Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Zhanghong Zhou, E Tian, Jun Wang, Zhaoqi Guo, Jingyu Chen, Jiaqi Guo, Shiyu Shi, Wandi Xu, Xixi Yu, Caijuan Qiao, Yuejin Zhang, Yisheng Lu, Sulin Zhan. Cognitive impairments and neurobiological changes induced by unilateral vestibular dysfunction in mice. Neurobiology of disease. 2024-10-31. PMID:39481811. |
immunofluorescence staining revealed enhanced activation of c-fos in the hippocampal dentate gyrus (dg) at various time points post-ul, suggesting a role of the hippocampus in cognitive deficits following uvl. |
2024-10-31 |
2024-11-03 |
mouse |
Larissa Marcely Gomes Cassiano, Karina Barbosa de Queiroz, Thais Veronez de Andrade Martins, Ana Luiza Azevedo Maia, Milene Alvarenga Rachid, Sarah J Spencer, Roney Santos Coimbr. Neonatal overfeeding attenuates microgliosis and hippocampal damage in an infant rat model of pneumococcal meningitis. Frontiers in immunology. vol 15. 2024-10-29. PMID:39469711. |
pneumococcal meningitis (pm) triggers apoptotic neuronal and progenitor cell death in the hippocampal dentate gyrus (dg), resulting in subsequent cognitive impairment. |
2024-10-29 |
2024-10-31 |
rat |
Yu-Jui Li, Chia-Wei Yeh, Wahab Imam Abdulmajeed, Musa Iyiola Ajibola, Cheng-Chang Lie. Morpho-physiological Diversity of Cholecystokinin-expressing Interneurons in the Dentate Gyrus. Journal of physiological investigation. vol 67. issue 5. 2024-10-28. PMID:39465567. |
the dg receives multimodal sensory inputs from outside the hippocampus and relays this integrated information to downstream regions for further processing. |
2024-10-28 |
2024-10-30 |
Not clear |
Yu-Jui Li, Chia-Wei Yeh, Wahab Imam Abdulmajeed, Musa Iyiola Ajibola, Cheng-Chang Lie. Morpho-physiological Diversity of Cholecystokinin-expressing Interneurons in the Dentate Gyrus. Journal of physiological investigation. vol 67. issue 5. 2024-10-28. PMID:39465567. |
the hippocampus plays a crucial role in learning, memory, and emotion, with the dentate gyrus (dg) serving as the primary gateway. |
2024-10-28 |
2024-10-30 |
Not clear |
Yu-Jui Li, Chia-Wei Yeh, Wahab Imam Abdulmajeed, Musa Iyiola Ajibola, Cheng-Chang Lie. Morpho-physiological Diversity of Cholecystokinin-expressing Interneurons in the Dentate Gyrus. Journal of physiological investigation. vol 67. issue 5. 2024-10-28. PMID:39465567. |
within the dg, inhibitory gabaergic interneurons (ins) regulate information processing, thereby influencing the overall hippocampal function. |
2024-10-28 |
2024-10-30 |
Not clear |
Yucan Zhu, Hongli Yu, Xiuzhi Zhao, Chunfang Wan. [Analysis of nerve excitability in the dentate gyrus of the hippocampus in cerebral ischaemia-reperfusion mice]. Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi. vol 41. issue 5. 2024-10-27. PMID:39462660. |
in this study, the cerebral ischemia-reperfusion model was built as the experimental object, and the hippocampal dentate gyrus (dg) was the target brain area. |
2024-10-27 |
2024-10-30 |
mouse |
Yucan Zhu, Hongli Yu, Xiuzhi Zhao, Chunfang Wan. [Analysis of nerve excitability in the dentate gyrus of the hippocampus in cerebral ischaemia-reperfusion mice]. Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi. vol 41. issue 5. 2024-10-27. PMID:39462660. |
the resting membrane potential, the number of action potential discharges, the post-hyperpolarization potential and the maximum ascending slope of the hippocampal dg nerve cells in the model mice were significantly lower than those in the control group ( |
2024-10-27 |
2024-10-30 |
mouse |
Yu-Qiu Jiang, Daniel K Lee, Wanyi Guo, Minghua Li, Qian Su. Hypothalamic regulation of hippocampal CA1 interneurons by the supramammillary nucleus. Cell reports. vol 43. issue 11. 2024-10-24. PMID:39446584. |
although the projections from the sum to the dentate gyrus (dg) and ca2 have been extensively studied, whether the sum projects to ca1, the main hippocampal output region, is unclear. |
2024-10-24 |
2024-10-28 |
Not clear |
Maysam Havasi Mehr, Shahein Momenabadi, Ali Vakili, Abbas Pakdel, Abbas Ali Vafae, Abedin Vakil. Neuroprotective effects of Daphnetin on hippocampal neurons and blood-brain barrier integrity in a mouse model of cerebral ischemia. Brain research bulletin. 2024-10-24. PMID:39447767. |
the research found that dap protected neurons in the ca1, ca3, and dg areas of the hippocampus, enhanced behavioral functions, and preserved bbb integrity in a cerebral ischemia model. |
2024-10-24 |
2024-10-28 |
mouse |
Manjyot Kaur, Anju Sharma, Placheril John, Pradeep Bhatnaga. Manifestation of polystyrene microplastic accumulation in brain with emphasis on morphometric and histopathological changes in limbic areas of Swiss albino mice. Neurotoxicology. 2024-10-20. PMID:39427724. |
furthermore, morphometric analysis revealed a significant decrease in the total cell count in the dentate gyrus (dg) and cornu ammonis (ca) regions of the hippocampus. |
2024-10-20 |
2024-10-23 |
