| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Karima Schwab, Dilyara Lauer, Mandy Magbagbeolu, Franz Theuring, Anna Gasiorowska, Maciej Zadrozny, Charles R Harrington, Claude M Wischik, Grażyna Niewiadomska, Gernot Riede. Hydromethylthionine rescues synaptic SNARE proteins in a mouse model of tauopathies: interference by cholinesterase inhibitors. Brain research bulletin. 2024-04-27. PMID:38677558. |
interference of cholinesterase inhibition with hmtm was observed also in a tau transgenic mouse model, where rivastigmine reduced the pharmacological activity of hmtm at multiple brain levels including hippocampal acetylcholine release, synaptosomal glutamate release and mitochondrial activity. |
2024-04-27 |
2024-04-30 |
mouse |
| Jun-Meng Wang, Yue-Mei Wang, Yuan-Bing Zhu, Chan Cui, Tong Feng, Qin Huang, Shu-Qing Liu, Qiao-Feng W. Peripheral inflammation triggering central anxiety through the hippocampal glutamate metabolized receptor 1. CNS neuroscience & therapeutics. vol 30. issue 4. 2024-04-27. PMID:38676295. |
peripheral inflammation triggering central anxiety through the hippocampal glutamate metabolized receptor 1. |
2024-04-27 |
2024-04-29 |
mouse |
| Stefan Passlick, Ghanim Ullah, Christian Henneberge. Bidirectional dysregulation of synaptic glutamate signaling after transient metabolic failure. bioRxiv : the preprint server for biology. 2024-04-22. PMID:38645213. |
we modelled acute and transient metabolic failure by using a chemical ischemia protocol and analyzed its effect on glutamatergic synaptic transmission and extracellular glutamate signals by electrophysiology and multiphoton imaging, respectively, in the hippocampus. |
2024-04-22 |
2024-04-24 |
Not clear |
| Zohreh Zare, Sakineh Shafia, Moslem Mohammad. Thyroid hormone deficiency affects anxiety-related behaviors and expression of hippocampal glutamate transporters in male congenital hypothyroid rat offspring. Hormones and behavior. vol 162. 2024-04-18. PMID:38636205. |
thyroid hormone deficiency affects anxiety-related behaviors and expression of hippocampal glutamate transporters in male congenital hypothyroid rat offspring. |
2024-04-18 |
2024-04-21 |
rat |
| Zohreh Zare, Sakineh Shafia, Moslem Mohammad. Thyroid hormone deficiency affects anxiety-related behaviors and expression of hippocampal glutamate transporters in male congenital hypothyroid rat offspring. Hormones and behavior. vol 162. 2024-04-18. PMID:38636205. |
we aimed to examine the consequences of thyroid hormone deficiency on anxiety-related behaviors and protein expression of hippocampal glutamate transporters in congenital hypothyroid male offspring rats. |
2024-04-18 |
2024-04-21 |
rat |
| Zohreh Zare, Sakineh Shafia, Moslem Mohammad. Thyroid hormone deficiency affects anxiety-related behaviors and expression of hippocampal glutamate transporters in male congenital hypothyroid rat offspring. Hormones and behavior. vol 162. 2024-04-18. PMID:38636205. |
thereafter, protein expression of astrocytic (glast and glt-1) and neuronal (eaac1) glutamate transporters were measured in the hippocampus by immunoblotting. |
2024-04-18 |
2024-04-21 |
rat |
| Zohreh Zare, Sakineh Shafia, Moslem Mohammad. Thyroid hormone deficiency affects anxiety-related behaviors and expression of hippocampal glutamate transporters in male congenital hypothyroid rat offspring. Hormones and behavior. vol 162. 2024-04-18. PMID:38636205. |
our findings indicate that thyroid hormone deficiency was associated with alterations in protein expression of glutamate transporters in the hippocampus. |
2024-04-18 |
2024-04-21 |
rat |
| Han-Ying Wang, Hiroshi Takagi, Patrick N Stoney, Anai Echeverria, Bernd Kuhn, Kuei-Sen Hsu, Tomoyuki Takahash. Anoxia-induced hippocampal LTP is regeneratively produced by glutamate and nitric oxide from the neuro-glial-endothelial axis. iScience. vol 27. issue 4. 2024-04-09. PMID:38591010. |
