| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sena Hatori, Sho T Yamaguchi, Riho Kobayashi, Kazuki Okamoto, Zhiwen Zhou, Koki T Kotake, Futaba Matsui, Hiroyuki Hioki, Hiroaki Norimot. Sleep homeostasis in lizards and the role of the cortex. Proceedings of the National Academy of Sciences of the United States of America. vol 122. issue 16. 2025-04-17. PMID:40244675. |
slow waves in the cortex not only characterize sws but are also used as biological markers for sleep homeostasis, given their rebound after sleep deprivation (sd). |
2025-04-17 |
2025-04-19 |
Not clear |
| Xue Wang, Xinrui Liu, Shuang Chen, Jiang Zhu, Yanqi Yuan, Rong Zhu, Kaixi Chen, Xue Yang, Xiaochun Wang, Weiyi Mo, Ruili Wang, Shuoxin Zhan. Elevational variation in anatomical traits of the first-order roots and their adaptation mechanisms. Plant diversity. vol 47. issue 2. 2025-04-04. PMID:40182480. |
to determine how plants change root anatomical traits to adapt to distinct environments, we measured four key root anatomical traits-stele diameter (sd), cortex thickness (ct), root diameter (rd), and the stele to root diameter ratio (sdrd)-of first-order roots of 82 species collected from different vegetation zones along a 2000 m altitudinal gradient on the northern slope of taibai mountain. |
2025-04-04 |
2025-04-06 |
Not clear |
| Isamu Aiba, Yao Ning, Jeffrey L Noebel. Persistent Na+ current couples spreading depolarization to seizures in Scn8a gain of function mice. Brain : a journal of neurology. 2025-04-03. PMID:40177888. |
while sd typically arises as an isolated hemispheric event, we previously reported that reducing m-type potassium current (ikm) by ablation of kcnq2 in forebrain excitatory neurons results in tightly coupled spontaneous bilateral seizure-sd complexes in the awake mouse cortex. |
2025-04-03 |
2025-04-04 |
mouse |
| Isamu Aiba, Yao Ning, Jeffrey L Noebel. Persistent Na+ current couples spreading depolarization to seizures in Scn8a gain of function mice. Brain : a journal of neurology. 2025-04-03. PMID:40177888. |
laser speckle contrast imaging of cerebral blood flow dynamics resolved sd as a bilateral wave of hypoperfusion and subsequent hour-lasting hypoperfusion in scn8ad/+ cortex in awake head-restrained mice evoked by a ptz injection. |
2025-04-03 |
2025-04-04 |
mouse |
| Sreekar Puchala, Ethan Muchnik, Anca Ralescu, Jed A Harting. Automated detection of spreading depolarizations in electrocorticography. Scientific reports. vol 15. issue 1. 2025-03-13. PMID:40074765. |
spreading depolarizations (sd) in the cerebral cortex are a novel mechanism of lesion development and worse outcomes after acute brain injury, but accurate diagnosis by neurophysiology is a barrier to more widespread application in neurocritical care. |
2025-03-13 |
2025-03-15 |
Not clear |
| Wenwen Wu, Zengyu Wei, Zhiyun Wu, Jianmin Chen, Ji Liu, Manli Chen, Jinjin Yuan, Zhijian Zheng, Zijun Zhao, Qiang Lin, Nan Liu, Hongbin Che. Exercise training alleviates neuronal apoptosis and re-establishes mitochondrial quality control after cerebral ischemia by increasing SIRT3 expression. Cell biology and toxicology. vol 41. issue 1. 2024-12-20. PMID:39707047. |
male adult sd rats received tmcao after the transfection of adeno-associated virus encoding either sirtuin-3 (aav-sirt3) or sirt3 knockdown (aav-sh-sirt3) into the ipsilateral striata and cortex. |
2024-12-20 |
2024-12-24 |
rat |
| Wenkai Yu, Xinyu Li, Chan Zhang, Pengpeng Niu, Jinghao Wu, Wenjun He, Kai Gao, Yuming Xu, Yusheng L. KDM6B knockdown alleviates sleep deprivation-induced cerebrovascular lesions in APP/PS1 mice by inhibiting PARP16 expression. Biochemical pharmacology. 2024-11-27. PMID:39603516. |
in addition, sd led to a significant increase in the expression of kdm6b in the cerebral cortex of app/ps1 mice. |
2024-11-27 |
2024-11-30 |
mouse |
| Nils Hecht, Daisy Haddad, Konrad Neumann, Leonie Schumm, Nora F Dengler, Lars Wessels, Patrick Dömer, Simeon Helgers, Franziska Meinert, Sebastian Major, Coline L Lemale, Jens P Dreier, Peter Vajkoczy, Johannes Woitzi. Reduced brain oxygen response to spreading depolarization predicts worse outcome in ischaemic stroke. Brain : a journal of neurology. 2024-11-14. PMID:39538992. |
