| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Salahuddin Mohammad, Mélissa Gentreau, Manon Dubol, Gull Rukh, Jessica Mwinyi, Helgi B Schiöt. Association of polygenic scores for autism with volumetric MRI phenotypes in cerebellum and brainstem in adults. Molecular autism. vol 15. issue 1. 2024-08-08. PMID:39113134. |
asd prs were significantly associated with the volumes of seven brain areas, whereby higher prs were associated to reduced volumes of the whole brain, wm, brainstem, and cerebellar regions i-iv, ix, and x, and an increased volume of the csf. |
2024-08-08 |
2024-08-10 |
human |
| Jessica C Butts, Sih-Rong Wu, Mark A Durham, Ryan S Dhindsa, Jean-Pierre Revelli, M Cecilia Ljungberg, Olivier Saulnier, Madison E McLaren, Michael D Taylor, Huda Y Zoghb. A single-cell transcriptomic map of the developing Atoh1 lineage identifies neural fate decisions and neuronal diversity in the hindbrain. Developmental cell. 2024-08-06. PMID:39106860. |
one such transcription factor, atonal homolog 1 (atoh1), gives rise to cerebellar excitatory neurons and over 30 distinct nuclei in the brainstem critical for hearing, breathing, and balance. |
2024-08-06 |
2024-08-09 |
mouse |
| Nisha L Busch, Alejandro Matos Cruz, John Herbst, Kymberly Gyure, Rodney Wegner, Alexander Yu, Matthew J Shepar. Trigeminal nerve hemangioblastoma in the setting of undiagnosed von Hippel-Lindau disease: illustrative case. Journal of neurosurgery. Case lessons. vol 8. issue 5. 2024-07-29. PMID:39074390. |
patients with vhl are predisposed to developing numerous neoplasms, including central nervous system hemangioblastomas that typically arise within the cerebellum, brainstem, or spinal cord. |
2024-07-29 |
2024-08-02 |
Not clear |
| Sonali Mishra, Pamela Kell, David Scherrer, Dennis J Dietzen, Charles H Vite, Elizabeth Berry-Kravis, Cristin Davidson, Stephanie M Cologna, Forbes D Porter, Daniel S Ory, Xuntian Jian. Accumulation of Alkyl-lysophosphatidylcholines in Niemann-Pick Disease Type C1. Journal of lipid research. 2024-07-24. PMID:39048052. |
our findings unveiled a substantial elevation in the levels of three alkyl-lysophosphatidylcholine (alkyl-lpc, also known as lyso-platelet activating factor (lyso-paf)) species in npc1 compared to controls across various tissues, including brain tissue from individuals with npc1, liver, spleen, cerebrum, cerebellum, and brain stem from npc1 mice, as well as in both brain and liver tissue from npc1 cats. |
2024-07-24 |
2024-07-28 |
mouse |
| Qijun Li, Hang Li, Zhaoxia Huang, Yanfeng Li, Ruixue Cu. A Peculiar Tau Accumulation Pattern Identified Via 18F-Florzolotau PET Imaging in a Patient With Frontotemporal Dementia Caused by a Mutation in the MAPT Gene. Clinical nuclear medicine. 2024-07-16. PMID:39010313. |
18f-florzolotau pet showed tau proteins accumulated in medial temporal lobes, basal ganglia brainstem, and cerebellum. |
2024-07-16 |
2024-07-18 |
Not clear |
| Jason A Chen, Aaron E L Warren, John D Rolsto. Robot-assisted deep brain stimulation of the centromedian nucleus of the thalamus for generalized epilepsy: targeting and operative video. Neurosurgical focus: Video. vol 11. issue 1. 2024-07-03. PMID:38957429. |
cm is highly connected to cortical and subcortical regions including frontoparietal/sensorimotor cortex, striatum, brainstem, and cerebellum, which are involved in some generalized epilepsy syndromes like lennox-gastaut syndrome (lgs). |
2024-07-03 |
2024-07-06 |
Not clear |
| Yu Naruse, Mio Endo, Dai Uzuki, Kiyoshi Sait. Endoscopic Cerebellar Necrosectomy for Space-occupying Cerebellar Infarction: A Case Report. NMC case report journal. vol 11. 2024-06-24. PMID:38911925. |
suboccipital decompressive craniectomy with or without resection of necrosis is the preferred treatment for space-occupying cerebellar infarctions with neurological deterioration due to brainstem compression and obstructive hydrocephalus. |
2024-06-24 |
2024-06-26 |
Not clear |
| Joseph T Coyl. Passing the torch: The ascendance of the glutamatergic synapse in the pathophysiology of schizophrenia. Biochemical pharmacology. 2024-06-21. PMID:38906225. |
to function, the nmda receptor requires the binding of glycine (primarily in the cerebellum and brainstem) or d-serine (in forebrain) to the nr1 channel subunit of the nmda receptor. |
