| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tiago Chaves, Bibiána Török, Csilla Lea Fazekas, Pedro Correia, Eszter Sipos, Dorottya Várkonyi, Zsuzsanna E Tóth, Fanni Dóra, Árpád Dobolyi, Dóra Zelen. The Dopaminergic Cells in the Median Raphe Region Regulate Social Behavior in Male Mice. International journal of molecular sciences. vol 25. issue 8. 2024-04-27. PMID:38673899. |
besides serotonin, there have also been reports of a small population of dopaminergic neurons in this region. |
2024-04-27 |
2024-04-29 |
mouse |
| Laura Boi, Gilberto Fison. Investigating affective neuropsychiatric symptoms in rodent models of Parkinson's disease. International review of neurobiology. vol 174. 2024-02-10. PMID:38341228. |
depression, anxiety, and apathy are often treated with conventional medications, including selective serotonin reuptake inhibitors, tricyclic antidepressants, and dopaminergic agonists. |
2024-02-10 |
2024-02-14 |
Not clear |
| Bruno P Guiard, Guillaume Gott. The High-Precision Liquid Chromatography with Electrochemical Detection (HPLC-ECD) for Monoamines Neurotransmitters and Their Metabolites: A Review. Molecules (Basel, Switzerland). vol 29. issue 2. 2024-01-26. PMID:38276574. |
this review highlights the advantages of high-precision liquid chromatography with an electrochemical detector (hplc-ecd) in detecting and quantifying biological samples obtained through intracerebral microdialysis, specifically the serotonergic and dopaminergic systems: serotonin (5-ht), 5-hydroxyindolacetic acid (5-hiaa), 3,4-dihydroxyphenylacetic acid (dopac), dopamine (da), 3-metoxytryptamin (3-mt) and homovanillic acid (hva). |
2024-01-26 |
2024-01-28 |
Not clear |
| Elena Kotsyuba, Arman Pahlevaniane, Sergei Maslennikov, Vyacheslav Dyachu. Development of Serotonergic and Dopaminergic Neuronal Networks of the Central Nervous System in King Crab, Biology. vol 13. issue 1. 2024-01-22. PMID:38248466. |
development of serotonergic and dopaminergic neuronal networks of the central nervous system in king crab, this article presents recent findings as regards distribution of cells producing serotonin and dopamine in the larval central nervous system at different developmental stages, including four pelagic larval stages (zoea i-iv), a semibenthic postlarval stage glaucothoe (megalopa), benthic juveniles, and adult red king crabs, |
2024-01-22 |
2024-01-24 |
Not clear |
| Jorge-Enrique Maximiliano, Irma Ares, Marta Martínez, Bernardo Lopez-Torres, María-Rosa Martínez-Larrañaga, Arturo Anadón, María-Aránzazu Martíne. Dopaminergic and serotoninergic systems as preferential targets of the pyrethroid tefluthrin exposure in the rat brain. Environmental research. 2024-01-20. PMID:38244974. |
tefluthrin could modify brain monoamine neurotransmitters, da and 5-ht levels as well as dopaminergic and serotoninergic signaling pathways. |
2024-01-20 |
2024-01-23 |
rat |
| Nune Darbinian, Nana Merabova, Gabriel Tatevosian, Mary Morrison, Armine Darbinyan, Huaqing Zhao, Laura Goetzl, Michael Edgar Selze. Biomarkers of Affective Dysregulation Associated with In Utero Exposure to EtOH. Cells. vol 13. issue 1. 2024-01-11. PMID:38201206. |
however, we postulate that, more likely, the affective dysregulation is associated with the effects of etoh exposure on the development of fetal serotonergic (5-ht) and/or dopaminergic (da) pathways, i.e., pathways that in postnatal life are believed to regulate mood. |
2024-01-11 |
2024-01-13 |
Not clear |
| Yunjiang Yu, Shihui Tan, Hongzhi Guo, Xin Hua, Haibo Chen, Yue Yang, Dongli Xie, Chuan Yi, Haibo Ling, Mingdeng Xian. Chronic neurotoxicity of Tetrabromobisphenol A: Induction of oxidative stress and damage to neurons in Caenorhabditis elegans. Chemosphere. 2024-01-07. PMID:38185427. |
furthermore, 100 μg/l tcbpa exposure caused a reduction in dopamine and serotonin levels, and damage in dopaminergic and serotoninergic neurons, which was further confirmed by the downregulated expression of related genes (e.g., dop-1, dop-3, cat-1, and mod-1). |
2024-01-07 |
2024-01-10 |
caenorhabditis_elegans |
| Sarita Pyatha, Haesoo Kim, Daeun Lee, Kisok Ki. Co-exposure to lead, mercury, and cadmium induces neurobehavioral impairments in mice by interfering with dopaminergic and serotonergic neurotransmission in the striatum. Frontiers in public health. vol 11. 2023-12-01. PMID:38026429. |
