| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rifat Jabeen, Nusrat Jan, Bazila Naseer, Prakash Kumar Sarangi, Kandi Sridhar, Praveen Kumar Dikkala, Maharshi Bhaswant, Syed Zameer Hussain, Baskaran Stephen Inbara. Development of Germinated-Brown-Rice-Based Novel Functional Beverage Enriched with γ-Aminobutyric Acid: Nutritional and Bio-Functional Characterization. Foods (Basel, Switzerland). vol 13. issue 8. 2024-04-27. PMID:38672954. |
γ-aminobutyric acid (gaba), recognized as a primary inhibitory neurotransmitter within the brain, serves a crucial role in the aging process and in neurodegenerative conditions such as alzheimer's disease. |
2024-04-27 |
2024-04-29 |
Not clear |
| Sara de la Salle, Justin Piche, Brittany Duncan, Joëlle Choueiry, Molly Hyde, Robert Aidelbaum, Ashley Baddeley, Danielle Impey, Noreen Rahmani, Vadim Ilivitsky, Verner Knot. Influence of GABA Journal of psychopharmacology (Oxford, England). 2024-04-22. PMID:38647196. |
influence of gaba dysfunctional sensory gating in anxiety disorders, indexed by the failure to inhibit the p50 event-related potential (erp) to repeated stimuli, has been linked to deficits in the major inhibitory neurotransmitter γ-aminobutyric acid (gaba). |
2024-04-22 |
2024-04-26 |
Not clear |
| Zhenyu Zhang, Hua Zhao, Xiaoling Chen, Gang Tian, Guangmang Liu, Jingyi Cai, Gang Ji. Enhancing pig growth and gut health with fermented Jatropha curcas cake: Impacts on microbiota, metabolites, and neurotransmitters. Journal of animal physiology and animal nutrition. 2024-04-22. PMID:38648292. |
moreover, fjcc5 significantly boosted circulating neurotransmitter levels of 5-ht (p = 0.006) and gaba (p = 0.002) in plasma and hypothalamus, with corresponding increases in precursor amino acids (p < 0.05). |
2024-04-22 |
2024-04-26 |
Not clear |
| Beverley A Orse. Discovering the Intriguing Properties of Extrasynaptic γ-Aminobutyric Acid Type A Receptors. Anesthesiology. 2024-04-16. PMID:38624275. |
briefly, the principal inhibitory neurotransmitter in the brain, γ-aminobutyric acid (gaba), was conventionally thought to regulate cognitive processes by activating synaptic gaba type a (gabaa) receptors and generating transient inhibitory synaptic currents. |
2024-04-16 |
2024-04-18 |
mouse |
| Xintong Li, Tong Zheng, Jiayi Zhang, Haibo Chen, Chongdan Xiang, Yanan Sun, Yao Dang, Ping Ding, Guocheng Hu, Yunjiang Y. Photoaged polystyrene microplastics result in neurotoxicity associated with neurotransmission and neurodevelopment in zebrafish larvae (Danio rerio). Environmental research. 2024-02-24. PMID:38401682. |
motor neuron development was disrupted by transgenic (hb9-gfp) zebrafish larvae exposed to a-ps, with significant alterations in neurotransmitter levels (ach, da, 5-ht, and gaba) and enzyme activity (ache, chat, and che). |
2024-02-24 |
2024-02-27 |
zebrafish |
| Nan Song, Zhenhong Liu, Yan Gao, Shanshan Lu, Shenglian Yang, Chao Yua. NAc-DBS corrects depression-like behaviors in CUMS mouse model via disinhibition of DA neurons in the VTA. Molecular psychiatry. 2024-02-16. PMID:38361128. |
moreover, even a single trial nac-dbs led to the elevation of the γ-aminobutyric acid (gaba) neurotransmitter, accompanied by the increase in dopamine (da) neuron activity in the vta. |
2024-02-16 |
2024-02-18 |
mouse |
| Navneet Dhaliwal, Jatinder Dhaliwal, Kanwaljit Chopr. 7, 8-dihydroxyflavone Ameliorates Cholinergic Dysfunction, Inflammation, Oxidative Stress, and Apoptosis in a Rat Model of Vascular Dementia. Neurochemical research. 2024-02-01. PMID:38300457. |
p-akt, p-creb, bdnf, and neurotransmitter (nt) (glu, gaba, and ach) levels were also analyzed in the hippocampus of 2-vo rats. our results show that 7,8-dhf effectively improved memory performance and cholinergic dysfunction in 2-vo model rats. |
2024-02-01 |
2024-02-03 |
rat |
