All Relations between cort and hippocampus

Publication Sentence Publish Date Extraction Date Species
Guanhao Wang, Lining Cao, Shuanqing Li, Meihui Zhang, Yingqi Li, Jinjin Duan, You Li, Zhangsen Hu, Jiaan Wu, Jianbo Ni, Danmei Lan, Tianming Li, Jianfeng L. Gut microbiota dysbiosis-mediated ceramides elevation contributes to corticosterone-induced depression by impairing mitochondrial function. NPJ biofilms and microbiomes. vol 10. issue 1. 2024-10-29. PMID:39468065. corticosterone (cort)-treated mice showed depression-like behaviors, reduced hippocampal neurogenesis, and altered composition of the gm. 2024-10-29 2024-10-31 mouse
Guanhao Wang, Lining Cao, Shuanqing Li, Meihui Zhang, Yingqi Li, Jinjin Duan, You Li, Zhangsen Hu, Jiaan Wu, Jianbo Ni, Danmei Lan, Tianming Li, Jianfeng L. Gut microbiota dysbiosis-mediated ceramides elevation contributes to corticosterone-induced depression by impairing mitochondrial function. NPJ biofilms and microbiomes. vol 10. issue 1. 2024-10-29. PMID:39468065. our study demonstrated a link between chronic exposure to cort and its impact on gm composition, which induces ceramides accumulation, ultimately leading to hippocampal mitochondrial dysfunction. 2024-10-29 2024-10-31 mouse
Zlatina Nenchovska, Milena Atanasova, Tsveta Stoynova, Gergana Toteva, Jana Tchekalarov. Detrimental effect of prenatal progesterone exposure on anxiety and depressive-like responses in adult male and female rat offspring: role of plasma, hippocampal corticosterone and hippocampal progesterone receptors. Physiology & behavior. 2024-10-11. PMID:39393450. therefore, the present study was designed to investigate the effect of prenatal pro treatment on anxiety- and depression-like behavior and the effect on plasma, hippocampal corticosterone (cort) and hippocampal progesterone receptor (pr) in young adult male and female rat offspring. 2024-10-11 2024-10-14 rat
Zlatina Nenchovska, Milena Atanasova, Tsveta Stoynova, Gergana Toteva, Jana Tchekalarov. Detrimental effect of prenatal progesterone exposure on anxiety and depressive-like responses in adult male and female rat offspring: role of plasma, hippocampal corticosterone and hippocampal progesterone receptors. Physiology & behavior. 2024-10-11. PMID:39393450. the results indicate that prenatal pro exposure at low and high doses (10 and 50 mg/kg, s.c. during g0-g10) induces anxiogenic and depressive-like effects compared to vehicle-treated controls, which are associated with high plasma and hippocampal cort levels and upregulated hippocampal pr in male and female adult offspring. 2024-10-11 2024-10-14 rat
Shan Xing, Shuyi Xu, Linjiao Wang, Liyuan Guo, Xin Zhou, Haoxin Wu, Wei Wang, Lanying Li. Salidroside exerts antidepressant-like action by promoting adult hippocampal neurogenesis through SIRT1/PGC-1α signalling. Acta neuropsychiatrica. 2024-09-30. PMID:39344773. in addition, sal treatment reversed the reduction in the number of ki-67, brdu, and neun in the hippocampus due to cort treatment. 2024-09-30 2024-10-02 mouse
Wenli Ma, Dayun Sui, Weilun Sun, Ping Yu, Yuangeng Li, Meiqi Guo, Huifeng Wang, Xiaoze Zhang, Xiaofeng Yu, Wenwen Fu, Huali X. 5,7,3',4',5'-Pentamethoxyflavone, a Flavonoid Monomer Extracted From Murraya paniculata (L.) Jack, Alleviates Anxiety Through the A Phytotherapy research : PTR. 2024-09-11. PMID:39261011. enzyme-linked immunosorbent assay (elisa) kits were used to analyze the serum levels of corticosterone (cort), 5-hydroxytryptamine (5-ht), gamma-aminobutyric acid (gaba), and cyclic adenosine monophosphate (camp) in the hippocampus. 2024-09-11 2024-09-14 mouse
