| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Laris Achlaug, Irina Langier Goncalves, Ami Aronhei. Cardioprotection and Suppression of Fibrosis by Diverse Cancer and Non-Cancer Cell Lines in a Murine Model of Duchenne Muscular Dystrophy. International journal of molecular sciences. vol 25. issue 8. 2024-04-27. PMID:38673859. |
the injection of integrin β1 ko pymt cancer cells and mouse embryo fibroblasts cells (mef) resulted in the improvement of cardiac function and decreased fibrosis in the heart, diaphragm, and skeletal muscles of mdx mice. |
2024-04-27 |
2024-04-29 |
mouse |
| Han Zhou, Xuefei Tian, Alda Tufro, Gilbert Moeckel, Shuta Ishibe, Julie Goodwi. Loss of the podocyte glucocorticoid receptor exacerbates proteinuria after injury. Scientific reports. vol 7. issue 1. 2019-04-23. PMID:28852159. |
expression of several key slit diaphragm protein was down regulated in pgr ko mice. |
2019-04-23 |
2023-08-13 |
mouse |
| Fabian Dorninger, Ruth Herbst, Bojana Kravic, Bahar Z Camurdanoglu, Igor Macinkovic, Gerhard Zeitler, Sonja Forss-Petter, Siegfried Strack, Muzamil Majid Khan, Hans R Waterham, Rüdiger Rudolf, Said Hashemolhosseini, Johannes Berge. Reduced muscle strength in ether lipid-deficient mice is accompanied by altered development and function of the neuromuscular junction. Journal of neurochemistry. vol 143. issue 5. 2017-12-07. PMID:28555889. |
structurally, a morphologic examination of the neuromuscular junction (nmj) in diaphragm muscle at different developmental stages revealed aberrant axonal branching and a strongly increased area of nerve innervation in gnpat ko mice. |
2017-12-07 |
2023-08-13 |
mouse |
| Fabian Dorninger, Ruth Herbst, Bojana Kravic, Bahar Z Camurdanoglu, Igor Macinkovic, Gerhard Zeitler, Sonja Forss-Petter, Siegfried Strack, Muzamil Majid Khan, Hans R Waterham, Rüdiger Rudolf, Said Hashemolhosseini, Johannes Berge. Reduced muscle strength in ether lipid-deficient mice is accompanied by altered development and function of the neuromuscular junction. Journal of neurochemistry. vol 143. issue 5. 2017-12-07. PMID:28555889. |
electrophysiological evaluation of the adult diaphragm indicated that although evoked potentials were unaltered in gnpat ko mice, ether lipid deficiency leads to fewer spontaneous synaptic vesicle fusion events but, conversely, an increased post-synaptic response to spontaneous vesicle exocytosis. |
2017-12-07 |
2023-08-13 |
mouse |
| Sakiko Matsumoto, Sumiko Kiryu-Seo, Hiroshi Kiyam. Motor Nerve Arborization Requires Proteolytic Domain of Damage-Induced Neuronal Endopeptidase (DINE) during Development. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 17. 2017-06-19. PMID:27122033. |
in line with this, dine-deficient (dine ko) embryos fail to arborize phrenic motor nerves in the diaphragm and to form proper neuromuscular junctions (nmj), which lead to death shortly after birth. |
2017-06-19 |
2023-08-13 |
mouse |
| D Randazzo, B Blaauw, C Paolini, E Pierantozzi, S Spinozzi, S Lange, J Chen, F Protasi, C Reggiani, V Sorrentin. Exercise-induced alterations and loss of sarcomeric M-line organization in the diaphragm muscle of obscurin knockout mice. American journal of physiology. Cell physiology. vol 312. issue 1. 2017-06-06. PMID:27784675. |
on the same line, electron microscopy revealed that, in the diaphragm of exercised obscurin ko mice, but not in the hindlimb muscles, both m-line and h-zone of sarcomeres appeared wavy and less defined. |
2017-06-06 |
2023-08-13 |
mouse |
| D Randazzo, B Blaauw, C Paolini, E Pierantozzi, S Spinozzi, S Lange, J Chen, F Protasi, C Reggiani, V Sorrentin. Exercise-induced alterations and loss of sarcomeric M-line organization in the diaphragm muscle of obscurin knockout mice. American journal of physiology. Cell physiology. vol 312. issue 1. 2017-06-06. PMID:27784675. |
