| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Elena Predescu, Tudor Vaidean, Andreea-Marlena Rapciuc, Roxana Sipo. Metabolomic Markers in Attention-Deficit/Hyperactivity Disorder (ADHD) among Children and Adolescents-A Systematic Review. International journal of molecular sciences. vol 25. issue 8. 2024-04-27. PMID:38673970. |
synthesis revealed intricate links between adhd and altered amino acid metabolism, neurotransmitter dysregulation (especially dopamine and serotonin), oxidative stress, and the kynurenine pathway impacting neurotransmitter homeostasis. |
2024-04-27 |
2024-04-29 |
human |
| Chen-Lei Wu, Meng-Fei Wang, Rong-Yi Zho. [Recent research on the role of oxidative stress in the pathogenesis of attention deficit hyperactivity disorder]. Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics. vol 26. issue 2. 2024-03-04. PMID:38436320. |
based on the latest research findings in china and overseas, this article reviews the clinical and experimental studies on oxidative stress in adhd and explores the association of oxidative stress with neurotransmitter imbalance, neuroinflammation, and cell apoptosis in the pathogenesis of adhd, so as to provide new research ideas for exploring the pathogenesis of adhd. |
2024-03-04 |
2024-03-06 |
human |
| Giulia Spoto, Gabriella Di Rosa, Antonio Gennaro Nicoter. The Impact of Genetics on Cognition: Insights into Cognitive Disorders and Single Nucleotide Polymorphisms. Journal of personalized medicine. vol 14. issue 2. 2024-02-23. PMID:38392589. |
focusing on neurotransmitter regulation within the prefrontal cortex's dopaminergic circuits, this study emphasizes the role of genes like comt, prodh, and drd in shaping executive functions and influencing conditions such as adhd and schizophrenia. |
2024-02-23 |
2024-02-25 |
Not clear |
| Won-Seok Lee, Bo-Eun Yoo. Necessity of an Integrative Animal Model for a Comprehensive Study of Attention-Deficit/Hyperactivity Disorder. Biomedicines. vol 11. issue 5. 2023-05-27. PMID:37238931. |
these models allow researchers to conduct controlled experiments and manipulate specific brain regions or neurotransmitter systems to investigate the underlying causes of adhd and test potential drug targets or treatments. |
2023-05-27 |
2023-08-14 |
Not clear |
| Daniela Vázquez-González, Sonia Carreón-Trujillo, Lourdes Alvarez-Arellano, Daniela Melissa Abarca-Merlin, Pablo Domínguez-López, Marcela Salazar-García, Juan Carlos Coron. A Potential Role for Neuroinflammation in ADHD. Advances in experimental medicine and biology. vol 1411. 2023-03-23. PMID:36949317. |
although increases in oxidative stress and disturbances of neurotransmitter system such as the dopaminergic and abnormalities in several brain regions have been demonstrated, the pathophysiology of adhd is not fully understood. |
2023-03-23 |
2023-08-14 |
Not clear |
| Gustavo Sudre, Derek E Gildea, Gauri G Shastri, Wendy Sharp, Benjamin Jung, Qing Xu, Pavan K Auluck, Laura Elnitski, Andreas D Baxevanis, Stefano Marenco, Philip Sha. Mapping the cortico-striatal transcriptome in attention deficit hyperactivity disorder. Molecular psychiatry. 2022-11-15. PMID:36380233. |
significant downregulation emerged of neurotransmitter gene pathways, particularly glutamatergic, in keeping with models that implicate these neurotransmitters in adhd. |
2022-11-15 |
2023-08-14 |
Not clear |
| Gustavo Sudre, Derek E Gildea, Gauri G Shastri, Wendy Sharp, Benjamin Jung, Qing Xu, Pavan K Auluck, Laura Elnitski, Andreas D Baxevanis, Stefano Marenco, Philip Sha. Mapping the cortico-striatal transcriptome in attention deficit hyperactivity disorder. Molecular psychiatry. 2022-11-15. PMID:36380233. |
this transcriptomic evidence points to cortico-striatal neurotransmitter anomalies in the pathogenesis of adhd, consistent with current models of the disorder. |
2022-11-15 |
2023-08-14 |
Not clear |
| Md Mominur Rahman, Md Rezaul Islam, Sadia Afsana Mim, Nasrin Sultana, Dinesh Kumar Chellappan, Kamal Dua, Mohammad Amjad Kamal, Rohit Sharma, Talha Bin Emra. Insights into the Promising Prospect of G Protein and GPCR-Mediated Signaling in Neuropathophysiology and Its Therapeutic Regulation. Oxidative medicine and cellular longevity. vol 2022. 2022-10-03. PMID:36187336. |
dopamine, an important neurotransmitter, is primarily involved in the pathophysiology of several cns disorders; for instance, bipolar disorder, schizophrenia, parkinson's disease, and adhd. |
2022-10-03 |
2023-08-14 |
Not clear |
| Natalia Kurzina, Anastasia Belskaya, Arina Gromova, Alla Ignashchenkova, Raul R Gainetdinov, Anna Volnov. Modulation of Spatial Memory Deficit and Hyperactivity in Dopamine Transporter Knockout Rats Frontiers in psychiatry. vol 13. 2022-04-11. PMID:35401264. |
the dopamine neurotransmitter system is postulated to be involved in the pathogenesis of adhd. |
2022-04-11 |
2023-08-13 |
rat |
| Ameanté Payen, Michelle J Chen, T Grace Carter, Ryan P Kilmer, Jeanette M Bennet. Childhood ADHD, Going Beyond the Brain: A Meta-Analysis on Peripheral Physiological Markers of the Heart and the Gut. Frontiers in endocrinology. vol 13. 2022-03-18. PMID:35299964. |
