| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jingshu Hong, Yue Li, Lei Chen, Dengyang Han, Yitong Li, Xinning Mi, Kaixi Liu, Qian Wang, Yanan Song, Taotao Liu, Ning Yang, Yajie Liu, Zhengqian Li, Xiangyang Gu. A53T α-synuclein mutation increases susceptibility to postoperative delayed neurocognitive recovery via hippocampal Ang-(1-7)/MasR axis. Biochemical pharmacology. 2024-05-05. PMID:38705534. |
we respectively examined molecular changes at 6 h, 1 day, and 2 days after partial hepatectomy and observed that cognitive changes were accompanied by weakened angiotensin-(1-7)/mas receptor [ang-(1-7)/masr] axis, increased alpha-synuclein (α-syn) expression and phosphorylation, decreased methylated protein phosphatase-2a (me-pp2a), and prompted microglia m1 polarization and neuronal apoptosis in the hippocampus at 1 day after surgery. |
2024-05-05 |
2024-05-08 |
mouse |
| Majid Motaghinejad, Manijeh Motevalian, Fatemeh Babalouei, Mohammad Abdollahi, Mansour Heidari, Zahra Madj. Retraction Notice to "Possible involvement of CREB/BDNF signaling pathway in neuroprotective effects of topiramate against methylphenidate induced apoptosis, oxidative stress and inflammation in hippocampus of rats: Molecular, biochemical and histological evidences" [Brain. Res. Bull. 132 (2017) 82-98]. Brain research bulletin. 2024-04-28. PMID:38679545. |
retraction notice to "possible involvement of creb/bdnf signaling pathway in neuroprotective effects of topiramate against methylphenidate induced apoptosis, oxidative stress and inflammation in hippocampus of rats: molecular, biochemical and histological evidences" [brain. |
2024-04-28 |
2024-05-01 |
rat |
| Xuerui Kong, Gaohe Dai, Zhong Zeng, Yi Zhang, Jiarong Gu, Teng Ma, Nina Wang, Jinhai Gu, Yin Wan. Integrating Proteomics and Transcriptomics Reveals the Potential Pathways of Hippocampal Neuron Apoptosis in Dravet Syndrome Model Mice. International journal of molecular sciences. vol 25. issue 8. 2024-04-27. PMID:38674042. |
integrating proteomics and transcriptomics reveals the potential pathways of hippocampal neuron apoptosis in dravet syndrome model mice. |
2024-04-27 |
2024-04-29 |
mouse |
| Hamed Ghazvini, Fatemeh Tirgar, Mehdi Khodamoradi, Seyedeh Masoumeh Seyedhosseini Tamijani, Saba Niknamfar, Esmaeil Akbari, Mohammad Nekahi, Nabiollah Tarjani, Hossein Ghalehnoei, Motahareh Rouhi Ardeshir. Investigating Facilitatory Effects of Lithium on Methamphetamine-induced Spatial Memory Impairments in Rat. Basic and clinical neuroscience. vol 14. issue 5. 2024-04-17. PMID:38628835. |
in current study the effects of lithium on spatial memory, hippocampal apoptosis and brain edema in meth-exposed rats are investigated. |
2024-04-17 |
2024-04-19 |
rat |
| Yuhai Xu, Xin Xin, Tianzhu Ta. Decoding the Neurotoxic Effects of Propofol: Insights into the RARα-Snhg1-Bdnf Regulatory Cascade. American journal of physiology. Cell physiology. 2024-04-15. PMID:38618701. |
the findings draw a clear link between propofol-induced neurotoxicity and the amplification of rar signaling pathways, impacting hippocampal development and apoptosis and leading to increased rarα and snhg1 and decreased bdnf. |
2024-04-15 |
2024-04-17 |
Not clear |
| Xinbo Ma, Yang Liu, Bo Ding, Siqi Lu, Bangyao Ni, Yuting Chen, Liu Yang, Yanan Liu, Yuchen Zhang, Yuxi Wang, Yanmei Yang, Xiaona Li. Anthocyanins from blueberry ameliorated arsenic-induced memory impairment, oxidative stress, and mitochondrial-biosynthesis imbalance in rat hippocampal neurons. Cellular signalling. 2024-04-15. PMID:38621470. |
arsenic exposure resulted in elevated levels of oxidative stress, decreased antioxidant capacity and increased apoptosis in rat hippocampal brain tissue and mitochondria. |
2024-04-15 |
2024-04-18 |
rat |
| Xiyong Xiang, Siyu Xia, Shan Li, Yirong Zeng, Lixuan Wang, Yan Zho. Study on the role and mechanism of Tan IIA in Alzheimer's disease based on CREB-BDNF-TrkB pathway. Neuroscience letters. 2024-04-14. PMID:38616003. |
