| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mikhail Matveyenka, Abid Ali, Charles L Mitchell, Harris C Brown, Dmitry Kurousk. Cholesterol Accelerates Aggregation of α-Synuclein Simultaneously Increasing the Toxicity of Amyloid Fibrils. ACS chemical neuroscience. 2024-10-29. PMID:39469734. |
a hallmark of parkinson disease (pd) is a progressive degeneration of neurons in the substantia nigra pars compacta, hypothalamus, and thalamus. |
2024-10-29 |
2024-10-31 |
Not clear |
| Kiryl Zhaliazka, Abid Ali, Dmitry Kurousk. Phospholipids and Cholesterol Determine Molecular Mechanisms of Cytotoxicity of α-Synuclein Oligomers and Fibrils. ACS chemical neuroscience. 2024-01-03. PMID:38166409. |
progressive loss of dopaminergic (da) neurons in the substantia nigra pars compacta, hypothalamus, and thalamus is a hallmark of parkinson's disease. |
2024-01-03 |
2024-01-10 |
rat |
| M Y Lee, S H Choi, S L Shin, H Chin, O J Kwo. Distribution of B/K protein in rat brain. Cell and tissue research. vol 303. issue 1. 2001-03-29. PMID:11236004. |
immunoreactivity to b/k protein was widely found in distinct regions of rat brain: strongly in the hypothalamus, most of the circumventricular organs, the locus coeruleus, the a5 neurons of the pons, and the anterior pituitary; moderately in the anterior olfactory nucleus, the raphe nucleus, the subfornical organ, and the median eminence; and faintly in the olfactory bulb, the telencephalon, the substantia nigra pars compacta, and the ventral tegmental area. |
2001-03-29 |
2023-08-12 |
rat |
| D O'Donnell, S Ahmad, C Wahlestedt, P Walke. Expression of the novel galanin receptor subtype GALR2 in the adult rat CNS: distinct distribution from GALR1. The Journal of comparative neurology. vol 409. issue 3. 1999-07-28. PMID:10379831. |
moderate levels of galr2 mrna are observed in the olfactory bulb, olfactory tubercle, piriform and retrospinal cortices, hypothalamus (namely the preoptic area, arcuate nucleus, and dorsal hypothalamic area), substantia nigra pars compacta, and sensory trigeminal nucleus. |
1999-07-28 |
2023-08-12 |
rat |
| S I Lentz, G Kapato. Tetrahydrobiopterin biosynthesis in the rat brain: heterogeneity of GTP cyclohydrolase I mRNA expression in monoamine-containing neurons. Neurochemistry international. vol 28. issue 5-6. 1996-12-30. PMID:8792338. |
comparisons across dopamine cell groups indicated that the transcript was more abundant in neurons of the ventral tegmental area (a10) than in neurons of the substantia nigra pars compacta (a9) and that both a9 and a10 dopamine neurons exhibited higher levels of expression than the da neurons of the hypothalamus (a11-a14). |
1996-12-30 |
2023-08-12 |
rat |
| N A Seniuk, W G Tatton, C E Greenwoo. Dose-dependent destruction of the coeruleus-cortical and nigral-striatal projections by MPTP. Brain research. vol 527. issue 1. 1991-03-19. PMID:1980841. |
in order to determine whether 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) produces neuronal death or the loss of tyrosine hydroxylase (th) immunoreactivity, 4 catecholaminergic nuclei in the mouse: substantia nigra compacta (snc), locus coeruleus (lc), ventral tegmental area (vta) and the a13 nucleus in the hypothalamus were quantitatively examined. |
1991-03-19 |
2023-08-11 |
mouse |
| R Kim, K Nakano, A Jayaraman, M B Carpente. Projections of the globus pallidus and adjacent structures: an autoradiographic study in the monkey. The Journal of comparative neurology. vol 169. issue 3. 1976-12-03. PMID:823180. |
cells in sublenticular portions of si, and those extending into the medullary laminae of the pallidum, appear to project to: (1) hb1 via the stria medullaris, (2) the pars compacta of sn, (3) lateral and posterior regions of the hypothalamus, and (4) the so-called nucleus of the ansa lenticularis. |
1976-12-03 |
2023-08-11 |
monkey |