| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sedef Ziyanok-Demirta. Therapeutic potentials of Hibiscus trionum: Antioxidant, anti-lipid peroxidative, hypoglycemic, and hepatoprotective effects in type 1 diabetic rats. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 175. 2024-04-27. PMID:38677247. |
serum total cholesterol (tc), triglyceride (tg), aspartate aminotransferase (ast), and alanine aminotransferase (alt) levels were evaluated. |
2024-04-27 |
2024-04-30 |
rat |
| Sedef Ziyanok-Demirta. Therapeutic potentials of Hibiscus trionum: Antioxidant, anti-lipid peroxidative, hypoglycemic, and hepatoprotective effects in type 1 diabetic rats. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 175. 2024-04-27. PMID:38677247. |
moreover, the diabetic group also showed increased levels of mda, tc, tg, ast, and alt, along with reduced insulin levels, compared to the control group. |
2024-04-27 |
2024-04-30 |
rat |
| Seung Tae Im, Heejoo Kang, Jusang Kim, Song-Rae Kim, Kil-Nam Kim, Seung-Hong Le. Narirutin-Rich Celluclast Extract from Mandarin ( International journal of molecular sciences. vol 25. issue 8. 2024-04-27. PMID:38674060. |
mpce also reduced triglyceride (tg), alanine transaminase (alt), aspartate transaminase (ast), and leptin contents in the serum of hfd-fed mice. |
2024-04-27 |
2024-04-29 |
mouse |
| Xixi Zeng, Ling Chen, Bo Zhen. Extrusion and chlorogenic acid treatment increase the ordered structure and resistant starch levels in rice starch with amelioration of gut lipid metabolism in obese rats. Food & function. 2024-04-16. PMID:38623646. |
compared to a physical mixture of starch and chlorogenic acid (cga + s), cga-es showed a more potent effect in alleviating lipid metabolism disorders, manifesting as reduced levels of blood glucose, serum total cholesterol (tc), triglycerides (tg), aspartate aminotransferase (ast), alanine transaminase (alt) and alkaline phosphatase (akp), as well as body weight. |
2024-04-16 |
2024-04-18 |
rat |
| Zhi Qin, Min Zho. [Tanshinone Ⅱ_A inhibits ferroptosis via Nrf2 signaling pathway to protect liver in rats of non-alcoholic fatty liver disease]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 49. issue 6. 2024-04-15. PMID:38621946. |
a biochemical analyzer was used to measure the content of aspartate aminotransferase(ast), alaninl aminotransferase(alt), total cholesterol(tc), and triglycerides(tg). |
2024-04-15 |
2024-04-18 |
rat |
| Zhi Qin, Min Zho. [Tanshinone Ⅱ_A inhibits ferroptosis via Nrf2 signaling pathway to protect liver in rats of non-alcoholic fatty liver disease]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 49. issue 6. 2024-04-15. PMID:38621946. |
the result showed that tsⅡ_a significantly reduced the content of mda, ast, alt, tc, and tg in the serum, increased the activity of sod, decreased the apoptosis rate, lipid deposition, ros, and iron deposition in the liver tissue, up-regulated the expression of nrf2, ho-1, fsp1, gpx, and bcl-2, and inhibited the expression of bax in the liver tissue of nafld rats. |
2024-04-15 |
2024-04-18 |
rat |
| Marcela C Sena, Fábio C Sterzelecki, Paola Fabiana F Gomes, Helen Cristiane A Souza, Nuno Filipe A Correia de Melo, J Natividade, B Baldisserotto, Glauber David A Palheta, Simone do Socorro D Santo. Maximum storage time of refrigerated blood and frozen plasma samples from tambaqui, Colossoma macropomum. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. 2024-04-11. PMID:38604560. |
the parameters analyzed were hematocrit (ht), hemoglobin content (hb), total erythrocytes (rbc), total (wbc) and differential leukocytes, total thrombocytes (tc), glucose content (glc), total protein (tp), triglyceride content (tg), total cholesterol (cot), and the activities of alanine aminotransferase (alt) and aspartate aminotransferase (ast). |
2024-04-11 |
2024-04-14 |
Not clear |
| Mengyun Dong, Tianliang Zhang, Xueli Liang, Xinyi Cheng, Fuyan Shi, Hang Yuan, Fengxiang Zhang, Qiqi Jiang, Xia Wan. Sesamin alleviates lipid accumulation induced by oleic acid via PINK1/Parkin-mediated mitophagy in HepG2 cells. Biochemical and biophysical research communications. vol 708. 2024-03-26. PMID:38531220. |
