| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Li-Chai Chen, Mei-Chou Lai, Tang-Yao Hong, I-Min Li. γ-Oryzanol from Rice Bran Antagonizes Glutamate-Induced Excitotoxicity in an In Vitro Model of Differentiated HT-22 Cells. Nutrients. vol 16. issue 8. 2024-04-27. PMID:38674927. |
calcium influx triggered by glutamate subsequently activated type ii calcium/calmodulin-dependent protein kinase (camkii) in the ht-22 cells. |
2024-04-27 |
2024-04-29 |
Not clear |
| Jiawei Yang, Ying Wang, Yuyan Xia, Yajie Ren, Zhi Wang, Xin Meng, Shuangyue Li, Xiaohui Liu, Jing Sha. PFOS Elicits Cytotoxicity in Neuron Through Astrocyte-Derived CaMKII-DLG1 Signaling In Vitro Rat Hippocampal Model. Neurochemical research. 2024-02-23. PMID:38393622. |
the application of pfos showed a decreased cell viability, synapse length and glutamate transporter 1 (glt-1) expression, but an increased camkii, dlg1 and cyclic amp response element binding protein (creb) expression in primary cultured astrocyte. |
2024-02-23 |
2024-02-25 |
rat |
| Đorđe Đorović, Vesna Lazarevic, Jovana Aranđelović, Vladimir Stevanović, Wojciech Paslawski, Xiaoqun Zhang, Milica Velimirović, Nataša Petronijević, Laslo Puškaš, Miroslav M Savić, Per Svenningsso. Maternal deprivation causes CaMKII downregulation and modulates glutamate, norepinephrine and serotonin in limbic brain areas in a rat model of single prolonged stress. Journal of affective disorders. 2024-01-10. PMID:38199412. |
maternal deprivation causes camkii downregulation and modulates glutamate, norepinephrine and serotonin in limbic brain areas in a rat model of single prolonged stress. |
2024-01-10 |
2024-01-13 |
rat |
| Đorđe Đorović, Vesna Lazarevic, Jovana Aranđelović, Vladimir Stevanović, Wojciech Paslawski, Xiaoqun Zhang, Milica Velimirović, Nataša Petronijević, Laslo Puškaš, Miroslav M Savić, Per Svenningsso. Maternal deprivation causes CaMKII downregulation and modulates glutamate, norepinephrine and serotonin in limbic brain areas in a rat model of single prolonged stress. Journal of affective disorders. 2024-01-10. PMID:38199412. |
an intricate relationship exists between various neurotransmitters (such as glutamate, norepinephrine or serotonin), calcium/calmodulin-dependent protein kinase ii (camkii), as an important regulator of glutamatergic synaptic function, and ptsd. |
2024-01-10 |
2024-01-13 |
rat |
| Sarah Perry, Yifu Han, Chengjie Qiu, Chun Chien, Pragya Goel, Samantha Nishimura, Manisha Sajnani, Andreas Schmid, Stephan J Sigrist, Dion Dickma. A glutamate receptor C-tail recruits CaMKII to suppress retrograde homeostatic signaling. Nature communications. vol 13. issue 1. 2022-12-10. PMID:36496500. |
a glutamate receptor c-tail recruits camkii to suppress retrograde homeostatic signaling. |
2022-12-10 |
2023-08-14 |
Not clear |
| Jonathan E Tullis, Olivia R Buonarati, Steven J Coultrap, Ashley M Bourke, Erika L Tiemeier, Matthew J Kennedy, Paco S Herson, K Ulrich Baye. GluN2B S1303 phosphorylation by CaMKII or DAPK1: no indication for involvement in ischemia or LTP. iScience. vol 24. issue 10. 2021-11-12. PMID:34704002. |
binding of two different cam kinases, camkii and dapk1, to the nmda-type glutamate receptor (nmdar) subunit glun2b near s1303 has been implicated in excitotoxic/ischemic neuronal cell death. |
2021-11-12 |
2023-08-13 |
Not clear |
| Hyunjoong Kim, Paul C Bresslof. Stochastic Turing Pattern Formation in a Model with Active and Passive Transport. Bulletin of mathematical biology. vol 82. issue 11. 2021-10-22. PMID:33159598. |
within the context of synaptogenesis, the diffusing molecules can be identified with the protein kinase camkii and the advecting molecules as glutamate receptors. |
2021-10-22 |
2023-08-13 |
