| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chiara Lanzillotta, Monika Rataj Baniowska, Francesca Prestia, Chiara Sette, Valérie Nalesso, Marzia Perluigi, Eugenio Barone, Arnaud Duchon, Antonella Tramutola, Yann Herault, Fabio Di Domenic. Shaping down syndrome brain cognitive and molecular changes due to aging using adult animals from the Ts66Yah murine model. Neurobiology of disease. 2024-05-05. PMID:38705491. |
down syndrome (ds) is the most common condition with intellectual disability and is caused by trisomy of homo sapiens chromosome 21 (hsa21). |
2024-05-05 |
2024-05-08 |
mouse |
| S Hossein Fatemi, Elysabeth D Otte, Timothy D Folsom, Arthur C Eschenlauer, Randall J Roper, Justin W Aman, Paul D Thura. Early Chronic Fluoxetine Treatment of Ts65Dn Mice Rescues Synaptic Vesicular Deficits and Prevents Aberrant Proteomic Alterations. Genes. vol 15. issue 4. 2024-04-27. PMID:38674386. |
down syndrome (ds) is the most common form of inherited intellectual disability caused by trisomy of chromosome 21, presenting with intellectual impairment, craniofacial abnormalities, cardiac defects, and gastrointestinal disorders. |
2024-04-27 |
2024-04-29 |
mouse |
| Silvia Molinari, Chiara Fossati, Maria Laura Nicolosi, Santo Di Marco, Martha Caterina Faraguna, Francesca Limido, Laura Ocello, Claudia Pellegrinelli, Martina Lattuada, Alessandra Gazzarri, Alessandra Lazzerotti, Debora Sala, Chiara Vimercati, Giulia Capitoli, Cecilia Daolio, Andrea Biondi, Adriana Balduzzi, Alessandro Catton. Endocrine, auxological and metabolic profile in children and adolescents with Down syndrome: from infancy to the first steps into adult life. Frontiers in endocrinology. vol 15. 2024-04-24. PMID:38654931. |
along with intellectual disability, endocrine disorders represent a remarkable share of the morbidities experienced by children, adolescents and young adults with ds. |
2024-04-24 |
2024-04-28 |
Not clear |
| Zuolin Zhou, Yanhua Bi, Chunchun Zhi, Siqi Chen, Die Chen, Zhen Wei, Xiaoling Jian. Astroglial activation is exacerbated in a Down syndrome mouse model. Neuroscience. 2024-04-14. PMID:38615829. |
down syndrome (ds), also known as trisomy 21, is one of the most common chromosomal disorders associated with intellectual disability. |
2024-04-14 |
2024-04-17 |
mouse |
| Zuolin Zhou, Yanhua Bi, Chunchun Zhi, Siqi Chen, Die Chen, Zhen Wei, Xiaoling Jian. Astroglial activation is exacerbated in a Down syndrome mouse model. Neuroscience. 2024-04-14. PMID:38615829. |
the inflammatory response of astrocytes might be a potential therapeutic target for ds intellectual disability. |
2024-04-14 |
2024-04-17 |
mouse |
| Ken Pitetti, Fabio Bertapelli, Ruth A Miller, Adam Jaeger, E Michael Loovis, Wilson D do Amaral-Junior, Marcos M de Barros-Filho, Gil Guerra-Junio. Homogeneity in Motor Competence Among Youths With Intellectual Disability With and Without Down Syndrome. Pediatric physical therapy : the official publication of the Section on Pediatrics of the American Physical Therapy Association. vol 36. issue 2. 2024-04-03. PMID:38568273. |
to determine if there is a homogeneity of scores for youth with intellectual disability (id) with and without down syndrome (ds) in 19 test items of motor competence from the bruininks-oseretsky test of motor proficiency-second edition (bot-2). |
2024-04-03 |
2024-04-05 |
Not clear |
