| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Elena P Khashchenko, Mikhail Yu Vysokikh, Maria V Marey, Ksenia O Sidorova, Ludmila A Manukhova, Natalya N Shkavro, Elena V Uvarova, Vladimir D Chuprynin, Timur Kh Fatkhudinov, Leila V Adamyan, Gennady T Sukhik. Altered Glycolysis, Mitochondrial Biogenesis, Autophagy and Apoptosis in Peritoneal Endometriosis in Adolescents. International journal of molecular sciences. vol 25. issue 8. 2024-04-27. PMID:38673823. |
samples of plasma and peritoneal fluid exosomes, endometrioid foci and non-affected peritoneum were tested for estrogen receptor (erα/β), hexokinase (hex2), pyruvate dehydrogenase kinase (pdk1), glucose transporter (glut1), monocarboxylate transporters (mct1 and mct2), optic atrophy 1 (opa1, mitochondrial fusion protein), dynamin-related protein 1 (drp1, mitochondrial fission protein), bax, bcl2, beclin1, bnip3, p38 mitogen-activated protein kinase (mapk), hypoxia-inducible factor 1 (hif-1α), mitochondrial voltage-dependent anion channel (vdac) and transforming growth factor (tgfβ) proteins as markers of estrogen signaling, glycolysis rates, mitochondrial biogenesis and damage, apoptosis and autophagy (western-blot and pcr). |
2024-04-27 |
2024-04-29 |
Not clear |
| Elena P Khashchenko, Mikhail Yu Vysokikh, Maria V Marey, Ksenia O Sidorova, Ludmila A Manukhova, Natalya N Shkavro, Elena V Uvarova, Vladimir D Chuprynin, Timur Kh Fatkhudinov, Leila V Adamyan, Gennady T Sukhik. Altered Glycolysis, Mitochondrial Biogenesis, Autophagy and Apoptosis in Peritoneal Endometriosis in Adolescents. International journal of molecular sciences. vol 25. issue 8. 2024-04-27. PMID:38673823. |
the analysis identified higher levels of molecules associated with proliferation (erβ), glycolysis (mct2, pdk1, glut1, hex2, tgfβ and hif-1α), mitochondrial biogenesis (opa1, drp1) and autophagy (p38, beclin1 and bnip3) and decreased levels of apoptosis markers ( |
2024-04-27 |
2024-04-29 |
Not clear |
| Hannah Lawson, James P Holt-Martyn, Vilma Dembitz, Yuka Kabayama, Lydia M Wang, Aarushi Bellani, Samanpreet Atwal, Nadia Saffoon, Jozef Durko, Louie N van de Lagemaat, Azzura L De Pace, Anthony Tumber, Thomas Corner, Eidarus Salah, Christine Arndt, Lennart Brewitz, Matthew Bowen, Louis Dubusse, Derek George, Lewis Allen, Amelie V Guitart, Tsz Kan Fung, Chi Wai Eric So, Juerg Schwaller, Paolo Gallipoli, Donal O'Carroll, Christopher J Schofield, Kamil R Kran. The selective prolyl hydroxylase inhibitor IOX5 stabilizes HIF-1α and compromises development and progression of acute myeloid leukemia. Nature cancer. 2024-04-18. PMID:38637657. |
phd inhibition compromises aml in a hif-1α-dependent manner to disable pro-leukemogenic pathways, re-program metabolism and induce apoptosis, in part via upregulation of bnip3. |
2024-04-18 |
2024-04-21 |
Not clear |
| Qinghua Huang, Xiaoqin Yu, Peijie Fu, Moxin Wu, Xiaoping Yin, Zhiying Chen, Manqing Zhan. Mechanisms and therapeutic targets of mitophagy after intracerebral hemorrhage. Heliyon. vol 10. issue 1. 2024-01-09. PMID:38192843. |
based on studies on mitochondrial autophagy (mitophagy), cellular inflammation, apoptosis, ferroptosis, the bnip3 autophagy gene, pharmacological and other regulatory approaches, and normobaric oxygen (nbo) therapy, this article further explores the neuroprotective role of mitophagy after intracerebral hemorrhage. |
2024-01-09 |
2024-01-10 |
Not clear |
| Chenchen Bian, Shanghong Ji, Rongrong Xue, Lu Zhou, Jian Sun, Hong J. Molecular cloning and characterization of BNIP3 and NIX1/2 and their role in DHA-induced mitophagy and apoptosis in grass carp (Ctenopharyngodon idellus) adipocytes. Gene. 2024-01-07. PMID:38185291. |