in conclusion, this study demonstrates that simultaneous exposure to different metals can impact key enzymes involved in dopaminergic and serotonergic neurotransmission processes, leading to disruptions in dopamine and serotonin homeostasis and consequently a range of detrimental neurobehavioral effects. |
2023-12-01 |
2023-12-10 |
mouse |
| Dmitrii S Traktirov, Ilya R Nazarov, Valeria S Artemova, Raul R Gainetdinov, Nina S Pestereva, Marina N Karpenk. Alterations in Serotonin Neurotransmission in Hyperdopaminergic Rats Lacking the Dopamine Transporter. Biomedicines. vol 11. issue 11. 2023-11-25. PMID:38001881. |
the observed region-specific changes in the tissue levels of serotonin and in the expression of dopamine and serotonergic metabolism enzymes in rats with an excess of dopamine can indicate important consequences for the pharmacotherapy of drugs that modulate the dopaminergic system. |
2023-11-25 |
2023-11-28 |
rat |
| Adela G Buciuc, Paula Traugott, Carlos R Dange. An Unusual Presentation of Serotonin Syndrome and Subsequent Catatonia in a Patient With a Family History of Huntington's Disease. Cureus. vol 15. issue 9. 2023-09-18. PMID:37720123. |
neuroleptic malignant syndrome (nms) and serotonin syndrome (ss) represent serious life-threatening conditions that share phenotypic and pathophysiologic features due to intricate interactions between the dopaminergic and serotoninergic systems. |
2023-09-18 |
2023-10-07 |
Not clear |
| Natalia F Sardi, Ana C Pescador, Evellyn M Azevedo, José A Pochapski, Caroline Kukolj, Katherinne M Spercoski, Anderson J M Andrade, Claudio da Cunha, Luana Fische. Sleep and pain: a role for the anterior cingulate cortex, nucleus accumbens and dopamine in the increased pain sensitivity following sleep restriction. The journal of pain. 2023-09-06. PMID:37673193. |
data on indirect dopaminergic parameters, dat glycosylation and darpp-32 phosphorylation, as well as dopamine, serotonin and norepinephrine levels, suggest that dopaminergic function decreases in the nucleus accumbens and anterior cingulate cortex after sleep restriction. |
2023-09-06 |
2023-10-07 |
rat |
| Licia Vellucci, Mariateresa Ciccarelli, Elisabetta Filomena Buonaguro, Michele Fornaro, Giordano D'Urso, Giuseppe De Simone, Felice Iasevoli, Annarita Barone, Andrea de Bartolomei. The Neurobiological Underpinnings of Obsessive-Compulsive Symptoms in Psychosis, Translational Issues for Treatment-Resistant Schizophrenia. Biomolecules. vol 13. issue 8. 2023-08-26. PMID:37627285. |
an integrative view exploring this topic should take into account the following aspects: (i) the implication for glutamate, dopamine, and serotonin neurotransmission as demonstrated by genetic findings; (ii) the growing neuroimaging evidence of the common brain regions and dysfunctional circuits involved in both diseases; (iii) the pharmacological modulation of dopaminergic, serotoninergic, and glutamatergic systems as current therapeutic strategies in schizophrenia ocs; (iv) the recent discovery of midbrain dopamine neurons and dopamine d1- and d2-like receptors as orchestrating hubs in repetitive and psychotic behaviors; (v) the contribution of n-methyl-d-aspartate receptor subunits to both psychosis and ocd neurobiology. |
2023-08-26 |
2023-09-07 |
Not clear |
| Efthalia Angelopoulou, Evangelia Stanitsa, Claire Chrysanthi Karpodini, Anastasia Bougea, Dionysia Kontaxopoulou, Stella Fragkiadaki, Christos Koros, Vasiliki Epameinondas Georgakopoulou, George Fotakopoulos, Yiannis Koutedakis, Christina Piperi, Sokratis G Papageorgio. Pharmacological and Non-Pharmacological Treatments for Depression in Parkinson's Disease: An Updated Review. Medicina (Kaunas, Lithuania). vol 59. issue 8. 2023-08-26. PMID:37629744. |
available pharmacological therapeutic options for depression in pd mainly include selective serotonin reuptake inhibitors, serotonin and norepinephrine reuptake inhibitors, and tricyclic antidepressants; meanwhile, agents acting on dopaminergic pathways used for motor symptoms, such as levodopa, dopaminergic agonists, and monoamine oxidase b (mao-b) inhibitors, may also provide beneficial antidepressant effects. |
2023-08-26 |
2023-09-07 |
Not clear |
