| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mohammad Amin Fakharian, Alden M Shoup, Paul Hage, Hisham Y Elseweifi, Reza Shadmeh. A vector calculus for neural computation in the cerebellum. bioRxiv : the preprint server for biology. 2024-11-28. PMID:39605699. |
here, we found that in the marmoset cerebellum, spike-triggered averaging identified a potent vector unique to each purkinje cell (p-cell) along which the spikes of that cell displaced the eyes. |
2024-11-28 |
2024-11-30 |
marmoset |
| Nagham Khouri-Farah, Qiuxia Guo, Thomas A Perry, Ryan Dussault, James Y H L. bioRxiv : the preprint server for biology. 2024-11-22. PMID:39574602. |
mammalian cerebellar development is thought to be influenced by distinct purkinje cell (pc) subtypes. |
2024-11-22 |
2024-11-24 |
Not clear |
| Hiroshi Nishiyama, Naoko Nishiyama, Boris V Zemelma. Purkinje cell ablation and Purkinje cell-specific deletion of Tsc1 in the developing cerebellum strengthen cerebellothalamic synapses. The Journal of physiology. 2024-11-19. PMID:39558452. |
purkinje cell ablation and purkinje cell-specific deletion of tsc1 in the developing cerebellum strengthen cerebellothalamic synapses. |
2024-11-19 |
2024-11-22 |
mouse |
| Silas E Busch, Christian Hanse. Non-allometric expansion and enhanced compartmentalization of Purkinje cell dendrites in the human cerebellum. bioRxiv : the preprint server for biology. 2024-11-18. PMID:39554002. |
non-allometric expansion and enhanced compartmentalization of purkinje cell dendrites in the human cerebellum. |
2024-11-18 |
2024-11-22 |
mouse |
| Silas E Busch, Christian Hanse. Non-allometric expansion and enhanced compartmentalization of Purkinje cell dendrites in the human cerebellum. bioRxiv : the preprint server for biology. 2024-11-18. PMID:39554002. |
purkinje cell (pc) dendrites are optimized to integrate the vast cerebellar input array and drive the sole cortical output. |
2024-11-18 |
2024-11-22 |
mouse |
| Bernardo Flores-Prieto, Flower Caycho-Salazar, Jorge Manzo, María Elena Hernández-Aguilar, Alfonso Genaro Coria-Avila, Deissy Herrera-Covarrubias, Fausto Rojas-Dúran, Gonzalo Emiliano Aranda-Abreu, Cesar Antonio Pérez-Estudillo, María Rebeca Toledo-Cárdena. Effect of Enriched Environment on Cerebellum and Social Behavior of Valproic Zebrafish. NeuroSci. vol 5. issue 2. 2024-11-01. PMID:39483495. |
to test this hypothesis, we assessed social behavior, cerebellar volume, and purkinje cell populations via histology and immunohistochemistry after exposing the fish to ee. |
2024-11-01 |
2024-11-03 |
zebrafish |
| Katherine A Inskeep, Bryan Crase, Thamara Dayarathna, Rolf W Stottman. SMPD4 mediated sphingolipid metabolism regulates brain and primary cilia development. Development (Cambridge, England). 2024-10-29. PMID:39470011. |
we found that the mouse model has cerebellar hypoplasia due to failure of purkinje cell development. |
2024-10-29 |
2024-10-31 |
mouse |
| Moe Tanigawa, Mengke Liu, Mariko Sekiguchi, Kyosuke Goda, Chiho Kato, Takashi Ono, Naofumi Uesak. Nasal obstruction during development leads to defective synapse elimination, hypersynchrony, and impaired cerebellar function. Communications biology. vol 7. issue 1. 2024-10-24. PMID:39443666. |
our study also reveals that nasal obstruction in mice disrupts the typical developmental process of synapse elimination in the cerebellum and hinders the normal transition of activity patterns in cerebellar purkinje cell populations during development. |
2024-10-24 |
2024-10-26 |
mouse |
| Moe Tanigawa, Mengke Liu, Mariko Sekiguchi, Kyosuke Goda, Chiho Kato, Takashi Ono, Naofumi Uesak. Nasal obstruction during development leads to defective synapse elimination, hypersynchrony, and impaired cerebellar function. Communications biology. vol 7. issue 1. 2024-10-24. PMID:39443666. |
through comparing activity patterns in mouse models subjected to nasal obstruction at various stages, we suggest that the maturation of specific activity pattern among purkinje cell populations is fundamental to the functional integrity of the cerebellum. |
2024-10-24 |
2024-10-26 |
mouse |
| Vinícius Pedro Silva de Oliveira, Tais Harumi de Castro Sasahara, Gabriela Salim de Castro, Lara Carolina Mario, Bruno Cesar Schimming, José Roberto Kfoury Júnior, Silvio Pires Gome. Stereological Study of Cerebellar Morphology in Feline Fetuses: Insights from the Final Gestational Stage. Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft. 2024-09-19. PMID:39299656. |
using stereology, the following parameters were determined: cerebellar volume, averaging 0.847cm³; volume density of the cortex: 0.496 or 49% (molecular layer), 0.0314 or 3.14% (purkinje cell layer), 0.232 or 23% (granular layer), and 0.234 or 23% (medullary white center). |
