| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Gergely Keszler, Bálint Vékony, Zsuzsanna Elek, Zsófia Nemoda, Nóra Angyal, Zsófia Bánlaki, Réka Kovács-Nagy, Zsolt Rónai, János M Réthely. MicroRNA-Mediated Suppression of Glial Cell Line-Derived Neurotrophic Factor Expression Is Modulated by a Schizophrenia-Associated Non-Coding Polymorphism. International journal of molecular sciences. vol 25. issue 8. 2024-04-27. PMID:38674063. |
to explore the involvement of gdnf in the pathogenesis of the disease, a case-control association analysis was performed between five non-coding single nucleotide polymorphisms (snp) across the gdnf gene and schizophrenia. |
2024-04-27 |
2024-04-29 |
human |
| Gergely Keszler, Bálint Vékony, Zsuzsanna Elek, Zsófia Nemoda, Nóra Angyal, Zsófia Bánlaki, Réka Kovács-Nagy, Zsolt Rónai, János M Réthely. MicroRNA-Mediated Suppression of Glial Cell Line-Derived Neurotrophic Factor Expression Is Modulated by a Schizophrenia-Associated Non-Coding Polymorphism. International journal of molecular sciences. vol 25. issue 8. 2024-04-27. PMID:38674063. |
our results imply that the rs11111 'g' allele occurring more frequently in patients with schizophrenia might downregulate gdnf expression in a mirna-dependent fashion. |
2024-04-27 |
2024-04-29 |
human |
| Gergely Keszler, Bálint Vékony, Zsuzsanna Elek, Zsófia Nemoda, Nóra Angyal, Zsófia Bánlaki, Réka Kovács-Nagy, Zsolt Rónai, János M Réthely. MicroRNA-Mediated Suppression of Glial Cell Line-Derived Neurotrophic Factor Expression Is Modulated by a Schizophrenia-Associated Non-Coding Polymorphism. International journal of molecular sciences. vol 25. issue 8. 2024-04-27. PMID:38674063. |
plasma levels of glial cell line-derived neurotrophic factor (gdnf), a pivotal regulator of differentiation and survival of dopaminergic neurons, are reportedly decreased in schizophrenia. |
2024-04-27 |
2024-04-29 |
human |
| Laoise Casserly, Daniel R Garton, Ana Montaño-Rodriguez, Jaan-Olle Andresso. Analysis of Acute and Chronic Methamphetamine Treatment in Mice on Gdnf System Expression Reveals a Potential Mechanism of Schizophrenia Susceptibility. Biomolecules. vol 13. issue 9. 2023-09-28. PMID:37759827. |
analysis of acute and chronic methamphetamine treatment in mice on gdnf system expression reveals a potential mechanism of schizophrenia susceptibility. |
2023-09-28 |
2023-10-07 |
mouse |
| Evgeny A Ermakov, Mark M Melamud, Anastasiia S Boiko, Daria A Kamaeva, Svetlana A Ivanova, Georgy A Nevinsky, Valentina N Bunev. Association of Peripheral Inflammatory Biomarkers and Growth Factors Levels with Sex, Therapy and Other Clinical Factors in Schizophrenia and Patient Stratification Based on These Data. Brain sciences. vol 13. issue 5. 2023-05-27. PMID:37239308. |
il-1β, il-2, il-4, il-6, baff, ifn-α, gm-csf, nrg1-β1, and gdnf increased but tnf-α and ngf-β decreased in schizophrenia compared to healthy individuals. |
2023-05-27 |
2023-08-14 |
human |
| Evgeny A Ermakov, Mark M Melamud, Anastasiia S Boiko, Daria A Kamaeva, Svetlana A Ivanova, Georgy A Nevinsky, Valentina N Bunev. Association of Peripheral Inflammatory Biomarkers and Growth Factors Levels with Sex, Therapy and Other Clinical Factors in Schizophrenia and Patient Stratification Based on These Data. Brain sciences. vol 13. issue 5. 2023-05-27. PMID:37239308. |
here, we analyzed changes in serum concentrations of cytokines (il-1β, il-2, il-4, il-6, il-10, il-21, april, baff, pbef/visfatin, ifn-α, and tnf-α) and growth/neurotrophic factors (gm-csf, nrg1-β1, ngf-β, and gdnf) in patients with schizophrenia in an exacerbation phase. |
2023-05-27 |
2023-08-14 |
human |