the results of the water maze experiment showed that after tan iia treatment, the escape latency of ad rats was shortened and the number of platform crossings increased; in the new object recognition experiment, the discrimination index of ad rats significantly increased after treatment; nissl staining and tunel staining results showed that tan iia increased the number of surviving neurons in the hippocampus of cognitively impaired rats and reduced neuronal apoptosis; bielschowsky silver staining results showed that tan iia reduced neurofibrillary tangles (nfts) in the ad rats; tan iia can reduce the inflammatory response and oxidative stress reaction in the hippocampus of ad rats, and at the same time reduce the activity of acetylcholinesterase. |
2024-04-14 |
2024-04-17 |
rat |
| Xiyong Xiang, Siyu Xia, Shan Li, Yirong Zeng, Lixuan Wang, Yan Zho. Study on the role and mechanism of Tan IIA in Alzheimer's disease based on CREB-BDNF-TrkB pathway. Neuroscience letters. 2024-04-14. PMID:38616003. |
these data suggest that tan iia may upregulate the expression of the creb-bdnf-trkb signaling pathway in the hippocampus of brain tissue, produce anti-neuroinflammatory, antioxidant stress, inhibit neuronal apoptosis effects, and improve cholinergic neurotransmitter disorder induced by stz, reduce the neuronal damage and learning and memory impairment caused by stz in rats, and improve the cognitive function of rats. |
2024-04-14 |
2024-04-17 |
rat |
| Daniela Giovannini, Francesca Antonelli, Arianna Casciati, Cinzia De Angelis, Maria Denise Astorino, Giulia Bazzano, Emiliano Fratini, Alessandro Ampollini, Monia Vadrucci, Evaristo Cisbani, Paolo Nenzi, Luigi Picardi, Anna Saran, Carmela Marino, Mariateresa Mancuso, Concetta Ronsivalle, Simonetta Pazzagli. Comparing the effects of irradiation with protons or photons on neonatal mouse brain: Apoptosis, oncogenesis and hippocampal alterations. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 2024-04-13. PMID:38614282. |
comparing the effects of irradiation with protons or photons on neonatal mouse brain: apoptosis, oncogenesis and hippocampal alterations. |
2024-04-13 |
2024-04-16 |
mouse |
| Fahaid H Al-Hashem, Salah O Bashir, Amal F Dawood, Moutasem S Aboonq, Ismaeel Bin-Jaliah, Abdulaiziz M Al-Garni, Mohamed D Mors. Vanillylacetone attenuates cadmium chloride-induced hippocampal damage and memory loss through up-regulation of nuclear factor erythroid 2-related factor 2 gene and protein expression. Neural regeneration research. vol 19. issue 12. 2024-04-10. PMID:38595292. |
additionally, vanillylacetone markedly decreased the hippocampal tissue levels of inflammatory biomarkers (interleukin-6, tumor necrosis factor-α, intracellular cell adhesive molecules) and apoptosis biomarkers (bax and cleaved caspase-3). |
2024-04-10 |
2024-04-12 |
rat |
| Zhiheng Zhang, Wenhan Liu, Meilun Shen, Xiangying Ma, Rouqian Li, Xiaodi Jin, Hui Bai, Li Ga. Correction to: Protective Effect of GM1 Attenuates Hippocampus and Cortex Apoptosis After Ketamine Exposure in Neonatal Rat via PI3K/AKT/GSK3β Pathway. Molecular neurobiology. 2024-04-09. PMID:38592588. |
correction to: protective effect of gm1 attenuates hippocampus and cortex apoptosis after ketamine exposure in neonatal rat via pi3k/akt/gsk3β pathway. |
2024-04-09 |
2024-04-11 |
rat |
| Wen Zhang, Yang Liu, Zhicun Wang, Shuyi He, Wenqi Liu, Yu Wu, Li Yang, Cheng Hu, Yunbing Wan. Remodeling brain pathological microenvironment to lessen cerebral ischemia injury by multifunctional injectable hydrogels. Journal of controlled release : official journal of the Controlled Release Society. 2024-04-06. PMID:38582336. |
the in vitro results exhibited the multifunctional hydrogel scavenged oxygen-glucose deprivation (ogd)-induced free radical, rescued the mitochondrial function, and maintained the survival and function of neurons, hence reducing neuronal apoptosis and neuroinflammation, consequently relieving ischemia injury in hippocampal neurons cell line (ht22). |
2024-04-06 |
2024-04-10 |
rat |