2024-09-19 |
2024-09-22 |
cat |
| Samaneh Rahdar, Zahra Basir, Mohammad Reza Tabandeh, Zohreh Ghotbeddin, Kaveh Khazaee. Betaine alleviates cerebellar endoplasmic reticulum stress and oxidative imbalance in a cuprizone model of multiple sclerosis in rat. Naunyn-Schmiedeberg's archives of pharmacology. 2024-09-09. PMID:39249501. |
betaine treatment protected cerebellar demyelination and neuron and purkinje cell degeneration against cpz-induced demyelination. |
2024-09-09 |
2024-09-11 |
rat |
| Elan D Louis, Sheng-Han Kuo, Phyllis L Faus. Purkinje Cell Dendritic Swellings: A Postmortem Study of Essential Tremor and Other Cerebellar Degenerative Disorders. Cerebellum (London, England). 2024-09-04. PMID:39230844. |
purkinje cell dendritic swellings: a postmortem study of essential tremor and other cerebellar degenerative disorders. |
2024-09-04 |
2024-09-06 |
Not clear |
| Michalina Hanzel, Kayla Fernando, Susan E Maloney, Zachi Horn, Shiaoching Gong, Kärt Mätlik, Jiajia Zhao, H Amalia Pasolli, Søren Heissel, Joseph D Dougherty, Court Hull, Mary E Hatte. Mice lacking Proceedings of the National Academy of Sciences of the United States of America. vol 121. issue 34. 2024-08-16. PMID:39150780. |
mice lacking astrotactin 2 (astn2) is a transmembrane neuronal protein highly expressed in the cerebellum that functions in receptor trafficking and modulates cerebellar purkinje cell (pc) synaptic activity. |
2024-08-16 |
2024-08-19 |
mouse |
| Cole King, Tessa Maze, Bethany Plakk. Altered prefrontal and cerebellar parvalbumin neuron counts are associated with cognitive changes in male rats. Experimental brain research. 2024-07-31. PMID:39085433. |
people with asd often display changes in the cerebellum, including volume changes, altered circuitry, and changes in purkinje cell populations. |
2024-07-31 |
2024-08-03 |
rat |
| Cole King, Tessa Maze, Bethany Plakk. Altered prefrontal and cerebellar parvalbumin neuron counts are associated with cognitive changes in male rats. Experimental brain research. 2024-07-31. PMID:39085433. |
inhibitory parvalbumin-expressing (pv +) neuron counts were assessed in the mpfc and cerebellar lobules vi and vii (purkinje cell layers), which are known to modulate cognition. |
2024-07-31 |
2024-08-03 |
rat |
| Elías Mateo Fernández Santoro, Arun Karim, Pascal Warnaar, Chris I De Zeeuw, Aleksandra Badura, Mario Negrell. Purkinje cell models: past, present and future. Frontiers in computational neuroscience. vol 18. 2024-07-26. PMID:39049990. |
the investigation of the dynamics of purkinje cell (pc) activity is crucial to unravel the role of the cerebellum in motor control, learning and cognitive processes. |
2024-07-26 |
2024-07-28 |
Not clear |
| Lin-Yan Huang, Yi-Ning Liu, Jie Chen, Hai-Xue Zhu, Li-Li Li, Zhi-Yan Liang, Jin-Xiu Song, Yu-Jie Li, Zhao-Li Hu, Dieter Demon, Andy Wullaert, Wan Wang, Su-Hua Q. Caspase-12 is Expressed in Purkinje Neurons and Prevents Psychiatric-Like Behavior in Mice. Molecular neurobiology. 2024-07-18. PMID:39023795. |
extensive histological analyses showed that caspase-12 was not crucial for establishing cerebellum structure or for maintaining purkinje cell numbers. |
2024-07-18 |
2024-07-20 |
mouse |
| Kim M Gruver, Jenny W Y Jiao, Eviatar Fields, Sen Song, Per Jesper Sjöström, Alanna J Wat. Structured connectivity in the output of the cerebellar cortex. Nature communications. vol 15. issue 1. 2024-07-09. PMID:38982047. |
we observed non-random connectivity where purkinje cell inputs clustered in cerebellar transverse zones: while many nuclear neurons received inputs from a single zone, several multi-zonal connectivity motifs were also observed. |
2024-07-09 |
2024-07-12 |
mouse |
| Luke C Bartelt, Mouad Fakhri, Grazyna Adamek, Magdalena Trybus, Anna Samelak-Czajka, Paulina Jackowiak, Agnieszka Fiszer, Craig B Lowe, Albert R La Spada, Pawel M Switonsk. Antibody-assisted selective isolation of Purkinje cell nuclei from mouse cerebellar tissue. Cell reports methods. 2024-07-09. PMID:38981474. |
antibody-assisted selective isolation of purkinje cell nuclei from mouse cerebellar tissue. |
2024-07-09 |
2024-07-12 |
mouse |
| Kaija J Autio, Hennariikka Koivisto, Werner Schmitz, Anna Puronurmi, Heikki Tanila, Alexander J Kastanioti. Exploration of dietary interventions to treat mitochondrial fatty acid disorders in a mouse model. The Journal of nutritional biochemistry. 2024-06-15. PMID:38879137. |
the neurological status on the mice was assessed at the age of 3, 6 and 9 months with behavioral tests and the state of the purkinje cell deterioration in the cerebellum was studied histologically. |
2024-06-15 |
2024-06-18 |
mouse |