| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Larissa Marcely Gomes Cassiano, Karina Barbosa de Queiroz, Thais Veronez de Andrade Martins, Ana Luiza Azevedo Maia, Milene Alvarenga Rachid, Sarah J Spencer, Roney Santos Coimbr. Neonatal overfeeding attenuates microgliosis and hippocampal damage in an infant rat model of pneumococcal meningitis. Frontiers in immunology. vol 15. 2024-10-29. PMID:39469711. |
pneumococcal meningitis (pm) triggers apoptotic neuronal and progenitor cell death in the hippocampal dentate gyrus (dg), resulting in subsequent cognitive impairment. |
2024-10-29 |
2024-10-31 |
rat |
| Thomas H Lee, Ahadullah, Brian R Christie, Kangguang Lin, Parco Ming-Fai Siu, Li Zhang, Ti-Fei Yuan, Pragya Komal, Aimin Xu, Kwok-Fai So, Suk-Yu Ya. Chronic AdipoRon Treatment Mimics the Effects of Physical Exercise on Restoring Hippocampal Neuroplasticity in Diabetic Mice. Molecular neurobiology. vol 58. issue 9. 2021-10-15. PMID:34164760. |
besides, adiporon treatment increased progenitor cell proliferation and neuronal differentiation in the hippocampal dentate gyrus (dg) of diabetic mice. |
2021-10-15 |
2023-08-13 |
mouse |
| Moritz D Brandt, Diana Krüger-Gerlach, Andreas Hermann, Anne K Meyer, Kwang-Soo Kim, Alexander Storc. Early Postnatal but Not Late Adult Neurogenesis Is Impaired in the Pitx3-Mutant Animal Model of Parkinson's Disease. Frontiers in neuroscience. vol 11. 2020-10-01. PMID:28883785. |
as dopamine plays an important role in regulating precursor cell proliferation, the loss of dopaminergic neurons in the substantia nigra (sn) in pd may be related to the reduced neurogenesis observed in the neurogenic regions of the adult brain: subventricular zone (svz) and dentate gyrus (dg). |
2020-10-01 |
2023-08-13 |
mouse |
| Hanaa Malloul, Mohammed Bennis, Sara Bonzano, Giovanna Gambarotta, Isabelle Perroteau, Silvia De Marchis, Saadia Ba-M'hame. Decreased Hippocampal Neuroplasticity and Behavioral Impairment in an Animal Model of Inhalant Abuse. Frontiers in neuroscience. vol 12. 2020-09-30. PMID:29472835. |
notably, prolonged, but not acute thinner inhalation strongly affected adult neurogenesis in the dentate gyrus (dg), reducing progenitor cell proliferation after chronic treatments and impairing the survival of newborn neurons following both chronic and subchronic treatments. |
2020-09-30 |
2023-08-13 |
mouse |
| Endan Li, Yumi Kim, Sehee Kim, Seungjoon Par. Ghrelin-induced hippocampal neurogenesis and enhancement of cognitive function are mediated independently of GH/IGF-1 axis: lessons from the spontaneous dwarf rats. Endocrine journal. vol 60. issue 9. 2014-05-05. PMID:23774069. |
to explore this possibility, we assessed the impact of ghrelin on progenitor cell proliferation and differentiation in the dentate gyrus (dg) of spontaneous dwarf rats (sdrs), a dwarf strain with a mutation of the gh gene resulting in total loss of gh. |
2014-05-05 |
2023-08-12 |
rat |
| Meige Zheng, Jing Liu, Zhigang Ruan, Sumin Tian, Yuxin Ma, Jiayong Zhu, Guoying L. Intrahippocampal injection of Aβ1-42 inhibits neurogenesis and down-regulates IFN-γ and NF-κB expression in hippocampus of adult mouse brain. Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis. vol 20. issue 1. 2013-07-25. PMID:23286786. |
moreover, a significant decrease in the number of brdu/double-cortin double-positive cells in aβ1-42-injected hippocampus was observed, suggesting that aβ1-42-injection inhibited progenitor cell proliferation and neurogenesis in subgranular zone of the dg in the adult brain. |
2013-07-25 |
2023-08-12 |
mouse |
| Rebecca D Hodge, Alfredo J Garcia, Gina E Elsen, Branden R Nelson, Kristin E Mussar, Steven L Reiner, Jan-Marino Ramirez, Robert F Hevne. Tbr2 expression in Cajal-Retzius cells and intermediate neuronal progenitors is required for morphogenesis of the dentate gyrus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 9. 2013-04-22. PMID:23447624. |