anoxia-induced hippocampal ltp is regeneratively produced by glutamate and nitric oxide from the neuro-glial-endothelial axis. |
2024-04-09 |
2024-04-11 |
mouse |
| Sohrab Anvari, Mohammad Javan, Javad Mirnajafi-Zadeh, Yaghoub Fathollah. Repeated Morphine Exposure Alters Temporoamonic-CA1 Synaptic Plasticity in Male Rat Hippocampus. Neuroscience. 2024-03-21. PMID:38513764. |
in this study, the electrophysiological and biochemical consequences of repeated exposure to morphine in male rats on glutamatergic synaptic transmission, synaptic plasticity, the expression of gaba receptors and glutamate receptors at the temporoammonic-ca1 synapse along the longitudinal axis of the hippocampus (dorsal, intermediate, ventral, dh, ih, vh, respectively) were investigated. |
2024-03-21 |
2024-03-24 |
rat |
| Yanlan Long, Zhen Zhao, Wanting Xie, Jinhui Shi, Fengyu Yang, Dan Zhu, Ping Jiang, Qilong Tang, Zhou Ti, Bin Jiang, Xia Yang, Guoquan Gao, Weiwei Q. Kallistatin leads to cognition impairment via downregulating glutamine synthetase. Pharmacological research. 2024-03-16. PMID:38492829. |
baseline glutamate levels were elevated and miniature excitatory postsynaptic current (mepsc) frequency was increased in the hippocampus, suggesting the impairment of glutamate homeostasis in kal-tg mice. |
2024-03-16 |
2024-03-19 |
mouse |
| Peng Ren, Jing-Ya Wang, Hong-Lei Chen, Yue Wang, Lin-Yu Cui, Jing-Yao Duan, Wen-Zhi Guo, Yong-Qi Zhao, Yun-Feng L. Activation of σ-1 receptor mitigates estrogen withdrawal-induced anxiety/depressive-like behavior in mice via restoration of GABA/glutamate signaling and neuroplasticity in the hippocampus. Journal of pharmacological sciences. vol 154. issue 4. 2024-03-14. PMID:38485341. |
in the present study, excitatory/inhibitory signaling in the hippocampus was reflected by gaba and glutamate and their associated excitatory-inhibitory receptor proteins, the hpa axis hormones in the hippocampus were assessed by elisa. |
2024-03-14 |
2024-03-17 |
mouse |
| Alena O Burnyasheva, Natalia A Stefanova, Nataliya G Kolosova, Darya V Telegin. Changes in the Glutamate/GABA System in the Hippocampus of Rats with Age and during Alzheimer's Disease Signs Development. Biochemistry. Biokhimiia. vol 88. issue 12. 2024-03-10. PMID:38462444. |
here we analyzed the age-related alterations of the levels of glutamate, gaba, as well as enzymes that synthesize them (glutaminase, glutamine synthetase, gaba-t, and gad67), transporters (glast, glt-1, and gat1), and relevant receptors (glua1, nmdar1, nmda2b, and gabaar1) in the whole hippocampus of the wistar rats and of the senescence-accelerated oxys rats, a model of the most common (> 95%) sporadic ad. |
2024-03-10 |
2024-03-14 |
rat |
| Alena O Burnyasheva, Natalia A Stefanova, Nataliya G Kolosova, Darya V Telegin. Changes in the Glutamate/GABA System in the Hippocampus of Rats with Age and during Alzheimer's Disease Signs Development. Biochemistry. Biokhimiia. vol 88. issue 12. 2024-03-10. PMID:38462444. |
our results suggest that there is a decline in glutamate and gaba signaling with age in hippocampus of the both rat strains. |
2024-03-10 |
2024-03-14 |
rat |
| Kohei Takahashi, Kazuhiro Kurokawa, Kazuya Miyagawa, Atsumi Mochida-Saito, Hiroshi Takeda, Minoru Tsuj. Repeated antibiotic drug treatment negatively affects memory function and glutamatergic nervous system of the hippocampus in mice. Neuroscience letters. 2024-03-03. PMID:38432356. |