| Can Tao, Guang-Wei Zhang, Junxiang J Huang, Zhong Li, Huizhong W Tao, Li I Zhan. The medial preoptic area mediates depressive-like behaviors induced by ovarian hormone withdrawal through distinct GABAergic projections. Nature neuroscience. 2023-07-31. PMID:37524978. |
these projections enhance activity of dopaminergic neurons in the vta and serotonergic neurons in the dorsal raphe, respectively, with increased release of dopamine and serotonin, possibly through disinhibition mechanisms. |
2023-07-31 |
2023-08-14 |
mouse |
| Chuanqi Chu, Tiantian Li, Leilei Yu, Yiwen Li, Miaoyu Li, Min Guo, Jianxin Zhao, Qixiao Zhai, Fengwei Tian, Wei Che. A Low-Protein, High-Carbohydrate Diet Exerts a Neuroprotective Effect on Mice with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-Induced Parkinson's Disease by Regulating the Microbiota-Metabolite-Brain Axis and Fibroblast Growth Factor 21. Journal of agricultural and food chemistry. 2023-06-02. PMID:37267589. |
here, we found that an lphc diet ameliorated 1-methyl-4-phenyl-1,2,3,6-tetrathydropyridine (mptp)-induced motor deficits, decreased dopaminergic neuronal death, and increased the levels of striatal dopamine, serotonin, and their metabolites in pd mice. |
2023-06-02 |
2023-08-14 |
mouse |
| Marianna Mazza, Georgios Demetrios Kotzalidis, Giuseppe Marano, Domenico De Berardis, Giovanni Martinotti, Enrico Romagnoli, Giuseppe Biondi-Zoccai, Antonio Abbate, Gabriele San. Lorcaserin: worthy of further insights? Results from recent research. CNS & neurological disorders drug targets. 2023-04-03. PMID:37005521. |
lorcaserin is a 3-benzazepine that binds 5-ht2c serotonin receptors in the hypothalamus, where it mediates lack of hunger and/or satiety, and in the ventral tegmental area, the site of origin of the mesolimbic and mesocortical dopaminergic projections, which mediate pleasure and reward. |
2023-04-03 |
2023-08-14 |
Not clear |
| You-Peng Fu, Yun Wan. Amphetamines abuse and depression: Focus on TRPC channels. Experimental neurology. 2023-03-30. PMID:36996966. |
amphetamines abuse can damage dopaminergic and serotonin neurons and cause neuroinflammation and neurotoxicity. |
2023-03-30 |
2023-08-14 |
Not clear |
| Renata Matraszek-Gawron, Mirosława Chwil, Karol Terlecki, Michał Marian Skoczyla. Current Knowledge of the Antidepressant Activity of Chemical Compounds from Pharmaceuticals (Basel, Switzerland). vol 16. issue 1. 2023-03-08. PMID:36678554. |
this systematic review on antidepressant compounds in saffron crocus and their mechanisms of action and side effects is based on publications released between 1995−2022 and data indexed in 15 databases under the following search terms: antidepressant effect, central nervous system, crocus sativus, cognitive impairement, crocin, crocetin, depression, dopamine, dopaminergic and serotonergic systems, picrocrocin, phytotherapy, neurotransmitters, safranal, saffron, serotonin, and biologically active compounds. |
2023-03-08 |
2023-08-16 |
Not clear |
| Elisa Giunti, Roberto Collu, Simona Dedoni, M Paola Castelli, Maria Scherma, Paola Fadd. Food restriction and hyperactivity induce changes in corticolimbic brain dopamine and serotonin levels in female rats. Behavioural brain research. 2023-03-02. PMID:36863461. |
we exposed female rats to the aba paradigm and measured the levels of da, 5-ht, and the metabolites 3,4-dihydroxyphenylacetic acid (dopac), homovanillic acid (hva), 5-hydroxyindoleacetic acid (5-hiaa), and dopaminergic type 2 (d2) receptors density in feeding- and reward-implicated brain regions (i.e., cerebral cortex, cx; prefrontal cortex, pfc; caudate putamen, cpu; nucleus accumbens, nacc; amygdala, amy; hypothalamus, hyp; hippocampus, hipp). |
2023-03-02 |
2023-08-14 |
rat |
| Yuma Nagai, Yuri Kisaka, Kento Nomura, Naoya Nishitani, Chihiro Andoh, Masashi Koda, Hiroyuki Kawai, Kaoru Seiriki, Kazuki Nagayasu, Atsushi Kasai, Hisashi Shirakawa, Takanobu Nakazawa, Hitoshi Hashimoto, Shuji Kanek. Dorsal raphe serotonergic neurons preferentially reactivate dorsal dentate gyrus cell ensembles associated with positive experience. Cell reports. vol 42. issue 3. 2023-02-23. PMID:36821440. |
furthermore, we revealed that dopaminergic signaling induced by activation of drn 5-ht neurons projecting to the ventral tegmental area mediates an increase in active coping behavior and positive ddg ensemble reactivation. |
2023-02-23 |
2023-08-14 |
Not clear |