| Kärt Mätlik, Daniel R Garton, Ana R Montaño-Rodríguez, Soophie Olfat, Feride Eren, Laoise Casserly, Anastasios Damdimopoulos, Anne Panhelainen, L Lauriina Porokuokka, Jaakko J Kopra, Giorgio Turconi, Nadine Schweizer, Erika Bereczki, Fredrik Piehl, Göran Engberg, Simon Cervenka, T Petteri Piepponen, Fu-Ping Zhang, Petra Sipilä, Johan Jakobsson, Carl M Sellgren, Sophie Erhardt, Jaan-Olle Andresso. Elevated endogenous GDNF induces altered dopamine signalling in mice and correlates with clinical severity in schizophrenia. Molecular psychiatry. 2022-05-26. PMID:35618883. |
here, we hypothesized that increased expression of endogenous gdnf could induce dopaminergic abnormalities that resemble those seen in schizophrenia. |
2022-05-26 |
2023-08-13 |
mouse |
| Kärt Mätlik, Daniel R Garton, Ana R Montaño-Rodríguez, Soophie Olfat, Feride Eren, Laoise Casserly, Anastasios Damdimopoulos, Anne Panhelainen, L Lauriina Porokuokka, Jaakko J Kopra, Giorgio Turconi, Nadine Schweizer, Erika Bereczki, Fredrik Piehl, Göran Engberg, Simon Cervenka, T Petteri Piepponen, Fu-Ping Zhang, Petra Sipilä, Johan Jakobsson, Carl M Sellgren, Sophie Erhardt, Jaan-Olle Andresso. Elevated endogenous GDNF induces altered dopamine signalling in mice and correlates with clinical severity in schizophrenia. Molecular psychiatry. 2022-05-26. PMID:35618883. |
elevated endogenous gdnf induces altered dopamine signalling in mice and correlates with clinical severity in schizophrenia. |
2022-05-26 |
2023-08-13 |
mouse |
| Betul Aslan Turkmen, Esra Yazici, Derya Guzel Erdogan, Mehmet Akif Suda, Ahmet Bulent Yazic. BDNF, GDNF, NGF and Klotho levels and neurocognitive functions in acute term of schizophrenia. BMC psychiatry. vol 21. issue 1. 2021-12-03. PMID:34763683. |
bdnf, gdnf, ngf and klotho levels and neurocognitive functions in acute term of schizophrenia. |
2021-12-03 |
2023-08-13 |
Not clear |
| Betul Aslan Turkmen, Esra Yazici, Derya Guzel Erdogan, Mehmet Akif Suda, Ahmet Bulent Yazic. BDNF, GDNF, NGF and Klotho levels and neurocognitive functions in acute term of schizophrenia. BMC psychiatry. vol 21. issue 1. 2021-12-03. PMID:34763683. |
in this study, the hypothesis that the blood serum levels of bdnf, gdnf, ngf and klotho in schizophrenia patients and healthy controls would be related to cognitive functions was investigated. |
2021-12-03 |
2023-08-13 |
Not clear |
| Mona Buhusi, Colten K Brown, Catalin V Buhus. Impaired Latent Inhibition in GDNF-Deficient Mice Exposed to Chronic Stress. Frontiers in behavioral neuroscience. vol 11. 2020-09-30. PMID:29066960. |
our results add li to the list of behaviors affected by chronic stress and support a role for gdnf deficits in stress-induced pathological behaviors relevant to schizophrenia and other psychiatric disorders. |
2020-09-30 |
2023-08-13 |
mouse |
| Xiaowei Tang, Chao Zhou, Ju Gao, Weiwei Duan, Miao Yu, Wenhuan Xiao, Xiaobin Zhang, Hui Dong, Xiang Wang, Xiangrong Zhan. Serum BDNF and GDNF in Chinese male patients with deficit schizophrenia and their relationships with neurocognitive dysfunction. BMC psychiatry. vol 19. issue 1. 2020-04-28. PMID:31420036. |
serum bdnf and gdnf in chinese male patients with deficit schizophrenia and their relationships with neurocognitive dysfunction. |
2020-04-28 |
2023-08-13 |
Not clear |
| Xiaowei Tang, Chao Zhou, Ju Gao, Weiwei Duan, Miao Yu, Wenhuan Xiao, Xiaobin Zhang, Hui Dong, Xiang Wang, Xiangrong Zhan. Serum BDNF and GDNF in Chinese male patients with deficit schizophrenia and their relationships with neurocognitive dysfunction. BMC psychiatry. vol 19. issue 1. 2020-04-28. PMID:31420036. |
to measure the serum levels of brain-derived neurotrophic factor (bdnf) and glial cell line-derived neurotrophic factor (gdnf) in deficit schizophrenia (ds), in order to examine the association between these two neurotrophic factors (nfs) and cognitive performance. |
2020-04-28 |
2023-08-13 |
Not clear |