spreading depolarization (sd) describes a propagating neuronal mass depolarization within the cerebral cortex that represents a mediator of infarct development and strongly stimulates the metabolic rate of o2 consumption. |
2024-11-14 |
2024-11-17 |
Not clear |
| Marie Bockenstedt, Amit Kumar, Victoria Laast, Alok Sharm. Historical Control Background Incidence of Spontaneous Nonneoplastic Lesions of Sprague Dawley Rats in 104-Week Carcinogenicity Studies. Toxicologic pathology. 2024-10-29. PMID:39469803. |
the most common nonnenoplastic findings in female sd rats were cystic degeneration of the adrenal cortex (64.7%) and ventral compression of the brain due to pituitary neoplasms (62.7%). |
2024-10-29 |
2024-10-31 |
rat |
| Cai-Rong Zhao, Xiang-Long Meng, Juan Wang, Hong-Yu Zhao, Xiang Han, Zi-Ang Li, Shuo-Sheng Zhan. [Immune mechanism of Daphnes Cortex and its processed products on CIA rats based on B7/CD28/CTLA-4 pathway]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 49. issue 15. 2024-09-22. PMID:39307741. |
this study investigates the effects of daphnes cortex and its processed products on the differentiation of th17/treg cells in sd rats with type Ⅱ collagen-induced arthritis(cia).sixty-four sd rats were randomly divided into the normal group(normal),model group(model),fried daphne giraldii nitsche low-dose and high-dose groups(fdgn-l group, fdgn-h group),raw d. giraldii nitsche low-dose and high-dose groups(rdgn-l group, rdgn-h group),daphnetin group(daph group),and tripterygium glycosides group(gtw group).except for the normal group, the cia model was immunized on the seventh day after the first immunization, and was gavaged for 28 days after the second immunization.after sampling, the inflammation of articular synovial membrane in cia rats was observed by hematoxylin-eosin(he)staining; the levels of transforming growth factor-β(tgf-β),interferon-γ(ifn-γ),interleukin(il)-2,il-4,and il-10 in serum were detected by enzyme-linked immunosorbent assay(elisa); real-time reverse transcription-pcr(qrt-pcr)and western blot were used to detect the mrna and protein expressions of cluster of differentiation(cd) 80(b7-1),cd 86(b7-2),cd28,and cytotoxic t lymphocyte-associated antigen 4(ctla-4)in the synovial membrane of rats; flow cytometry was used to detect the proportion of th17 and treg cells in the synovial membrane of rats.the results showed that compared with the normal group, the joint synovial inflammation of rats in the model group was significantly aggravated, the arthritis index was significantly increased, and the immune organ index was increased(p<0.01).compared with the model group, each drug administration group could improve the joint inflammation of rats to varying degrees, reduce the arthritis index, inhibit synovial hyperplasia, and reduce the immune organ index; compared with the model group, the serum levels of il-2 and ifn-γ in each drug administration group were significantly decreased(p<0.01),tgf-β,il-4,and il-10 were significantly increased(p<0.01),the mrna and protein expressions of b7-1 and ctla-4 in the synovial membrane were significantly increased(p<0.01),and the proportion of th17 cells and treg cells in the joint tissue was significantly decreased(p<0.01).in conclusion, daphnes cortex inhibits the expression of th17 cells in cia rats and promotes the expression of treg cells by regulating the b7/cd28/ctla-4 pathway and the balance of th17/treg, thereby treating rheumatoid arthritis. |
2024-09-22 |
2024-09-26 |
rat |
| Ruicheng Zhang, Lei Zhang, Wenqi Du, Jiao Tang, Long Yang, Deqin Geng, Yanbo Chen. Caffeine alleviate lipopolysaccharide-induced neuroinflammation and depression through regulating p-AKT and NF-κB. Neuroscience letters. 2024-08-06. PMID:39106918. |
open-filed and closed-field tests were applied to detect the behaviors of sd rats, while western blot was performed to measure the phosphorylation level of protein kinase b (p-akt) and nuclear factor κb (nf-κb) in the cortex after caffeine was orally administered. |
2024-08-06 |
2024-08-09 |
rat |
| Ruicheng Zhang, Lei Zhang, Wenqi Du, Jiao Tang, Long Yang, Deqin Geng, Yanbo Chen. Caffeine alleviate lipopolysaccharide-induced neuroinflammation and depression through regulating p-AKT and NF-κB. Neuroscience letters. 2024-08-06. PMID:39106918. |
mechanistic investigations demonstrated that caffeine down-regulated the expression of p-akt and nf-κb in lps-induced sd rats cortex. |
