vol 76. issue 5. 2024-10-29. PMID:39468808. |
the results showed that the spatial learning and memory of the db/db group were significantly declined, the neurons in the hippocampus were damaged, the protein levels of psd93, psd95, bdnf, cd206, arg1, trem2 and the ratio of p-creb/creb were significantly down-regulated, the mrna and protein expression levels of il-6, il-1β and tnf-α were significantly up-regulated, and the protein levels of inos, iba-1, nf-κb and the ratio of p-stat3/stat3 were significantly increased compared with the con group. |
2024-10-29 |
2024-10-31 |
mouse |
Camila Berbert-Gomes, Júlia S Ramos, João G Silveira-Rodrigues, Daniel M M Leite, Bruno P Melo, Danusa D Soare. An acute bout of resistance exercise increases BDNF in hippocampus and restores the long-term memory of insulin-resistant rats. Experimental brain research. 2024-03-07. PMID:38453752. |
insulin-resistant rats had 20% worse long-term memory (ltm) (p < 0.01) and lower bdnf concentration in the hippocampus (-14.6%; p < 0.05) when compared to non-insulin-resistant rats (con). |
2024-03-07 |
2024-03-10 |
rat |
Xianqiang Zhang, Haonan Li, Haoran Sun, Yinghong Jiang, Aihong Wang, Yujia Kong, Xiue Sun, Guohui Zhu, Qi Li, Zhongde Du, Hongwei Sun, Lin Su. Effects of BDNF Signaling on Anxiety-Related Behavior and Spatial Memory of Adolescent Rats in Different Length of Maternal Separation. Frontiers in psychiatry. vol 11. 2020-09-28. PMID:32793001. |
bdnf protein levels in the pfc were lower in pms compared to eh and further reduced in con male rats. |
2020-09-28 |
2023-08-13 |
rat |
Zhe Ying, Roland R Roy, V Reggie Edgerton, Fernando Gómez-Pinill. Exercise restores levels of neurotrophins and synaptic plasticity following spinal cord injury. Experimental neurology. vol 193. issue 2. 2005-07-15. PMID:15869943. |
bdnf mrna levels on the lesioned side of the spinal cord lumbar region of sed-hx rats were approximately 80% of con values at all time points and bdnf protein levels were approximately 40% of con at 28 days. |
2005-07-15 |
2023-08-12 |
rat |
Zhe Ying, Roland R Roy, V Reggie Edgerton, Fernando Gómez-Pinill. Exercise restores levels of neurotrophins and synaptic plasticity following spinal cord injury. Experimental neurology. vol 193. issue 2. 2005-07-15. PMID:15869943. |
the levels of the downstream effectors for the action of bdnf on synaptic plasticity synapsin i and creb were lower in sed-hx than con rats at all time points. |
2005-07-15 |
2023-08-12 |
rat |