All Relations between bdnf and gfap

Publication Sentence Publish Date Extraction Date Species
Erika Yolanda Hernández Sandoval, Zulma Janeth Dueñas Góme. Irisin and neuroinflammation: Challenges and opportunities. Experimental and molecular pathology. vol 140. 2024-10-28. PMID:39467426. the review conducted found several studies describing the effect of irisin on pathways such as stat3, p38, camp/pka/creb, as well as effects on gfap protein expression or apoptosis processes in both in vitro and in vivo models; likewise, these pathways are associated with better bdnf expression. 2024-10-28 2024-10-31 Not clear
Maria V Zakharova, Anna A Kovalenko, Olga E Zubareva, Alexander P Schwarz, Tatiana Y Postnikova, Alina M Trofimova, Aleksey V Zaitse. Pentylenetetrazole-Induced Seizures Cause Short-Term Changes in the Phenotype of Microglial and Astroglial Cells in the Hippocampus and Temporal Cortex of Young Male Wistar Rats. Journal of neuroscience research. vol 102. issue 9. 2024-09-21. PMID:39305083. an increase in the expression of the gfap, slc1a2, slc1a1, il1b, tnfa, bdnf, and fgf2 genes, and the a2 astrocyte condition marker s100a10, was observed. 2024-09-21 2024-09-24 rat
Siyu Liu, Xiaoqiang Du, Ziyan Chen, Ruying Zhou, Hongqi Wang, Xin Mao, Jiahe Du, Guitao Zhang, Hui Li, Yizhi Song, Lirong Chang, Yan W. Activation of astrocytic NMDA receptors counteracted Aβ-induced reduction of BDNF and elevation of GFAP and complement 3 in the hippocampal astrocytes. Neuroscience. 2024-09-14. PMID:39276842. activation of astrocytic nmda receptors counteracted aβ-induced reduction of bdnf and elevation of gfap and complement 3 in the hippocampal astrocytes. 2024-09-14 2024-09-18 Not clear
En Zhao, Qian Yu, Meilei Wang, Zhengqiu Wang, Bin Jiang, Xiang Ma, Bin Zhou, Qingyong Dai, Jinyu Li, Shiming Wang, Fengjuan Chen, Xiaojun Yan. Value of serum brain-derived neurotrophic factor and glial fibrillary acidic protein for detecting depression in patients with Helicobacter pylori infection. Neuroscience letters. 2024-02-25. PMID:38403261. this study aimed to evaluate the value of serum brain-derived neurotrophic factor (bdnf) and glial fibrillary acidic protein (gfap) for predicting depression in h. pylori-positive patients. 2024-02-25 2024-02-28 Not clear
Xiaonan Wang, Fuping Zhang, Le Niu, Junni Yan, Huanhuan Liu, Di Wang, Juan Hui, Haiyue Dai, Jinggui Song, Zhaohui Zhan. High-frequency repetitive transcranial magnetic stimulation improves depressive-like behaviors in CUMS-induced rats by modulating astrocyte GLT-1 to reduce glutamate toxicity. Journal of affective disorders. 2023-12-30. PMID:38159655. moreover, rtms ameliorated the reduction in gfap and glt-1 expression, alleviated the decrease in bdnf, psd95 and synapsin-1 expression, also reversed the expression levels of bax and bcl2 in the hippocampus of cums-induced rats. 2023-12-30 2024-01-05 rat
Thomas Jacobus Geus, Glenn Franken, Bert Bert Jooste. Conventional, High Frequency and Differential Targeted Multiplexed Spinal Cord Stimulation in experimental Painful Diabetic Peripheral Neuropathy: pain behavior and role of the central inflammatory balance. Molecular pain. 2023-07-25. PMID:37488684. the inflammatory balance and glial response were analyzed in the dorsal spinal cord based on rna expression of pro- and anti-inflammatory cytokines (tnf-α, il-1ß, il-4, il-10), a microglia marker (itgam), an astrocyte marker (gfap), a t-cell marker (cd3d), microglia proliferation markers (irf8, adgre1) and p2x4, p13-mapk, bdnf signaling markers (p2x4, mapk14, bdnf). 2023-07-25 2023-08-14 Not clear
Xiaonan Cao, Mengxiao Fu, Qiyan Du, Zhongjie Chan. Developmental toxicity of black phosphorus quantum dots in zebrafish (Danio rerio) embryos. Chemosphere. 2023-05-27. PMID:37244547. at the molecular level, the mrna transcript levels of key genes related to skeletal development (igf1, gh, myod and lox), neurodevelopment (gfap, pomca, bdnf and mbpa), cardiovascular development (myh6, nkx2.5, myl7, tbx2b, tbx5 and gata4) and apoptosis (p53, bax, bcl-2, apaf1, caspase-3 and caspase-9) were abnormal after bpqds exposure. 2023-05-27 2023-08-14 cat
