All Relations between Optic Neuritis and cfh
| Publication | Sentence | Publish Date | Extraction Date | Species |
|---|---|---|---|---|
| Sheri L Peterson, Anitha Krishnan, Diyan Patel, Ali Khanehzar, Amit Lad, Jutamas Shaughnessy, Sanjay Ram, David Callanan, Derek Kunimoto, Mohamed A Genead, Michael J Tolentin. PolySialic Acid Nanoparticles Actuate Complement-Factor-H-Mediated Inhibition of the Alternative Complement Pathway: A Safer Potential Therapy for Age-Related Macular Degeneration. Pharmaceuticals (Basel, Switzerland). vol 17. issue 4. 2024-04-27. PMID:38675477. | complement depletion with pegcetacoplan and avacincaptad pegol are fda-approved treatments for geographic atrophy in amd that, while effective, have clinically observed risks of choroidal neovascular (cnv) conversion, optic neuritis, and retinal vasculitis, leaving room for other equally efficacious but safer therapeutics, including poly sialic acid (psa) nanoparticle (polysia-np)-actuated complement factor h (cfh) alternative pathway inhibition. | 2024-04-27 | 2024-04-29 | mouse |