| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mariana Rae, Ivone Gomes, Lidia Emmanuela Wiazowski Spelta, Alexis Bailey, Tania Marcourakis, Lakshmi Devi, Rosana Camarin. Environmental Enrichment Enhances Ethanol Preference Over Social Reward in Male Swiss Mice: involvement of oxytocin-dopamine interactions. Neuropharmacology. 2024-05-05. PMID:38705568. |
environmental enrichment enhances ethanol preference over social reward in male swiss mice: involvement of oxytocin-dopamine interactions. |
2024-05-05 |
2024-05-08 |
mouse |
| Pablo Berríos-Cárcamo, Sarah Núñez, Justine Castañeda, Javiera Gallardo, María Rosa Bono, Fernando Ezque. Two-Month Voluntary Ethanol Consumption Promotes Mild Neuroinflammation in the Cerebellum but Not in the Prefrontal Cortex, Hippocampus, or Striatum of Mice. International journal of molecular sciences. vol 25. issue 8. 2024-04-27. PMID:38673763. |
chronic ethanol exposure often triggers neuroinflammation in the brain's reward system, potentially promoting the drive for ethanol consumption. |
2024-04-27 |
2024-04-29 |
mouse |
| Shelby Travaglianti, Ahmed Alotaibi, Woonyen Wong, Magid Abou-Gharbia, Wayne Childers, Youssef Sar. Effects of novel GLT-1 modulator, MC-100093, on neuroinflammatory and neurotrophic biomarkers in mesocorticolimbic brain regions of male alcohol preferring rats exposed chronically to ethanol. Brain research bulletin. 2024-04-03. PMID:38570076. |
chronic ethanol consumption can lead to increased extracellular glutamate concentrations in key reward brain regions, such as medial prefrontal cortex (mpfc) and nucleus accumbens (nac), and consequently leading to oxidative stress and neuroinflammation. |
2024-04-03 |
2024-04-06 |
rat |
| Kathleen G Bryant, Binay Singh, Jacqueline M Barke. Sex and individual differences in the effect of chronic low-dose ethanol on behavioral strategy selection. Alcohol, clinical & experimental research. vol 48. issue 1. 2024-01-11. PMID:38206280. |
low levels of ethanol drinking may promote the formation of inflexible, habitual reward seeking, but this may depend on the timing of ethanol exposure in relation to learning. |
2024-01-11 |
2024-01-13 |
Not clear |
| Anna Loftén, Louise Adermark, Mia Ericson, Bo Söderpal. Regulation of ethanol-mediated dopamine elevation by glycine receptors located on cholinergic interneurons in the nucleus accumbens. Addiction biology. vol 28. issue 12. 2023-11-29. PMID:38017639. |
alcohol use disorder is one of the major psychiatric disorders worldwide, and there are many factors and effects contributing to the disorder, for example, the experience of ethanol reward. |
2023-11-30 |
2023-12-07 |
rat |
| Anna Loftén, Louise Adermark, Mia Ericson, Bo Söderpal. Regulation of ethanol-mediated dopamine elevation by glycine receptors located on cholinergic interneurons in the nucleus accumbens. Addiction biology. vol 28. issue 12. 2023-11-29. PMID:38017639. |
alcohol use disorder is one of the major psychiatric disorders worldwide, and there are many factors and effects contributing to the disorder, for example, the experience of ethanol reward. |
2023-11-29 |
2023-12-07 |
rat |
| Andrew D Chapp, Chinonso A Nwakama, Andréa R Collins, Paul G Mermelstein, Mark J Thoma. Physiological acetic acid concentrations from ethanol metabolism stimulate accumbens shell medium spiny neurons via NMDAR activation in a sex-dependent manner. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2023-10-16. PMID:37845488. |
