| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiuli Chen, Hao Wu, Peibo Li, Wei Peng, Yonggang Wang, Xiaoli Zhang, Ao Zhang, Jinliang Li, Fenzhao Meng, Weiyue Wang, Weiwei S. Unraveling the Mechanism of Xiaochaihu Granules in Alleviating Yeast-Induced Fever Based on Network Analysis and Experimental Validation. Pharmaceuticals (Basel, Switzerland). vol 17. issue 4. 2024-04-27. PMID:38675434. |
xchg also downregulated the levels of 5-hydroxytryptamine (5-ht), γ-aminobutyric acid (gaba), corticotropin releasing hormone (crh), and adrenocorticotrophin (acth). |
2024-04-27 |
2024-04-29 |
mouse |
| Miho Watanabe, Adya Saran Sinha, Yohei Shinmyo, Atsuo Fukud. Early establishment of chloride homeostasis in CRH neurons is altered by prenatal stress leading to fetal HPA axis dysregulation. Frontiers in molecular neuroscience. vol 17. 2024-04-05. PMID:38577026. |
using acute slices containing the pvn of crf-venusΔneo mice, gramicidin perforated-patch clamp-recordings of crh neurons at e15, postnatal day 0 (p0), and p7 were performed to evaluate the developmental shift of gaba action. |
2024-04-05 |
2024-04-07 |
mouse |
| Li Li, Ying Su, Siyuan Wang, Chengyu Wang, Naqi Ruan, Zhiyan Hu, Xin Cheng, Jiajia Chen, Kaiming Yuan, Peijun Li, Pei Fa. Neonatal di-(2-ethylhexyl)phthalate exposure induces permanent alterations in secretory CRH neuron characteristics in the hypothalamus paraventricular region of adult male rats. Experimental neurology. 2023-11-25. PMID:38007208. |
secretory crh neurons showed higher spontaneous firing activity but could be inhibited by gaba |
2023-11-25 |
2023-11-28 |
rat |
| Caitlin McIntyre, Xiao Feng Li, Deyana Ivanova, Jun Wang, Kevin T O'Byrn. Hypothalamic PVN CRH neurons signal through PVN GABA neurons to suppress GnRH pulse generator frequency in female mice. Endocrinology. 2023-05-29. PMID:37246581. |
hypothalamic pvn crh neurons signal through pvn gaba neurons to suppress gnrh pulse generator frequency in female mice. |
2023-05-29 |
2023-08-14 |
mouse |
| Caitlin McIntyre, Xiao Feng Li, Deyana Ivanova, Jun Wang, Kevin T O'Byrn. Hypothalamic PVN CRH neurons signal through PVN GABA neurons to suppress GnRH pulse generator frequency in female mice. Endocrinology. 2023-05-29. PMID:37246581. |
pvn crh neurons signal to local gaba neurons which may provide a possible indirect mechanism by which pvn crh neurons suppress lh pulse frequency. |
2023-05-29 |
2023-08-14 |
mouse |
| Caitlin McIntyre, Xiao Feng Li, Deyana Ivanova, Jun Wang, Kevin T O'Byrn. Hypothalamic PVN CRH neurons signal through PVN GABA neurons to suppress GnRH pulse generator frequency in female mice. Endocrinology. 2023-05-29. PMID:37246581. |
to further determine whether pvn crh neurons signal through pvn gaba neurons to suppress lh pulsatility, we combined recombinase mice with intersectional vectors to selectively target these neurons. |
2023-05-29 |
2023-08-14 |
mouse |
| Caitlin McIntyre, Xiao Feng Li, Deyana Ivanova, Jun Wang, Kevin T O'Byrn. Hypothalamic PVN CRH neurons signal through PVN GABA neurons to suppress GnRH pulse generator frequency in female mice. Endocrinology. 2023-05-29. PMID:37246581. |
crh-cre::vgat-flpo mice expressing the stimulatory opsin, chrmine in non-gabaergic crh neurons alone or in combination with the inhibitory opsin nphr3.3 in non-crh expressing gaba neurons in the pvn were used. |
2023-05-29 |
2023-08-14 |
mouse |
| Caitlin McIntyre, Xiao Feng Li, Deyana Ivanova, Jun Wang, Kevin T O'Byrn. Hypothalamic PVN CRH neurons signal through PVN GABA neurons to suppress GnRH pulse generator frequency in female mice. Endocrinology. 2023-05-29. PMID:37246581. |
optogenetic stimulation of non-gabaergic crh neurons suppressed pulsatile lh secretion, however lh pulse frequency was not affected when crh neurons were stimulated and pvn gaba neurons were simultaneously inhibited. |
2023-05-29 |
2023-08-14 |
mouse |
| Matthew T Birnie, Annabel K Short, Gregory B de Carvalho, Lara Taniguchi, Benjamin G Gunn, Aidan L Pham, Christy A Itoga, Xiangmin Xu, Lulu Y Chen, Stephen V Mahler, Yuncai Chen, Tallie Z Bara. Stress-induced plasticity of a CRH/GABA projection disrupts reward behaviors in mice. Nature communications. vol 14. issue 1. 2023-02-25. PMID:36841826. |
we characterize a stress-sensitive projection connecting basolateral amygdala (bla) and nucleus accumbens (nac) that co-expresses gaba and the stress-reactive neuropeptide corticotropin-releasing hormone (crh). |
2023-02-25 |
2023-08-14 |
mouse |
| Ruksana Yesmin, Miho Watanabe, Adya Saran Sinha, Masaru Ishibashi, Tianying Wang, Atsuo Fukud. A subpopulation of agouti-related peptide neurons exciting corticotropin-releasing hormone axon terminals in median eminence led to hypothalamic-pituitary-adrenal axis activation in response to food restriction. Frontiers in molecular neuroscience. vol 15. 2022-10-17. PMID:36245920. |