Moein Salari, Seyed Hassan Eftekhar-Vaghefi, Majid Asadi-Shekaari, Khadijeh Esmaeilpour, Somayeh Solhjou, Maryam Amiri, Meysam Ahmadi-Zeidabad. Impact of ketamine administration on chronic unpredictable stress-induced rat model of depression during extremely low-frequency electromagnetic field exposure: Behavioral, histological and molecular study. Brain and behavior. 2023-04-10. PMID:37032465. in the study, we examined the effects of ketamine and extremely low-frequency electromagnetic fields (elf-emf) on depression-like behavior, learning and memory, expression of gfap, caspase-3, p53, bdnf, and nmda receptor in animals subjected to chronic unpredictable stress (cus). 2023-04-10 2023-08-14 rat
Shaoyu Yen, Hong-Yi Wu, Yuhling Wang, Chih-Mao Huang, Changwei W Wu, Jyh-Horng Chen, Lun-De Lia. Revisiting the effects of exercise on cerebral neurovascular functions in rats using multimodal assessment techniques. iScience. vol 26. issue 4. 2023-04-10. PMID:37035001. western blot results in the exe group showed significant increases in bdnf, gfap, and neun levels and significant decreases in neurodegenerative disease markers. 2023-04-10 2023-08-14 rat
Guanlan Liu, Israr Khan, Yuxi Li, Yun Yang, Xuerui Lu, Yafei Wang, Junxiang Li, Chunjiang Zhan. Overcoming Anxiety Disorder by Probiotic Foods (Basel, Switzerland). vol 11. issue 22. 2023-03-08. PMID:36429192. lzu-j-tsl6 was able to effectively increase the gaba content in the mice hippocampus (p < 0.0001) and restore some markers related to anxiety such as brain-derived neurotrophic factor (bdnf), glial fibrillary acidic protein (gfap), and 5-hydroxytryptamine (5-ht). 2023-03-08 2023-08-16 mouse
Xiaona Zhao, Xinxin Li, Huiling Guo, Panmei Liu, Minyu Ma, Yanping Wan. Resolvin D1 Attenuates Mechanical Allodynia after Burn Injury: Involvement of Spinal Glia, p38 MAPK, and BDNF/TrkB signaling. Molecular pain. 2023-02-11. PMID:36765459. pain behavior and the expression levels of spinal dorsal horn iba-1 (microglia marker), gfap (astrocyte marker), p-p38 mitogen-activated protein kinase (mapk), brain-derived neurotrophic factor (bdnf), and tropomyosin-related kinase b (trkb) were detected by behavioral and immunocytochemical assays. 2023-02-11 2023-08-14 rat
Abdulla M A Mahmoud, Eman M Mantawy, Sara A Wahdan, Ramy M Ammar, Ebtehal El-Demerdas. Vildagliptin restores cognitive function and mitigates hippocampal neuronal apoptosis in cisplatin-induced chemo-brain: Imperative roles of AMPK/Akt/CREB/ BDNF signaling cascades. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 159. 2023-01-14. PMID:36640673. in addition, the neuroprotective mechanisms of vilda include diminishing oxidative stress by reducing mda levels while raising gsh levels and sod activity, repressing neuronal apoptosis as shown by elevated bcl-2 levels together with diminished bax and caspase-3 expressions, inhibiting neuroinflammation as shown by decreased gfap expression, and finally boosting hippocampal neurogenesis and survival by upregulating expressions of bdnf and pcna. 2023-01-14 2023-08-14 human
Arianne S Gravesteijn, Heleen Beckerman, Eline Aj Willemse, Hanneke E Hulst, Brigit A de Jong, Charlotte E Teunissen, Vincent de Groo. Brain-derived neurotrophic factor, neurofilament light and glial fibrillary acidic protein do not change in response to aerobic training in people with MS-related fatigue - a secondary analysis of a randomized controlled trial. Multiple sclerosis and related disorders. vol 70. 2023-01-09. PMID:36621163. brain-derived neurotrophic factor (bdnf), neurofilament light (nfl), and glial fibrillary acidic protein (gfap) are blood-based biomarkers for neurogenesis, axonal damage and astrocyte reactivity, respectively. 2023-01-09 2023-08-14 Not clear
Ying Zhang, Guiping Wang, Rui Li, Ruitong Liu, Zengli Yu, Zengli Zhang, Zhongxiao Wa. Trimethylamine N-oxide aggravated cognitive impairment from APP/PS1 mice and protective roles of voluntary exercise. Neurochemistry international. 2022-12-02. PMID:36460238. tmao group has significantly upregulated bace1 from both hippocampus and cortex, also increased cathepsin b, p-tau at ser396&ser404, gfap, p-nf-κb p65 in cortex, while reduced bdnf, synaptophysin and psd95 in hippocampus, also reduced occludin and zo-1 from cortex, and reduced occludin from colon. 2022-12-02 2023-08-14 mouse
