| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Juan Andrés García-Loredo, Michelle G Santoyo-Suarez, Oscar Rodríguez-Nuñez, Diego Francisco Benitez Chao, Elsa N Garza-Treviño, Patricio Adrián Zapata-Morin, Gerardo R Padilla-Rivas, Jose Francisco Isla. Is the Cis-Element CACCC-Box a Master Regulatory Element during Cardiovascular Disease? A Bioinformatics Approach from the Perspective of the Krüppel-like Family of Transcription Factors. Life (Basel, Switzerland). vol 14. issue 4. 2024-04-27. PMID:38672763. |
our analysis reveals klf's interactions with gata4, mef2c, nkx2.5 and other ~90 potential genes that participate in the regulation of the hypertrophic environment (or cvds' environment). |
2024-04-27 |
2024-04-29 |
Not clear |
| Katrin Zlabinger, Andreas Spannbauer, Denise Traxler, Alfred Gugerell, Dominika Lukovic, Johannes Winkler, Julia Mester-Tonczar, Bruno Podesser, Mariann Gyöngyös. MiR-21, MiR-29a, GATA4, and MEF2c Expression Changes in Endothelin-1 and Angiotensin II Cardiac Hypertrophy Stimulated Isl-1 Cells. vol 8. issue 11. 2020-07-06. PMID:31717562. |
mir-21, mir-29a, gata4, and mef2c expression changes in endothelin-1 and angiotensin ii cardiac hypertrophy stimulated isl-1 cost- and time-intensive porcine translational disease models offer great opportunities to test drugs and therapies for pathological cardiac hypertrophy and can be supported by porcine cell culture models that provide further insights into basic disease mechanisms. |
2020-07-06 |
2023-08-13 |
Not clear |
| Ming Liu, Yumei Chen, Guixian Song, Bin Chen, Lihua Wang, Xing Li, Xiangqing Kong, Yahui Shen, Lingmei Qia. MicroRNA-29c overexpression inhibits proliferation and promotes apoptosis and differentiation in P19 embryonal carcinoma cells. Gene. vol 576. issue 1 Pt 2. 2016-04-21. PMID:26484393. |
we evaluated proliferation and cell cycle progression, detected morphological changes; apoptosis rate; bax, bcl2, gata binding protein 4 (gata4), cardiac troponin t (ctnt), and myocyte enhancer factor 2c (mef2c) expression; and caspase-3, -8, and -9 activity in mir-29c-overexpressing p19 cells, and investigated whether wnt4 was a mir-29c target. |
2016-04-21 |
2023-08-13 |
Not clear |
| Xiefan Fang, Jourdon Robinson, John Wang-Hu, Lingli Jiang, Daniel A Freeman, Scott A Rivkees, Christopher C Wendle. cAMP induces hypertrophy and alters DNA methylation in HL-1 cardiomyocytes. American journal of physiology. Cell physiology. vol 309. issue 6. 2015-12-04. PMID:26224577. |
elevated camp levels increased cell size and altered expression levels of cardiac genes and micro-rnas associated with hypertrophic cardiomyopathy (hcm), including myh6, myh7, myh7b, tnni3, anp, bnp, gata4, mef2c, mef2d, nfatc1, mir208a, and mir208b. |
2015-12-04 |
2023-08-13 |
mouse |
| Vicente Castro, Barbara Grisdale-Helland, Ståle J Helland, Jacob Torgersen, Torstein Kristensen, Guy Claireaux, Anthony P Farrell, Harald Takl. Cardiac molecular-acclimation mechanisms in response to swimming-induced exercise in Atlantic salmon. PloS one. vol 8. issue 1. 2013-07-26. PMID:23372811. |
higher protein levels of pcna were indicative of cardiac growth being driven by cardiomyocyte hyperplasia, while elevated cardiac mrna levels of mef2c, gata4 and acta1 suggested cardiomyocyte hypertrophy. |
2013-07-26 |
2023-08-12 |
Not clear |
| Lilin Zhong, Jing Zhu, Tiewei Lv, Guozhen Chen, Huichao Sun, Xuefang Yang, Xupei Huang, Jie Tia. Ethanol and its metabolites induce histone lysine 9 acetylation and an alteration of the expression of heart development-related genes in cardiac progenitor cells. Cardiovascular toxicology. vol 10. issue 4. 2011-03-04. PMID:20811785. |
moreover, high levels of ethanol and acetate significantly augmented the expression of gata4 and mef2c. |
2011-03-04 |
2023-08-12 |
rat |
| Lilin Zhong, Jing Zhu, Tiewei Lv, Guozhen Chen, Huichao Sun, Xuefang Yang, Xupei Huang, Jie Tia. Ethanol and its metabolites induce histone lysine 9 acetylation and an alteration of the expression of heart development-related genes in cardiac progenitor cells. Cardiovascular toxicology. vol 10. issue 4. 2011-03-04. PMID:20811785. |
the goal of current study is to investigate the effect of ethanol and its metabolites on h3ack9 acetylation and the mrna expression of heart development-related genes (gata4, mef2c, and tbx5) in cardiac progenitor cells. |
2011-03-04 |
2023-08-12 |
rat |
| Narasimman Gurusamy, Subhendu Mukherjee, Istvan Lekli, Claudia Bearzi, Silvana Bardelli, Dipak K Da. Inhibition of ref-1 stimulates the production of reactive oxygen species and induces differentiation in adult cardiac stem cells. Antioxidants & redox signaling. vol 11. issue 3. 2010-03-01. PMID:18717627. |
cardiac differentiation markers (nkx2.5, mef2c, and gata4), and cell death by apoptosis were significantly elevated in ref-1 sirna followed by h2o2-treated stem cells. |
2010-03-01 |
2023-08-12 |
Not clear |
| K Takebayashi-Suzuki, L B Pauliks, Y Eltsefon, T Mikaw. Purkinje fibers of the avian heart express a myogenic transcription factor program distinct from cardiac and skeletal muscle. Developmental biology. vol 234. issue 2. 2001-07-26. PMID:11397008. |
during this change in transcription, however, purkinje fibers continue to express cardiac muscle transcription factors, such as nkx2.5, gata4, and mef2c. |
2001-07-26 |
2023-08-12 |
Not clear |