| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Andrea D Rivera, John R Normanton, Arthur M Butt, Kasum Azi. The Genomic Intersection of Oligodendrocyte Dynamics in Schizophrenia and Aging Unravels Novel Pathological Mechanisms and Therapeutic Potentials. International journal of molecular sciences. vol 25. issue 8. 2024-04-27. PMID:38674040. |
the genomic intersection of oligodendrocyte dynamics in schizophrenia and aging unravels novel pathological mechanisms and therapeutic potentials. |
2024-04-27 |
2024-04-29 |
Not clear |
| Andrea D Rivera, John R Normanton, Arthur M Butt, Kasum Azi. The Genomic Intersection of Oligodendrocyte Dynamics in Schizophrenia and Aging Unravels Novel Pathological Mechanisms and Therapeutic Potentials. International journal of molecular sciences. vol 25. issue 8. 2024-04-27. PMID:38674040. |
notably, a decline in a specific subpopulation of opc has been identified as a principal factor in oligodendrocyte disruption and white matter loss in the aging brain, suggesting this may also be a factor in schizophrenia. |
2024-04-27 |
2024-04-29 |
Not clear |
| Gina Shim, Alejandra I Romero-Morales, Srinidhi R Sripathy, Brady J Mahe. Utilizing hiPSC-derived oligodendrocytes to study myelin pathophysiology in neuropsychiatric and neurodegenerative disorders. Frontiers in cellular neuroscience. vol 17. 2024-01-26. PMID:38273973. |
oligodendrocyte dysfunction and/or dysmyelination can contribute to a range of neurodegenerative diseases and neuropsychiatric disorders such as multiple sclerosis (ms), leukodystrophy (ld), schizophrenia (scz), and autism spectrum disorder (asd). |
2024-01-26 |
2024-01-28 |
human |
| N S Kolomeets, N A Uranov. [Reduced numerical density of oligodendrocytes and oligodendrocyte clusters in the head of the caudate nucleus in schizophrenia]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. vol 123. issue 1. 2023-01-31. PMID:36719125. |
[reduced numerical density of oligodendrocytes and oligodendrocyte clusters in the head of the caudate nucleus in schizophrenia]. |
2023-01-31 |
2023-08-14 |
Not clear |
| N S Kolomeets, N A Uranov. [Reduced numerical density of oligodendrocytes and oligodendrocyte clusters in the head of the caudate nucleus in schizophrenia]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. vol 123. issue 1. 2023-01-31. PMID:36719125. |
morphometric estimation of the numerical density of oligodendrocytes (ncol) and numerical density of oligodendrocyte clusters (nvolc) in the rostral part of the caudate head nucleus associated with the cortical regions of the default network in the norm and in schizophrenia. |
2023-01-31 |
2023-08-14 |
Not clear |
| Andrea Schmitt, Laura Tatsch, Alisa Vollhardt, Thomas Schneider-Axmann, Florian J Raabe, Lukas Roell, Helmut Heinsen, Patrick R Hof, Peter Falkai, Christoph Schmit. Decreased Oligodendrocyte Number in Hippocampal Subfield CA4 in Schizophrenia: A Replication Study. Cells. vol 11. issue 20. 2022-10-27. PMID:36291109. |
decreased oligodendrocyte number in hippocampal subfield ca4 in schizophrenia: a replication study. |
2022-10-27 |
2023-08-14 |
Not clear |
| Andrea Schmitt, Laura Tatsch, Alisa Vollhardt, Thomas Schneider-Axmann, Florian J Raabe, Lukas Roell, Helmut Heinsen, Patrick R Hof, Peter Falkai, Christoph Schmit. Decreased Oligodendrocyte Number in Hippocampal Subfield CA4 in Schizophrenia: A Replication Study. Cells. vol 11. issue 20. 2022-10-27. PMID:36291109. |
by using unbiased design-based stereology, we reported a reduction in oligodendrocyte number in ca4 in schizophrenia and of granular neurons in the dentate gyrus (dg). |
2022-10-27 |
2023-08-14 |
Not clear |
| Andrea Schmitt, Laura Tatsch, Alisa Vollhardt, Thomas Schneider-Axmann, Florian J Raabe, Lukas Roell, Helmut Heinsen, Patrick R Hof, Peter Falkai, Christoph Schmit. Decreased Oligodendrocyte Number in Hippocampal Subfield CA4 in Schizophrenia: A Replication Study. Cells. vol 11. issue 20. 2022-10-27. PMID:36291109. |
our results replicate the previously described decrease in oligodendrocytes bilaterally in ca4 in schizophrenia and point to a deficit in oligodendrocyte maturation or a loss of mature oligodendrocytes. |
2022-10-27 |
2023-08-14 |
Not clear |
| Bradley Joseph Smith, Caroline Brandão-Teles, Giuliana S Zuccoli, Guilherme Reis-de-Oliveira, Mariana Fioramonte, Verônica M Saia-Cereda, Daniel Martins-de-Souz. Protein Succinylation and Malonylation as Potential Biomarkers in Schizophrenia. Journal of personalized medicine. vol 12. issue 9. 2022-09-23. PMID:36143193. |
in this work, data from shotgun mass spectrometry-based quantitative proteomics were compiled and analyzed to probe the succinylome and malonylome of postmortem brain tissue from patients with schizophrenia against controls and the human oligodendrocyte precursor cell line mo3.13 with the dizocilpine chemical model for schizophrenia, three antipsychotics, and co-treatments. |
2022-09-23 |
2023-08-14 |
human |
| Jeffrey Fesse. Abnormal oligodendrocyte function in schizophrenia explains the long latent interval in some patients. Translational psychiatry. vol 12. issue 1. 2022-03-26. PMID:35338111. |