| Giulio Rosano, Allan Barzasi, Timothy Lynag. Loss of activation by GABA in vertebrate delta ionotropic glutamate receptors. Proceedings of the National Academy of Sciences of the United States of America. vol 121. issue 6. 2024-01-29. PMID:38285949. |
surprisingly, we observe that many iglurs of the delta family are activated by the classical inhibitory neurotransmitter, γ-aminobutyric acid (gaba). |
2024-01-29 |
2024-02-01 |
Not clear |
| Lisa Hahn, Simon B Eickhoff, Karsten Mueller, Leonhard Schilbach, Henryk Barthel, Klaus Fassbender, Klaus Fliessbach, Johannes Kornhuber, Johannes Prudlo, Matthis Synofzik, Jens Wiltfang, Janine Diehl-Schmid, Markus Otto, Juergen Dukart, Matthias L Schroete. Resting-state alterations in behavioral variant frontotemporal dementia are related to the distribution of monoamine and GABA neurotransmitter systems. eLife. vol 13. 2024-01-15. PMID:38224473. |
resting-state alterations in behavioral variant frontotemporal dementia are related to the distribution of monoamine and gaba neurotransmitter systems. |
2024-01-15 |
2024-01-17 |
Not clear |
| Xi Zhang, Hong Zheng, Zhitao Ni, Yuyin Shen, Die Wang, Wenqing Li, Liangcai Zhao, Chen Li, Hongchang Ga. Fibroblast growth factor 21 alleviates diabetes-induced cognitive decline. Cerebral cortex (New York, N.Y. : 1991). 2024-01-14. PMID:38220573. |
metabolomics results revealed that fgf21 modulated dicd metabolic alterations related to glucose and neurotransmitter metabolism, which are characterized by distinct recovered enrichment of [3-13c]-lactate, [3-13c]-aspartate, [4-13c]-glutamine, [3-13c]-glutamine, [4-13c]-glutamate, and [4-13c]- γ-aminobutyric acid (gaba) from [1-13c]-glucose. |
2024-01-14 |
2024-01-17 |
mouse |
| Mridula Bhalla, C Justin Le. Long-term inhibition of ODC1 in APP/PS1 mice rescues amyloid pathology and switches astrocytes from a reactive to active state. Molecular brain. vol 17. issue 1. 2024-01-12. PMID:38216963. |
alzheimer's disease (ad) is characterized by the loss of memory due to aggregation of misphosphorylated tau and amyloid beta (aβ) plaques in the brain, elevated release of inhibitory neurotransmitter gamma-aminobutyric acid (gaba) and reactive oxygen species from astrocytes, and subsequent neurodegeneration. |
2024-01-12 |
2024-01-15 |
mouse |
| Timur Liwinski, Undine E Lang, Annette B Brühl, Else Schneide. Exploring the Therapeutic Potential of Gamma-Aminobutyric Acid in Stress and Depressive Disorders through the Gut-Brain Axis. Biomedicines. vol 11. issue 12. 2023-12-23. PMID:38137351. |
research conducted on individuals with depression reveals that major depressive disorders (mdds) coincide with diminished levels of the inhibitory neurotransmitter γ-aminobutyric acid (gaba) in the brain, as well as modifications in the subunit composition of the primary receptors (gaba |
2023-12-23 |
2023-12-25 |
Not clear |
| Haijun Bao, Zuojie Peng, Xukai Cheng, Chenxing Jian, Xianguo Li, Yongping Shi, Wenzhong Zhu, Yuan Hu, Mi Jiang, Jia Song, Feifei Fang, Jinhuang Chen, Xiaogang Sh. GABA induced by sleep deprivation promotes the proliferation and migration of colon tumors through miR-223-3p endogenous pathway and exosome pathway. Journal of experimental & clinical cancer research : CR. vol 42. issue 1. 2023-12-19. PMID:38105184. |
this study explored the specific mechanism through which sleep deprivation promotes the proliferation and migration of colon cancer, with a focus on the neurotransmitter gaba. |
2023-12-19 |
2023-12-21 |
Not clear |
| Oliver D Howes, Bernard R Bukala, Katherine Bec. Schizophrenia: from neurochemistry to circuits, symptoms and treatments. Nature reviews. Neurology. 2023-12-19. PMID:38110704. |
this evidence demonstrates regionally specific neurotransmitter alterations, including higher glutamate and dopamine measures in the basal ganglia, and lower glutamate, dopamine and γ-aminobutyric acid (gaba) levels in cortical regions, particularly the frontal cortex, relative to healthy individuals. |