dg development involves large-scale reorganization of progenitor cell populations, ultimately leading to the establishment of the subgranular zone neurogenic niche. |
2013-04-22 |
2023-08-12 |
mouse |
| Alison Hamilton, Christian Holsche. The effect of ageing on neurogenesis and oxidative stress in the APP(swe)/PS1(deltaE9) mouse model of Alzheimer's disease. Brain research. vol 1449. 2012-08-20. PMID:22418058. |
progenitor cell proliferation in the dg of app/ps1 was lower at 3, 5 and 10months compared to controls, while oxidative stress in app/ps1 mice was increased in the cortex at 3 and 5months of age compared to controls. |
2012-08-20 |
2023-08-12 |
mouse |
| Seolhwa Kim, Beom-Su Jang, Uhee Jung, Sung-Kee J. Gamma-irradiation is more efficient at depleting hippocampal neurogenesis than D-galactose/NaNO₂. Neuroscience letters. vol 498. issue 1. 2011-11-07. PMID:21571038. |
to evaluate the suppression of hippocampal neurogenesis, we examined the numbers of the doublecortin (dcx; an immature progenitor cell marker) and ki-67 (a proliferating cell marker) expressing cells by immunohistochemistry in the dentate gyrus (dg) region of the hippocampus in each treated group in comparison with those of age-matched control and 24-month-old mice as the positive control. |
2011-11-07 |
2023-08-12 |
mouse |
| E C Bunk, H-G König, T Bernas, T Engel, D C Henshall, B P Kirby, J H M Preh. BH3-only proteins BIM and PUMA in the regulation of survival and neuronal differentiation of newly generated cells in the adult mouse hippocampus. Cell death & disease. vol 1. 2011-06-23. PMID:21364616. |
our data show that bim and puma are prominently involved in the regulation of neuronal progenitor cell survival in the adult dg, but also suggest that bim has an additional role in neuronal differentiation of adult-born neural precursor cells. |
2011-06-23 |
2023-08-12 |
mouse |
| V Hernández-Rabaza, M Llorens-Martín, C Velázquez-Sánchez, A Ferragud, A Arcusa, H G Gumus, U Gómez-Pinedo, A Pérez-Villalba, J Roselló, J L Trejo, J A Barcia, J J Canale. Inhibition of adult hippocampal neurogenesis disrupts contextual learning but spares spatial working memory, long-term conditional rule retention and spatial reversal. Neuroscience. vol 159. issue 1. 2009-06-25. PMID:19138728. |
ultrastructural examination of the dg region revealed disruption of progenitor cell niches several weeks after the radiation. |
2009-06-25 |
2023-08-12 |
rat |
| Joong-Sun Kim, Jisun Jung, Hae-June Lee, Jong Choon Kim, Hongbing Wang, Sung-Ho Kim, Taekyun Shin, Changjong Moo. Differences in immunoreactivities of Ki-67 and doublecortin in the adult hippocampus in three strains of mice. Acta histochemica. vol 111. issue 2. 2009-05-13. PMID:18649926. |
we examined the differences in ki-67 (a proliferating cell marker) and doublecortin (dcx; an immature progenitor cell marker) immunolabelling in the dentate gyrus (dg) of the adult hippocampus in three strains of mice (icr, c57bl/6, and balb/c) to evaluate the effect of genetic background on adult hippocampal neurogenesis. |
2009-05-13 |
2023-08-12 |
mouse |
| Qiong Liu, Jin Yu, Wen-Li Mi, Qi-Liang Mao-Ying, Ru Yang, Yan-Qing Wang, Gen-Cheng W. Electroacupuncture attenuates the decrease of hippocampal progenitor cell proliferation in the adult rats exposed to chronic unpredictable stress. Life sciences. vol 81. issue 21-22. 2008-01-09. PMID:17976657. |
the present study was designed to investigate whether electroacupuncture (ea) was beneficial to extenuate the behavioral deficit in a rat model of depression induced by chronic unpredictable stress (cus) and to observe the effect of ea on progenitor cell proliferation in the dentate gyrus (dg) of hippocampus. |