| Amber Postma, Crista A Minderhoud, Wim M Otte, Floor E Jansen, W B Gunning, Judith S Verhoeven, Marian J Jongmans, Janneke R Zinkstok, Eva H Brilstr. Understanding neurodevelopmental trajectories and behavioral profiles in SCN1A-related epilepsy syndromes. Epilepsy & behavior : E&B. vol 154. 2024-03-21. PMID:38513571. |
dravet syndrome (ds) is associated with refractory seizures, developmental delay, intellectual disability (id), motor impairment, and challenging behavior(1,2). |
2024-03-21 |
2024-03-24 |
Not clear |
| Alessio Faralli, Elisa Fucà, Giulia Lazzaro, Deny Menghini, Stefano Vicari, Floriana Costanz. Transcranial Direct Current Stimulation in neurogenetic syndromes: new treatment perspectives for Down syndrome? Frontiers in cellular neuroscience. vol 18. 2024-03-08. PMID:38456063. |
this perspective review aims to explore the potential neurobiological mechanisms involved in the application of transcranial direct current stimulation (tdcs) for down syndrome (ds), the leading cause of genetically-based intellectual disability. |
2024-03-08 |
2024-03-10 |
Not clear |
| Alexandra DiFilippo, Erin Jonaitis, Renee Makuch, Brianna Gambetti, Victoria Fleming, Gilda Ennis, Todd Barnhart, Jonathan Engle, Barbara Bendlin, Sterling Johnson, Benjamin Handen, Sharon Krinsky-McHale, Sigan Hartley, Bradley Christia. Measurement of synaptic density in Down syndrome using PET imaging: a pilot study. Scientific reports. vol 14. issue 1. 2024-02-28. PMID:38409349. |
down syndrome (ds) is the most prevalent genetic cause of intellectual disability, resulting from trisomy 21. |
2024-02-28 |
2024-03-01 |
Not clear |
| Cesar Sierra, Miguel Sabariego-Navarro, Álvaro Fernández-Blanco, Sonia Cruciani, Alfonsa Zamora-Moratalla, Eva Maria Novoa, Mara Diersse. The lncRNA Snhg11, a new candidate contributing to neurogenesis, plasticity, and memory deficits in Down syndrome. Molecular psychiatry. 2024-02-27. PMID:38409595. |
down syndrome (ds) stands as the prevalent genetic cause of intellectual disability, yet comprehensive understanding of its cellular and molecular underpinnings remains limited. |
2024-02-27 |
2024-03-02 |
mouse |
| Carolina Gastelum Guerrero, Yuridia Lizet Cháidez Fernández, Dalia Magaña Ordorica, Heidi Berger, Marilyn Vazquez Landrove, Alma Guadrón Llanos, Carla Angulo Rojo, Javier Magaña Góme. A systematic review and meta-analysis of serum lipid concentrations in people with Down syndrome. Journal of intellectual disability research : JIDR. 2024-02-26. PMID:38404114. |
down syndrome (ds) is the most prevalent chromosomal disorder, being the leading cause of intellectual disability. |
2024-02-26 |
2024-02-28 |
Not clear |
| Miren Altuna, Ainara Estanga, Adolfo Garrido, Jon Saldias, Marta Cañada, Maitane Echeverria, José Ángel Larrea, Patricia Ayo, Ainhoa Fiz, María Muñoz, José Santa-Inés, Valeria García-Landarte, Maite García-Sebastiá. Down Syndrome-Basque Alzheimer Initiative (DS-BAI): Clinic-Biological Cohort. Journal of clinical medicine. vol 13. issue 4. 2024-02-24. PMID:38398452. |
down syndrome (ds) is the most common genetically determined intellectual disability. |
2024-02-24 |
2024-02-26 |
Not clear |
| Maysoun Kudsi, Diaa Haj Ali, Naram Khalayli, Samah Jaber, Rama Nasser Mansour Almasr. Systemic lupus erythematosus and Down syndrome: a case report and literature review. Annals of medicine and surgery (2012). vol 86. issue 2. 2024-02-09. PMID:38333242. |
down syndrome (ds) is the most frequent genetic cause of intellectual disabilities, typically caused by the presence of an extra chromosome 21. |
2024-02-09 |
2024-02-11 |
Not clear |
