All Relations between Muscle Weakness and Myotoxicity
Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Mingqiang Ren, Nyamkhishig Sambuughin, Ognoon Mungunshukh, Daniel Baxter Edgeworth, Daniel Hupalo, Xijun Zhang, Matthew D Wilkerson, Clifton L Dalgard, Francis G O'Connor, Patricia A Deuste. Genome-Wide Analysis of Exertional Rhabdomyolysis in Sickle Cell Trait Positive African Americans. Genes. vol 15. issue 4. 2024-04-27. PMID:38674343. |
sct carriers with erm were characterized by myotoxicity features, significant muscle involvement dominated by muscle weakness, and severe pain and substantial increase in serum creatine kinase, with a mean value of 50,480 u/l. |
2024-04-27 |
2024-04-29 |
human |
Payam Mohassel, Andrew L Mamme. Statin-associated autoimmune myopathy and anti-HMGCR autoantibodies. Muscle & nerve. vol 48. issue 4. 2013-11-29. PMID:23519993. |
although statin myotoxicity is usually self-limited, in some instances statin-exposed subjects can develop an autoimmune myopathy typically characterized by progressive weakness, muscle enzyme elevations, a necrotizing myopathy on muscle biopsy, and autoantibodies that recognize 3-hydroxy-3-methylglutaryl-coenzyme a reductase (hmgcr), the pharmacologic target of statins. |
2013-11-29 |
2023-08-12 |
human |