caenorhabditis_elegans |
| Tomohisa Hosokawa, Pin-Wu Liu, Qixu Cai, Joana S Ferreira, Florian Levet, Corey Butler, Jean-Baptiste Sibarita, Daniel Choquet, Laurent Groc, Eric Hosy, Mingjie Zhang, Yasunori Hayash. CaMKII activation persistently segregates postsynaptic proteins via liquid phase separation. Nature neuroscience. vol 24. issue 6. 2021-08-18. PMID:33927400. |
we found that activated camkii, a central player of synaptic plasticity, undergoes liquid-liquid phase separation with the nmda-type glutamate receptor subunit glun2b. |
2021-08-18 |
2023-08-13 |
Not clear |
| Zachary T Fitzgerald, Jacqueline K Ros. Locally-Induced CaMKII Translocation Requires Nucleotide Binding. Frontiers in synaptic neuroscience. vol 12. 2020-09-28. PMID:32116640. |
activation of nmda-type glutamate receptors results in translocation of camkii to synapses. |
2020-09-28 |
2023-08-13 |
Not clear |
| Zachary T Fitzgerald, Jacqueline K Ros. Locally-Induced CaMKII Translocation Requires Nucleotide Binding. Frontiers in synaptic neuroscience. vol 12. 2020-09-28. PMID:32116640. |
however, there are at least two distinct mechanisms by which glutamate-dependent camkii translocation occurs: one well-studied process resulting from whole-cell glutamate stimulation and one resulting from brief, local glutamate application. |
2020-09-28 |
2023-08-13 |
Not clear |
| Zachary T Fitzgerald, Jacqueline K Ros. Locally-Induced CaMKII Translocation Requires Nucleotide Binding. Frontiers in synaptic neuroscience. vol 12. 2020-09-28. PMID:32116640. |
unlike the relatively fast camkii translocation seen following whole-cell glutamate delivery (seconds), local application results in camkii translocation that occurs gradually within 6-10 min. |
2020-09-28 |
2023-08-13 |
Not clear |
| Yasushi Yabuki, Lei Wu, Kohji Fukunag. Cognitive enhancer ST101 improves schizophrenia-like behaviors in neonatal ventral hippocampus-lesioned rats in association with improved CaMKII/PKC pathway. Journal of pharmacological sciences. vol 140. issue 3. 2020-02-13. PMID:31474557. |
improved the decline in phosphorylation levels of camkii (thr-286), pkcα (ser-657), α-amino-3-hydroxy-5-methyl-4-isoxazol- propionic acid (ampa)-type glutamate receptor subunit 1 (glua1: ser-831), and n-methyl-d-aspartate (nmda) receptor subunit 1 (glun1: ser-896) in the mpfc and hippocampal ca1 regions. |
2020-02-13 |
2023-08-13 |
rat |
| Fatin Atrooz, Hesong Liu, Camila Kochi, Samina Sali. Early Life Sleep Deprivation: Role of Oxido-Inflammatory Processes. Neuroscience. vol 406. 2019-12-24. PMID:30826520. |
pfc expression of glutamate receptor subunits, post synaptic density protein (psd-95), calcium/calmodulin-dependent protein kinase (camkii), and extracellular signal-regulated kinase (erk |
2019-12-24 |
2023-08-13 |
rat |
| Basant K Pur. Calcium Signaling and Gene Expression. Advances in experimental medicine and biology. vol 1131. 2019-10-29. PMID:31646525. |
calcium influx into the postsynaptic neuron via: n-methyl-d-aspartate (nmda) receptors activates small gtpase rac1 and other rac guanine nucleotide exchange factors, and stimulates calmodulin-dependent kinase kinase (camkk) and camki; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors that are not impermeable to calcium ions, that is, those lacking the glutamate receptor-2 subunits, leads to activation of ras guanine nucleotide-releasing factor proteins, which is coupled with activation of the mitogen-activated protein kinases/extracellular signal-regulated kinases signaling cascade; l-type voltage-gated calcium channels activates signaling pathways involving camkii, downstream responsive element antagonist modulator and distinct microdomains. |
2019-10-29 |
2023-08-13 |
