| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yingxi Chen, Jie Sheng, Xiuying Tang, Yuhong Zhao, Shujuan Zhu, Qian Li. Clemastine Rescues Chemotherapy-Induced Cognitive Impairment by Improving White Matter Integrity. Neuroscience. 2022-01-10. PMID:35007691. |
clemastine enhanced myelination, promoted oligodendrocyte precursor cell differentiation and increased the neurofilament 200 protein levels in the corpus callosum and hippocampus. |
2022-01-10 |
2023-08-13 |
mouse |
| Thomas H Lee, Ahadullah, Brian R Christie, Kangguang Lin, Parco Ming-Fai Siu, Li Zhang, Ti-Fei Yuan, Pragya Komal, Aimin Xu, Kwok-Fai So, Suk-Yu Ya. Chronic AdipoRon Treatment Mimics the Effects of Physical Exercise on Restoring Hippocampal Neuroplasticity in Diabetic Mice. Molecular neurobiology. vol 58. issue 9. 2021-10-15. PMID:34164760. |
besides, adiporon treatment increased progenitor cell proliferation and neuronal differentiation in the hippocampal dentate gyrus (dg) of diabetic mice. |
2021-10-15 |
2023-08-13 |
mouse |
| Yuxin Wang, Yixun Su, Guangdan Yu, Xiaorui Wang, Xiaoying Chen, Bin Yu, Yijun Cheng, Rui Li, Juan C Sáez, Chenju Yi, Lan Xiao, Jianqin Ni. Reduced Oligodendrocyte Precursor Cell Impairs Astrocytic Development in Early Life Stress. Advanced science (Weinheim, Baden-Wurttemberg, Germany). vol 8. issue 16. 2021-09-02. PMID:34155833. |
in this study, it is shown that a reduced oligodendrocyte precursor cell (opc) population accompanies hindered hippocampal astrocytic development in an improved parental isolation mouse model, and that the loss of opcs suppresses astrocytic network formation and activity. |
2021-09-02 |
2023-08-13 |
mouse |
| Justus Baecker, Krista Wartchow, Tina Sehm, Ali Ghoochani, Michael Buchfelder, Andrea Kleindiens. Treatment with the Neurotrophic Protein S100B Increases Synaptogenesis after Traumatic Brain Injury. Journal of neurotrauma. vol 37. issue 8. 2021-08-18. PMID:31597524. |
although nanomolar s100b concentrations enhance hippocampal progenitor cell proliferation, neuronal differentiation, and cognitive recovery, micromolar concentrations may foster inflammatory effects counteracting neuroplasticity. |
2021-08-18 |
2023-08-13 |
rat |
| Muhammad M Hossain, Abdelmadjid Belkadi, Sara Al-Haddad, Jason R Richardso. Deltamethrin Exposure Inhibits Adult Hippocampal Neurogenesis and Causes Deficits in Learning and Memory in Mice. Toxicological sciences : an official journal of the Society of Toxicology. vol 178. issue 2. 2021-08-13. PMID:32976580. |
deficits in learning and memory are often associated with disruption of hippocampal neurogenesis, which is regulated by numerous processes, including precursor cell proliferation, survival, migration, and differentiation to mature neurons. |
2021-08-13 |
2023-08-13 |
mouse |
| Hyunah Lee, Amelie Metz, Amina McDiarmid, Alish Palmos, Sang H Lee, Charles J Curtis, Hamel Patel, Stephen J Newhouse, Sandrine Thure. The effects of genotype on inflammatory response in hippocampal progenitor cells: A computational approach. Brain, behavior, & immunity - health. vol 15. 2021-08-06. PMID:34345870. |
to investigate how the genetic makeup of a cell line might affect the cellular response to inflammation, we characterised the single nucleotide variants (snps) relevant to inflammation-related genes in an established hippocampal progenitor cell line (hpc0a07/03c) that is frequently used as an in vitro model for hippocampal neurogenesis (hn). |
2021-08-06 |
2023-08-13 |
Not clear |
| Shengjun Ji, Haohao Wu, Xin Ding, Qingqing Chen, Xing Jin, Jinming Yu, Ming Yan. Increased hippocampal TrkA expression ameliorates cranial radiation‑induced neurogenesis impairment and cognitive deficit via PI3K/AKT signaling. Oncology reports. vol 44. issue 6. 2021-07-30. PMID:33125501. |
additionally, upregulating trka expression rescued irradiation‑induced hippocampal precursor cell proliferation and promoted neurogenesis. |