abnormal oligodendrocyte function in schizophrenia explains the long latent interval in some patients. |
2022-03-26 |
2023-08-13 |
Not clear |
| Jeffrey Fesse. Abnormal oligodendrocyte function in schizophrenia explains the long latent interval in some patients. Translational psychiatry. vol 12. issue 1. 2022-03-26. PMID:35338111. |
abnormalities in oligodendrocyte function may explain this latency, because mature oligodendrocytes produce myelination, and if myelination were abnormal from the outset, it would cause the synaptic dysfunction and abnormal neural tracts that are underpinning features of schizophrenia. |
2022-03-26 |
2023-08-13 |
Not clear |
| Meng Liu, Miaomiao Zheng, Weiwei Zhang, Fan Yang, Lan Hong, Xin Yu, Haiyun X. Cuprizone-induced dopaminergic hyperactivity and locomotor deficit in zebrafish larvae. Brain research. 2022-01-27. PMID:35085574. |
recent studies have shown oligodendrocyte (ol) loss and demyelination along with dopamine (da) increase and behavioral abnormalities in cpz-exposed mice, demonstrating its application in schizophrenia research. |
2022-01-27 |
2023-08-13 |
mouse |
| Natalya S Kolomeets, Natalya A Uranov. Reduced number of satellite oligodendrocytes of pyramidal neurons in layer 5 of the prefrontal cortex in schizophrenia. European archives of psychiatry and clinical neuroscience. 2021-11-25. PMID:34822006. |
previously we reported a significant deficit of oligodendrocytes and oligodendrocyte clusters in layers 3 and 5 of the prefrontal cortex, brodmann area 10 (ba10) in schizophrenia. |
2021-11-25 |
2023-08-13 |
Not clear |
| Natalya S Kolomeets, Natalya A Uranov. Reduced number of satellite oligodendrocytes of pyramidal neurons in layer 5 of the prefrontal cortex in schizophrenia. European archives of psychiatry and clinical neuroscience. 2021-11-25. PMID:34822006. |
in this current study, we investigate the number of oligodendrocyte satellites (sat-ol) per pyramidal neuron in layer 5 of ba10 in schizophrenia (n = 17) as compared to healthy controls (n = 20) in the same section collection as previously used to study the numerical density (nv) of oligodendrocytes and oligodendrocyte clusters. |
2021-11-25 |
2023-08-13 |
Not clear |
| Rita De Gasperi, Miguel A Gama Sosa, Zuzanna Naumowicz, Patrick R Hof, Lucia Notterpek, Kenneth L Davis, Joseph D Buxbaum, Gregory A Elde. PERIPHERAL MYELIN PROTEIN-22 IS EXPRESSED IN CNS MYELIN. Translational neuroscience. vol 1. issue 4. 2021-10-20. PMID:21572910. |
myelin abnormalities exist in schizophrenia leading to the hypothesis that oligodendrocyte dysfunction plays a role in the pathophysiology of the disease. |
2021-10-20 |
2023-08-12 |
mouse |
| Natalya S Kolomeets, Natalya A Uranov. Numerical density of oligodendrocytes and oligodendrocyte clusters in the anterior putamen in major psychiatric disorders. European archives of psychiatry and clinical neuroscience. vol 270. issue 7. 2021-06-28. PMID:32060609. |
previously we reported a reduction in the numerical density of oligodendrocytes and oligodendrocyte clusters in the prefrontal and parietal cortex in schizophrenia. |
2021-06-28 |
2023-08-13 |
human |
| Natalya S Kolomeets, Natalya A Uranov. Numerical density of oligodendrocytes and oligodendrocyte clusters in the anterior putamen in major psychiatric disorders. European archives of psychiatry and clinical neuroscience. vol 270. issue 7. 2021-06-28. PMID:32060609. |
a significant reduction in both the nv of oligodendrocytes (- 34%; p < 0.01) and the nv of oligodendrocyte clusters (- 41%; p < 0.05) was found in the schizophrenia group as compared to the control group. |
2021-06-28 |
2023-08-13 |
human |
| Natalya S Kolomeets, Natalya A Uranov. Numerical density of oligodendrocytes and oligodendrocyte clusters in the anterior putamen in major psychiatric disorders. European archives of psychiatry and clinical neuroscience. vol 270. issue 7. 2021-06-28. PMID:32060609. |
the data suggest that lowered density of oligodendrocytes and oligodendrocyte clusters may contribute to the altered functional connectivity in the putamen in subjects with schizophrenia. |
2021-06-28 |
2023-08-13 |
human |
| Janice Bloc. High risk genotypes for schizophrenia may have been adaptive in the context of smallpox. Medical hypotheses. vol 137. 2021-05-14. PMID:31935637. |
indeed, the set of cellular and tissue processes influenced by schizophrenia - including manipulations of oligodendrocyte development, complement mediated immunity, vrk2, sulfation of heparin, il-18, availability of glutamate, and interactions with sex hormones - overlaps with the set of cellular and tissue processes affected during vaccinia encephalitis. |
2021-05-14 |
2023-08-13 |
Not clear |
| Xianjun Chen, Nan-Xin Huang, Yong-Jie Cheng, Qi-Yan Cai, Yan-Ping Tian, Xing-Shu Chen, Lan Xia. DNA Hypermethylation Induced by L-Methionine Leads to Oligodendroglial and Myelin Deficits and Schizophrenia-Like Behaviors in Adolescent Mice. Frontiers in neuroscience. vol 15. 2021-05-08. PMID:33958986. |
this study provides new insights into the possibility that precise modulation of dna methylation status in oligodendroglia could be beneficial for the white matter pathology in schizophrenia. |
2021-05-08 |
2023-08-13 |
mouse |