2024-08-06 |
2024-08-09 |
rat |
| Jeremy Sword, Ioulia V Fomitcheva, Sergei A Kiro. Spreading depolarization causes reversible neuronal mitochondria fragmentation and swelling in healthy, normally perfused neocortex. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2024-07-25. PMID:39053498. |
in the normoxic cortex, spreading depolarization (sd) is a phenomenon underlying migraine aura. |
2024-07-25 |
2024-07-28 |
Not clear |
| Luciane da Silva Gonçalves, Gabriela Rusch, Amália Gonçalves Alves, Letícia Devantier Krüger, Mariana Parron Paim, Carolina Cristóvão Martins, Ketlyn Pereira da Motta, José Sebastião Dos Santos Neto, Cristiane Luchese, Ethel Antunes Wilhelm, César Augusto Brüning, Cristiani Folharini Bortolatt. Acute 2-phenyl-3-(phenylselanyl)benzofuran treatment reverses the neurobehavioral alterations induced by sleep deprivation in mice. Biochemical pharmacology. 2024-06-07. PMID:38848781. |
sebzf1 also reverted the increase in lipoperoxidation levels and glutathione peroxidase activity in the pre-frontal cortex in mice exposed to sd. |
2024-06-07 |
2024-06-10 |
mouse |
| Yanzhe Ning, Sitong Feng, Sisi Zheng, Ziyao Wu, Xinzi Liu, Linrui Dong, Hongxiao Ji. How BDNF affects working memory in acute sleep deprivation: The mediating role of spontaneous brain activity. Sleep medicine. vol 118. 2024-04-02. PMID:38564888. |
our results suggest that the association between bdnf and working memory may be mediated through regional spontaneous brain activity involving in the cerebral cortex, which may provide new sight into the interaction between neurotrophic factors and cognition, and potential targets for noninvasive brain stimulation on wm decline after acute sd. |
2024-04-02 |
2024-04-05 |
human |
| Jeremy Sword, Ioulia V Fomitcheva, Sergei A Kiro. Spreading depolarization causes reversible neuronal mitochondria fragmentation and swelling in healthy, normally perfused neocortex. bioRxiv : the preprint server for biology. 2024-02-08. PMID:38328069. |
in the normoxic cortex, spreading depolarization (sd) is a phenomenon underlying migraine aura. |
2024-02-08 |
2024-02-10 |
Not clear |
| Xinyi Liu, Wenjia Zhang, Jie Dong, Zhiqiang Yan, Qiufeng Dong, Jing Feng, Yaling Lai, Hao Ya. Effects of sleep deprivation on language-related brain functional connectivity: differences by gender and age. Cognitive, affective & behavioral neuroscience. 2024-01-25. PMID:38273105. |
specifically, there were gender differences in the temporal association cortex and age differences in the parietal association cortex, during full sleep versus partial sd. |
2024-01-25 |
2024-01-28 |
Not clear |
| Bingcong Li, Yin-Ru Hsieh, Wen-De Lai, Te-Hsuan Tung, Yu-Xuan Chen, Chia-Hui Yang, Yu-Chiao Fang, Shih-Yi Huan. Melatonin Ameliorates Neuropsychiatric Behaviors, Gut Microbiome, and Microbiota-Derived Metabolites in Rats with Chronic Sleep Deprivation. International journal of molecular sciences. vol 24. issue 23. 2023-12-09. PMID:38069141. |
four-week sd reduced the cerebral cortex expression of mt1, but not in the colon. |
2023-12-09 |
2023-12-17 |
rat |
| Giulia Siena, Francesca di Nardo, Barbara Contiero, Tommaso Banzato, Chiara Milan. Preliminary Evaluation of Cortical and Medullary Echogenicity in Normal Canine Fetal Kidneys during the Last 10 Days of Pregnancy. Veterinary sciences. vol 10. issue 11. 2023-11-26. PMID:37999462. |
the mean gray level (mgl) and sd of a manually drawn region of interest (roi) in the renal cortex and medulla were measured using the fiji image j software (image j 1.51h, java 1.6 0_24 64 bit). |
2023-11-26 |
2023-11-28 |
Not clear |
| James Hubbard, David Berry, Aakash Chauhan, Chris Casstevens, Alexander Y Shin, Reid A Abram. A three-dimensional computed tomography study of the palmar ulnar corner fragment in distal radial fractures. The Journal of hand surgery, European volume. 2023-11-17. PMID:37974338. |
three types emerged: type 1 fragments involved 37% (sd 10) of the radiocarpal articular surface and were extended in the sagittal plane; type 2 fragments involved 28% (sd 10) of the articular surface and had a long palmar cortex, of which 57% had palmar carpal subluxation; and type 3 fragments involved 13% (sd 2) of the articular surface, had a short palmar cortex and all had palmar carpal subluxation. |
2023-11-17 |
2023-11-20 |
Not clear |