| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Soumia Majait, Emma C E Meessen, Mark Davids, Youssef Chahid, Steven W Olde Damink, Frank G Schaap, Ellis Marleen Kemper, Max Nieuwdorp, Maarten R Soeter. Age-Dependent Differences in Postprandial Bile-Acid Metabolism and the Role of the Gut Microbiome. Microorganisms. vol 12. issue 4. 2024-04-27. PMID:38674708. |
postprandial bile-acid levels, insulin, glucose, glp-1, c4, fgf19 and lipids were measured. |
2024-04-27 |
2024-04-29 |
Not clear |
| Ting Zeng, Xi Tang, Xiaosu Bai, Haiyan Xion. FGF19 Promotes the Proliferation and Insulin Secretion from Human Pancreatic β Cells Via the IRS1/GLUT4 Pathway. Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association. vol 132. issue 3. 2024-03-21. PMID:38513652. |
fgf19 promotes the proliferation and insulin secretion from human pancreatic β cells via the irs1/glut4 pathway. |
2024-03-21 |
2024-03-24 |
human |
| José Ursic-Bedoya, Guillaume Desandré, Carine Chavey, Pauline Marie, Arnaud Polizzi, Benjamin Rivière, Hervé Guillou, Eric Assenat, Urszula Hibner, Damien Gregoir. FGF19 and its analog Aldafermin cooperate with MYC to induce aggressive hepatocarcinogenesis. EMBO molecular medicine. 2024-01-16. PMID:38228803. |
fgf19 hormone has pleiotropic metabolic functions, including the modulation of insulin sensitivity, glucose/lipid metabolism and energy homeostasis. |
2024-01-16 |
2024-01-19 |
mouse |
| Agata Sadowska, Elżbieta Poniedziałek-Czajkowska, Radzisław Mierzyńsk. The Role of the FGF19 Family in the Pathogenesis of Gestational Diabetes: A Narrative Review. International journal of molecular sciences. vol 24. issue 24. 2023-12-23. PMID:38139126. |
fgf19 and fgf21 are thought to be associated with insulin resistance, an essential element in the pathogenesis of gdm. |
2023-12-23 |
2023-12-25 |
Not clear |
| Soumia Majait, Emma C E Meessen, Frederic Maxime Vaz, E Marleen Kemper, Samuel van Nierop, Steven W Olde Damink, Frank G Schaap, Johannes A Romijn, Max Nieuwdorp, Aad Verrips, Filip Krag Knop, Maarten R Soeter. Characterization of Postprandial Bile Acid Profiles and Glucose Metabolism in Cerebrotendinous Xanthomatosis. Nutrients. vol 15. issue 21. 2023-11-14. PMID:37960277. |
in this paper, we examined postprandial bile acid, glucose, insulin, glp-1 and fibroblast growth factor 19 (fgf19) plasma profiles in patients with ctx and matched healthy controls. |
2023-11-14 |
2023-11-20 |
human |
| Soumia Majait, Emma C E Meessen, Frederic Maxime Vaz, E Marleen Kemper, Samuel van Nierop, Steven W Olde Damink, Frank G Schaap, Johannes A Romijn, Max Nieuwdorp, Aad Verrips, Filip Krag Knop, Maarten R Soeter. Characterization of Postprandial Bile Acid Profiles and Glucose Metabolism in Cerebrotendinous Xanthomatosis. Nutrients. vol 15. issue 21. 2023-11-14. PMID:37960277. |
this novel characterization of ctx patients reveals very low circulating bile acid levels and fgf19 levels, aberrant postprandial glucose and insulin profiles, and elevated postprandial glp-1 responses. |
2023-11-14 |
2023-11-20 |
human |
| Leigang Jin, Ranyao Yang, Leiluo Geng, Aimin X. Fibroblast Growth Factor-Based Pharmacotherapies for the Treatment of Obesity-Related Metabolic Complications. Annual review of pharmacology and toxicology. 2022-09-13. PMID:36100222. |
among them, two classical members (fgf1 and fgf4) and two endocrine members (fgf19 and fgf21) are important regulators of whole-body energy homeostasis, glucose/lipid metabolism, and insulin sensitivity. |
2022-09-13 |
2023-08-14 |
Not clear |
| Meng-Nan Yang, Rong Huang, Xin Liu, Ya-Jie Xu, Wen-Juan Wang, Hua He, Guang-Hui Zhang, Tao Zheng, Fang Fang, Jian-Gao Fan, Fei Li, Jun Zhang, Jiong Li, Fengxiu Ouyang, Zhong-Cheng Lu. Fibroblast Growth Factor 19 in Gestational Diabetes Mellitus and Fetal Growth. Frontiers in endocrinology. vol 12. 2022-02-11. PMID:35145481. |