2021-07-30 |
2023-08-13 |
rat |
| Alessandra Borsini, Doris Stangl, Aaron R Jeffries, Carmine M Pariante, Sandrine Thure. The role of omega-3 fatty acids in preventing glucocorticoid-induced reduction in human hippocampal neurogenesis and increase in apoptosis. Translational psychiatry. vol 10. issue 1. 2021-06-18. PMID:32636362. |
we used the human hippocampal progenitor cell line hpc0a07/03c and pre-treated cells with either epa or dha, followed by treatment with the glucocorticoid cortisol either alone, or in co-treatment with the same n-3 pufa during subsequent 3 days of proliferation and 7 days of differentiation. |
2021-06-18 |
2023-08-13 |
human |
| Alessandra Borsini, Anna Nicolaou, Dolores Camacho-Muñoz, Alexandra C Kendall, Maria Grazia Di Benedetto, Juliette Giacobbe, Kuan-Pin Su, Carmine M Pariant. Omega-3 polyunsaturated fatty acids protect against inflammation through production of LOX and CYP450 lipid mediators: relevance for major depression and for human hippocampal neurogenesis. Molecular psychiatry. 2021-06-16. PMID:34131267. |
in vitro, we used the human hippocampal progenitor cell line hpc0a07/03c, and pre-treated cells with either epa or dha, followed by interleukin 1beta (il1β), il6 and interferon-alpha (ifn-α). |
2021-06-16 |
2023-08-13 |
human |
| Demelza M Smeeth, Ioanna Kourouzidou, Rodrigo R R Duarte, Timothy R Powell, Sandrine Thure. Prolactin, Estradiol and Testosterone Differentially Impact Human Hippocampal Neurogenesis in an In Vitro Model. Neuroscience. vol 454. 2021-05-14. PMID:31930958. |
here, we quantify the expression levels of the relevant receptors in human post-mortem hippocampal tissue and a human hippocampal progenitor cell (hpc) line. |
2021-05-14 |
2023-08-13 |
human |
| Sara Zocher, Gerd Kemperman. Generation of mouse hippocampal neural precursor cell lines with CRISPR/Cas9-mediated gene knockouts. STAR protocols. vol 2. issue 2. 2021-05-07. PMID:33948565. |
generation of mouse hippocampal neural precursor cell lines with crispr/cas9-mediated gene knockouts. |
2021-05-07 |
2023-08-13 |
mouse |
| Qiang Liu, Hao-Wen Lv, Shu Yang, Yu-Qing He, Quan-Rui Ma, Juan Li. NEP1-40 alleviates behavioral phenotypes and promote oligodendrocyte progenitor cell differentiation in the hippocampus of cuprizone-induced demyelination mouse model. Neuroscience letters. vol 725. 2021-04-19. PMID:32112820. |
nep1-40 alleviates behavioral phenotypes and promote oligodendrocyte progenitor cell differentiation in the hippocampus of cuprizone-induced demyelination mouse model. |
2021-04-19 |
2023-08-13 |
mouse |
| Vikki Houghton, Andrea Du Preez, Sophie Lefèvre-Arbogast, Chiara de Lucia, Dorrain Y Low, Mireia Urpi-Sarda, Silvie R Ruigrok, Barbara Altendorfer, Raúl González-Domínguez, Cristina Andres-Lacueva, Ludwig Aigner, Paul J Lucassen, Aniko Korosi, Cécilia Samieri, Claudine Manach, Sandrine Thure. Caffeine Compromises Proliferation of Human Hippocampal Progenitor Cells. Frontiers in cell and developmental biology. vol 8. 2021-03-10. PMID:33015033. |
here, we used a human hippocampal progenitor cell line to investigate the effects of caffeine on hippocampal progenitor integrity and proliferation specifically. |
2021-03-10 |
2023-08-13 |
human |
| John B Redell, Mark E Maynard, Erica L Underwood, Sydney M Vita, Pramod K Dash, Nobuhide Kobor. Traumatic brain injury and hippocampal neurogenesis: Functional implications. Experimental neurology. vol 331. 2021-02-11. PMID:32504636. |
experimental traumatic brain injury (tbi) in rodents has been shown to alter hippocampal neurogenesis, including triggering the acute loss of newborn neurons, as well as progenitor cell hyper-proliferation. |
2021-02-11 |
2023-08-13 |
Not clear |