2008-01-09 |
2023-08-12 |
rat |
| Qiong Liu, Jin Yu, Wen-Li Mi, Qi-Liang Mao-Ying, Ru Yang, Yan-Qing Wang, Gen-Cheng W. Electroacupuncture attenuates the decrease of hippocampal progenitor cell proliferation in the adult rats exposed to chronic unpredictable stress. Life sciences. vol 81. issue 21-22. 2008-01-09. PMID:17976657. |
moreover, as shown by 5-bromo-2-deoxyuridine (brdu) labeling immunohistochemistry, hippocampal progenitor cell proliferation was decreased in the dg of depression model rats. |
2008-01-09 |
2023-08-12 |
rat |
| Owain W Howell, Sharmalene Silva, Helen E Scharfman, Alexander A Sosunov, Malik Zaben, Anan Shtaya, Anan Shatya, Guy McKhann, Herbert Herzog, Alexandra Laskowski, William P Gra. Neuropeptide Y is important for basal and seizure-induced precursor cell proliferation in the hippocampus. Neurobiology of disease. vol 26. issue 1. 2007-05-08. PMID:17317195. |
this regulation may be relevant to epilepsy, because seizures increase both npy expression and precursor cell proliferation in the dg. |
2007-05-08 |
2023-08-12 |
mouse |
| Yasuhiko Matsumori, Shwuhuey M Hong, Yang Fan, Takamasa Kayama, Chung Y Hsu, Philip R Weinstein, Jialing Li. Enriched environment and spatial learning enhance hippocampal neurogenesis and salvages ischemic penumbra after focal cerebral ischemia. Neurobiology of disease. vol 22. issue 1. 2006-06-01. PMID:16361108. |
mcao induced a transient increase followed by a sustained depression of progenitor cell proliferation and neuroblast production below baseline level in both ipsilateral and contralateral dg compared to sham. |
2006-06-01 |
2023-08-12 |
rat |
| Kudret Türeyen, Raghu Vemuganti, Kellie K Bowen, Kurt A Sailor, Robert J Dempse. EGF and FGF-2 infusion increases post-ischemic neural progenitor cell proliferation in the adult rat brain. Neurosurgery. vol 57. issue 6. 2006-05-16. PMID:16331174. |
in the present study, we evaluated the additive effect of administering these two factors on post-ischemic progenitor cell proliferation, survival, and phenotypic maturation in the hippocampal dentate gyrus (dg) and the subventricular zone (svz) in the adult rat brain after transient middle cerebral artery occlusion. |
2006-05-16 |
2023-08-12 |
rat |
| Anton B Tonchev, Tetsumori Yamashim. Differential neurogenic potential of progenitor cells in dentate gyrus and CA1 sector of the postischemic adult monkey hippocampus. Experimental neurology. vol 198. issue 1. 2006-04-25. PMID:16426604. |
the adult primate dg also has neurogenic potential under normal conditions, and we have previously shown that transient global cerebral ischemia increases progenitor cell proliferation in monkey dg, with a peak in the second postischemic week. |
2006-04-25 |
2023-08-12 |
monkey |
| Sang Won Suh, Yang Fan, Shwuhuey M Hong, Zhengyan Liu, Yasuhiko Matsumori, Philip R Weinstein, Raymond A Swanson, Jialing Li. Hypoglycemia induces transient neurogenesis and subsequent progenitor cell loss in the rat hippocampus. Diabetes. vol 54. issue 2. 2005-04-11. PMID:15677508. |
a transient increase in progenitor cell proliferation in the dg subgranular zone (sgz) was detected, leading to an increase of immature neuroblasts 1-2 weeks after hypoglycemic insult. |
2005-04-11 |
2023-08-12 |
rat |
| Robert J Dempsey, Kurt A Sailor, Kellie K Bowen, Kudret Türeyen, Raghu Vemugant. Stroke-induced progenitor cell proliferation in adult spontaneously hypertensive rat brain: effect of exogenous IGF-1 and GDNF. Journal of neurochemistry. vol 87. issue 3. 2003-11-24. PMID:14535942. |
at 1 week of reperfusion, mcao-induced progenitor cell proliferation in the ipsilateral dg was significantly increased by i.c.v. |
2003-11-24 |
2023-08-12 |
rat |