in this study, we investigated sex-specific metabolism of ethanol (1, 2, and 4 g/kg) to acetic acid in vivo to guide electrophysiology experiments in the accumbens shell (nacsh), a key node in the mammalian reward circuit. |
2023-10-16 |
2023-11-08 |
Not clear |
| Andrew D Chapp, Chinonso A Nwakama, Andréa R Collins, Paul G Mermelstein, Mark J Thoma. Physiological acetic acid concentrations from ethanol metabolism stimulate accumbens shell medium spiny neurons via NMDAR activation in a sex-dependent manner. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2023-10-16. PMID:37845488. |
these findings suggest a novel nmdar-dependent mechanism by which the ethanol metabolite, acetic acid, may influence neurophysiological effects in a key reward circuit in the brain from ethanol consumption. |
2023-10-16 |
2023-11-08 |
Not clear |
| Matthew M Ford, Brianna E George, Victor S Van Laar, Katherine M Holleran, Jerusha Naidoo, Piotr Hadaczek, Lauren E Vanderhooft, Emily G Peck, Monica H Dawes, Kousaku Ohno, John Bringas, Jodi L McBride, Lluis Samaranch, John R Forsayeth, Sara R Jones, Kathleen A Grant, Krystof S Bankiewic. GDNF gene therapy for alcohol use disorder in male non-human primates. Nature medicine. 2023-08-14. PMID:37580533. |
repeated ethanol use induces dopaminergic signaling neuroadaptations in ventral tegmental area (vta) neurons of the mesolimbic reward pathway, and sustained dysfunction of reward circuitry is associated with return to drinking behavior. |
2023-08-14 |
2023-09-07 |
human |
| Laura L Giacometti, Christine M Side, Kelsey Chandran, Sam Stine, Lauren A Buck, Rebecca M Wenzel-Rideout, Jacqueline M Barke. Consequences of adolescent ethanol exposure on nondrug reward seeking in adulthood in male and female mice. Alcohol (Hanover, York County, Pa.). 2023-07-12. PMID:37438117. |
consequences of adolescent ethanol exposure on nondrug reward seeking in adulthood in male and female mice. |
2023-07-12 |
2023-08-14 |
mouse |
| Kathleen G Bryant, Mitchell A Nothem, Lauren A Buck, Binay Singh, Sana Amin, Christina M Curran-Alfaro, Jacqueline M Barke. A history of low-dose ethanol shifts the role of ventral hippocampus during reward seeking in male mice. eNeuro. 2023-05-08. PMID:37156611. |
a history of low-dose ethanol shifts the role of ventral hippocampus during reward seeking in male mice. |
2023-05-08 |
2023-08-14 |
mouse |
| Kathleen G Bryant, Mitchell A Nothem, Lauren A Buck, Binay Singh, Sana Amin, Christina M Curran-Alfaro, Jacqueline M Barke. A history of low-dose ethanol shifts the role of ventral hippocampus during reward seeking in male mice. eNeuro. 2023-05-08. PMID:37156611. |
as the ventral hippocampus (vhpc) is sensitive to disruption by higher doses of chronic ethanol and tracks reward-related information, we hypothesized that this region is impacted by low-dose ethanol and, further, that manipulating vhpc activity would alter reward motivation. |
2023-05-08 |
2023-08-14 |
mouse |
| Renato Elias Moreira-Júnior, Mauro Andrade de Freitas Guimarães, Miguel Etcheverria da Silva, Tatiani Uceli Maioli, Ana Maria Caetano Faria, Ana Lúcia Brunialti-Godar. Animal model for high consumption and preference of ethanol and its interplay with high sugar and butter diet, behavior, and neuroimmune system. Frontiers in nutrition. vol 10. 2023-04-17. PMID:37063320. |
in this regard, there is a belief that, in the striatum, an integrating region of the brain reward system, the interaction of the immune response and the transcriptional profile of the lrrk2 gene that is associated with loss of control and addiction to ethanol may influence the alcohol consumption and preference. |
