| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Miao Ding, Yu Yang, Ziyang Zhang, Hongxiang Liu, Yingdi Dai, Zixuan Wang, Sijia Ma, Yang Liu, Qi Wan. Structural characterization of the polysaccharide from the black crystal region of Inonotus obliquus and its effect on AsPC-1 and SW1990 pancreatic cancer cell apoptosis. International journal of biological macromolecules. 2024-04-27. PMID:38677687. |
furthermore, western blot analysis confirmed that iop1-1 could induce apoptosis in aspc-1 and sw1990 pancreatic cancer cells through three pathways: the mitochondrial pathway, the death receptor pathway, and endoplasmic reticulum stress. |
2024-04-27 |
2024-04-30 |
Not clear |
| Menghuan Yang, Jun Jiang, Ruimin Ren, Ning Gao, Jun He, Yuebo Zhan. Role of ADAR1 on Proliferation and Differentiation in Porcine Preadipocytes. Animals : an open access journal from MDPI. vol 14. issue 8. 2024-04-27. PMID:38672349. |
in this study, we investigated the role of adar1 in differentiation, proliferation and apoptosis of porcine preadipocytes using cck-8, edu staining, cell cycle detection, rt-qpcr, western blot, a triglyceride assay and oil red o staining. |
2024-04-27 |
2024-04-29 |
mouse |
| Rak Ho Son, Myeong Il Kim, Hye Mi Kim, Shuo Guo, Do Hyun Lee, Gyu Min Lim, Seong-Min Kim, Jae-Yong Kim, Chul Young Ki. Potential of Lycii Radicis Cortex as an Ameliorative Agent for Skeletal Muscle Atrophy. Pharmaceuticals (Basel, Switzerland). vol 17. issue 4. 2024-04-27. PMID:38675422. |
we evaluated the effect of lrce on improving muscle atrophy using a variety of methods, including immunofluorescence staining, quantitative polymerase chain reaction (qpcr), western blot, measurements of oxidative stress, apoptosis, atp levels, and muscle tissue analysis. |
2024-04-27 |
2024-04-29 |
mouse |
| P G Roopashree, Shilpa S Shetty, Vijith Vittal Shetty, P C Suhasini, Kumari N Sucheth. Inhibitory effects of medium-chain fatty acids on the proliferation of human breast cancer cells via suppression of Akt/mTOR pathway and modulating the Bcl-2 family protein. Journal of cellular biochemistry. 2024-04-26. PMID:38666486. |
to investigate the apoptosis-inducing effect of mcfas in breast cancer cells, cell viability assay, colony formation assay, cell migration assay, cell invasion assay, nuclear morphology, cell cycle assay, intracellular reactive oxygen species (ros), matrix metalloproteinase (mmp), apoptosis, rt-qpcr analysis, and western blot analysis were performed. |
2024-04-26 |
2024-04-28 |
human |
| Wei-Zhe Liang, Yuan-Yi Chia, Huai-Jhih Sun, Gwo-Ching Su. Exploration of beauvericin's toxic effects and mechanisms in human astrocytes and N-acetylcysteine's protective role. Toxicon : official journal of the International Society on Toxinology. 2024-04-26. PMID:38670497. |
western blot analysis of cells treated with bea revealed altered protein levels of bax, cleaved caspase-9, and caspase-3, along with an increased bax/bcl-2 ratio, indicating the induction of apoptosis. |
2024-04-26 |
2024-04-29 |
human |
| Jiuming Dai, Jin Liu, Yucheng Shen, Bing Zhang, Chaonian Li, Zhidong Li. Regulation of endoplasmic reticulum stress on autophagy and apoptosis of nucleus pulposus cells in intervertebral disc degeneration and its related mechanisms. PeerJ. vol 12. 2024-04-26. PMID:38666076. |
cell apoptosis was detected by flow cytometry and the expression of lc3ii/i was detected by western blot. |
2024-04-26 |
2024-04-28 |
Not clear |
| Jiuming Dai, Jin Liu, Yucheng Shen, Bing Zhang, Chaonian Li, Zhidong Li. Regulation of endoplasmic reticulum stress on autophagy and apoptosis of nucleus pulposus cells in intervertebral disc degeneration and its related mechanisms. PeerJ. vol 12. 2024-04-26. PMID:38666076. |