Gladys A Shaw, Amy J Wegener, Gretchen N Neig. Chronic Corticosterone Administration Alters Synaptic Mitochondrial Function within the Hippocampus of C57Bl/6NTac Mice. Physiology & behavior. 2024-08-29. PMID:39209050. here, we assess the effects of chronic exogenous cort administration on changes in behavior and mitochondrial respiration in hippocampal synaptosomes of male and female mice. 2024-08-29 2024-09-04 mouse
Gladys A Shaw, Amy J Wegener, Gretchen N Neig. Chronic Corticosterone Administration Alters Synaptic Mitochondrial Function within the Hippocampus of C57Bl/6NTac Mice. Physiology & behavior. 2024-08-29. PMID:39209050. despite only observing an effect of chronic cort on corticosterone concentrations in fecal and blood samples of males, chronic cort induced marked changes in hippocampal synaptic mitochondrial function of both sexes. 2024-08-29 2024-09-04 mouse
Anna Carolina Muniz Barreto, Julia Naomi Sakamoto Oliveira, Deborah Sucheck. Chronic sleep restriction during juvenility alters hedonic and anxiety-like behaviours in a sex-dependent fashion in adolescent Frontiers in neuroscience. vol 18. 2024-08-28. PMID:39188806. within each litter, one male and one female (pair) were not tested and provided blood and brain for determination of basal corticosterone (cort) levels and hippocampal bdnf. 2024-08-28 2024-08-30 rat
Guang-Nan Jin, Yu Wang, Yi-Ming Liu, Yu-Nan Lu, Jing-Mei Lu, Jing-He Wang, Jing-Wen Ma, Yan-Zhu Quan, Hong-Yan Gao, Yue-Xian Cui, Xiang Xu, Lian-Xun Pia. Arctiin Mitigates Neuronal Injury by Modulating the P2X7R/NLPR3 Inflammasome Signaling Pathway. Inflammation. 2024-08-17. PMID:39154088. the findings revealed that arc not only mitigates hippocampal neuropathological damage and reduces serum cort levels in cums-exposed mice but also enhances cell activity while reducing lactate dehydrogenase release in cort-stimulated pc12 cells. 2024-08-17 2024-08-20 mouse
Joanna Medina, Rose M De Guzman, Joanna L Workma. Prolactin mitigates chronic stress-induced maladaptive behaviors and physiology in ovariectomized female rats. Neuropharmacology. 2024-07-31. PMID:39084597. prolactin treatment did not alter stress-induced thigmotaxis, corticosterone (cort) concentrations, hippocampal cell activation or survival. 2024-07-31 2024-08-03 rat
Liu Tongtong, Zhang Xi, Yang Hui, Lin Xiaoyuan, Liu Jian, Zhang Xiuli, Guo Dongwei, Zhao Hongqing, Zou Manshu, Lei Chang, Long Hongping, Luo Yan, Xiang Yun, G E Jinwen, Wang Yuhong, Meng Pa. Luteolin promotes neuronogenesis in hippocampus of chronic unpredictable mild stress rats and primary hippocampus of fetal rats. Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan. vol 44. issue 4. 2024-07-27. PMID:39066527. to investigate the effects of luteolin on chronic unpredictable mild stress (cums)-induced depressive rats and corticosterone (cort)-induced depressive primary hippocampal neurons, and to elucidate the mechanism behind the action. 2024-07-27 2024-07-29 rat
Shuting Luo, Feilong Wu, Qian Fang, Yue Hu, Huihui Zhang, Shishan Yuan, Chang Yang, Yan Shi, Yixiao Lu. Antidepressant effect of teriflunomide via oligodendrocyte protection in a mouse model. Heliyon. vol 10. issue 8. 2024-04-26. PMID:38655332. the administration of cort inflicts damage upon oligodendrocytes and neurons within the hippocampus. 2024-04-26 2024-04-28 mouse
