Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Matthew S Milak, Rain Rashid, Zhengchao Dong, Lawrence S Kegeles, Michael F Grunebaum, R Todd Ogden, Xuejing Lin, Stephanie T Mulhern, Raymond F Suckow, Thomas B Cooper, John G Keilp, Xiangling Mao, Dikoma C Shungu, J John Man. Assessment of Relationship of Ketamine Dose With Magnetic Resonance Spectroscopy of Glx and GABA Responses in Adults With Major Depression: A Randomized Clinical Trial. JAMA network open. vol 3. issue 8. 2021-01-04. PMID:32785636. |
assessment of relationship of ketamine dose with magnetic resonance spectroscopy of glx and gaba responses in adults with major depression: a randomized clinical trial. |
2021-01-04 |
2023-08-13 |
Not clear |
Sz-Jie Wu, Chia-Yu Chang, Yen-Ting Lai, Yuan-Tay Shy. Increasing γ-Aminobutyric Acid Content in Vegetable Soybeans via High-Pressure Processing and Efficacy of Their Antidepressant-Like Activity in Mice. Foods (Basel, Switzerland). vol 9. issue 11. 2020-12-01. PMID:33207592. |
this study applied high-pressure processing (hpp) technology to enrich the gamma aminobutyric acid (gaba) content in vegetable soybeans and evaluated its antidepressant efficacy on mice, with depression induced by the unpredictable chronic mild stress (ucms) model. |
2020-12-01 |
2023-08-13 |
mouse |
Arthur D P Mak, Yuen Man Ho, Owen N W Leung, Idy Wing Yi Chou, Rashid Lui, Sunny Wong, David K W Yeung, Winnie C W Chu, Richard Edden, Sandra Chan, Linda Lam, Justin W. Unaltered Brain GABA Concentrations and Resting fMRI Activity in Functional Dyspepsia With and Without Comorbid Depression. Frontiers in psychiatry. vol 11. 2020-10-22. PMID:33061916. |
unaltered brain gaba concentrations and resting fmri activity in functional dyspepsia with and without comorbid depression. |
2020-10-22 |
2023-08-13 |
Not clear |
Kyle J Brymer, Erin Y Fenton, Lisa E Kalynchuk, Hector J Carunch. Peripheral Etanercept Administration Normalizes Behavior, Hippocampal Neurogenesis, and Hippocampal Reelin and GABA Frontiers in pharmacology. vol 9. 2020-10-01. PMID:29515447. |
peripheral etanercept administration normalizes behavior, hippocampal neurogenesis, and hippocampal reelin and gaba depression is a serious psychiatric disorder frequently comorbid with autoimmune disorders. |
2020-10-01 |
2023-08-13 |
rat |
Lei Liu, Wataru Ito, Alexei Morozo. Overexpression of channelrhodopsin-2 interferes with the GABAb receptor-mediated depression of GABA release from the somatostatin-containing interneurons of the prefrontal cortex. Neurophotonics. vol 5. issue 2. 2020-10-01. PMID:29531964. |
overexpression of channelrhodopsin-2 interferes with the gabab receptor-mediated depression of gaba release from the somatostatin-containing interneurons of the prefrontal cortex. |
2020-10-01 |
2023-08-13 |
Not clear |
Dan Wang, Xuan Wang, Meng-Ting Luo, Hui Wang, Yue-Hua L. Gamma-Aminobutyric Acid Levels in the Anterior Cingulate Cortex of Perimenopausal Women With Depression: A Magnetic Resonance Spectroscopy Study. Frontiers in neuroscience. vol 13. 2020-10-01. PMID:31481863. |
gamma-aminobutyric acid levels in the anterior cingulate cortex of perimenopausal women with depression: a magnetic resonance spectroscopy study. |
2020-10-01 |
2023-08-13 |
Not clear |
Dan Wang, Xuan Wang, Meng-Ting Luo, Hui Wang, Yue-Hua L. Gamma-Aminobutyric Acid Levels in the Anterior Cingulate Cortex of Perimenopausal Women With Depression: A Magnetic Resonance Spectroscopy Study. Frontiers in neuroscience. vol 13. 2020-10-01. PMID:31481863. |
we aimed to determine the changes in gaba levels in the acc of perimenopausal women with depression. |
2020-10-01 |
2023-08-13 |