| Eliza Gaweł, Diana Celebańska, Anna Zwierzchowsk. Differentiation of the body build and posture in the population of people with intellectual disabilities and Down Syndrome: a systematic review. BMC public health. vol 24. issue 1. 2024-02-07. PMID:38326795. |
the aim of the study was to identify the variables of the internal compensatory mechanisms that differentiate the body build and posture of people with down syndrome (ds) from the intellectual disability (id) population. |
2024-02-07 |
2024-02-10 |
Not clear |
| Maria Elisa Serrano, Eugene Kim, Bernard Siow, Da Ma, Loreto Rojo, Camilla Simmons, Darryl Hayward, Dorota Gibbins, Nisha Singh, Andre Strydom, Elizabeth M C Fisher, Victor L J Tybulewicz, Diana Cas. Investigating brain alterations in the Dp1Tyb mouse model of Down syndrome. Neurobiology of disease. vol 188. 2024-02-06. PMID:38317803. |
down syndrome (ds) is one of the most common birth defects and the most prevalent genetic form of intellectual disability. |
2024-02-06 |
2024-02-09 |
mouse |
| Rosa López-Hidalgo, Raúl Ballestín, Lorena Lorenzo, Sandra Sánchez, José Miguel Blasco-Ibáñez, Carlos Crespo, Juan Nacher, Emilio Vare. Early chronic fasudil treatment rescues hippocampal alterations in the Ts65Dn model for down syndrome. Neurochemistry international. 2024-02-03. PMID:38309665. |
down syndrome (ds) is the most common genetic disorder associated with intellectual disability. |
2024-02-03 |
2024-02-06 |
mouse |
| Eri Shimizu, Keiko Goto-Hirano, Yumiko Motoi, Masami Arai, Nobutaka Hattor. Symptoms and age of prodromal Alzheimer's disease in Down syndrome: a systematic review and meta-analysis. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. 2024-01-16. PMID:38228941. |
this study investigated the specific symptoms of ad in the prodromal stage of ds, the mean age at diagnosis at each stage of dementia, and the relationship between intellectual disability (id) and dementia. |
2024-01-16 |
2024-01-19 |
Not clear |
| Nesreen Safwat El Feil, Heba S Elmahdy, Rasha Ahmed Elmahdy, Ahmed Abd-Elbasset Aboelezz, Heba S Dawoud, Mohammed Al-Beltag. Brain metabolic profile assessed by magnetic resonance spectroscopy in children with Down syndrome: Relation to intelligence quotient. World journal of clinical pediatrics. vol 12. issue 5. 2024-01-05. PMID:38178937. |
down syndrome (ds) is one of the most common causes of intellectual disability. |
2024-01-05 |
2024-01-07 |
Not clear |
| John K Mich, Jiyun Ryu, Aguan D Wei, Bryan B Gore, Rong Guo, Angela M Bard, Refugio A Martinez, Yemeserach Bishaw, Em Luber, Luiz M Oliveira Santos, Nicole Miranda, Jan-Marino Ramirez, Jonathan T Ting, Ed S Lein, Boaz P Levi, Franck K Kalum. AAV-mediated interneuron-specific gene replacement for Dravet syndrome. bioRxiv : the preprint server for biology. 2024-01-03. PMID:38168178. |
dravet syndrome (ds) is a devastating developmental epileptic encephalopathy marked by treatment-resistant seizures, developmental delay, intellectual disability, motor deficits, and a 10-20% rate of premature death. |
2024-01-03 |
2024-01-06 |
Not clear |
| Anna Rozensztrauch, Karolina Wieczorek, Iwona Twardak, Robert Śmigie. Health-related quality of life and family functioning of primary caregivers of children with down syndrome. Frontiers in psychiatry. vol 14. 2024-01-01. PMID:38161724. |
down syndrome (ds; omim #190685), known as trisomy 21, is one of the most common genetic disorders in the human population and the commonest known cause of intellectual disability. |
2024-01-01 |
2024-01-05 |
human |