2024-06-21 |
2024-06-24 |
mouse |
| Marlene Tahedl, Ee Ling Tan, Jana Kleinerova, Siobhan Delaney, Jennifer C Hengeveld, Mark A Doherty, Russell L Mclaughlin, Pierre-Francois Pradat, Cédric Raoul, Fabrice Ango, Orla Hardiman, Kai Ming Chang, Jasmin Lope, Peter Bed. Progressive Cerebrocerebellar Uncoupling in Sporadic and Genetic Forms of Amyotrophic Lateral Sclerosis. Neurology. vol 103. issue 2. 2024-06-20. PMID:38900989. |
amyotrophic lateral sclerosis (als) is predominantly associated with motor cortex, corticospinal tract (cst), brainstem, and spinal cord degeneration, and cerebellar involvement is much less well characterized. |
2024-06-20 |
2024-06-23 |
Not clear |
| David H Gutman. Leveraging murine models of the neurofibromatosis type 1 cancer predisposition syndrome to elucidate the cellular circuits that drive pediatric low-grade glioma formation and progression. Neuro-oncology advances. vol 6. issue 1. 2024-06-10. PMID:38855054. |
as such, children with nf1 are at increased risk of developing lggs of the optic pathway, brainstem, cerebellum, and midline brain structures. |
2024-06-10 |
2024-06-14 |
mouse |
| René Labounek, Monica T Bondy, Amy L Paulson, Sandrine Bédard, Mihael Abramovic, Eva Alonso-Ortiz, Nicole T Atcheson, Laura R Barlow, Robert L Barry, Markus Barth, Marco Battiston, Christian Büchel, Matthew D Budde, Virginie Callot, Anna Combes, Benjamin De Leener, Maxime Descoteaux, Paulo Loureiro de Sousa, Marek Dostál, Julien Doyon, Adam V Dvorak, Falk Eippert, Karla R Epperson, Kevin S Epperson, Patrick Freund, Jürgen Finsterbusch, Alexandru Foias, Michela Fratini, Issei Fukunaga, Claudia A M Gandini Wheeler-Kingshott, GianCarlo Germani, Guillaume Gilbert, Federico Giove, Francesco Grussu, Akifumi Hagiwara, Pierre-Gilles Henry, Tomáš Horák, Masaaki Hori, James M Joers, Kouhei Kamiya, Haleh Karbasforoushan, Miloš Keřkovský, Ali Khatibi, Joo-Won Kim, Nawal Kinany, Hagen Kitzler, Shannon Kolind, Yazhuo Kong, Petr Kudlička, Paul Kuntke, Nyoman D Kurniawan, Slawomir Kusmia, Maria Marcella Laganà, Cornelia Laule, Christine S W Law, Tobias Leutritz, Yaou Liu, Sara Llufriu, Sean Mackey, Allan R Martin, Eloy Martinez-Heras, Loan Mattera, Kristin P O'Grady, Nico Papinutto, Daniel Papp, Deborah Pareto, Todd B Parrish, Anna Pichiecchio, Ferran Prados, Àlex Rovira, Marc J Ruitenberg, Rebecca S Samson, Giovanni Savini, Maryam Seif, Alan C Seifert, Alex K Smith, Seth A Smith, Zachary A Smith, Elisabeth Solana, Yuichi Suzuki, George W Tackley, Alexandra Tinnermann, Jan Valošek, Dimitri Van De Ville, Marios C Yiannakas, Kenneth A Weber, Nikolaus Weiskopf, Richard G Wise, Patrik O Wyss, Junqian Xu, Julien Cohen-Adad, Christophe Lenglet, Igor Nestraši. Body size interacts with the structure of the central nervous system: A multi-center in vivo neuroimaging study. bioRxiv : the preprint server for biology. 2024-05-24. PMID:38746371. |
we show that body height correlated strongly or moderately with brain gray matter (gm) volume, cortical gm volume, total cerebellar volume, brainstem volume, and cross-sectional area (csa) of cervical sc white matter (csa-wm; 0.44≤r≤0.62). |
2024-05-24 |
2024-05-27 |
human |
| Limei Song, Yun Peng, Minhui Ouyang, Qinmu Peng, Lei Feng, Susan Sotardi, Qinlin Yu, Huiying Kang, Kay L Sindabizera, Shuwei Liu, Hao Huan. Diffusion-tensor-imaging 1-year-old and 2-year-old infant brain atlases with comprehensive gray and white matter labels. Human brain mapping. vol 45. issue 7. 2024-05-10. PMID:38727010. |
each age-specific atlas consists of 124 comprehensively labeled major gm and wm structures, including 52 cerebral cortical, 10 deep gm, 40 wm, and 22 brainstem and cerebellar structures. |
2024-05-10 |
2024-05-27 |
human |
| Miaomiao Yin, Liling Cui, Yue Zhan. Vestibular Rehabilitation of Patient with Hypertrophic Olivary Degeneration: A Case Report. Journal of the American Academy of Audiology. 2024-05-06. PMID:38710219. |
background hypertrophic olivary degeneration (hod) is a rare disorder that typically develops in the weeks to months following a structural brainstem or cerebellar lesion in the guillain-mollaret triangle (gmt). |
2024-05-06 |
2024-05-27 |
Not clear |