Not clear |
Yuan Li, Xin Zhang, Lixin Chen, Bo Yang, Rubo Su. Cerebellar fastigial nucleus is involved in post-stroke depression through direct cerebellar-hypothalamic GABAergic and glutamatergic projections. Experimental and therapeutic medicine. vol 18. issue 4. 2020-10-01. PMID:31555378. |
the present study aimed to investigate whether the cerebellar fastigial nucleus (fn) is involved in post-stroke depression (psd), and to observe the effect of direct cerebellar-hypothalamic γ-aminobutyric acid (gaba)ergic and glutamatergic projections on psd, in order to understand the mechanisms underlying the cerebellar modulation of mood and emotion. |
2020-10-01 |
2023-08-13 |
rat |
Beza A Dagne, Melis K Sunay, Noëlie S Cayla, Yi-Bing Ouyang, Susan J Knox, Rona G Giffard, John R Adler, Bruce Macive. High Dose Gamma Radiation Selectively Reduces GABAA-slow Inhibition. Cureus. vol 9. issue 3. 2020-09-30. PMID:28401026. |
however, exposure to 60 gy of irradiation resulted in a small, but statistically significant (14% change; anova p < 0.005; n = 9) reduction in synaptic inhibition seen at 100 ms, indicating a selective depression of the gamma-aminobutyric acid (gaba |
2020-09-30 |
2023-08-13 |
rat |
Serena Boccella, Monica Iannotta, Claudia Cristiano, Fabio Arturo Iannotti, Fabio Del Bello, Francesca Guida, Carmela Belardo, Rosmara Infantino, Flavia Ricciardi, Mario Giannella, Antonio Calignano, Vincenzo Di Marzo, Sabatino Maione, Livio Luong. Treatment With 2-Pentadecyl-2-Oxazoline Restores Mild Traumatic Brain Injury-Induced Sensorial and Neuropsychiatric Dysfunctions. Frontiers in pharmacology. vol 11. 2020-09-28. PMID:32161542. |
depression), ii) selectively normalize cortical gaba levels, iii) rescue the impaired neuronal activity in the prefrontal cortex. |
2020-09-28 |
2023-08-13 |
mouse |
Yu Zhang, Chengxi Liu, Lin Zhang, Wenjing Zhou, Shouyang Yu, Rulan Yi, Dan Luo, Xiaoyun F. Effects of Propofol on Electrical Synaptic Strength in Coupling Reticular Thalamic GABAergic Parvalbumin-Expressing Neurons. Frontiers in neuroscience. vol 14. 2020-09-28. PMID:32410945. |
notably, the propofol-induced depression of electrical synaptic strength between trn pv+ neurons was diminished by saclofen (10 μm, antagonist of gaba |
2020-09-28 |
2023-08-13 |
Not clear |
Ke Ma, Hongxiu Zhang, Shiyuan Wang, Huaxin Wang, Yuan Wang, Juhai Liu, Xiaobin Song, Zhenfei Dong, Xiaochun Han, Yanan Zhang, Honglei Li, Abdul Rahaman, Shijun Wang, Zulqarnain Baloc. The molecular mechanism underlying GABAergic dysfunction in nucleus accumbens of depression-like behaviours in mice. Journal of cellular and molecular medicine. vol 23. issue 10. 2020-09-02. PMID:31430030. |
chronic stress causes the impaired gaba synthesis, release and uptake by up-regulating mirnas and down-regulating mrnas and proteins, which may reveal the molecular mechanisms for the decreased gaba concentrations in the nac tissue of cums-induced depression. |
2020-09-02 |
2023-08-13 |
mouse |
Caifeng Shao, Pei Chen, Qian Chen, Mingwei Zhao, Wei-Ning Zhang, Kun Yan. Mu opioid receptors inhibit GABA release from parvalbumin interneuron terminals onto CA1 pyramidal cells. Biochemical and biophysical research communications. vol 522. issue 4. 2020-08-31. PMID:31818459. |
on the other hand, conventional electric shock, presumably activating non-selectively presynaptic gabaergic terminals, also induced gaba release; however, this release showed relatively limited depression by mors activation. |
2020-08-31 |
2023-08-13 |
Not clear |
