| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Gergely Keszler, Bálint Vékony, Zsuzsanna Elek, Zsófia Nemoda, Nóra Angyal, Zsófia Bánlaki, Réka Kovács-Nagy, Zsolt Rónai, János M Réthely. MicroRNA-Mediated Suppression of Glial Cell Line-Derived Neurotrophic Factor Expression Is Modulated by a Schizophrenia-Associated Non-Coding Polymorphism. International journal of molecular sciences. vol 25. issue 8. 2024-04-27. PMID:38674063. |
plasma levels of glial cell line-derived neurotrophic factor (gdnf), a pivotal regulator of differentiation and survival of dopaminergic neurons, are reportedly decreased in schizophrenia. |
2024-04-27 |
2024-04-29 |
human |
| Gabriela Novak, Mary V Seema. Dopamine, Psychosis, and Symptom Fluctuation: A Narrative Review. Healthcare (Basel, Switzerland). vol 10. issue 9. 2022-09-23. PMID:36141325. |
the review also includes new discoveries in schizophrenia research, pointing to the involvement of both striatal neurons and glia, signaling pathway convergence, and the role of stress. |
2022-09-23 |
2023-08-14 |
Not clear |
| Yutaka Nakagawa, Shizuo Yamad. The Relationships Among Metal Homeostasis, Mitochondria, and Locus Coeruleus in Psychiatric and Neurodegenerative Disorders: Potential Pathogenetic Mechanism and Therapeutic Implications. Cellular and molecular neurobiology. 2022-05-31. PMID:35635600. |
data suggest that the onset of major depressive disorder and schizophrenia is associated with metal dyshomeostasis that causes glial cell mitochondrial dysfunction and hyperactivation in the locus coeruleus. |
2022-05-31 |
2023-08-13 |
Not clear |
| Shu-Han Liu, Yang Du, Lei Chen, Yong Chen. Glial Cell Abnormalities in Major Psychiatric Diseases: A Systematic Review of Postmortem Brain Studies. Molecular neurobiology. 2022-01-11. PMID:35013935. |
there have been a large number of reports about glial cell dysfunction being related to major psychiatric diseases such as schizophrenia (scz), bipolar disorder (bd), and major depressive disorder (mdd). |
2022-01-11 |
2023-08-13 |
Not clear |
| Ruqayya Afridi, Sihwan Seol, Hyo Jung Kang, Kyoungho Su. Brain-immune interactions in neuropsychiatric disorders: Lessons from transcriptome studies for molecular targeting. Biochemical pharmacology. vol 188. 2021-09-14. PMID:33773976. |
recent transcriptome studies have identified dysregulated genes involved in peripheral immune cell activation, blood-brain barrier integrity, glial cell activation, and synaptic plasticity in major depressive disorder, bipolar disorder, autism spectrum disorder, and schizophrenia. |
2021-09-14 |
2023-08-13 |
Not clear |
| Lin Zhang, Ronald W H Verwer, Paul J Lucassen, Inge Huitinga, Dick F Swaa. Prefrontal cortex alterations in glia gene expression in schizophrenia with and without suicide. Journal of psychiatric research. vol 121. 2021-03-24. PMID:31739114. |
prefrontal cortex alterations in glia gene expression in schizophrenia with and without suicide. |
2021-03-24 |
2023-08-13 |
Not clear |
| Xiaowei Zhu, Bo Zhou, Reenal Pattni, Kelly Gleason, Chunfeng Tan, Agnieszka Kalinowski, Steven Sloan, Anna-Sophie Fiston-Lavier, Jessica Mariani, Dmitri Petrov, Ben A Barres, Laramie Duncan, Alexej Abyzov, Hannes Vogel, John V Moran, Flora M Vaccarino, Carol A Tamminga, Douglas F Levinson, Alexander E Urba. Machine learning reveals bilateral distribution of somatic L1 insertions in human neurons and glia. Nature neuroscience. vol 24. issue 2. 2021-03-19. PMID:33432196. |
we characterized two brain-specific l1 insertions in neurons and glia from a donor with schizophrenia. |
2021-03-19 |