cord plasma fgf19, insulin, c-peptide, proinsulin, igf-i and igf-ii concentrations were measured. |
2022-02-11 |
2023-08-13 |
Not clear |
| Malgorzata Marchelek-Mysliwiec, Violetta Dziedziejko, Katarzyna Dolegowka, Andrzej Pawlik, Krzysztof Safranow, Joanna Stepniewska, Magda Wisniewska, Jolanta Malyszko, Kazimierz Ciechanowsk. Association of FGF19, FGF21 and FGF23 with carbohydrate metabolism parameters and insulin resistance in patients with chronic kidney disease. Journal of applied biomedicine. vol 18. issue 2-3. 2021-12-15. PMID:34907727. |
association of fgf19, fgf21 and fgf23 with carbohydrate metabolism parameters and insulin resistance in patients with chronic kidney disease. |
2021-12-15 |
2023-08-13 |
human |
| Malgorzata Marchelek-Mysliwiec, Violetta Dziedziejko, Katarzyna Dolegowka, Andrzej Pawlik, Krzysztof Safranow, Joanna Stepniewska, Magda Wisniewska, Jolanta Malyszko, Kazimierz Ciechanowsk. Association of FGF19, FGF21 and FGF23 with carbohydrate metabolism parameters and insulin resistance in patients with chronic kidney disease. Journal of applied biomedicine. vol 18. issue 2-3. 2021-12-15. PMID:34907727. |
in this study, we examined the association of fgf19, fgf21 and fgf23 with selected parameters related to carbohydrate metabolism and insulin resistance in non diabetic patients with predialysis ckd and in non diabetic patients after renal transplantation. |
2021-12-15 |
2023-08-13 |
human |
| Shanshan Zhao, Dongyu Wang, Zhuyu Li, Shuqia Xu, Haitian Chen, Wenjing Ding, Juan Yang, Weihua Zhao, Bo Sun, Zilian Wan. FGF15/FGF19 alleviates insulin resistance and upregulates placental IRS1/GLUT expression in pregnant mice fed a high-fat diet. Placenta. vol 112. 2021-11-10. PMID:34329971. |
this study aimed to evaluate whether fgf19 can alleviate insulin resistance and change the expression of placental irs1/gluts. |
2021-11-10 |
2023-08-13 |
mouse |
| Ai Guo, Kai Li, Hong-Chuan Tian, Zhen Fan, Qiu-Nan Chen, Yun-Fei Yang, Jing Yu, Yong-Xin Wu, Qian Xia. FGF19 protects skeletal muscle against obesity-induced muscle atrophy, metabolic derangement and abnormal irisin levels via the AMPK/SIRT-1/PGC-α pathway. Journal of cellular and molecular medicine. vol 25. issue 7. 2021-09-21. PMID:33751819. |
fgf19 treatment restored pa- and hfd-induced hyperglycaemia, impaired glucose tolerance and insulin resistance (irs-1, glut-4) and mitigated the pa- and hfd-induced decrease in fndc-5/irisin expression. |
2021-09-21 |
2023-08-13 |
mouse |
| M Qin, H P Wang, B Song, Y L Sun, D Y Wang, M Chen, H X Shi, H Zhang, Z J L. [Relationship between insulin resistance, serum VCAM-1, FGF19, IGF-1 and colorectal polyps]. Zhonghua zhong liu za zhi [Chinese journal of oncology]. vol 43. issue 5. 2021-05-27. PMID:34034475. |
[relationship between insulin resistance, serum vcam-1, fgf19, igf-1 and colorectal polyps]. |
2021-05-27 |
2023-08-13 |
Not clear |
| Manjunath Ramanjaneya, Milin Bensila, Ilham Bettahi, Jayakumar Jerobin, Tareq A Samra, Myint Myint Aye, Meis Alkasem, Kodappully Sivaraman Siveen, Thozhukat Sathyapalan, Monica Skarulis, Stephen Lawrence Atkin, Abdul-Badi Abou-Samr. Dynamic Changes in Circulating Endocrine FGF19 Subfamily and Fetuin-A in Response to Intralipid and Insulin Infusions in Healthy and PCOS Women. Frontiers in endocrinology. vol 11. 2021-05-21. PMID:33101202. |
dynamic changes in circulating endocrine fgf19 subfamily and fetuin-a in response to intralipid and insulin infusions in healthy and pcos women. |
2021-05-21 |
2023-08-13 |
Not clear |