| Francesca Orlandi, Arenn F Carlos, Farwa Ali, Heather M Clark, Joseph R Duffy, Rene L Utianski, Hugo Botha, Mary M Machulda, Yehkyoung C Stephens, Christopher G Schwarz, Matthew L Senjem, Clifford R Jack, Federica Agosta, Massimo Filippi, Dennis W Dickson, Keith A Josephs, Jennifer L Whitwel. Histologic tau lesions and magnetic resonance imaging biomarkers differ across two progressive supranuclear palsy variants. Brain communications. vol 6. issue 2. 2024-04-26. PMID:38660629. |
progressive supranuclear palsy is a neurodegenerative disease characterized by the deposition of four-repeat tau in neuronal and glial lesions in the brainstem, cerebellar, subcortical and cortical brain regions. |
2024-04-26 |
2024-04-28 |
Not clear |
| Olga S Belozor, Alex Vasilev, Alexandra G Mileiko, Lyudmila D Mosina, Ilya G Mikhailov, Darius A Ox, Elizaveta B Boitsova, Andrey N Shuvaev, Anja G Teschemacher, Sergey Kasparov, Anton N Shuvae. Memantine suppresses the excitotoxicity but fails to rescue the ataxic phenotype in SCA1 model mice. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 174. 2024-04-04. PMID:38574621. |
spinocerebellar ataxia type 1 (sca1) is a debilitating neurodegenerative disorder of the cerebellum and brainstem. |
2024-04-04 |
2024-04-07 |
mouse |
| Ricardo De Miguel, Devon Wallis Hague, Jennifer L Johnson, Amber M Zilinger, Anna Kukekova, Stephane Lezm. Congenital spongiform leukodystrophy in 2 female littermate German shepherd puppies. Journal of veterinary internal medicine. 2024-03-28. PMID:38544400. |
the white matter (wm) of the central nervous system (cns) showed bilateral diffuse severe spongiosis in the cerebellum, brainstem, spinal cord, and the neuropil of the oculomotor and red nuclei. |
2024-03-28 |
2024-03-30 |
Not clear |
| Jarek Wegiel, Kathryn Chadman, Eric London, Thomas Wisniewski, Jerzy Wegie. Contribution of the serotonergic system to developmental brain abnormalities in autism spectrum disorder. Autism research : official journal of the International Society for Autism Research. 2024-03-19. PMID:38500252. |
this review highlights a key role of the serotonergic system in brain development and in distortions of normal brain development in early stages of fetal life resulting in cascades of abnormalities, including defects of neurogenesis, neuronal migration, neuronal growth, differentiation, and arborization, as well as defective neuronal circuit formation in the cortex, subcortical structures, brainstem, and cerebellum of autistic subjects. |
2024-03-19 |
2024-03-21 |
human |
| Roberta De Mori, Silvia Tardivo, Lidia Pollara, Silvia Clara Giliani, Eltahir Ali, Lucio Giordano, Vincenzo Leuzzi, Rita Fischetto, Blanca Gener, Santo Diprima, Marco J Morelli, Maria Cristina Monti, Virginie Sottile, Enza Maria Valent. Joubert syndrome-derived induced pluripotent stem cells show altered neuronal differentiation in vitro. Cell and tissue research. 2024-03-19. PMID:38502237. |
joubert syndrome (js) is a recessively inherited congenital ataxia characterized by hypotonia, psychomotor delay, abnormal ocular movements, intellectual disability, and a peculiar cerebellar and brainstem malformation, the "molar tooth sign." |
2024-03-19 |
2024-03-23 |
Not clear |
| Jane E Persons, Stephanie Stauffe. Fatal Vertebral Artery Dissection Following Self-Manipulation of the Cervical Spine. The American journal of forensic medicine and pathology. 2024-03-18. PMID:38497612. |
death was attributed to self-manipulation of the neck, which in turn led to bilateral vertebral artery dissection, cerebellar and brainstem infarcts, herniation, hypoxic-ischemic injury, and ultimately brain death. |
2024-03-18 |
2024-03-20 |
Not clear |
| Xiaolong Wang, Lixiong Xue, Li Han, Xinmin Din. End-to-end revascularization between the occipital Artery(OA) and the p1 segment of posterior inferior cerebellar Artery(PICA) for a patient with posterior circulation ischemia via a far-lateral approach:2-Dimensional Operative video. World neurosurgery: X. vol 22. 2024-03-06. PMID:38444871. |
vertebral artery （va）aneurysms involving the origin of the posterior inferior cerebellar artery (pica) ,occasionally, induce cerebellum and brainstem infarction due to intraluminal thrombus and calcific va stenosis. |
2024-03-06 |
2024-03-08 |
Not clear |