then, above functional experiments were conducted again and western blot was employed for the evaluation of autophagy-, apoptosis and ers-related proteins. |
2024-04-26 |
2024-04-28 |
Not clear |
| Sheng-Yun Wu, Ke-Ru Cheng, Yan-Yun Zhou, Yin-Fang Wan. [Microtubule-associated tumor suppressor 1 inhibits hemin-induced apoptosis of vascular endothelial cells via hemeoxygenase 1]. Sheng li xue bao : [Acta physiologica Sinica]. vol 76. issue 2. 2024-04-25. PMID:38658371. |
the effect of mtus1 or hmox1 knockdown on hemin-induced apoptosis in huvec, and the overexpression of nrf2 on hemin-induced apoptosis in mtus1 knockdown 293t cells were assayed with cck8 and western blot. |
2024-04-25 |
2024-04-28 |
human |
| Yunhao Jia, Han Yang, Jinsong Yu, Zhong Li, Guangwei Jia, Bo Din. Crocin enhances the sensitivity to paclitaxel in human breast cancer cells by reducing BIRC5 expression. Chemical biology & drug design. vol 103. issue 2. 2024-04-25. PMID:38661582. |
baculoviral inhibitor of apoptosis repeat containing 5 (birc5) expression was detected by qrt-pcr and western blot analysis. |
2024-04-25 |
2024-04-28 |
human |
| Zhiguang Liu, Chuang Sun, Yujia Shi, Zhipeng Wang, Lianzheng Zhou, Qian Zhang, Zhengdao Ma. MiR-4454 in Combined Allergic Rhinitis and Asthma Syndrome (CARAS): Clinical significance and mechanistic insights into airway inflammation. Cellular and molecular biology (Noisy-le-Grand, France). vol 70. issue 3. 2024-04-23. PMID:38650129. |
house dust mite (hdm) sensitization and challenge-induced bronchial epithelial cells to simulate the asthma state model in vitro, mir-4454 mimics and inhibitor transfection to detect the expression level of pro-inflammatory cytokines, cell survival rate and migration ability, flow cytometry and western blot (wb) detection of cell cycle, apoptosis and inflammation-related protein levels. |
2024-04-23 |
2024-04-26 |
human |
| Kurnegala Manikanta, Manoj Paul, Vaddaragudisalu D Sandesha, Shanmuga S Mahalingam, Thimmasandra Narayan Ramesh, Krishnegowda Harishkumar, Shashank S Koundinya, Shivanna Naveen, Kempaiah Kemparaju, Kesturu S Giris. Oxidative Stress-Induced Platelet Apoptosis/Activation: Alleviation by Purified Curcumin via ASK1-JNK/p-38 Pathway. Biochemistry. Biokhimiia. vol 89. issue 3. 2024-04-22. PMID:38648762. |
western blot analysis confirms protective effect of the purified curcumin against oxidative stress-induced platelet apoptosis and activation via downregulation of mapks protein activation, including ask1, jnk, and p-38. |
2024-04-22 |
2024-04-26 |
Not clear |
| Hongjuan Duan, Shaojin Li, Chuangwei Li, Lan Tian, Yun Ma, Xiaoyan Ca. Alfalfa xeno-miR159a regulates bovine mammary epithelial cell proliferation and milk protein synthesis by targeting PTPRF. Scientific reports. vol 14. issue 1. 2024-04-20. PMID:38643232. |
cell proliferation and apoptosis were detected using the cell counting kit 8 (cck-8) assay, 5-ethynyl-2'-deoxyuridine (edu) staining, western blot, and flow cytometry. |
2024-04-20 |
2024-04-23 |
cattle |
| Fatma Uysal, Gozde Sukur, Nazlican Bozdemir, Ozgur Cina. Antioxidant supplementation may effect DNA methylation patterns, apoptosis, and ROS levels in developing mouse embryos. Histochemistry and cell biology. 2024-04-16. PMID:38627305. |
protein expression levels of dnmt1, 3a, 3b, and 3l enzymes were analyzed by immunofluorescence and western blot, while global dna methylation, apoptosis, and ros levels were evaluated by immunofluorescence. |
2024-04-16 |
2024-04-19 |
mouse |