| Odette Leiter, Stefanie N Bernas, Suse Seidemann, Rupert W Overall, Cindy Horenburg, Susann Kowal, Gerd Kempermann, Tara L Walke. The systemic exercise-released chemokine lymphotactin/XCL1 modulates in vitro adult hippocampal precursor cell proliferation and neuronal differentiation. Scientific reports. vol 9. issue 1. 2020-11-09. PMID:31413355. |
the systemic exercise-released chemokine lymphotactin/xcl1 modulates in vitro adult hippocampal precursor cell proliferation and neuronal differentiation. |
2020-11-09 |
2023-08-13 |
mouse |
| Nadine Provençal, Janine Arloth, Annamaria Cattaneo, Christoph Anacker, Nadia Cattane, Tobias Wiechmann, Simone Röh, Maik Ködel, Torsten Klengel, Darina Czamara, Nikola S Müller, Jari Lahti, Katri Räikkönen, Carmine M Pariante, Elisabeth B Binde. Glucocorticoid exposure during hippocampal neurogenesis primes future stress response by inducing changes in DNA methylation. Proceedings of the National Academy of Sciences of the United States of America. vol 117. issue 38. 2020-11-06. PMID:31399550. |
in a human hippocampal progenitor cell (hpc) line, we assessed the short- and long-term effects of gc exposure during neurogenesis on messenger rna (mrna) expression and dna methylation (dnam) profiles. |
2020-11-06 |
2023-08-13 |
human |
| Lin Li, Mohammad Ghorbani, Monika Weisz-Hubshman, Justine Rousseau, Isabelle Thiffault, Rhonda E Schnur, Catherine Breen, Renske Oegema, Marjan Mm Weiss, Quinten Waisfisz, Sara Welner, Helen Kingston, Jordan A Hills, Elles Mj Boon, Lina Basel-Salmon, Osnat Konen, Hadassa Goldberg-Stern, Lily Bazak, Shay Tzur, Jianliang Jin, Xiuli Bi, Michael Bruccoleri, Kirsty McWalter, Megan T Cho, Maria Scarano, G Bradley Schaefer, Susan S Brooks, Susan Starling Hughes, K L I van Gassen, Johanna M van Hagen, Tej K Pandita, Pankaj B Agrawal, Philippe M Campeau, Xiang-Jiao Yan. Lysine acetyltransferase 8 is involved in cerebral development and syndromic intellectual disability. The Journal of clinical investigation. vol 130. issue 3. 2020-11-03. PMID:31794431. |
here, we report that cerebrum-specific knockout mice displayed cerebral hypoplasia in the neocortex and hippocampus, along with improper neural stem and progenitor cell (nspc) development. |
2020-11-03 |
2023-08-13 |
mouse |
| James Fraser, Alexandra Essebier, Alexander S Brown, Raul Ayala Davila, Danyon Harkins, Oressia Zalucki, Lauren P Shapiro, Peter Penzes, Brandon J Wainwright, Matthew P Scott, Richard M Gronostajski, Mikael Bodén, Michael Piper, Tracey J Harve. Common Regulatory Targets of NFIA, NFIX and NFIB during Postnatal Cerebellar Development. Cerebellum (London, England). vol 19. issue 1. 2020-10-23. PMID:31838646. |
for instance, transcription factors from the nuclear factor i (nfi) family have been shown to co-ordinate neural stem and progenitor cell differentiation within multiple regions of the embryonic nervous system, including the neocortex, hippocampus, spinal cord and cerebellum. |
2020-10-23 |
2023-08-13 |
Not clear |
| Daniela M S Moura, Juliana Alves Brandão, Celia Lentini, Christophe Heinrich, Claudio M Queiroz, Marcos R Cost. Evidence of Progenitor Cell Lineage Rerouting in the Adult Mouse Hippocampus After Status Epilepticus. Frontiers in neuroscience. vol 14. 2020-10-22. PMID:33071745. |
evidence of progenitor cell lineage rerouting in the adult mouse hippocampus after status epilepticus. |
2020-10-22 |
2023-08-13 |
mouse |
| Jing Zhao, Chanel J Taylor, Estella A Newcombe, Mark D Spanevello, Imogen O'Keeffe, Leanne T Cooper, Dhanisha J Jhaveri, Andrew W Boyd, Perry F Bartlet. EphA4 Regulates Hippocampal Neural Precursor Proliferation in the Adult Mouse Brain by d-Serine Modulation of N-Methyl-d-Aspartate Receptor Signaling. Cerebral cortex (New York, N.Y. : 1991). vol 29. issue 10. 2020-10-13. PMID:30590507. |
here, we show that, in the adult mouse brain, epha4 inhibits hippocampal precursor cell proliferation but does not affect precursor differentiation or survival. |
2020-10-13 |
2023-08-13 |
mouse |