| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Vincenzo Fiorentino, Maurizio Martini, Cosimo Galletti, Cristina Pizzimenti, Mariausilia Franchina, Antonio Ieni, Guido Fadda, Bruno Galletti, Giovanni Tuccar. The Morphology of Nasal Polyps in Different Age Groups: Histopathological Features. Journal of personalized medicine. vol 14. issue 4. 2024-04-27. PMID:38673041. |
nasal polyps (nps) represent the end-stage manifestation of chronic rhinosinusitis (crs), a relatively common pathological condition encountered in all ages of life. |
2024-04-27 |
2024-04-29 |
Not clear |
| Matteo Gelardi, Rossana Giancaspro, Vitaliano Nicola Quaranta, Emanuel La Gatta, Annamaria Ruzza, Michele Cassan. Dupilumab's impact on nasal citology: Real life experience after 1 year of treatment. American journal of otolaryngology. vol 45. issue 4. 2024-04-04. PMID:38574514. |
however, in most studies, the response to treatment is evaluated in terms of improvement in nasal polyp score (nps) or in sino-nasal outcome test (snot-22) scores. |
2024-04-04 |
2024-04-07 |
Not clear |
| Jiunn-Min Shieh, Yih-Jeng Tsai, Ming-Chieh Ma, Chih-Li Chen, Wen-Bin W. The cyclooxygenase-2 upregulation mediates production of PGE2 autacoid to positively regulate interleukin-6 secretion in chronic rhinosinusitis with nasal polyps and polyp-derived fibroblasts. Scientific reports. vol 14. issue 1. 2024-03-30. PMID:38555391. |
chronic rhinosinusitis (crs) can be traditionally classified as crswnp [with nasal polyps (nps)] and crssnp (without nps) based on the clinical phenotypes but recently suggested to be classified by the endotypes. |
2024-03-30 |
2024-04-02 |
human |
| Jiunn-Min Shieh, Yih-Jeng Tsai, Ming-Chieh Ma, Chih-Li Chen, Wen-Bin W. The cyclooxygenase-2 upregulation mediates production of PGE2 autacoid to positively regulate interleukin-6 secretion in chronic rhinosinusitis with nasal polyps and polyp-derived fibroblasts. Scientific reports. vol 14. issue 1. 2024-03-30. PMID:38555391. |
the cox-2 protein and mrna expression was found higher in nps than that in the control and crssnp patients' nasal tissues, mainly located at the epithelium and subepithelial stroma. |
2024-03-30 |
2024-04-02 |
human |
| Kyung Won Kwon, Seong Hyeon Park, Dong Hoon Lee, Dong-Young Kim, Il-Ho Park, Hyun-Jin Cho, Jong Seung Kim, Joo Yeon Kim, Sang Duk Hong, Shin Ae Kim, Shin Hyuk Yoo, Soo Kyoung Park, Sung Jae Heo, Sung Hee Kim, Tae-Bin Won, Woo Ri Choi, Yong Min Kim, Yong Wan Kim, Jong-Yeup Kim, Jae Hwan Kwon, Myeong Sang Y. Deep learning algorithm for the automated detection and classification of nasal cavity mass in nasal endoscopic images. PloS one. vol 19. issue 3. 2024-03-13. PMID:38478548. |
therefore, we aimed to develop an endoscopic-examination-based deep learning model to detect and classify nasal cavity mass lesions, including nasal polyps (nps), benign tumors, and malignant tumors. |
2024-03-13 |
2024-03-16 |
Not clear |
| Yilin Hou, Changhui Chen, Zhengqi Li, Tong Lu, Lin Sun, Yi Wei, Jian Li, Weiping We. Comparing Protein and Gene Expression Signature between Nasal Polyps and Nasal Fluids in Chronic Rhinosinusitis. International archives of allergy and immunology. vol 185. issue 3. 2024-03-03. PMID:38029733. |
we aimed to compare the protein and mrna inflammation signature between nasal polyps (nps) and nfs. |
2024-03-03 |
2024-03-06 |
Not clear |
| Zhichen Liu, Yuxu Yao, Huanxia Xie, Aina Zhou, Yuhui Fan, Jisheng Liu, Qingqing Jia. Visual and bibliometric analysis of chronic rhinosinusitis and nasal polyps. The journal of allergy and clinical immunology. Global. vol 3. issue 2. 2024-02-29. PMID:38419685. |
nasal polyps (nps) are one of the main manifestations that cause diverse clinical symptoms of crs. |