Guanhao Wang, Lining Cao, Shuanqing Li, Meihui Zhang, Yingqi Li, Jinjin Duan, You Li, Zhangsen Hu, Jiaan Wu, Tianming Li, Ming Jiang, Jianfeng L. Corticosterone Impairs Hippocampal Neurogenesis and Behaviors through Biomolecules. vol 14. issue 3. 2024-03-28. PMID:38540689. herein, rna-sequencing (rna-seq) analysis of the hippocampus following corticosterone (cort) exposure revealed the central regulatory role of the 2024-03-28 2024-03-30 Not clear
Jin-Yu Liang, Shan Gao, Jia-Mei Jiang, Pin Zhang, Wei Zou, Xiao-Qing Tang, Yi-Yun Tan. Itaconate inhibits corticosterone-induced necroptosis and neuroinflammation via up-regulating menin in HT22 cells. Journal of physiology and biochemistry. 2024-03-01. PMID:38427168. corticosterone (cort) damages hippocampal neurons as well as induces neuroinflammation. 2024-03-01 2024-03-03 Not clear
Jin-Yu Liang, Shan Gao, Jia-Mei Jiang, Pin Zhang, Wei Zou, Xiao-Qing Tang, Yi-Yun Tan. Itaconate inhibits corticosterone-induced necroptosis and neuroinflammation via up-regulating menin in HT22 cells. Journal of physiology and biochemistry. 2024-03-01. PMID:38427168. in this study, we explored whether itaconate inhibits cort-induced neuroinflammation as well as necroptosis and further investigated the mediatory role of menin in this protective effect of itaconate by using an exposure of cort to ht22 cells (a hippocampal neuronal cell line). 2024-03-01 2024-03-03 Not clear
Rong Wu, Ying Xiong, Yun Gu, Li-Yue Cao, Shu-Ying Zhang, Zhi-Xiu Song, Pu Fan, Lin Li. Traditional pediatric massage enhanced hippocampal GR, BDNF and IGF-1 expressions and exerted an anti-depressant effect in an adolescent rat model of CUMS-induced depression. Neuroscience. 2024-02-16. PMID:38364964. tpm also decreased cort level in plasma, together with enhancing expressions of gr, igf-1 and bdnf in the hippocampus. 2024-02-16 2024-02-19 rat
Kotaro Miyako, Naoto Kajitani, Yusaku Koga, Hitoshi Takizawa, Shuken Boku, Minoru Takebayash. Identification of the antidepressant effect of electroconvulsive stimulation-related genes in hippocampal astrocyte. Journal of psychiatric research. vol 170. 2024-01-09. PMID:38194849. hence, we investigated antidepressant effect of electroconvulsive stimulation (ecs), an animal model of ect, -related genes in hippocampal astrocyte with a mouse model of mdd, in which corticosterone (cort)-induced depression-like behaviors were recovered by ecs. 2024-01-09 2024-01-13 mouse
Kotaro Miyako, Naoto Kajitani, Yusaku Koga, Hitoshi Takizawa, Shuken Boku, Minoru Takebayash. Identification of the antidepressant effect of electroconvulsive stimulation-related genes in hippocampal astrocyte. Journal of psychiatric research. vol 170. 2024-01-09. PMID:38194849. finally, serum and glucocorticoid kinase-1 (sgk1), a multi-functional protein kinase, was identified as a candidate gene reciprocally regulated by cort and ecs in hippocampal astrocyte. 2024-01-09 2024-01-13 mouse
Flora D'Oliveira da Silva, Cathaline Robert, Emma Lardant, Carina Pizzano, Michael R Bruchas, Bruno P Guiard, Frédéric Chauveau, Lionel Moulédou. Targeting Nociceptin/Orphanin FQ receptor to rescue cognitive symptoms in a mouse neuroendocrine model of chronic stress. Molecular psychiatry. 2023-12-20. PMID:38123728. chronic cort induced an upregulation of the n/ofq precursor in the hippocampus. 2023-12-20 2023-12-23 mouse