in our study, a mouse dysbiosis model showed impaired memory-related behavior in the passive avoidance test; decreased expression levels of glutaminase, excitatory amino acid transporter (eaat)1, eaat2, vesicular glutamate transporter 2, synaptophysin, brain-derived neurotrophic factor, doublecortin, neuronal nuclear protein, glial fibrillary acidic protein, and s100β; and decreased phosphorylation of n-methyl-d-aspartate receptor subunit 1, calmodulin-dependent protein kinase ii, α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor subunit 1, and camp response element-binding protein in the hippocampus. |
2024-03-03 |
2024-03-06 |
mouse |
| Dingding Lv, Bin Xiao, Huaying Liu, Linping Wang, Yingshun Li, Yin Hua Zhang, Qinghua Ji. Enhanced NMDA receptor pathway and glutamate transmission in the hippocampal dentate gyrus mediate the spatial learning and memory impairment of obese rats. Pflugers Archiv : European journal of physiology. 2024-02-28. PMID:38416255. |
enhanced nmda receptor pathway and glutamate transmission in the hippocampal dentate gyrus mediate the spatial learning and memory impairment of obese rats. |
2024-02-28 |
2024-03-01 |
rat |
| Dingding Lv, Bin Xiao, Huaying Liu, Linping Wang, Yingshun Li, Yin Hua Zhang, Qinghua Ji. Enhanced NMDA receptor pathway and glutamate transmission in the hippocampal dentate gyrus mediate the spatial learning and memory impairment of obese rats. Pflugers Archiv : European journal of physiology. 2024-02-28. PMID:38416255. |
since glutamatergic transmission and nmda receptor neural pathways in hippocampal dentate gyrus (dg) are essential in the learning and memory, we aimed to investigate glutamate (glu) and nmda receptor signaling of dg in spatial learning and memory in diet-induced obesity (dio) rats. |
2024-02-28 |
2024-03-01 |
rat |
| Shao-Hua Yang, Yuanhong Sun, Raymond Berry, Gourav Roy Choudhury, Ali Winters, Kiran Chaudhari, Ran Li. Glutamate Provides Cytoprotective Effect for Astrocytes Against Ischemic Insult and Promotes Astrogliosis. Aging and disease. 2024-02-20. PMID:38377020. |
the cytoprotective effect of glutamate appears to be astrocyte-specific, as glutamate dose-dependently induces cytotoxic action in murine hippocampal ht-22 cell line. |
2024-02-20 |
2024-02-23 |
Not clear |
| Nicholas Pintori, Alessandro Piva, Francesca Mottarlini, Fernando Castillo Díaz, Coralie Maggi, Lucia Caffino, Fabio Fumagalli, Cristiano Chiamuler. Brief exposure to enriched environment rapidly shapes the glutamate synapses in the rat brain: A metaplastic fingerprint. The European journal of neuroscience. 2024-02-20. PMID:38378276. |
adult male sprague-dawley rats were exposed to ee for 22 h and the expression of critical elements of the glutamate synapse was measured 2 h after the end of ee in the medial prefrontal cortex (mpfc), nucleus accumbens (nac) and hippocampus (hipp) brain areas, which are critical for reward and memory. |
2024-02-20 |
2024-02-23 |
rat |
| Niklas Reich, Christian Hölsche. Cholecystokinin (CCK): a neuromodulator with therapeutic potential in Alzheimer's and Parkinson's disease. Frontiers in neuroendocrinology. 2024-02-12. PMID:38346453. |
the neuropeptide facilitates hippocampal glutamate release and gates gabaergic basket cell activity, which improves declarative memory acquisition, but inhibits consolidation. |
2024-02-12 |
2024-02-15 |
Not clear |
| Christopher J E Denning, Lauren E Madory, Jessica N Herbert, Ryan A Cabrera, Karen K Szumlinsk. Neuropharmacological Evidence Implicating Drug-Induced Glutamate Receptor Dysfunction in Affective and Cognitive Sequelae of Subchronic Methamphetamine Self-Administration in Mice. International journal of molecular sciences. vol 25. issue 3. 2024-02-10. PMID:38339206. |
relative to naïve controls, ma-experienced mice exhibited several changes in the expression of certain glutamate receptor-related proteins and their downstream effectors within the ventral and dorsal areas of the prefrontal cortex, the hippocampus, and the amygdala, many of which were sex-selective. |
2024-02-10 |
2024-02-12 |
mouse |