Shukai Zheng, Qiong Zhang, Ruotong Wu, Xiaoling Shi, Jiajun Peng, Wei Tan, Wenlong Huang, Kusheng Wu, Caixia Li. Behavioral changes and transcriptomic effects at embryonic and post-embryonic stages reveal the toxic effects of 2,2',4,4'-tetrabromodiphenyl ether on neurodevelopment in zebrafish (Danio rerio). Ecotoxicology and environmental safety. vol 248. 2022-11-24. PMID:36423367. consistent with the locomotion and kegg results, bde-47 affected the expression of genes for central nervous system (gfap, mbpa, bdnf & pomcb), early neurogenesis (neurog1 & elavl3), and axonal development (tuba1a, tuba1b, tuba1c, syn2a, gap43 & shha). 2022-11-24 2023-08-14 zebrafish
Samuel Treviño, Alfonso Díaz, Getsemaní González-López, Jorge Guevar. Differential biochemical-inflammatory patterns in the astrocyte-neuron axis of the hippocampus and frontal cortex in Wistar rats with metabolic syndrome induced by high fat or carbohydrate diets. Journal of chemical neuroanatomy. vol 126. 2022-11-14. PMID:36374648. after 3 months, we evaluated zoometry, a serum bioclinical profile, and in the hippocampus and frontal cortex, we performed biochemical assays (concentration of lactate, glutamate, fatty acids, and asat, alat, and ldh activity), immunoreactivity tests (gfap, cox2, cd36, and bdnf), and immunoassays (tnf-α, il-1β, il-6, and pge2). 2022-11-14 2023-08-14 rat
Karema Abu-Elfotuh, Somaia A Abdel-Sattar, Ashwaq Najemaldeen Abbas, Yasmen F Mahran, Aliah R Alshanwani, Ahmed Mohsen Elsaid Hamdan, Ahmed M Atwa, Enji Reda, Yasmin M Ahmed, Sameh S Zaghlool, Mahmoud Nour El-Di. The protective effect of thymoquinone or/and thymol against monosodium glutamate-induced attention-deficit/hyperactivity disorder (ADHD)-like behavior in rats: Modulation of Nrf2/HO-1, TLR4/NF-κB/NLRP3/caspase-1 and Wnt/β-Catenin signaling pathways in rat model. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 155. 2022-10-22. PMID:36271575. all treated groups showed improvement in msg-induced aberrations in brain levels of gsh, il-1β, tnf-α, gfap, glutamate, calcium, dopamine, norepinephrine, wnt3a, β-catenin and bdnf. 2022-10-22 2023-08-14 human
Elham Akbari, Dawood Hossaini, Ghulam Yahya Amiry, Mostafa Ansari, Murtaza Haidari, Farimah Beheshti, S Mohammad Ahmadi-Soleiman. Vitamin B12 administration prevents ethanol-induced learning and memory impairment through re-establishment of the brain oxidant/antioxidant balance, enhancement of BDNF and suppression of GFAP. Behavioural brain research. 2022-10-15. PMID:36243244. vitamin b12 administration prevents ethanol-induced learning and memory impairment through re-establishment of the brain oxidant/antioxidant balance, enhancement of bdnf and suppression of gfap. 2022-10-15 2023-08-14 mouse
Zhi Jiang, Jie Wang, Gaohui Sun, Meijiang Fen. BDNF-modified human umbilical cord mesenchymal stem cells-derived dopaminergic-like neurons improve rotation behavior of Parkinson's disease rats through neuroprotection and anti-neuroinflammation. Molecular and cellular neurosciences. 2022-10-13. PMID:36228967. results showed that transplantation of bdnf-modified huc-mscs-derived daergic-like neurons improved the apomorphine induced rotation behavior of pd rats, increased the dopamine concentration and the expression of glial fibrillary acidic protein (gfap) and ionized calcium-binding adaptor molecule-1 (iba-1) in the striatum, promoted the expression of tyrosine hydroxylase (th), nuclear receptor-related factor 1 (nurr1), pituitary homeobox 3 (pitx3), bdnf, tyrosine kinase b (trkb), phosphatidylinositol-3-hydroxykinase (pi3k), phosphorylated protein kinase b (p-akt), heat shock protein 60 (hsp60), toll-like receptor 4 (tlr4) and myeloid differentiation factor 88 (myd88) and inhibited the neural apoptosis in the substantia nigra (sn) and striatum. 2022-10-13 2023-08-14 human
Chen Hong, Zhi Wang, Si-Li Zheng, Wen-Jun Hu, Shu-Na Wang, Yan Zhao, Chao-Yu Mia. Metrnl regulates cognitive dysfunction and hippocampal BDNF levels in D-galactose-induced aging mice. Acta pharmacologica Sinica. 2022-10-13. PMID:36229598. furthermore, metrnl knockout significantly reduced hippocampal bdnf, trkb, and glial fibrillary acidic protein (gfap) levels in the d-gal-induced aging mice. 2022-10-13 2023-08-14 mouse