Not clear |
| Luis A Natividad, Michael Q Steinman, Sarah A Laredo, Cristina Irimia, Ilham Y Polis, Robert Lintz, Matthew W Buczynski, Rémi Martin-Fardon, Marisa Roberto, Loren H Parson. Phosphorylation of calcium/calmodulin-dependent protein kinase II in the rat dorsal medial prefrontal cortex is associated with alcohol-induced cognitive inflexibility. Addiction biology. vol 23. issue 5. 2019-10-22. PMID:28940879. |
a key modulator of glutamatergic activity is the holoenzyme calcium/calmodulin-dependent protein kinase ii (camkii) that phosphorylates ionotropic glutamate receptors. |
2019-10-22 |
2023-08-13 |
rat |
| Heather A Brooks, Paul C Bresslof. Turing mechanism for homeostatic control of synaptic density during C. elegans growth. Physical review. E. vol 96. issue 1-1. 2018-10-02. PMID:29347189. |
taking the passive component to be the protein kinase camkii and the active component to be the glutamate receptor glr-1, we interpret the concentration peaks as sites of new synapses along the length of c. elegans, and thus show how the density of synaptic sites can be maintained. |
2018-10-02 |
2023-08-13 |
caenorhabditis_elegans |
| Pragya Goel, Xiling Li, Dion Dickma. Disparate Postsynaptic Induction Mechanisms Ultimately Converge to Drive the Retrograde Enhancement of Presynaptic Efficacy. Cell reports. vol 21. issue 9. 2018-07-09. PMID:29186673. |
intriguingly, pharmacological blockade of postsynaptic glutamate receptors, and not calcium influx through these receptors, is necessary and sufficient to induce rapid retrograde homeostatic signaling through camkii. |
2018-07-09 |
2023-08-13 |
drosophila_melanogaster |
| Alda Fernandes, Yu-Wen L. Focused microwave irradiation-assisted immunohistochemistry to study effects of ketamine on phospho-ERK expression in the mouse brain. Brain research. vol 1670. 2018-04-26. PMID:28501494. |
we established a focused microwave irradiation-assisted ihc assay to detect phosphorylated (phospho) proteins including phospho-erk, phospho- camp-response- element-binding protein (creb), phospho- glutamate receptor 1 (glur1) and phospho- calcium/calmodulin-dependent protein kinase ii (camkii) with greater sensitivity and reproducibility in comparison to conventional ihc methods. |
2018-04-26 |
2023-08-13 |
mouse |
| Chih-Ming Chen, Lauren L Orefice, Shu-Ling Chiu, Tara A LeGates, Samer Hattar, Richard L Huganir, Haiqing Zhao, Baoji Xu, Rejji Kuruvill. Wnt5a is essential for hippocampal dendritic maintenance and spatial learning and memory in adult mice. Proceedings of the National Academy of Sciences of the United States of America. vol 114. issue 4. 2018-04-12. PMID:28069946. |
wnt5a expression in hippocampal neurons begins postnatally, and its deletion attenuated camkii and rac1 activity, reduced glun1 glutamate receptor expression, and impaired synaptic plasticity and spatial learning and memory in 3-mo-old mice. |
2018-04-12 |
2023-08-13 |
mouse |
| Jie Luo, Xiaoxia Huang, Yali Li, Yang Li, Xueqin Xu, Yan Gao, Ruoshi Shi, Wanjun Yao, Juying Liu, Changbin K. GPR30 disrupts the balance of GABAergic and glutamatergic transmission in the spinal cord driving to the development of bone cancer pain. Oncotarget. vol 7. issue 45. 2018-03-05. PMID:27608844. |
gpr30 also facilitated excitatory transmission by promoting functional up-regulation of the calcium/calmodulin-dependent protein kinase ii α (camkii α) in glutamatergic neurons and increasing the clustering of the glutamate receptor subunit 1 (glur1) subunit to excitatory synapse.taken together, gpr30 contributed to the development of bcp by both facilitating excitatory transmission and inhibiting inhibitory transmission in the spinal cord. |
2018-03-05 |
2023-08-13 |
rat |