cell viability was evaluated using the cck-8 method, and triglycerides (tg), total cholesterol (tc), high-density lipoprotein cholesterol (hdl-c), low-density lipoprotein, cholesterol (ldl-c), alanine aminotransferase (alt), along with aspartate aminotransferase (ast) were assessed by oil red o staining, transmission electron microscopy (tem), and biochemical kits to investigate the lipid-lowering effects of sesamin. |
2024-03-26 |
2024-03-29 |
Not clear |
| Jian Song, Bo-Feng Qin, Jin-Jin Zhang, Qi-Yuan Feng, Guan-Cheng Liu, Gui-Yun Zhao, Hai-Ming Su. Regulation of the Nur77-P2X7r Signaling Pathway by Nodakenin: A Potential Protective Function against Alcoholic Liver Disease. Molecules (Basel, Switzerland). vol 29. issue 5. 2024-03-13. PMID:38474588. |
in vivo, histopathological alterations were markedly alleviated by nk, accompanied by reductions in serum triglyceride (tg), aspartate aminotransferase (ast), and alanine aminotransferase (alt) levels and the modulation of lipin-1, srebp1, and nur77 levels in comparison to the etoh-exposed group ( |
2024-03-13 |
2024-03-15 |
mouse |
| Weiwen Lai, Shipeng Zhou, Yan Bai, Qishi Che, Hua Cao, Jiao Guo, Zhengquan S. Glucosamine attenuates alcohol-induced acute liver injury via inhibiting oxidative stress and inflammation. Current research in food science. vol 8. 2024-02-29. PMID:38420347. |
the results showed that glc can significantly inhibit the abnormal increase of aspartate aminotransferase (ast), alanine aminotransferase (alt), alkaline phosphatase (alp), lactate dehydrogenase (ldh), triglycerides (tg), total cholesterol (tc), very low density lipoprotein (vldl), low-density lipoprotein cholesterol (ldl-c), and can significantly improve the level of high-density lipoprotein cholesterol (hdl-c). |
2024-02-29 |
2024-03-02 |
mouse |
| Yujuan Yu, Fumao Zeng, Peiheng Han, Li Zhang, Ling Yang, Feng Zhou, Qing Liu, Zheng Rua. Dietary chlorogenic acid alleviates high-fat diet-induced steatotic liver disease by regulating metabolites and gut microbiota. International journal of food sciences and nutrition. 2024-02-23. PMID:38389248. |
in comparison to the hf group, the tc (total cholesterol), tg (total triglycerides), ldl-c (low-density lipoprotein cholesterol), ast (aspartate aminotransferase) and alt (alanine transaminase) levels were reduced after cga supplement. |
2024-02-23 |
2024-02-25 |
mouse |
| Ruofan Liu, Cuiyuan Mo, Xuetuan Wei, Aimin M. Hepatoprotective Effect of Annulohypoxylon stygium Melanin on Acute Alcoholic Liver Injury in Mice. Applied biochemistry and biotechnology. 2024-02-21. PMID:38381310. |
it was able to significantly decrease the activities of aspartate aminotransferase (ast) and alanine aminotransferase (alt), the contents of triglyceride (tg) and total cholesterol (tc) in mice. |
2024-02-21 |
2024-02-23 |
mouse |
| Guojun Wan, Zengli Zhang, Jingsi Chen, Mei Li, Jiafu L. GenX caused liver injury and potential hepatocellular carcinoma of mice via drinking water even at environmental concentration. Environmental pollution (Barking, Essex : 1987). 2024-02-16. PMID:38365076. |
genx was found to cause a dose-dependent increase in the serum levels of alanine aminotransferase (alt), aspartate aminotransferase (ast), total cholesterol (tc), and triglyceride (tg). |
2024-02-16 |
2024-02-19 |
mouse |
| Penghui Zhao, Yinchen Hou, Xinyang Chen, Mingyi Zhang, Zheyuan Hu, Lishui Chen, Jihong Huan. High Fischer Ratio Oligopeptides of Gluten Alleviate Alcohol-Induced Liver Damage by Regulating Lipid Metabolism and Oxidative Stress in Rats. Foods (Basel, Switzerland). vol 13. issue 3. 2024-02-10. PMID:38338571. |
following intervention, the levels of serum total cholesterol (tc), triglyceride (tg), alanine aminotransferase (alt), aspartate aminotransferase (ast), and hepatic malondialdehyde (mda) in the rats significantly decreased ( |
2024-02-10 |
2024-02-12 |
rat |
| Ik-Rak Jung, Rexford S Ahima, Sangwon F Ki. Time-Restricted Feeding Ameliorates Methionine-Choline Deficient Diet-Induced Steatohepatitis in Mice. International journal of molecular sciences. vol 25. issue 3. 2024-02-10. PMID:38338668. |