2024-02-29 |
2024-03-02 |
Not clear |
| Anna S Hoffmann, Christian S Betz, Robert Böscke, Rainer K Webe. [Decision-making in the treatment of chronic rhinosinusitis with nasal polyps in the era of biologics]. HNO. 2024-02-20. PMID:38376799. |
biologics that act on the type 2 inflammatory pathway led to a reduction in the nasal polyp score (nps), an improvement in nasal obstruction, and an improvement in quality of life without significant side effects. |
2024-02-20 |
2024-02-22 |
Not clear |
| Hevi Wihadmadyatami, Muhammad Ali Zulfikar, Herawati Herawati, Dyah Ayu O A Pratama, Golda Rani Saragih, Ulayatul Kustiati, And Nurrahmi Handayan. Chitosan hydrogel nanoparticle enhance therapeutic effect of bovine umbilical mesenchymal stem cell conditioned medium on canine cognitive dysfunction or canine Alzheimer's like mediated by inhibition of neuronal apoptotic. Open veterinary journal. vol 13. issue 12. 2024-01-31. PMID:38292722. |
nps shown upgraded drug take-up to the brain with decreased side impacts due to their drawn out contact time with the nasal mucosa, surface charge, nanosize, and capacity to extend the tight intersections inside the mucosa. |
2024-01-31 |
2024-02-02 |
human |
| Nicola Lombardo, Giovanna Lucia Piazzetta, Nadia Lobello, Giuseppe Cicala, Maria Patafi, Anna Teresa Benincasa, Corrado Pelaia, Emanuela Chiarella, Girolamo Pelai. Real-Life Effects of Omalizumab on Chronic Rhinosinusitis with Nasal Polyposis. Journal of personalized medicine. vol 14. issue 1. 2024-01-26. PMID:38276218. |
the inclusion criteria considered were as follows: 18 years of age, with a diagnosis of chronic rhinosinusitis with severe nasal polyposis expressed by an nps greater than or equal to 5 and/or a snot-22 greater than or equal to 50. |
2024-01-26 |
2024-01-28 |
Not clear |
| Michael Donkor, Jamie Y Choe, Danielle Marie Reid, Hope K Fiadjoe, Byron Quinn, Amalendu Ranjan, Mark Pulse, Pankaj Chaudhary, Riyaz Basha, Harlan P Jone. Surgical Primary Tumor Resection Reduces Accumulation of CD11b Pharmaceuticals (Basel, Switzerland). vol 17. issue 1. 2024-01-23. PMID:38256885. |
we found that our nasal nano-vaccine (cpg-np-tag), compared to control nps administered after primary mammary tumor resection, significantly reduced lung metastasis in female balb/c mice subjected to surgery (surgery mice). |
2024-01-23 |
2024-01-25 |
mouse |
| Rasads Misirovs, Rory Chan, Brian Lipwort. SNOT-5 and SNOT-22 relationship with endoscopic and radiological scores in chronic rhinosinusitis with nasal polyps. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 2023-11-20. PMID:37984707. |
objective findings of nasal polyps and paranasal sinus inflammation are commonly graded using nasal polyp score (nps) and lund-mackay score (lms), respectively. |
2023-11-20 |
2023-11-29 |
Not clear |
| Cosimo Galletti, Martina Ragusa, Federico Sireci, Francesco Ciodaro, Maria Antonietta Barbieri, Giorgia Giunta, Egle Grigaliute, Angelo Immordino, Francesco Lorusso, Francesco Dispenza, Francesco Freni, Francesco Galletti, Salvatore Gallina, Igo La Mantia, Bruno Gallett. Dupilumab in chronic rhinosinusitis with nasal polyps: Real life data in a multicentric Sicilian experience. American journal of otolaryngology. vol 45. issue 1. 2023-11-10. PMID:37948824. |
this study aimed to evaluate the effectiveness and safety of dupilumab during the first year of treatment in a real-life setting, focusing on improvement in nasal polyp score (nps) as well as specific symptoms, quality of life and olfactory function. |
2023-11-10 |
2023-11-20 |
Not clear |
