| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Elena P Khashchenko, Mikhail Yu Vysokikh, Maria V Marey, Ksenia O Sidorova, Ludmila A Manukhova, Natalya N Shkavro, Elena V Uvarova, Vladimir D Chuprynin, Timur Kh Fatkhudinov, Leila V Adamyan, Gennady T Sukhik. Altered Glycolysis, Mitochondrial Biogenesis, Autophagy and Apoptosis in Peritoneal Endometriosis in Adolescents. International journal of molecular sciences. vol 25. issue 8. 2024-04-27. PMID:38673823. |
samples of plasma and peritoneal fluid exosomes, endometrioid foci and non-affected peritoneum were tested for estrogen receptor (erα/β), hexokinase (hex2), pyruvate dehydrogenase kinase (pdk1), glucose transporter (glut1), monocarboxylate transporters (mct1 and mct2), optic atrophy 1 (opa1, mitochondrial fusion protein), dynamin-related protein 1 (drp1, mitochondrial fission protein), bax, bcl2, beclin1, bnip3, p38 mitogen-activated protein kinase (mapk), hypoxia-inducible factor 1 (hif-1α), mitochondrial voltage-dependent anion channel (vdac) and transforming growth factor (tgfβ) proteins as markers of estrogen signaling, glycolysis rates, mitochondrial biogenesis and damage, apoptosis and autophagy (western-blot and pcr). |
2024-04-27 |
2024-04-29 |
Not clear |
| Qing-Qing Wu, Qi Yao, Tong-Tong Hu, Ying Wan, Qing-Wen Xie, Jin-Hua Zhao, Yuan Yuan, Qi-Zhu Tan. Tax1 banding protein 1 exacerbates heart failure in mice by activating ITCH-P73-BNIP3-mediated cardiomyocyte apoptosis. Acta pharmacologica Sinica. 2022-08-10. PMID:35948751. |
we demonstrated that the pro-heart failure effect of tax1bp1 resulted from its interaction with the e3 ligase itch to promote the transcription factor p73 ubiquitination and degradation, causing enhanced bcl2 interacting protein 3 (bnip3)-mediated cardiomyocyte apoptosis. |
2022-08-10 |
2023-08-14 |
mouse |
| Ngoc Tuan Tran, Yanlian Zhou, Lianjie Chen, Zaiqiao Sun, Shengkang L. SpBNIP3 regulates apoptosis and autophagy in mud crab (Scylla paramamosain) during white spot syndrome virus infection. Developmental and comparative immunology. 2022-06-11. PMID:35690229. |
bnip3 (bcl2 and adenovirus e1b 19-kda-interacting protein 3), which is a pro-apoptotic protein in the bcl-2 family involves a variety of cell signaling pathways, including mitochondrial dysfunction, mitochondrial autophagy, and apoptosis in vertebrates. |
2022-06-11 |
2023-08-14 |
Not clear |
| Yansong Li, Shuhong Ren, Jingwen Xia, Yong Wei, Yinhua X. EIF4A3-Induced circ-BNIP3 Aggravated Hypoxia-Induced Injury of H9c2 Cells by Targeting miR-27a-3p/BNIP3. Molecular therapy. Nucleic acids. vol 19. 2021-01-10. PMID:31923741. |
bcl2 interaction protein 3 (bnip3) can be upregulated by hypoxia and participates in the mediation of hypoxia-activated apoptosis in cardiac myocyte death. |
2021-01-10 |
2023-08-13 |
Not clear |
| Ryo Nishimura, Kiyoshi Okuda, Yosuke Gunji, Ahmed Magzoub Khalid, Yoshiaki Yamano, Yasuhisa Yamashita, Mitsugu Hishinum. BNIP3 expression in bovine follicle and corpus luteum. The Journal of veterinary medical science. vol 80. issue 2. 2018-09-28. PMID:29269703. |
bnip3 (bcl2/adenovirus e1b nineteen kilodalton interacting protein-3), a member of the bcl2 family, is activated under hypoxic conditions and induces apoptosis or mitochondrial autophagy for adapting cells to hypoxia. |
2018-09-28 |
2023-08-13 |
cattle |
| Rathinavel Ashokkumar, Sankar Jamuna, M S Sakeena Sadullah, S Niranjali Devara. Vitexin protects isoproterenol induced post myocardial injury by modulating hipposignaling and ER stress responses. Biochemical and biophysical research communications. vol 496. issue 2. 2018-02-16. PMID:29406244. |
iso mediated apoptosis was found to be associated with er permeabilization and characterized by enhanced production of ros, activation of caspase-3, modulation of bcl2 family proteins and activation of bnip3. |
2018-02-16 |
2023-08-13 |
Not clear |