| Yining Lei, Manqin Li, Xinran Liu, Lu Zhang, Ruyi Zhang, Fei Ca. Nerolidol rescues hippocampal injury of diabetic rats through inhibiting NLRP3 inflammasome and regulation of MAPK/AKT pathway. BioFactors (Oxford, England). 2024-04-16. PMID:38624190. |
western blot was used to detect apoptosis (bcl-2, bax, and cleaved-caspase-3); synapses (postsynaptic densifying protein 95, syn1, and synaptophysin); mitochondria (drp1, opa1, mfn1, and mfn2); er (grp78, atf6, chop, and caspase-12); nlrp3 inflammasome (nlrp3, asc, and caspase-1); inflammatory cytokines (il-18, il-1β, and tnf-α); akt (p-akt); and mitogen-activated protein kinase (mapk) pathway (p-erk, p-p38, and p-jnk) related protein expression. |
2024-04-16 |
2024-04-18 |
rat |
| Ye-Won Kim, Seul-Gi Yang, Byoung-Boo Seo, Deog-Bon Koo, Hyo-Jin Par. Deoxynivalenol leads to endoplasmic reticulum stress-mediated apoptosis via the IRE1/JNK/CHOP pathways in porcine embryos. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2024-04-12. PMID:38608924. |
western blot analysis showed that ire1/jnk/chop signaling was activated in don-exposed porcine embryos, indicating that er stress-associated apoptosis was instigated. |
2024-04-12 |
2024-04-15 |
Not clear |
| Showkat Ali Ganie, Rayees Ahmad Naik, Ovas Ahmad Dar, Luqman Jameel Rather, Mohammed A Assiri, Qing L. Design and fabrication of functionalized curdlan-curcumin delivery system to facilitate the therapeutic effects of curcumin on breast cancer. International journal of biological macromolecules. 2024-04-12. PMID:38608982. |
the results obtained from western blot analysis demonstrated that the co-administration of cur and cum effectively induced apoptosis in mcf-7 cells. |
2024-04-12 |
2024-04-15 |
Not clear |
| Xiaomeng Xu, Cheng Yin, Bing Dong, Yuewen Li, Shi Liu, Jun Che. LncRNA XIST Protects Against Polycystic Ovary Syndrome via the Regulation of miR-212-3p/RASA1 Axis. Biochemical genetics. 2024-04-12. PMID:38609670. |
cell viability, apoptosis, protein expression of bcl-2 and bax were assessed by mtt, flow cytometry analysis, rt-qpcr and western blot, respectively. |
2024-04-12 |
2024-04-15 |
Not clear |
| Mingbao Gu, Chenchao Li, Qingyu Deng, Ximiao Chen, Rui Le. Celastrol enhances the viability of random-pattern skin flaps by regulating autophagy through the AMPK-mTOR-TFEB axis. Phytotherapy research : PTR. 2024-04-11. PMID:38600729. |
the effects of cel on flap angiogenesis, apoptosis, oxidative stress, and autophagy were evaluated by western blot, immunohistochemistry, and immunofluorescence assays. |
2024-04-11 |
2024-04-13 |
Not clear |
| Xunxia Zhu, Xiaoyu Chen, Xuelin Zhang, Liting Zhao, Xiaoyong She. MicroRNA‑373‑3p inhibits the proliferation and invasion of non‑small‑cell lung cancer cells by targeting the GAB2/PI3K/AKT pathway. Oncology letters. vol 27. issue 5. 2024-04-08. PMID:38586211. |
to further examine how mir-373 mediates the emergence of nsclc, western blot, cell counting kit-8, cell invasion and wound-healing assays, as well as apoptosis detection and a luciferase assay were used. |
2024-04-08 |
2024-04-10 |
Not clear |
| Zhitong Lin, Chen Liu, Ziqin Yan, Jing Cheng, Xiancheng Wang, Feilong Zhou, Xilin Lyu, Shiyan Zhang, Daizhou Zhang, Xiangjing Meng, Yujun Zha. Synthesis and biological evaluation of 4-imidazolidinone-containing compounds as potent inhibitors of the MDM2/p53 interaction. European journal of medicinal chemistry. vol 270. 2024-04-06. PMID:38581730. |
mechanistic studies show that 2 and 22 dose-dependently activated p53 and its target genes and induced apoptosis in cells based on the western blot, qpcr, and flow cytometry assays. |
2024-04-06 |
2024-04-10 |
Not clear |