| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiuli Chen, Hao Wu, Peibo Li, Wei Peng, Yonggang Wang, Xiaoli Zhang, Ao Zhang, Jinliang Li, Fenzhao Meng, Weiyue Wang, Weiwei S. Unraveling the Mechanism of Xiaochaihu Granules in Alleviating Yeast-Induced Fever Based on Network Analysis and Experimental Validation. Pharmaceuticals (Basel, Switzerland). vol 17. issue 4. 2024-04-27. PMID:38675434. |
xchg also downregulated the levels of 5-hydroxytryptamine (5-ht), γ-aminobutyric acid (gaba), corticotropin releasing hormone (crh), and adrenocorticotrophin (acth). |
2024-04-27 |
2024-04-29 |
mouse |
| Viridiana Alcántara-Alonso, Cinthia García-Luna, Paulina Soberanes-Chávez, Erika Estrada-Camarena, Patricia de Gortar. Two Adverse Early Life Events Induce Differential Changes in Brain CRH and Serotonin Systems in Rats along with Hyperphagia and Depression. Journal of integrative neuroscience. vol 23. issue 2. 2024-02-29. PMID:38419452. |
two adverse early life events induce differential changes in brain crh and serotonin systems in rats along with hyperphagia and depression. |
2024-02-29 |
2024-03-02 |
rat |
| Verónica Trujillo, Tays Araújo Camilo, Evandro Valentim-Lima, Quézia S R Carbalan, Raoni C Dos-Santos, Viviane Felintro, Luís C Reis, Danilo Lustrino, Rodrigo Rorato, André S Mecaw. Neonatal treatment with para-chlorophenylalanine (pCPA) induces adolescent hyperactivity associated with changes in the paraventricular nucleus Crh and Trh expressions. Behavioural brain research. 2024-01-21. PMID:38246394. |
our results indicate that neonatal pcpa-treatment results in a long-lasting and sex-dependent drn 5-ht synthesis changes, decreased crh, and increased trh expression in the pvn, resulting in a hyperactivity-like phenotype during adolescence. |
2024-01-21 |
2024-01-24 |
rat |
| Jiao Ma, Chen-Yang Guo, Han-Bing Li, Su-Hui Wu, Gen-Lin L. Prophylactic Effects of Hemp Seed Oil on Perimenopausal Depression: A Role of HPA Axis. Journal of oleo science. 2023-09-13. PMID:37704445. |
sucrose preference test (spt), forced swimming test (fst), open field test (oft), estrogen receptor α (erα) and estrogen receptor β (erβ) expression, estradiol (e2), follicle stimulating hormone (fsh), luteinizing hormone (lh), cortisol (cort), adrenocorticotropic hormone (acth), corticotropin releasing hormone (crh), norepinephrine (ne), 5-hydroxytryptamine (5-ht) and 5-hydroxyindoleacetic acid (5hiaa) levels are measured to evaluate the function of the hypothalamic-pituitary-ovarian (hpo) and hypothalamic-pituitary-adrenal (hpa) axis. |
2023-09-13 |
2023-10-07 |
rat |
| Jiao Ma, Chen-Yang Guo, Han-Bing Li, Su-Hui Wu, Gen-Lin L. Prophylactic Effects of Hemp Seed Oil on Perimenopausal Depression: A Role of HPA Axis. Journal of oleo science. 2023-09-13. PMID:37704445. |
hso treatment significantly improves depression-like behaviors, upregulates the expression of erα and erβ, improves hpo axis function by increasing e2 levels and decreasing fsh and lh levels, reverses hpa axis hyperactivation by decreasing cort, acth, and crh levels, and upregulates ne, 5-ht, and 5hiaa levels in model rats. |
2023-09-13 |
2023-10-07 |
rat |
| Yajie Hu, Yang Liu, Shize L. Effect of Acute Cold Stress on Neuroethology in Mice and Establishment of Its Model. Animals : an open access journal from MDPI. vol 12. issue 19. 2022-10-14. PMID:36230412. |
subsequently, blood samples were collected and used for the determination of corticosterone (cort), corticotropin-releasing hormone (crh), epinephrine (e), norepinephrine (ne), dopamine (da) and 5-hydroxytryptamine (5-ht) by enzyme-linked immunosorbent assay (elisa). |
2022-10-14 |
2023-08-14 |
mouse |
| Yajie Hu, Yang Liu, Shize L. Effect of Acute Cold Stress on Neuroethology in Mice and Establishment of Its Model. Animals : an open access journal from MDPI. vol 12. issue 19. 2022-10-14. PMID:36230412. |