histological analysis indicated that heavy exercise induced leukocyte infiltration, fibrotic connective tissue deposition, and hypercontractures in the diaphragm of ko mice. |
2017-06-06 |
2023-08-13 |
mouse |
| Yoshiyasu Fukusumi, Ayako Wakamatsu, Natsumi Takashima, Eriko Hasegawa, Naoko Miyauchi, Masayuki Tomita, Hiroshi Kawach. SV2B is essential for the integrity of the glomerular filtration barrier. Laboratory investigation; a journal of technical methods and pathology. vol 95. issue 5. 2015-08-03. PMID:25730372. |
it was also found that the expression of cd2ap, nephrin, and neph1, the functional molecules of the slit diaphragm, and laminin, a critical component of the gbm, is clearly altered in sv2b ko mice. |
2015-08-03 |
2023-08-13 |
mouse |
| E Giacomello, M Quarta, C Paolini, R Squecco, P Fusco, L Toniolo, B Blaauw, L Formoso, D Rossi, C Birkenmeier, L L Peters, F Francini, F Protasi, C Reggiani, V Sorrentin. Deletion of small ankyrin 1 (sAnk1) isoforms results in structural and functional alterations in aging skeletal muscle fibers. American journal of physiology. Cell physiology. vol 308. issue 2. 2015-03-17. PMID:25354526. |
moreover, reduced qγ charge and l-type ca(2+) current, which are indexes of affected excitation-contraction coupling, were observed in diaphragm fibers from 12- to 15-mo-old mice, but not in other skeletal muscles from sank1 ko mice. |
2015-03-17 |
2023-08-13 |
mouse |
| E Giacomello, M Quarta, C Paolini, R Squecco, P Fusco, L Toniolo, B Blaauw, L Formoso, D Rossi, C Birkenmeier, L L Peters, F Francini, F Protasi, C Reggiani, V Sorrentin. Deletion of small ankyrin 1 (sAnk1) isoforms results in structural and functional alterations in aging skeletal muscle fibers. American journal of physiology. Cell physiology. vol 308. issue 2. 2015-03-17. PMID:25354526. |
with increasing age (at 12-15 mo of age) extensor digitorum longus (edl) skeletal muscles of sank1 ko mice develop prematurely large tubular aggregates, whereas diaphragm undergoes significant structural damage. |
2015-03-17 |
2023-08-13 |
mouse |
| Y Lecarpentier, X Krokidis, P Martin, T Pineau, J-L Hébert, J Quillard, M Cortes-Morichetti, C Coiraul. Increased entropy production in diaphragm muscle of PPAR alpha knockout mice. Journal of theoretical biology. vol 250. issue 1. 2008-03-19. PMID:17980390. |
the behavior of both wild type (wt) and ko diaphragm was shown to be near-equilibrium and in a stationary state, but ko was farther from equilibrium than wt. |
2008-03-19 |
2023-08-12 |
mouse |
| Y Lecarpentier, X Krokidis, P Martin, T Pineau, J-L Hébert, J Quillard, M Cortes-Morichetti, C Coiraul. Increased entropy production in diaphragm muscle of PPAR alpha knockout mice. Journal of theoretical biology. vol 250. issue 1. 2008-03-19. PMID:17980390. |
in ko diaphragm, a marked increase in entropy production (a/t x upsilon) accounted for major thermodynamic dysfunction and a dramatic increase in irreversible chemical processes during the myosin cb cycle. |
2008-03-19 |
2023-08-12 |
mouse |
| Y Lecarpentier, X Krokidis, P Martin, T Pineau, J-L Hébert, J Quillard, M Cortes-Morichetti, C Coiraul. Increased entropy production in diaphragm muscle of PPAR alpha knockout mice. Journal of theoretical biology. vol 250. issue 1. 2008-03-19. PMID:17980390. |
the thermodynamic consequences of the absence of ppar alpha were investigated in diaphragm muscle of ppar alpha knockout mice (ko). |
2008-03-19 |
2023-08-12 |
mouse |
| Y Lecarpentier, X Krokidis, P Martin, T Pineau, J-L Hébert, J Quillard, M Cortes-Morichetti, C Coiraul. Increased entropy production in diaphragm muscle of PPAR alpha knockout mice. Journal of theoretical biology. vol 250. issue 1. 2008-03-19. PMID:17980390. |
in ko diaphragm, a substantial decrease in contractile function was associated with an increase in both a/t and upsilon and with profound histological injuries such as contraction band necrosis. |
2008-03-19 |
2023-08-12 |
mouse |