2023-08-13 |
human |
| Daniela Rodrigues-Amorim, Tania Rivera-Baltanás, María Del Carmen Vallejo-Curto, Cynthia Rodriguez-Jamardo, Elena de Las Heras, Carolina Barreiro-Villar, María Blanco-Formoso, Patricia Fernández-Palleiro, María Álvarez-Ariza, Marta López, Alejandro García-Caballero, José Manuel Olivares, Carlos Spuc. Proteomics in Schizophrenia: A Gateway to Discover Potential Biomarkers of Psychoneuroimmune Pathways. Frontiers in psychiatry. vol 10. 2020-10-01. PMID:31849731. |
the analysis revealed a significant reduction in the levels of glia maturation factor beta (gmf-β), the brain-derived neurotrophic factor (bdnf), and the 115-kda isoform of the rab3 gtpase-activating protein catalytic subunit (rab3gap1) in patients with schizophrenia as compared to healthy volunteers. |
2020-10-01 |
2023-08-13 |
human |
| Sergi Papiol, Daniel Keeser, Alkomiet Hasan, Thomas Schneider-Axmann, Florian Raabe, Franziska Degenhardt, Moritz J Rossner, Heike Bickeböller, Ludovico Cantuti-Castelvetri, Mikael Simons, Thomas Wobrock, Andrea Schmitt, Berend Malchow, Peter Falka. Polygenic burden associated to oligodendrocyte precursor cells and radial glia influences the hippocampal volume changes induced by aerobic exercise in schizophrenia patients. Translational psychiatry. vol 9. issue 1. 2020-08-05. PMID:31712617. |
polygenic burden associated to oligodendrocyte precursor cells and radial glia influences the hippocampal volume changes induced by aerobic exercise in schizophrenia patients. |
2020-08-05 |
2023-08-13 |
Not clear |
| Xiaowei Tang, Chao Zhou, Ju Gao, Weiwei Duan, Miao Yu, Wenhuan Xiao, Xiaobin Zhang, Hui Dong, Xiang Wang, Xiangrong Zhan. Serum BDNF and GDNF in Chinese male patients with deficit schizophrenia and their relationships with neurocognitive dysfunction. BMC psychiatry. vol 19. issue 1. 2020-04-28. PMID:31420036. |
to measure the serum levels of brain-derived neurotrophic factor (bdnf) and glial cell line-derived neurotrophic factor (gdnf) in deficit schizophrenia (ds), in order to examine the association between these two neurotrophic factors (nfs) and cognitive performance. |
2020-04-28 |
2023-08-13 |
Not clear |
| Chao Chen, Qingtuan Meng, Yan Xia, Chaodong Ding, Le Wang, Rujia Dai, Lijun Cheng, Preethi Gunaratne, Richard A Gibbs, Shishi Min, Cristian Coarfa, Jeffrey G Reid, Chunling Zhang, Chuan Jiao, Yi Jiang, Gina Giase, Amber Thomas, Dominic Fitzgerald, Tonya Brunetti, Annie Shieh, Cuihua Xia, Yongjun Wang, Yunpeng Wang, Judith A Badner, Elliot S Gershon, Kevin P White, Chunyu Li. The transcription factor POU3F2 regulates a gene coexpression network in brain tissue from patients with psychiatric disorders. Science translational medicine. vol 10. issue 472. 2019-10-11. PMID:30545964. |
this module contained genes that were principally involved in glial and neural cell genesis and glial cell differentiation, and included schizophrenia risk genes carrying rare variants. |
2019-10-11 |
2023-08-13 |
human |
| Giuliana S Zuccoli, Paul C Guest, Daniel Martins-de-Souz. Effects on Glial Cell Glycolysis in Schizophrenia: An Advanced Aging Phenotype? Advances in experimental medicine and biology. vol 1178. 2019-09-18. PMID:31493220. |
effects on glial cell glycolysis in schizophrenia: an advanced aging phenotype? |
2019-09-18 |
2023-08-13 |
Not clear |
| Robin J M Franklin, Edward T Bullmor. Do Not Adjust Your Mind: The Fault Is in Your Glia. Cell stem cell. vol 21. issue 2. 2019-06-13. PMID:28777939. |
(2017) transplant human glial progenitors from schizophrenia patients into mouse brains, which develop abnormalities and behaviors characteristic of schizophrenia, thereby suggesting a primary role for glia in the complex disease pathogenesis. |