the physiological basis of these behavioral and emotional changes in mice under different intensity cold stimulation is the fluctuation of cort, crh, e, ne, da and 5-ht. |
2022-10-14 |
2023-08-14 |
mouse |
| Qiufen Li, Hua Zhou, Jingxin Ouyang, Shuaipeng Guo, Jun Zheng, Guanhong L. Effects of dietary tryptophan supplementation on body temperature, hormone, and cytokine levels in broilers exposed to acute heat stress. Tropical animal health and production. vol 54. issue 3. 2022-04-18. PMID:35435494. |
in addition, dietary supplemented with 0.18% trp reduced the levels of serum da, adr, noradrenaline (na), crh, tdo, ido, kynurenic acid, il-1β, and hypothalamic 5-hiaa/5-ht (p < 0.05), increased the levels of serum trp, 5-ht, and il-22, and upregulated the concentrations of hypothalamic trp and 5-ht in heat-stressed broilers (p < 0.05). |
2022-04-18 |
2023-08-13 |
Not clear |
| Qiufen Li, Hua Zhou, Jingxin Ouyang, Shuaipeng Guo, Jun Zheng, Guanhong L. Effects of dietary tryptophan supplementation on body temperature, hormone, and cytokine levels in broilers exposed to acute heat stress. Tropical animal health and production. vol 54. issue 3. 2022-04-18. PMID:35435494. |
moreover, dietary 0.27% trp supplementation decreased the levels of serum da, crh, tdo, and hypothalamic 5-hiaa/5-ht (p < 0.05), and upregulated the levels of serum trp, 5-ht, il-22, hypothalamic trp and 5-ht in heat-stressed broilers (p < 0.05). |
2022-04-18 |
2023-08-13 |
Not clear |
| Jing-Qi Fan, Zi-Qiao Xu, Yuan-Yuan Chen, Wei-Jing Lu, Xiao-Yan Xie, Yu-Ting Wang, Li-Xing Zhuan. Efficacy of Acupuncture for Parkinson's Disease Anxiety: Two-Stage Protocol for a Randomized Controlled Clinical Trial. Evidence-based complementary and alternative medicine : eCAM. vol 2022. 2022-02-21. PMID:35186098. |
the levels of adrenocorticotropic hormone (acth), cortisol (cort), serotonin (5-ht), and corticotropin-releasing factor (crh) in the patients' serum and the scores on the hoehn-yahr rating scale and the unified parkinson's disease rating scale (updrs) will all be considered among the secondary outcomes. |
2022-02-21 |
2023-08-13 |
human |
| Ryuji Sakakibara, Shuichi Katsuragaw. Voiding and storage symptoms in depression/anxiety. Autonomic neuroscience : basic & clinical. vol 237. 2021-12-19. PMID:34923228. |
these findings might reflect the biological changes of the depressive brain; e.g., decreases in serotonin and gaba, and possible increases in crh. |
2021-12-19 |
2023-08-13 |
Not clear |
| Eva Hucklenbruch-Rother, Christina Vohlen, Nava Mehdiani, Titus Keller, Bernhard Roth, Angela Kribs, Katrin Mehle. Delivery room skin-to-skin contact in preterm infants affects long-term expression of stress response genes. Psychoneuroendocrinology. vol 122. 2021-08-30. PMID:33027708. |
relative mrna expression of the corticotropin releasing hormone receptor 2 (crh r2), the glucocorticoid receptor gene (nr3c1), and the serotonin transporter gene (slc6a4) was significantly reduced in the delivery room ssc infants. |
2021-08-30 |
2023-08-13 |
Not clear |
| Hang Xu, Xiang Yang Zhang, Wei Wen Wang, Jiesi Wan. Hydroxychloroquine Increased Anxiety-Like Behaviors and Disrupted the Expression of Some Related Genes in the Mouse Brain. Frontiers in pharmacology. vol 12. 2021-05-08. PMID:33953673. |
furthermore, hcq decreased the mrna expression of interleukin-1beta, corticotropin-releasing hormone (crh), a serotonin transporter (slc6a4), and a microglia maker (aif1) in the hippocampus and decreased the mrna expression of brain-derived neurotrophic factor (bdnf) in both the hippocampus and amygdala. |
2021-05-08 |
2023-08-13 |
mouse |
| Shiyue Cao, Li We. Predictive value of serum CRH/5-HT ratio for postpartum depression. International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics. vol 151. issue 3. 2021-03-10. PMID:32812654. |