2023-04-17 |
2023-08-14 |
Not clear |
| Alberto Nascè, Zoltan Patak. [What is the relationship between alcohol and obesity?] Revue medicale suisse. vol 19. issue 819. 2023-03-23. PMID:36950784. |
ethanol must be considered as an orexigenic molecule, acting on the cerebral regulation of hunger and satiety and on the mesolimbic reward system. |
2023-03-23 |
2023-08-14 |
Not clear |
| Hillary A Wadsworth, Elizabeth Q Anderson, Benjamin M Williams, Joakim W Ronström, Janna K Moen, Anna M Lee, J Michael McIntosh, Jie Wu, Jordan T Yorgason, Scott C Steffense. Role of α6-Nicotinic Receptors in Alcohol-Induced GABAergic Synaptic Transmission and Plasticity to Cholinergic Interneurons in the Nucleus Accumbens. Molecular neurobiology. 2023-02-21. PMID:36802012. |
the prevailing view is that enhancement of dopamine (da) transmission in the mesolimbic system, consisting of da neurons in the ventral tegmental area (vta) that project to the nucleus accumbens (nac), underlies the reward properties of ethanol (etoh) and nicotine (nic). |
2023-02-21 |
2023-08-14 |
mouse |
| Milagros Galán-Llario, María Rodríguez-Zapata, Teresa Fontán-Baselga, Esther Gramage, Marta Vicente-Rodríguez, José María Zapico, Beatriz de Pascual-Teresa, Amy W Lasek, Gonzalo Herradó. Inhibition of RPTPβ/ζ reduces chronic ethanol intake in adolescent mice and modulates ethanol effects on hippocampal neurogenesis and glial responses in a sex-dependent manner. Neuropharmacology. 2023-01-27. PMID:36706907. |
pleiotrophin (ptn) is a cytokine that modulates ethanol drinking and reward and regulates glial responses in different contexts. |
2023-01-27 |
2023-08-14 |
mouse |
| Mia E Radevski, Mark A Prendergast, Michael T Bardo, Chana K Akin. PT150 blocks the rewarding properties of ethanol and attenuates ethanol-induced reduction of egg laying in Coturnix quail. Psychopharmacology. 2023-01-06. PMID:36607385. |
however, the effect of blocking corticosterone receptors on ethanol reward has yet to be investigated. |
2023-01-06 |
2023-08-14 |
Not clear |
| Laura L Giacometti, Lauren A Buck, Jacqueline M Barke. Estrous cycle and hormone regulation of stress-induced reinstatement of reward seeking in female mice. Addiction neuroscience. vol 4. 2022-12-21. PMID:36540408. |
seventy-two hours after the final ethanol exposure, food-restricted mice began training in a conditioned place preference paradigm (cpp) for a food reward, followed by extinction training. |
2022-12-21 |
2023-08-14 |
mouse |
| Honoreé W Brewton, Stacey L Robinson, Todd E Thiel. Astrocyte Expression in the Extended Amygdala of C57BL/6J Mice is Sex-Dependently Affected by Chronic Intermittent and Binge-Like Ethanol Exposure. Alcohol (Fayetteville, N.Y.). 2022-12-20. PMID:36539069. |
the basolateral amygdala (bla), central amygdala (cea), and bed nucleus of the stria terminalis (bnst) are brain regions that process stress, anxiety, and reward; they are also implicated in modulating ethanol intake. |
2022-12-20 |
2023-08-14 |
mouse |
| Hasan Alhaddad, Woonyen Wong, Magid Abou-Gharbia, Wayne Childers, Edward Melenski, Richard L Bell, Youssef Sar. Effects of a Novel Beta Lactam Compound, MC-100093, on the Expression of Glutamate Transporters/Receptors and Ethanol Drinking Behavior of Alcohol-Preferring Rats. The Journal of pharmacology and experimental therapeutics. vol 383. issue 3. 2022-11-17. PMID:36153003. |
chronic ethanol exposure affects the glutamatergic system in several brain reward regions including the nucleus accumbens (nac). |
2022-11-17 |
2023-11-20 |
rat |