molecular cloning and characterization of bnip3 and nix1/2 and their role in dha-induced mitophagy and apoptosis in grass carp (ctenopharyngodon idellus) adipocytes. |
2024-01-07 |
2024-01-10 |
Not clear |
| Chenchen Bian, Shanghong Ji, Rongrong Xue, Lu Zhou, Jian Sun, Hong J. Molecular cloning and characterization of BNIP3 and NIX1/2 and their role in DHA-induced mitophagy and apoptosis in grass carp (Ctenopharyngodon idellus) adipocytes. Gene. 2024-01-07. PMID:38185291. |
b-cell lymphoma-2 and adenovirus e1b 19-kda-interacting protein 3 (bnip3) and bnip3 like (bnip3l or nix) play a vital role in regulating mitophagy and the intrinsic apoptosis in mammals, but their gene characterizations remain unclear in fish. |
2024-01-07 |
2024-01-10 |
Not clear |
| Chenchen Bian, Shanghong Ji, Rongrong Xue, Lu Zhou, Jian Sun, Hong J. Molecular cloning and characterization of BNIP3 and NIX1/2 and their role in DHA-induced mitophagy and apoptosis in grass carp (Ctenopharyngodon idellus) adipocytes. Gene. 2024-01-07. PMID:38185291. |
as typical bh3-only proteins, grass carp bnip3, nix1 and nix2 proteins contain bh3 and c-terminal transmembrane domains for inducing apoptosis. |
2024-01-07 |
2024-01-10 |
Not clear |
| Haifeng Ni, Renhui Liu, Zhen Zhou, Bo Jiang, Bin Wan. Parkin enhances sensitivity of paclitaxel to nasopharyngeal carcinoma by activating BNIP3/NIX-mediated mitochondrial autophagy. The Chinese journal of physiology. vol 66. issue 6. 2023-12-27. PMID:38149563. |
further, bnip3 silencing or overexpression reversed the impacts of parkin upregulation or downregulation on the proliferation and mitochondrial apoptosis of paclitaxel-treated npc cells. |
2023-12-27 |
2023-12-29 |
Not clear |
| Meiyu Zhou, Tianxia Deng, Yonghong Tan, Li Liu, Mingxia Wan. miR-26 inhibits proliferation and promotes apoptosis of multiple myeloma cells by targeting BNIP3. Cellular and molecular biology (Noisy-le-Grand, France). vol 69. issue 11. 2023-12-06. PMID:38054975. |
mir-26 inhibits proliferation and promotes apoptosis of multiple myeloma cells by targeting bnip3. |
2023-12-06 |
2023-12-10 |
Not clear |
| Meiyu Zhou, Tianxia Deng, Yonghong Tan, Li Liu, Mingxia Wan. miR-26 inhibits proliferation and promotes apoptosis of multiple myeloma cells by targeting BNIP3. Cellular and molecular biology (Noisy-le-Grand, France). vol 69. issue 11. 2023-12-06. PMID:38054975. |
this study was carried out to investigate the molecular mechanism of microrna-26 (mir-26) targeting bnip3 to mediate proliferation and apoptosis of multiple myeloma (mm) cells. |
2023-12-06 |
2023-12-10 |
Not clear |
| Meiyu Zhou, Tianxia Deng, Yonghong Tan, Li Liu, Mingxia Wan. miR-26 inhibits proliferation and promotes apoptosis of multiple myeloma cells by targeting BNIP3. Cellular and molecular biology (Noisy-le-Grand, France). vol 69. issue 11. 2023-12-06. PMID:38054975. |
flow cytometry was used to detect the effect of mir-26 expression and bnip3 overexpression on the apoptosis of rpmi8226 cells. |
2023-12-06 |
2023-12-10 |
Not clear |
| Meiyu Zhou, Tianxia Deng, Yonghong Tan, Li Liu, Mingxia Wan. miR-26 inhibits proliferation and promotes apoptosis of multiple myeloma cells by targeting BNIP3. Cellular and molecular biology (Noisy-le-Grand, France). vol 69. issue 11. 2023-12-06. PMID:38054975. |
after up-regulating mir-26 expression, cell viability was significantly decreased (p<0.05), apoptosis rate was significantly increased (p<0.05) dual luciferase reporter experiments confirmed that mir-26 could target bnip3 and negatively regulate the expression of bnip3 (p<0.05). |
2023-12-06 |
2023-12-10 |
Not clear |
| Meiyu Zhou, Tianxia Deng, Yonghong Tan, Li Liu, Mingxia Wan. miR-26 inhibits proliferation and promotes apoptosis of multiple myeloma cells by targeting BNIP3. Cellular and molecular biology (Noisy-le-Grand, France). vol 69. issue 11. 2023-12-06. PMID:38054975. |