| Ulrike B Hendgen-Cotta, Sonja Esfeld, Katharina Rudi, Ilkka Miinalainen, Johann P Klare, Tienush Rassa. Cytosolic BNIP3 Dimer Interacts with Mitochondrial BAX Forming Heterodimers in the Mitochondrial Outer Membrane under Basal Conditions. International journal of molecular sciences. vol 18. issue 4. 2017-04-28. PMID:28333095. |
we investigated the basal distribution of cardiac bnip3 in vivo and its physical interaction with the pro-death protein bcl2 associated x, apoptosis regulator (bax) and with mitochondria using immunoblot analysis, co-immunoprecipitation, and continuous wave and pulsed electron paramagnetic resonance spectroscopy techniques. |
2017-04-28 |
2023-08-13 |
Not clear |
| Decui Shao, Jun Ni, Yang Shen, Jia Liu, Li Zhou, Hong Xue, Yu Huang, Wei Zhang, Limin L. CHOP mediates XBP1S-induced renal mesangial cell necrosis following high glucose treatment. European journal of pharmacology. vol 758. 2016-04-26. PMID:25857226. |
apoptosis and necrosis were quantified by flow cytometry; protein levels of xbp1s, caspase3, bax, bcl2, bnip3, and chop were analyzed by western blotting. |
2016-04-26 |
2023-08-13 |
Not clear |
| A Lin, J Yao, L Zhuang, D Wang, J Han, E W-F Lam, B Ga. The FoxO-BNIP3 axis exerts a unique regulation of mTORC1 and cell survival under energy stress. Oncogene. vol 33. issue 24. 2014-08-07. PMID:23851496. |
integrated transcriptomic and functional analyses identified bcl2/adenovirus e1b 19 kda protein-interacting protein 3 (bnip3)-a negative regulator of both rheb and bcl2 prosurvival family members-as a key downstream target of foxos to inhibit mtorc1 function and promote apoptosis in response to energy stress. |
2014-08-07 |
2023-08-12 |
human |
| Benigno C Valdez, David Murray, Latha Ramdas, Marcos de Lima, Roy Jones, Steven Kornblau, Daniel Betancourt, Yang Li, Richard E Champlin, Borje S Andersso. Altered gene expression in busulfan-resistant human myeloid leukemia. Leukemia research. vol 32. issue 11. 2008-10-03. PMID:18339423. |
both resistant sublines evade bu-mediated g2-arrest and apoptosis with altered regulations of chk2 and cdc2 proteins, constitutively up-regulated anti-apoptotic genes (bcl-x(l), bcl2, bcl2l10, bag3 and iap2/birc3) and down-regulated pro-apoptotic genes (bik, bnip3, and ltbr). |
2008-10-03 |
2023-08-12 |
human |
| Noömi Lombaert, Dominique Lison, Paul Van Hummelen, Micheline Kirsch-Volder. In vitro expression of hard metal dust (WC-Co)--responsive genes in human peripheral blood mononucleated cells. Toxicology and applied pharmacology. vol 227. issue 2. 2008-03-31. PMID:18078969. |
quantitative rt-pcr data for a selection of the most strongly modulated genes (hmox1, hspa1a, hspa1l, bnip3, bnip3l, adora2b, mt3, pla2g7, tnfaip6), and some additionally chosen apoptosis related genes (bcl2, bax, fas, fasl, tnfalpha), confirmed the microarray data after wc-co exposure and demonstrated limited differences between the co-containing compounds. |
2008-03-31 |
2023-08-12 |
human |
| Simran Banga, Ping Gao, Xihui Shen, Valena Fiscus, Wei-Xing Zong, Lingling Chen, Zhao-Qing Lu. Legionella pneumophila inhibits macrophage apoptosis by targeting pro-death members of the Bcl2 protein family. Proceedings of the National Academy of Sciences of the United States of America. vol 104. issue 12. 2007-04-30. PMID:17360363. |
sidf contributes to apoptosis resistance in l. pneumophila-infected cells by specifically interacting with and neutralizing the effects of bnip3 and bcl-rambo, two proapoptotic members of bcl2 protein family. |
2007-04-30 |
2023-08-12 |
Not clear |
| Annemieke J M de Ruijter, Rutger J Meinsma, Peter Bosma, Stephan Kemp, Huib N Caron, André B P van Kuilenbur. Gene expression profiling in response to the histone deacetylase inhibitor BL1521 in neuroblastoma. Experimental cell research. vol 309. issue 2. 2005-11-01. PMID:16084510. |
we observed changes in the expression of vital genes belonging to the cell cycle (cyclin d1 and cdk4) and apoptosis (bnip3, bid, and bcl2) pathway in response to bl1521. |
2005-11-01 |
2023-08-12 |
Not clear |