2023-12-19 |
2023-12-21 |
Not clear |
| Xiaomu Qiao, Tianhao Zhou, Jing Zhang, Lixin Zhang, Yaobin Lu, Jia Huan. Functional validation of A2'N mutation of the RDL GABA receptor against fipronil via molecular modeling and genome engineering in Drosophila. Pest management science. 2023-12-12. PMID:38086568. |
insect rdl (resistant to dieldrin) receptors are essential pentameric ligand-gated chloride channels that mediate the neuroinhibitory effect of gaba, the chief inhibitory neurotransmitter in the central nervous system. |
2023-12-12 |
2023-12-17 |
drosophila_melanogaster |
| Laura Kubens, Ann-Kathrin Weishaupt, Vivien Michaelis, Isabelle Rohn, Fabian Mohr, Julia Bornhors. Exposure to the environmentally relevant fungicide Maneb: Studying toxicity in the soil nematode Caenorhabditis elegans. Environment international. vol 183. 2023-12-10. PMID:38071851. |
nevertheless, an alteration in the neurotransmitter homeostasis of dopamine, acetylcholine, and gamma-butyric acid (gaba) was observed as well as morphological changes in the dopaminergic neurons upon maneb exposure, which underlines the assumption of the neurotoxic potential of maneb. |
2023-12-10 |
2023-12-17 |
caenorhabditis_elegans |
| Deepika Shukla, Anshika Goel, Pravat K Mandal, Shallu Joon, Khushboo Punjabi, Yashika Arora, Rajnish Kumar, Veer Singh Mehta, Padam Singh, Joseph C Maroon, Rishu Bansal, Kanika Sandal, Rimil Guha Roy, Avantika Samkaria, Shallu Sharma, Sandhya Sandhilya, Shradha Gaur, S Parvathi, Mallika Josh. Glutathione Depletion and Concomitant Elevation of Susceptibility in Patients with Parkinson's Disease: State-of-the-Art MR Spectroscopy and Neuropsychological Study. ACS chemical neuroscience. 2023-12-05. PMID:38050970. |
in the current study, we have investigated the impact of os in pd by measuring the antioxidant glutathione (gsh) levels from the substantia nigra (sn), left hippocampus (lh) and neurotransmitter γ-amino butyric acid (gaba) levels from sn region. |
2023-12-05 |
2023-12-10 |
Not clear |
| Jianshe Zhou, Shuaijie Sun, Ruiting Li, Huifeng Xu, Ming Li, Zhichao L. Transcriptome analysis of Schizothorax oconnori (Cypriniformes: Cyprinidae) oocytes: The role of K Fish physiology and biochemistry. 2023-12-04. PMID:38047980. |
neurotransmitter (ach, npy, and gaba) and peptide hormone (gnrh3) binding to g protein-coupled receptors (gpcrs) frees g-protein βγ subunits to interact with the g protein-gated inward rectifier k |
2023-12-04 |
2023-12-10 |
Not clear |
| Nina-Francesca Parrella, Aron T Hill, Lillian M Dipnall, Yuk Jing Loke, Peter G Enticott, Talitha C For. Inhibitory dysfunction and social processing difficulties in autism: A comprehensive narrative review. Journal of psychiatric research. vol 169. 2023-11-28. PMID:38016393. |
the primary inhibitory neurotransmitter γ-aminobutyric acid (gaba) has a prominent role in regulating neural development and function, with disruption to gabaergic signalling linked to behavioural phenotypes associated with neurodevelopmental disorders, particularly autism. |
2023-11-28 |
2023-12-07 |
Not clear |
| Ariel M Lyons-Warren, Evelyne K Tantry, Elizabeth H Moss, Mikhail Y Kochukov, Benjamin D W Belfort, Joshua Ortiz-Guzman, Zachary Freyberg, Benjamin R Arenkie. Co-transmitting interneurons in the mouse olfactory bulb regulate olfactory detection and discrimination. Cell reports. vol 42. issue 12. 2023-11-19. PMID:37980561. |
here, we implement intersectional genetics in mice to selectively block gaba or dopamine release from superficial short-axon cells to identify their distinct cellular targets, impact on circuit function, and behavioral contribution of each neurotransmitter toward olfactory behaviors. |
2023-11-19 |
2023-11-29 |
mouse |