J W Liao, S S Wang, H H Yang, P Ma, C R Li, J Y Pa. [Comparative analysis of serum glutamate and gamma-aminobutyric acid levels in patients with bipolar depressive disorder and major depression disorder]. Zhonghua yi xue za zhi. vol 100. issue 23. 2020-08-10. PMID:32536126. |
[comparative analysis of serum glutamate and gamma-aminobutyric acid levels in patients with bipolar depressive disorder and major depression disorder]. |
2020-08-10 |
2023-08-13 |
Not clear |
Matthew J Girgenti, Eric S Wohleb, Sameet Mehta, Sriparna Ghosal, Manoela V Fogaca, Ronald S Duma. Prefrontal cortex interneurons display dynamic sex-specific stress-induced transcriptomes. Translational psychiatry. vol 9. issue 1. 2020-08-05. PMID:31712551. |
abnormalities of gaba interneurons, particularly the somatostatin (human, sst; mouse, sst) subtype, have been reported in postmortem brains of depressed subjects and include sex differences that could explain the increased incidence of depression in women. |
2020-08-05 |
2023-08-13 |
mouse |
Ariela Frieder, Madeleine Fersh, Rachel Hainline, Kristina M Deligiannidi. Pharmacotherapy of Postpartum Depression: Current Approaches and Novel Drug Development. CNS drugs. vol 33. issue 3. 2020-07-02. PMID:30790145. |
evidence supporting the role of neuroactive steroids and γ-aminobutyric acid (gaba) in the pathophysiology of postpartum depression led to the investigation of synthetic neuroactive steroids and their analogs as potential treatment for postpartum depression. |
2020-07-02 |
2023-08-13 |
Not clear |
Jennifer G. Levitt, Guldamla Kalender, Joseph O’Neill, Joel P. Diaz, Ian A. Cook, Nathaniel Ginder, David Krantz, Michael J. Minzenberg, Nikita Vince-Cruz, Lydia D. Nguyen, Jeffry R. Alger, Andrew F. Leuchte. Dorsolateral prefrontal γ-aminobutyric acid in patients with treatment-resistant depression after transcranial magnetic stimulation measured with magnetic resonance spectroscopy Journal of psychiatry & neuroscience : JPN. vol 44. issue 6. 2020-06-22. PMID:31199104. |
dorsolateral prefrontal γ-aminobutyric acid in patients with treatment-resistant depression after transcranial magnetic stimulation measured with magnetic resonance spectroscopy the therapeutic mechanism of repetitive transcranial magnetic stimulation (rtms) for treatment-resistant depression (trd) may involve modulation of γ-aminobutyric acid (gaba) levels. |
2020-06-22 |
2023-08-13 |
Not clear |
Ahmed Nagu. Brexanolone and postpartum depression: what does it have to do with GABA? Archives of women's mental health. vol 22. issue 6. 2020-05-19. PMID:31302763. |
brexanolone and postpartum depression: what does it have to do with gaba? |
2020-05-19 |
2023-08-13 |
Not clear |
Timothy S Pulverenti, Gabriel S Trajano, Benjamin J C Kirk, Anthony J Blazevic. The loss of muscle force production after muscle stretching is not accompanied by altered corticospinal excitability. European journal of applied physiology. vol 119. issue 10. 2020-02-06. PMID:31456049. |
the aim of the present study was to determine whether depression of maximal muscular force and neural drive subsequent to prolonged ( ≥ 60 s) passive muscle stretching is associated with altered corticospinal excitability or intracortical (gaba |
2020-02-06 |
2023-08-13 |
Not clear |
Ya-Ping Chen, Chuang Wang, Jiang-Ping X. Chronic unpredictable mild stress induced depression-like behaviours and glutamate-glutamine cycling dysfunctions in both blood and brain of mice. Pharmaceutical biology. vol 57. issue 1. 2019-12-30. PMID:30990732. |
recently, depression has been observed in association with metabolic abnormalities of the glutamate (glu)-glutamine (gln) cycling, which is regulated by glu, gln and γ-aminobutyric acid (gaba) amino acids. |
2019-12-30 |
2023-08-13 |
mouse |