to analyze the changes in the serum levels of crh and 5-ht in women with postpartum depression (ppd) and to study the value of the crh/5-ht ratio for the prediction of ppd. |
2021-03-10 |
2023-08-13 |
Not clear |
| John A Maguire, Juan M Bilbao, Kaiman Kovacs, Lothar Resc. Hypothalamic neurocytoma with vasopressin immunoreactivity: Immunohistochemical and ultrastructural observations. Endocrine pathology. vol 3. issue 2. 2021-01-10. PMID:32138406. |
the neoplastic cells were immunoreactive for neuron-specific enolase (nse), synaptophysin, and vasopressin, and nonimmunoreactive for glial fibrillary acidic protein (gfap), vasoactive intestinal peptide (vip), bombesin, chromogranin, neurofilament, cytokeratins (high and low molecular weight), vimentin, s100 protein, somatostatin, β-endorphin, galactosamine, growth hormone-releasing hormone (grh), neurophysin, serotonin, adrenaline and noradrenaline, and corticotropin-releasing hormone (crh). |
2021-01-10 |
2023-08-13 |
Not clear |
| Nina C Donner, Sofia M Davies, Stephanie D Fitz, Drake M Kienzle, Anantha Shekhar, Christopher A Lowr. Crh receptor priming in the bed nucleus of the stria terminalis (BNST) induces tph2 gene expression in the dorsomedial dorsal raphe nucleus and chronic anxiety. Progress in neuro-psychopharmacology & biological psychiatry. vol 96. 2021-01-04. PMID:31415826. |
since the bnst projects heavily to the dorsal raphe nucleus (dr), the main source of brain serotonin, we here tested the hypothesis that such repeated, anxiety-inducing activation of crh receptors in the bnst alters the expression of serotonergic genes in the dr, including tph2, the gene encoding the rate-limiting enzyme for brain serotonin synthesis, and slc6a4, the gene encoding the serotonin transporter (sert). |
2021-01-04 |
2023-08-13 |
rat |
| Louis Monti, Michael R Liebowit. Neural circuits of anxiolytic and antidepressant CNS spectrums. 2020-12-11. PMID:33092667. |
alternatively, antidepressant pherines could facilitate the crh and gabaergic neurons that inhibit the release of nps from the lc, increase glutamate release from the bnst, and increase norepinephrine (ne), dopamine (da), and serotonin release from the lc, vta, and raphe nucleus, respectively. |
2020-12-11 |
2023-08-13 |
human |
| L Cai, W T Li, L L Zhang, X Q Lu, M Chen, Y Li. Long noncoding RNA GAS5 enhanced by curcumin relieves poststroke depression by targeting miR-10b/BDNF in rats. Journal of biological regulators and homeostatic agents. vol 34. issue 3. 2020-11-03. PMID:32627518. |
in the present study, the therapeutic effect of curcumin on rats with psd was detected by open field tests and tail suspension tests, as well as the examination of corticosterone and corticotropin-releasing hormone (crh) levels in the serum and neurotransmitter 5-hydroxytryptamine (5-ht), 5-hydroxyindoleacetic acid (5-hiaa) and dopamine (da) levels in the hippocampus. |
2020-11-03 |
2023-08-13 |
rat |
| Na Yue, Xue Zhou, Wen-Ting Fei, Ai-Min Li, Zi-Chen Wang, Chun Wang, Jian-Jun Zhan. [Effect of Lepidium meyenii (Maca) on neurotransmitter level and neuro-endocrine-immune network of deficiency-cold and deficiency-heat syndrome rats]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 45. issue 5. 2020-07-22. PMID:32237439. |
the levels of camp, cgmp, ne, da, 5-ht, crh, acth, cort and igm, igg, c3, c4 were detected by radio immunoassay. |
2020-07-22 |
2023-08-13 |
rat |
| Zhuo-Wei Gao, Rong-Le Ju, Min Luo, Shu-Lian Wu, Wen-Tong Zhan. The anxiolytic-like effects of ginsenoside Rg2 on an animal model of PTSD. Psychiatry research. vol 279. 2020-03-31. PMID:31103345. |
in addition, grg2 (10 and 20 mg/kg) could block the decreased levels of progesterone, allopregnanolone, serotonin (5-ht), 5-hydroxyindoleacetic acid (5-hiaa), corticotropin releasing hormone (crh), corticosterone (cort) and adrenocorticotropic hormone (acth) in the brain or serum. |
2020-03-31 |
2023-08-13 |
rat |