2019-06-13 |
2023-08-13 |
mouse |
| Anna Vilalta, Guy C Brow. Neurophagy, the phagocytosis of live neurons and synapses by glia, contributes to brain development and disease. The FEBS journal. vol 285. issue 19. 2019-06-07. PMID:29125686. |
phagocytosis of live synapses, dendrites and axons by glia contributes to experience-dependent sculpting of neuronal networks during development, but excessive phagocytosis of synapses may contribute to pathology in alzheimer's disease, schizophrenia and ageing. |
2019-06-07 |
2023-08-13 |
human |
| Fei Ye, Qiongqiong Zhan, Wenhuan Xiao, Weiwei Sha, Xiaobin Zhan. Altered serum levels of glial cell line-derived neurotrophic factor in male chronic schizophrenia patients with tardive dyskinesia. International journal of methods in psychiatric research. vol 27. issue 4. 2019-04-24. PMID:29901253. |
altered serum levels of glial cell line-derived neurotrophic factor in male chronic schizophrenia patients with tardive dyskinesia. |
2019-04-24 |
2023-08-13 |
Not clear |
| Allyson P Mallya, Ariel Y Deutc. (Micro)Glia as Effectors of Cortical Volume Loss in Schizophrenia. Schizophrenia bulletin. vol 44. issue 5. 2019-02-08. PMID:30124942. |
(micro)glia as effectors of cortical volume loss in schizophrenia. |
2019-02-08 |
2023-08-13 |
Not clear |
| Katherine E Tansey, Matthew J Hil. Enrichment of schizophrenia heritability in both neuronal and glia cell regulatory elements. Translational psychiatry. vol 8. issue 1. 2018-12-18. PMID:29317610. |
enrichment of schizophrenia heritability in both neuronal and glia cell regulatory elements. |
2018-12-18 |
2023-08-13 |
human |
| Russell W Brown, Marjorie A Schlitt, Alex S Owens, Caitlynn C DePreter, Elizabeth D Cummins, Seth L Kirby, W Drew Gill, Katherine C Burges. Effects of Environmental Enrichment on Nicotine Sensitization in Rats Neonatally Treated with Quinpirole: Analyses of Glial Cell Line-Derived Neurotrophic Factor and Implications towards Schizophrenia. Developmental neuroscience. vol 40. issue 1. 2018-10-16. PMID:29444518. |
effects of environmental enrichment on nicotine sensitization in rats neonatally treated with quinpirole: analyses of glial cell line-derived neurotrophic factor and implications towards schizophrenia. |
2018-10-16 |
2023-08-13 |
rat |
| Maria Skibinska, Pawel Kapelski, Joanna Pawlak, Aleksandra Rajewska-Rager, Monika Dmitrzak-Weglarz, Aleksandra Szczepankiewicz, Piotr Czerski, Joanna Twarowska-Hause. Glial Cell Line-Derived Neurotrophic Factor (GDNF) serum level in women with schizophrenia and depression, correlation with clinical and metabolic parameters. Psychiatry research. vol 256. 2018-04-30. PMID:28689143. |
glial cell line-derived neurotrophic factor (gdnf) serum level in women with schizophrenia and depression, correlation with clinical and metabolic parameters. |
2018-04-30 |
2023-08-13 |
Not clear |
| Buranee Kanchanatawan, Sunee Sirivichayakul, Supaksorn Thika, Kiat Ruxrungtham, André F Carvalho, Michel Geffard, George Anderson, Cristiano Noto, Rada Ivanova, Michael Mae. Physio-somatic symptoms in schizophrenia: association with depression, anxiety, neurocognitive deficits and the tryptophan catabolite pathway. Metabolic brain disease. vol 32. issue 4. 2018-04-23. PMID:28258445. |
as such, the patterning of iga/igm responses to trycats may indicate differential trycats regulation of neuronal and glia activity that act to regulate ps signalling in schizophrenia. |
2018-04-23 |
2023-08-13 |
Not clear |