overexpression of bnip3 reversed the effect of up-regulation of mir-26 expression on proliferation and apoptosis of rpmi8226 cells. |
2023-12-06 |
2023-12-10 |
Not clear |
| Meiyu Zhou, Tianxia Deng, Yonghong Tan, Li Liu, Mingxia Wan. miR-26 inhibits proliferation and promotes apoptosis of multiple myeloma cells by targeting BNIP3. Cellular and molecular biology (Noisy-le-Grand, France). vol 69. issue 11. 2023-12-06. PMID:38054975. |
up-regulation of mir-26 expression inhibits mm cell proliferation and promotes apoptosis by targeting bnip3. |
2023-12-06 |
2023-12-10 |
Not clear |
| Yijun Suo, Lu Zhang, Yuanhang Ch. IL‑4 alleviates CIRI by suppressing autophagy via the HIF‑1α/Bcl‑2/BNIP3 pathway in rats. Acta neurobiologiae experimentalis. vol 83. issue 3. 2023-10-24. PMID:37874193. |
the nis score, cerebral infarction volume, neuronal apoptosis rate, autophagosome number, lc3ii/lc3i ratio and protein expressions of hif‑1α and bnip3 plummeted, while p62 protein expression sharply rose in il‑4 + 2me2 group relative to those in il‑4 group (p<0.05). |
2023-10-24 |
2023-11-08 |
rat |
| Correction to "Dysregulated pseudogene BNIP3P1 inhibited cell proliferation and promoted cell apoptosis in preeclampsia by acting as a competing endogenous RNA for BNIP3". Environmental toxicology. 2023-09-26. PMID:37750663. |
correction to "dysregulated pseudogene bnip3p1 inhibited cell proliferation and promoted cell apoptosis in preeclampsia by acting as a competing endogenous rna for bnip3". |
2023-09-26 |
2023-10-07 |
Not clear |
| Renfeng Xu, Siting Shen, Defan Wang, Jianqing Ye, Shiting Song, Zhengchao Wang, Zhicao Yu. The role of HIF-1α-mediated autophagy in ionizing radiation-induced testicular injury. Journal of molecular histology. 2023-09-20. PMID:37728670. |
furthermore, the expressions of hif-1α and bnip3 were significantly enhanced in the testis cells of mice irradiated with 2 gy and 5 gy, suggesting the potential role of hif-1α/bnip3-mediated autophagy in the apoptosis of testicular cells induced by ir. |
2023-09-20 |
2023-10-07 |
mouse |
| Xinyong Cai, Pengtao Zou, Lang Hong, Yanmei Chen, Yuliang Zhan, Yuanyuan Liu, Liang Sha. RNA methylation reading protein YTHDF2 relieves myocardial ischemia-reperfusion injury by downregulating BNIP3 via m Human cell. 2023-07-27. PMID:37500815. |
h/r treatment decreased cell viability and p62 and sod levels while elevating cell apoptosis, the levels of ck-mb, ctni, ldh, mda, ros, and lc3 ii/lc3 i, the number of autophagosomes, and the co-localization of lc3 and tomm20 in cardiomyocytes, which were neutralized by downregulating bnip3 or upregulating ythdf2. |
2023-07-27 |
2023-08-14 |
rat |
| Pingping Xiao, Xuyan Chen, Zhigao Dong, Wei Fan, Yongquan Chen, Junnan Su, Qingqing Wang, Lili M. BNIP3 overexpression may promote myeloma cell apoptosis by enhancing sensitivity to bortezomib via the p38 MAPK pathway. Hematology (Amsterdam, Netherlands). vol 28. issue 1. 2023-07-04. PMID:37401850. |
bnip3 overexpression may promote myeloma cell apoptosis by enhancing sensitivity to bortezomib via the p38 mapk pathway. |
2023-07-04 |
2023-08-14 |
Not clear |
| Ruifang Chi, Chanjuan Chai, Gaizhen Liu, Huili Cao, Bin Yan. Chronic intermittent hypoxia-induced BNIP3 expression mitigates contractile dysfunction and myocardial injury in animal and cell model via modulating autophagy. Human cell. 2023-01-10. PMID:36627546. |
knockout of bnip3 significantly aggravated the impairment in cardiac function, apoptosis, oxidative stress, and hypertrophy of cih rats, while significantly reducing autophagy. |
2023-01-10 |
2023-08-14 |
rat |