mouse |
Jia-Rui Bi, Hai-Wei Zha, Qing-Lin Gao, Hui Wu, Zhen-Jiang Liu, Dong Su. Pleasant Odor Decreases Mouse Anxiety-like Behaviors by Regulating Hippocampal Endocannabinoid Signaling. International journal of molecular sciences. vol 25. issue 19. 2024-10-16. PMID:39409026. |
together, these results uncovered a novel mechanism by which linalool or 2-phenylethanol decreases mouse anxiety-like behaviors and increases dg activity likely through activating hippocampal retrograde endocannabinoid signaling. |
2024-10-16 |
2024-10-18 |
mouse |
Daniel S Scott, Muthumeenakshi Subramanian, Jun Yamamoto, Carol A Tamming. Schizophrenia pathology reverse-translated into mouse shows hippocampal hyperactivity, psychosis behaviors and hyper-synchronous events. Molecular psychiatry. 2024-10-15. PMID:39407000. |
we had previously studied a dentate gyrus (dg)-specific glun1 ko, which displays hippocampal hyperactivity and a psychosis-relevant behavioral phenotype. |
2024-10-15 |
2024-10-18 |
mouse |
Daniel S Scott, Muthumeenakshi Subramanian, Jun Yamamoto, Carol A Tamming. Schizophrenia pathology reverse-translated into mouse shows hippocampal hyperactivity, psychosis behaviors and hyper-synchronous events. Molecular psychiatry. 2024-10-15. PMID:39407000. |
dg inhibition during adolescence generates an increase in hippocampal activity in ca3 and ca1, impairs social cognition and spatial working memory, as well as shows evidence of increased activity in local field potentials as spontaneous synchronous bursts of activity, which we term hyper-synchronous events (hses) in hippocampus. |
2024-10-15 |
2024-10-18 |
mouse |
Daniel S Scott, Muthumeenakshi Subramanian, Jun Yamamoto, Carol A Tamming. Schizophrenia pathology reverse-translated into mouse shows hippocampal hyperactivity, psychosis behaviors and hyper-synchronous events. Molecular psychiatry. 2024-10-15. PMID:39407000. |
these results suggest a sensitive period in development in which the hippocampus is susceptible to dg inhibition resulting in hippocampal hyperactivity and psychosis-like behavioral outcomes. |
2024-10-15 |
2024-10-18 |
mouse |
Jin Jin, Chonglei Fu, Jing Xia, Heyi Luo, Xianglian Wang, Si Chen, Huanhuan Mao, Kai Yuan, Lin Lu, Wei Xiong, Guichang Zo. Cannabidiol ameliorates cognitive decline in 5×FAD mouse model of Alzheimer's disease through potentiating the function of extrasynaptic glycine receptors. Molecular psychiatry. 2024-10-12. PMID:39396064. |
cbd achieves its curative effect mainly through potentiating the function of inhibitory extrasynaptic glycine receptor (glyr) in hippocampal dentate gyrus (dg). |
2024-10-12 |
2024-10-15 |
mouse |
Carolyn Twible, Rober Abdo, Chelsey Zhao, Qi Zhan. Hippocampal dentate granule cells in temporal lobe epilepsy: A morphometry and transcriptomic study. Neuropathology and applied neurobiology. vol 50. issue 5. 2024-10-08. PMID:39375854. |
the dentate gyrus (dg) plays a critical role in hippocampal circuitry, providing a "gate-like" function to the downstream cornu ammonis (ca) sectors. |
2024-10-08 |
2024-10-10 |
Not clear |
Carolyn Twible, Rober Abdo, Chelsey Zhao, Qi Zhan. Hippocampal dentate granule cells in temporal lobe epilepsy: A morphometry and transcriptomic study. Neuropathology and applied neurobiology. vol 50. issue 5. 2024-10-08. PMID:39375854. |
to elucidate the role of the dg in mtle, we analysed hippocampal sclerosis (hs), no-hs, non-tle epilepsy control, and non-epilepsy control cohorts using morphometry and gene expression profiling techniques. |
2024-10-08 |
2024-10-10 |
Not clear |
Stephen B McHugh, Vítor Lopes-Dos-Santos, Manfredi Castelli, Giuseppe P Gava, Sophie E Thompson, Shu K E Tam, Katja Hartwich, Brook Perry, Robert Toth, Timothy Denison, Andrew Sharott, David Dupre. Offline hippocampal reactivation during dentate spikes supports flexible memory. Neuron. 2024-09-25. PMID:39321790. |
hippocampal sharp-wave ripples (swrs) in the cornu ammonis (ca) region and dentate spikes (dss) in the dentate gyrus (dg) are prime candidate network events for supporting this offline process. |
2024-09-25 |
2024-09-28 |
mouse |
Xiuting Qi, Xi Chen, Qi Luo, Lihan Liu, Dong An, Sha Sha, Yimei Du, Chunfeng Wu, Lei Che. TRPV4 Blockage Inhibits the Neurogenesis in the Adult Hippocampal Dentate Gyrus Following Pilocarpine‑Induced Status Epilepticus. Molecular neurobiology. 2024-09-23. PMID:39312069. |
aberrant neurogenesis in the adult hippocampal dentate gyrus (dg) contributes to synapse remodeling during temporal lobe epilepsy (tle). |
2024-09-23 |
2024-09-26 |
mouse |
Xiuting Qi, Xi Chen, Qi Luo, Lihan Liu, Dong An, Sha Sha, Yimei Du, Chunfeng Wu, Lei Che. TRPV4 Blockage Inhibits the Neurogenesis in the Adult Hippocampal Dentate Gyrus Following Pilocarpine‑Induced Status Epilepticus. Molecular neurobiology. 2024-09-23. PMID:39312069. |
activation of trpv4 can modulate neurogenesis in the adult hippocampal dg. |
2024-09-23 |
2024-09-26 |
mouse |