| Anna Socha-Banasiak, Arkadiusz Michalak, Krzysztof Pacześ, Zuzanna Gaj, Wojciech Fendler, Anna Socha, Ewa Głowacka, Karolina Kapka, Violetta Gołąbek, Elżbieta Czkwianian. Klotho and fibroblast growth factors 19 and 21 serum concentrations in children and adolescents with normal body weight and obesity and their associations with metabolic parameters. BMC pediatrics. vol 20. issue 1. 2021-05-14. PMID:32546231. |
we analyzed the role of fgf19, fgf21 and klotho protein in children with normal body weight as well as in overweight and obese subjects and explored their associations with insulin resistance (ir) and metabolic syndrome (ms) and its components. |
2021-05-14 |
2023-08-13 |
human |
| Jianlou Niu, Jing Zhao, Jiamin Wu, Guanting Qiao, Junlian Gu, Chuanren Zhou, Qi Li, Lei Ying, Dezhong Wang, Huan Lin, Xiaokun Li, Moosa Mohammadi, Zhifeng Huan. Curtailing FGF19's mitogenicity by suppressing its receptor dimerization ability. Proceedings of the National Academy of Sciences of the United States of America. vol 117. issue 46. 2021-01-25. PMID:33144503. |
as a physiological regulator of bile acid homeostasis, fgf19 is also a potent insulin sensitizer capable of normalizing plasma glucose concentration, improving lipid profile, ameliorating fatty liver disease, and causing weight loss in both diabetic and diet-induced obesity mice. |
2021-01-25 |
2023-08-13 |
mouse |
| Michael J Weaver, Scott A McHenry, Gregory S Sayuk, C Prakash Gyawali, Nicholas O Davidso. Bile Acid Diarrhea and NAFLD: Shared Pathways for Distinct Phenotypes. Hepatology communications. vol 4. issue 4. 2020-09-28. PMID:32258945. |
in addition, fgf19 modulates hepatic metabolic homeostatic response signaling by means of the fibroblast growth factor receptor 4/klotho beta receptor to activate cascades involved in hepatic lipogenesis, fatty acid oxidation, and insulin sensitivity. |
2020-09-28 |
2023-08-13 |
Not clear |
| Meng Zhao, Yunshin Jung, Zewen Jiang, Katrin J Svensso. Regulation of Energy Metabolism by Receptor Tyrosine Kinase Ligands. Frontiers in physiology. vol 11. 2020-09-28. PMID:32372975. |
our current understanding of the molecular, biochemical and genetic control of energy homeostasis by the endocrine rtk ligands insulin, fgf21 and fgf19 are now relatively well understood. |
2020-09-28 |
2023-08-13 |
Not clear |
| Gabriella V Hernandez, Victoria A Smith, Megan Melnyk, Matthew A Burd, Kimberly A Sprayberry, Mark S Edwards, Daniel G Peterson, Darin C Bennet, Rob K Fanter, Daniel A Columbus, Juan P Steibel, Hunter Glanz, Chad Immoos, Margaret S Rice, Tasha M Santiago-Rodriguez, Jason Blank, Jennifer J VanderKelen, Christopher L Kitts, Brian D Piccolo, Michael R La Frano, Douglas G Burrin, Magdalena Maj, Rodrigo Manjari. Dysregulated FXR-FGF19 signaling and choline metabolism are associated with gut dysbiosis and hyperplasia in a novel pig model of pediatric NASH. American journal of physiology. Gastrointestinal and liver physiology. vol 318. issue 3. 2020-08-03. PMID:32003601. |
hff-fed pigs developed nash, cholestasis, and impaired enterohepatic farnesoid-x receptor (fxr)-fibroblast growth factor 19 (fgf19) signaling in the absence of obesity and insulin resistance. |
2020-08-03 |
2023-08-13 |
Not clear |
| Patrick J Antonellis, Brian A Droz, Richard Cosgrove, Libbey S O'Farrell, Tamer Coskun, James W Perfield, Steven Bauer, Mark Wade, Tara E Chouinard, Joseph T Brozinick, Andrew C Adams, Ricardo J Samm. The anti-obesity effect of FGF19 does not require UCP1-dependent thermogenesis. Molecular metabolism. vol 30. 2020-06-23. PMID:31767164. |
administration of fgf19 to obese/diabetic mice lowers body weight, improves insulin sensitivity, and enhances glycemic control. |
2020-06-23 |
2023-08-13 |
mouse |