the dopaminergic neurotransmitter system, known for its influence on reward-motivated behaviors and motor control, and the frontostriatal systems, that mediate motor, cognition, and behavior, are associated with adhd's development. |
2022-03-18 |
2023-08-13 |
Not clear |
| Gerry Leisman, Dana Sheldo. Tics and Emotions. Brain sciences. vol 12. issue 2. 2022-02-25. PMID:35204005. |
dopamine plays a vital role in cognition and motor control and is an important neurotransmitter in the pathophysiology of other disorders such as obsessive-compulsive disorder (ocd) and attention deficit hyperactivity disorder (adhd), which tend to be comorbid with ticking disorders and are thought to use similar pathways. |
2022-02-25 |
2023-08-13 |
Not clear |
| Lin Zhang, Cathy Levenson, Valentina Cea Salazar, Joseph Biederman, Ross D Zafonte, Pradeep G Bhid. Repetitive mild traumatic brain injury in an awake, unanesthetized mouse model of perinatal nicotine exposure produces transient novelty-seeking and depression-like behaviors. Journal of neurotrauma. 2021-12-16. PMID:34913733. |
we used a mouse model of perinatal nicotine exposure (pne), which displays behavioral, neuroanatomical and neurotransmitter features consistent with adhd and subjected it to repetitive mtbi. |
2021-12-16 |
2023-08-13 |
mouse |
| Selina Cannon Homaei, Helene Barone, Rune Kleppe, Nibal Betari, Andreas Reif, Jan Haavi. ADHD symptoms in neurometabolic diseases: Underlying mechanisms and clinical implications. Neuroscience and biobehavioral reviews. 2021-11-23. PMID:34774900. |
we cite emerging evidence that many nmds converge on common neurochemical mechanisms that interfere with monoamine neurotransmitter synthesis, transport, metabolism, or receptor functions, mechanisms that are also considered central in adhd pathophysiology and treatment. |
2021-11-23 |
2023-08-13 |
Not clear |
| Yanni Wang, Tingwei Wang, Yukai Du, Dan Hu, Yu Zhang, Honghui Li, Wenyan Pe. Polygenic risk of genes involved in the catecholamine and serotonin pathways for ADHD in children. Neuroscience letters. vol 760. 2021-08-17. PMID:34174344. |
a pathway-based study was conducted in this study to test the association of gene-gene interaction and the cumulative effect of genetic polymorphisms within the dopamine, norepinephrine, and serotonin neurotransmitter pathways with adhd susceptibility. |
2021-08-17 |
2023-08-13 |
Not clear |
| Heike Weber, Sarah Kittel-Schneider, Julia Heupel, Lena Weißflog, Lindsey Kent, Florian Freudenberg, Aet Alttoa, Antonia Post, Sabine Herterich, Jan Haavik, Anne Halmøy, Ole B Fasmer, Elisabeth T Landaas, Stefan Johansson, Bru Cormand, Marta Ribasés, Cristina Sánchez-Mora, Josep Antoni Ramos-Quiroga, Barbara Franke, Klaus-Peter Lesch, Andreas Rei. On the role of NOS1 ex1f-VNTR in ADHD-allelic, subgroup, and meta-analysis. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 168. issue 6. 2020-09-30. PMID:26086921. |
several studies suggest that nos1, encoding nitric oxide synthase i, producing the gaseous neurotransmitter no, is a candidate gene for (adult) adhd. |
2020-09-30 |
2023-08-13 |
human |
| Frances M Nilsen, Nicolle S Tulv. A systematic review and meta-analysis examining the interrelationships between chemical and non-chemical stressors and inherent characteristics in children with ADHD. Environmental research. vol 180. 2020-09-09. PMID:31706600. |
adhd is characterized by developmentally inappropriate levels of hyperactivity, impulsivity, and inattention, with the neurotransmitter serotonin regulating these symptoms. |
2020-09-09 |
2023-08-13 |
Not clear |
| Stephanie Bull-Larsen, M Hasan Mohajer. The Potential Influence of the Bacterial Microbiome on the Development and Progression of ADHD. Nutrients. vol 11. issue 11. 2020-06-04. PMID:31744191. |
we reviewed the effect of a differing microbial makeup on neurotransmitter concentrations important in the pathophysiology of adhd. |
2020-06-04 |
2023-08-13 |
Not clear |
| Geoffrey A Dunn, Joel T Nigg, Elinor L Sulliva. Neuroinflammation as a risk factor for attention deficit hyperactivity disorder. Pharmacology, biochemistry, and behavior. vol 182. 2020-02-25. PMID:31103523. |
alterations in neurotransmitter systems, including the dopaminergic, serotonergic and glutamatergic systems, are observed in adhd populations. |
2020-02-25 |
2023-08-13 |
human |
| Priyanka Purkayastha, Aruna Malapati, Perumal Yogeeswari, Dharmarajan Srira. A Review on GABA/Glutamate Pathway for Therapeutic Intervention of ASD and ADHD Current medicinal chemistry. vol 22. issue 15. 2019-11-20. PMID:25666800. |
a review on gaba/glutamate pathway for therapeutic intervention of asd and adhd balance between excitatory glutamate and inhibitory gaba neurotransmitter is essential and critical for proper development and functioning of brain. |
2019-11-20 |
2023-08-13 |
Not clear |
| Andre Chevrier, Mehereen Bhaijiwala, Jonathan Lipszyc, Douglas Cheyne, Simon Graham, Russell Schacha. Disrupted reinforcement learning during post-error slowing in ADHD. PloS one. vol 14. issue 2. 2019-10-29. PMID:30785885. |
in adhd, results are consistent with heightened activities in the amygdala and non-dopaminergic neurotransmitter nuclei preventing reinforcement learning. |
2019-10-29 |
2023-08-13 |
Not clear |