| Jiaxin Li, Huan Peng, Wen Zhang, Muzi Li, Nan Wang, Chen Peng, Xinyue Zhang, Yan L. Enhanced Nose-to-Brain Delivery of Combined Small Interfering RNAs Using Lesion-Recognizing Nanoparticles for the Synergistic Therapy of Alzheimer's Disease. ACS applied materials & interfaces. 2023-11-08. PMID:37939350. |
after intranasal administration, the lesion-recognizing nps cross the nasal mucosa and migrate to the affected brain areas. |
2023-11-08 |
2023-11-20 |
mouse |
| Helena Moratin, Anna Thöle, Josephine Lang, Totta Ehret Kasemo, Manuel Stöth, Rudolf Hagen, Agmal Scherzad, Stephan Hackenber. Ag- but Not ZnO-Nanoparticles Disturb the Airway Epithelial Barrier at Subtoxic Concentrations. Pharmaceutics. vol 15. issue 10. 2023-10-30. PMID:37896266. |
in the nasal respiratory epithelium, cells of the mucosa represent one of the first contact points of the human organism with airborne nps. |
2023-10-30 |
2023-11-08 |
human |
| Hiroatsu Hatsukawa, Masaaki Ishikawa, Tomoyuki Hirai, Kazuo Endo, Emiko Saito, Hirotaka Matsumoto, Kouya Okazak. Comorbidity of eosinophilic chronic rhinosinusitis in chronic eosinophilic pneumonia. Respirology case reports. vol 11. issue 11. 2023-10-20. PMID:37854459. |
nasal polyps (nps) were observed in 50% of patients on endoscopy. |
2023-10-20 |
2023-11-08 |
Not clear |
| Mohamed M Badran, Abdulrahman E Alanazi, Mohamed Abbas Ibrahim, Doaa Hasan Alshora, Ehab Taha, Abdullah H Alomran. Optimization of Bromocriptine-Mesylate-Loaded Polycaprolactone Nanoparticles Coated with Chitosan for Nose-to-Brain Delivery: In Vitro and In Vivo Studies. Polymers. vol 15. issue 19. 2023-10-14. PMID:37835942. |
this study aimed to formulate chitosan (cs)-coated poly ε-caprolactone nanoparticles (pcl nps) loaded with bm for direct targeting to the brain via the nasal route. |
2023-10-14 |
2023-10-15 |
Not clear |
| Mohamed M Badran, Abdulrahman E Alanazi, Mohamed Abbas Ibrahim, Doaa Hasan Alshora, Ehab Taha, Abdullah H Alomran. Optimization of Bromocriptine-Mesylate-Loaded Polycaprolactone Nanoparticles Coated with Chitosan for Nose-to-Brain Delivery: In Vitro and In Vivo Studies. Polymers. vol 15. issue 19. 2023-10-14. PMID:37835942. |
the bm-cs-pcl nps displayed a biphasic release pattern, with an initial rapid drug release lasting for 2 h, followed by a sustained release for up to 48 h. the 0.25% cs-coated bm-cs-pcl nps showed a high level of permeation across the goat nasal mucosa, with reasonable mucoadhesive strength. |
2023-10-14 |
2023-10-15 |
Not clear |
| Mohamed M Badran, Abdulrahman E Alanazi, Mohamed Abbas Ibrahim, Doaa Hasan Alshora, Ehab Taha, Abdullah H Alomran. Optimization of Bromocriptine-Mesylate-Loaded Polycaprolactone Nanoparticles Coated with Chitosan for Nose-to-Brain Delivery: In Vitro and In Vivo Studies. Polymers. vol 15. issue 19. 2023-10-14. PMID:37835942. |
these findings suggested that the optimized 0.25% cs-coated bm-cs-pcl nps hold promise for successful nasal delivery, thereby improving the therapeutic efficacy of bm. |
2023-10-14 |
2023-10-15 |
Not clear |
| Giovanna Lucia Piazzetta, Nadia Lobello, Emanuela Chiarella, Alberta Rizzuti, Corrado Pelaia, Girolamo Pelaia, Nicola Lombard. Targeting IL-4 and IL-13 Receptors on Eosinophils in CRSwNP Patients: The Clinical Efficacy of Dupilumab. Journal of personalized medicine. vol 13. issue 9. 2023-09-28. PMID:37763171. |
the inclusion criteria were: age ≥ 18 years; confirmed diagnosis of chronic rhinosinusitis with severe nasal polyposis; disease severity with nps nasal polyposis endoscopic score total score ≥ 5 and/or snot-22 ≥ 50; previous treatment failure due to lack of efficacy or discontinuation of systemic corticosteroid therapy and/or non-response or recurrence following surgery. |
2023-09-28 |
2023-10-07 |
Not clear |