the excitatory action of gamma-aminobutyric-acid (gaba) in the median-eminence (me) led to the steady-state release of corticotropin-releasing hormone (crh) from crh axon terminals, which modulates the hypothalamic-pituitary-adrenal (hpa) axis. |
2022-10-17 |
2023-08-14 |
mouse |
| Ryuji Sakakibara, Shuichi Katsuragaw. Voiding and storage symptoms in depression/anxiety. Autonomic neuroscience : basic & clinical. vol 237. 2021-12-19. PMID:34923228. |
these findings might reflect the biological changes of the depressive brain; e.g., decreases in serotonin and gaba, and possible increases in crh. |
2021-12-19 |
2023-08-13 |
Not clear |
| Stephen C Gammi. Creation of a gene expression portrait of depression and its application for identifying potential treatments. Scientific reports. vol 11. issue 1. 2021-11-15. PMID:33589676. |
expression patterns suggested decreased signaling for gaba and for neuropeptides, crh, sst, and cck. |
2021-11-15 |
2023-08-13 |
Not clear |
| Robert Lund. Comparison of GABA, Somatostatin, and Corticotrophin-Releasing Hormone Expression in Axon Terminals That Target the Parabrachial Nucleus. Chemical senses. vol 45. issue 4. 2021-05-25. PMID:32107535. |
the majority of sst-positive axon terminals were positive for gaba expression, while the majority of crh terminals were not. |
2021-05-25 |
2023-08-13 |
mouse |
| Chayarndorn Phumsatitpong, Rose M De Guzman, Damian G Zuloaga, Suzanne M Moente. A CRH Receptor Type 1 Agonist Increases GABA Transmission to GnRH Neurons in a Circulating-Estradiol-Dependent Manner. Endocrinology. vol 161. issue 11. 2021-01-29. PMID:32798220. |
a crh receptor type 1 agonist increases gaba transmission to gnrh neurons in a circulating-estradiol-dependent manner. |
2021-01-29 |
2023-08-13 |
mouse |
| Louis Monti, Michael R Liebowit. Neural circuits of anxiolytic and antidepressant CNS spectrums. 2020-12-11. PMID:33092667. |
we hypothesize that afferent signals triggered by activation of these peripheral receptors could reach subgroups of olfactory bulb neurons broadcasting information to gamma-aminobutyric acid (gabaergic) and corticotropin-releasing hormone (crh) neurons in the limbic amygdala. |
2020-12-11 |
2023-08-13 |
human |
| Andrew Hooper, Patrick M Fuller, Jamie Maguir. Hippocampal corticotropin-releasing hormone neurons support recognition memory and modulate hippocampal excitability. PloS one. vol 13. issue 1. 2018-03-09. PMID:29346425. |
additional experiments are needed to reconcile the functions of gaba and crh signaling of hippocampal crh neurons on hippocampal function. |
2018-03-09 |
2023-08-13 |
mouse |
| Keisuke Kakizawa, Miho Watanabe, Hiroki Mutoh, Yuta Okawa, Miho Yamashita, Yuchio Yanagawa, Keiichi Itoi, Takafumi Suda, Yutaka Oki, Atsuo Fukud. A novel GABA-mediated corticotropin-releasing hormone secretory mechanism in the median eminence. Science advances. vol 2. issue 8. 2017-07-26. PMID:27540587. |
the excitability of crh neurons is regulated by γ-aminobutyric acid (gaba)-containing neurons projecting to the pvn. |
2017-07-26 |
2023-08-13 |
mouse |
| Keisuke Kakizawa, Miho Watanabe, Hiroki Mutoh, Yuta Okawa, Miho Yamashita, Yuchio Yanagawa, Keiichi Itoi, Takafumi Suda, Yutaka Oki, Atsuo Fukud. A novel GABA-mediated corticotropin-releasing hormone secretory mechanism in the median eminence. Science advances. vol 2. issue 8. 2017-07-26. PMID:27540587. |
we investigated the role of gaba in the regulation of crh release. |
2017-07-26 |
2023-08-13 |
mouse |
| Keisuke Kakizawa, Miho Watanabe, Hiroki Mutoh, Yuta Okawa, Miho Yamashita, Yuchio Yanagawa, Keiichi Itoi, Takafumi Suda, Yutaka Oki, Atsuo Fukud. A novel GABA-mediated corticotropin-releasing hormone secretory mechanism in the median eminence. Science advances. vol 2. issue 8. 2017-07-26. PMID:27540587. |
the release of crh was impaired, accumulating in the cell bodies of crh neurons in heterozygous gad67-gfp (green fluorescent protein) knock-in mice (gad67(+/gfp)), which exhibited decreased gaba content. |
2017-07-26 |
2023-08-13 |
mouse |
| Keisuke Kakizawa, Miho Watanabe, Hiroki Mutoh, Yuta Okawa, Miho Yamashita, Yuchio Yanagawa, Keiichi Itoi, Takafumi Suda, Yutaka Oki, Atsuo Fukud. A novel GABA-mediated corticotropin-releasing hormone secretory mechanism in the median eminence. Science advances. vol 2. issue 8. 2017-07-26. PMID:27540587. |
we propose a novel mechanism by which the excitatory action of gaba maintains a steady-state crh release from axon terminals in the me. |
2017-07-26 |
2023-08-13 |
mouse |