| Benjamin Ongnok, Nanthip Prathumsap, Titikorn Chunchai, Patcharapong Pantiya, Busarin Arunsak, Nipon Chattipakorn, Siriporn C Chattipakor. Nicotinic and Muscarinic Acetylcholine Receptor Agonists Counteract Cognitive Impairment in a Rat Model of Doxorubicin-Induced Chemobrain via Attenuation of Multiple Programmed Cell Death Pathways. Molecular neurobiology. 2024-04-03. PMID:38568417. |
dox insult also mediated hyperphosphorylation of tau and simultaneously induced various pcd, including apoptosis, necroptosis, and pyroptosis in the hippocampus. |
2024-04-03 |
2024-04-05 |
rat |
| Ming Wang, Binyuan Xu, Yangmei Xie, Ge Yao, Yinghui Che. Mir155hg Accelerates Hippocampal Neuron Injury in Convulsive Status Epilepticus by Inhibiting Microglial Phagocytosis. Neurochemical research. 2024-03-30. PMID:38555337. |
he and tunel staining results showed that mir155hg knockdown suppressed the hippocampal neuron loss and apoptosis followed cse. |
2024-03-30 |
2024-04-02 |
rat |
| Beydolah Shahouzehi, Yaser Masoumi-Ardakani, Hossein Fallah, Soheil Aminizade. Evaluation of the effect of Exercise Trainings and CGRP receptor antagonist (BIBN 4096) on mitochondrial dynamic in the hippocampus of male Wistar rats. Neuroscience letters. 2024-03-29. PMID:38552868. |
the purpose of the present study is to evaluate the effect of six weeks of high-intensity interval training (hiit) and endurance training (et) with calcitonin gene-related peptide (cgrp) receptor antagonist on the expression of genes involved in mitochondrial dynamics and apoptosis in hippocampal tissue of male wistar rats. |
2024-03-29 |
2024-04-01 |
rat |
| Mubeen A Ansari, Aishah Al-Jarallah, Muddanna S Rao, Ahmed Babiker, Khaled Bensalama. Upregulation of NADPH-oxidase, inducible nitric oxide synthase and apoptosis in the hippocampus following impaired insulin signaling in the rats: Development of sporadic Alzheimer's disease. Brain research. 2024-03-29. PMID:38552936. |
upregulation of nadph-oxidase, inducible nitric oxide synthase and apoptosis in the hippocampus following impaired insulin signaling in the rats: development of sporadic alzheimer's disease. |
2024-03-29 |
2024-04-01 |
rat |
| Paola Rodríguez-Quintero, Moisés Rubio-Osornio, Eric Uribe, Wilhelm Moreno, Luis A Marín-Castañeda, Zayra Morales, Alonso Portila, David Vázquez, Carmen Rubi. Exposure to Ozone Downregulates Bcl-2 and Increases Executing Caspases-3 and -8 in the Hippocampus, Frontal Cortex, and Cerebellum of Rats. Cureus. vol 16. issue 2. 2024-03-22. PMID:38516464. |
conclusions this study demonstrates that acute exposure to 1 ppm of ozone can trigger neuronal apoptosis in the frontal cortex, hippocampus, and cerebellum of rats, primarily through the activation of the extrinsic apoptosis pathway via caspase-8 and caspase-3. |
2024-03-22 |
2024-03-24 |
rat |
| Vaibhav Gupta, Rashmi Srivastav. Ashwagandha Diminishes Hippocampal Apoptosis Induced by Microwave Radiation by Acetylcholinesterase Dependent Neuro-Inflammatory Pathway in Male Coturnix coturnix Japonica. Neurochemical research. 2024-03-20. PMID:38506951. |
ashwagandha diminishes hippocampal apoptosis induced by microwave radiation by acetylcholinesterase dependent neuro-inflammatory pathway in male coturnix coturnix japonica. |
2024-03-20 |
2024-03-23 |
cat |
| Vaibhav Gupta, Rashmi Srivastav. Ashwagandha Diminishes Hippocampal Apoptosis Induced by Microwave Radiation by Acetylcholinesterase Dependent Neuro-Inflammatory Pathway in Male Coturnix coturnix Japonica. Neurochemical research. 2024-03-20. PMID:38506951. |
mwr also caused a significant decline in the nissil substances in the hippocampus region of brain indicating neurodegeneration through oxidative stress mediated hippocampal apoptosis. |
2024-03-20 |
2024-03-23 |
cat |
| Badrah Alghamdi, Emad H M Hassanein, Saif A Alharthy, Reem M Farsi, Steve Harake. Vinpocetine attenuates methotrexate-induced hippocampal intoxication via Keap-1/Nrf2, NF-κB/AP-1, and apoptotic pathways in rats. Drug and chemical toxicology. 2024-03-20. PMID:38508707. |
additionally, vnp attenuated apoptosis by reducing hippocampal bax levels while increasing bcl2 levels in mtx-intoxicated rats. |
2024-03-20 |
2024-03-23 |
rat |