here, we show that trf alleviated markers of nash, i.e., reduced hepatic steatosis, liver triglycerides (tg), serum alanine transaminase (alt) and aspartate aminotransferase (ast), inflammation, and fibrosis in mcdd mice. |
2024-02-10 |
2024-02-12 |
mouse |
| Suli He, Chao Yan, Min Wu, Haiyan Peng, Ren Li, Jian Wan, Xin Ye, Hongmao Zhang, Shumao Din. Dibutyl phthalate adsorbed on multi-walled carbon nanotubes can aggravate liver injury in mice via the Jak2/STAT3 pathway. Toxicology and industrial health. 2024-01-29. PMID:38285958. |
additionally, alanine aminotransferase (alt) and aspartate aminotransferase (ast) were elevated in the liver, and glucose, pyruvate, triglyceride (tg), and total cholesterol (t-cho) were significantly reduced, suggesting compromised liver function. |
2024-01-29 |
2024-02-01 |
mouse |
| Wang-Zhen-Zu Liu, Xiao-Jing Qian, Jia-Qi Zhang, Kun Liang, Cheng Hu, Xin-Hong Wan. [Lipid-lowering effect of drug pair Scutellariae Radix-Coptidis Rhizoma based on lipomics]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 48. issue 24. 2024-01-11. PMID:38212031. |
the results showed that compared with the control group, the model group showed increased levels of alanine aminotransferase(alt), aspartate aminotransferase(ast), total cholesterol(tc), triglyceride(tg), and low-density lipoprotein cholesterol(ldl-c)(p<0.01), and decreased levels of γ-glutamyl transferase(γ-gt) and high-density lipoprotein cholesterol(hdl-c)(p<0.01), which were significantly recovered by the intervention of sr-cr. |
2024-01-11 |
2024-01-14 |
rat |
| Mahta Keshtkaran, Shahin Hassanpour, Kaveh Parvandar Asadollahi, Morteza Zendehde. Effects of in ovo injection of the L-carnosine on physiological indexes of neonatal broiler chicken. Poultry science. vol 103. issue 3. 2024-01-10. PMID:38198911. |
the in ovo injection of l-carnosine (25 and 50 µg) on d 7 and 18 of incubation resulted in a significant decrease in the levels of serum glucose, triglyceride (tg), low-density lipoprotein (ldl), phosphorus (p), alkaline phosphatase (alp), aspartate aminotransferase (ast), and alanine transaminase (alt) in the newly hatched chickens (p < 0.05). |
2024-01-10 |
2024-01-13 |
chicken |
| Tomoya Shirakawa, Julius Fink, Zen-U Hotta, Yosuke Shimada, Yan Lu, Junhua Du, Kazuhito Matsushita, Satoshi Hori, Hisamitsu Ide, Shigeo Hori. The impact of serum testosterone level to reflect age-related multi-organ functions. Endocrine journal. 2024-01-08. PMID:38191198. |
a multiple regression analysis was conducted to determine whether biomarkers including hemoglobin (hb), hematocrit (hct), luteinizing hormone (lh), follicle stimulating hormone (fsh), alkaline phosphatase (alp), albumin (alb), creatinine (cre), aspartate aminotransferase (ast), alanine aminotransferase (alt), glucose (glu), c-reactive protein (crp), triglycerides (tg), high-density lipoprotein cholesterol (hdl-c), and low-density lipoprotein cholesterol (ldl-c) values were associated with serum total testosterone concentration. |
2024-01-08 |
2024-01-10 |
human |
| Jarawee Supanta, Janine L Brown, Pakkanut Bansiddhi, Chatchote Thitaram, Veerasak Punyapornwithaya, Khanittha Punturee, Nopphamas Somboon, Patcharapa Towiboon, Jaruwan Khonme. Physiological changes in captive elephants in Northern Thailand as a result of the COVID-19 tourism ban - muscle, liver, metabolic function, and body condition. Frontiers in veterinary science. vol 10. 2024-01-05. PMID:38179326. |
fifty-eight elephants from six tourist camps were assigned a body condition score (bcs) and blood samples were collected monthly for 2 years during the travel ban to measure: (1) muscle enzymes [creatine kinase (ck), aspartate aminotransferase (ast)]; (2) liver enzymes [aspartate aminotransferase (ast), alkaline phosphatase (alp), gamma-glutamyl transferase (ggt)]; (3) lipids [total cholesterol (tc), triglycerides (tg), low (ldl) and high (hdl) density lipoproteins]; and metabolic function [glucose, insulin, fructosamine]. |
2024-01-05 |
2024-01-07 |
Not clear |