| Fei Ye, Qiongqiong Zhan, Wenhuan Xiao, Weiwei Sha, Xiaobin Zhan. Altered serum levels of glial cell line-derived neurotrophic factor in male chronic schizophrenia patients with tardive dyskinesia. International journal of methods in psychiatric research. vol 27. issue 4. 2019-04-24. PMID:29901253. |
thus, we examined the serum gdnf levels in schizophrenia patients with td (wtd) and without td (ntd) and compared with healthy controls (hc), respectively. |
2019-04-24 |
2023-08-13 |
Not clear |
| Che-Sheng Chu, Chin-Liang Chu, Chih-Ching Wu, Ti L. Serum nerve growth factor beta, brain- and glial-derived neurotrophic factor levels and psychopathology in unmedicated patients with schizophrenia. Journal of the Chinese Medical Association : JCMA. vol 81. issue 6. 2019-03-22. PMID:29366645. |
this study aimed to explore the relationship between serum nerve growth factor beta (ngf-beta), brain-derived neurotrophic factor (bdnf), and glial-derived neurotrophic factor (gdnf) levels and psychopathology in unmedicated patients with schizophrenia. |
2019-03-22 |
2023-08-13 |
Not clear |
| Maria Skibinska, Pawel Kapelski, Joanna Pawlak, Aleksandra Rajewska-Rager, Monika Dmitrzak-Weglarz, Aleksandra Szczepankiewicz, Piotr Czerski, Joanna Twarowska-Hause. Glial Cell Line-Derived Neurotrophic Factor (GDNF) serum level in women with schizophrenia and depression, correlation with clinical and metabolic parameters. Psychiatry research. vol 256. 2018-04-30. PMID:28689143. |
this study examined serum levels of gdnf in schizophrenia and depression and its correlation with metabolic parameters during 8 weeks of treatment. |
2018-04-30 |
2023-08-13 |
Not clear |
| Maria Skibinska, Pawel Kapelski, Joanna Pawlak, Aleksandra Rajewska-Rager, Monika Dmitrzak-Weglarz, Aleksandra Szczepankiewicz, Piotr Czerski, Joanna Twarowska-Hause. Glial Cell Line-Derived Neurotrophic Factor (GDNF) serum level in women with schizophrenia and depression, correlation with clinical and metabolic parameters. Psychiatry research. vol 256. 2018-04-30. PMID:28689143. |
glial cell line-derived neurotrophic factor (gdnf) serum level in women with schizophrenia and depression, correlation with clinical and metabolic parameters. |
2018-04-30 |
2023-08-13 |
Not clear |
| Wenhuan Xiao, Fei Ye, Chunlai Liu, Xiaowei Tang, Jin Li, Hui Dong, Weiwei Sha, Xiaobin Zhan. Cognitive impairment in first-episode drug-naïve patients with schizophrenia: Relationships with serum concentrations of brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor. Progress in neuro-psychopharmacology & biological psychiatry. vol 76. 2018-04-02. PMID:28342945. |
our work aimed at exploring the associations between serum bdnf and gdnf levels and cognitive functions in first-episode drug-naïve (fedn) patients with schizophrenia. |
2018-04-02 |
2023-08-13 |
Not clear |
| Wenhuan Xiao, Fei Ye, Li Ma, Xiaowei Tang, Jin Li, Hui Dong, Weiwei Sha, Xiaobin Zhan. Atypical antipsychotic treatment increases glial cell line-derived neurotrophic factor serum levels in drug-free schizophrenic patients along with improvement of psychotic symptoms and therapeutic effects. Psychiatry research. vol 246. 2017-12-08. PMID:27836239. |
the present study suggests that gdnf may be involved in the etiology of schizophrenia and pharmacological treatment. |
2017-12-08 |
2023-08-13 |
human |
| Wenhuan Xiao, Fei Ye, Li Ma, Xiaowei Tang, Jin Li, Hui Dong, Weiwei Sha, Xiaobin Zhan. Atypical antipsychotic treatment increases glial cell line-derived neurotrophic factor serum levels in drug-free schizophrenic patients along with improvement of psychotic symptoms and therapeutic effects. Psychiatry research. vol 246. 2017-12-08. PMID:27836239. |
the aims of this study were to investigate the serum concentration of gdnf, to monitor the therapeutic effect of atypical antipsychotics related to gdnf levels in drug-free schizophrenia patients, and to examine these levels in relation to psychotic symptoms. |
2017-12-08 |
2023-08-13 |
human |