| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Haohui Sun, Yue Hao, Hao Liu, Feng Ga. The immunomodulatory effects of GLP-1 receptor agonists in neurogenerative diseases and ischemic stroke treatment. Frontiers in immunology. vol 16. 2025-03-26. PMID:40134421. |
this review presented fundamental information regarding two categories of glp-1 receptor agonists (glp-1ras): peptide-based and small molecule compounds, and elaborated their potential neuroprotective effects by inhibiting neuroinflammation, reducing neuronal apoptosis, and ultimately improving cognitive function in various neurodegenerative diseases. |
2025-03-26 |
2025-03-28 |
Not clear |
| Şeyma Aydın, Selçuk Özdemir, Ahmet Adıgüze. The Potential of cfDNA as Biomarker: Opportunities and Challenges for Neurodegenerative Diseases. Journal of molecular neuroscience : MN. vol 75. issue 1. 2025-03-13. PMID:40080233. |
cell-free dna (cfdna), including fragmented dna released into bodily fluids via apoptosis, necrosis, or active secretion, has emerged as a promising non-invasive diagnostic tool for various disorders including neurodegenerative diseases. |
2025-03-13 |
2025-03-16 |
Not clear |
| Shi Huang, Yaxin Lu, Wanzhen Fang, Yanjiao Huang, Qiang Li, Zhiliang X. Neurodegenerative diseases and neuroinflammation-induced apoptosis. Open life sciences. vol 20. issue 1. 2025-03-04. PMID:40026360. |
neurodegenerative diseases and neuroinflammation-induced apoptosis. |
2025-03-04 |
2025-03-06 |
Not clear |
| Shi Huang, Yaxin Lu, Wanzhen Fang, Yanjiao Huang, Qiang Li, Zhiliang X. Neurodegenerative diseases and neuroinflammation-induced apoptosis. Open life sciences. vol 20. issue 1. 2025-03-04. PMID:40026360. |
this article presents a summary of recent studies on the relationship between neuronal apoptosis caused by excessive neuroinflammation and neurodegenerative diseases. |
2025-03-04 |
2025-03-06 |
Not clear |
| Fatma Gonca Kocanc. Effect of Pimecrolimus on apoptotic pathways in H Toxicology research. vol 14. issue 1. 2025-02-19. PMID:39968517. |
effect of pimecrolimus on apoptotic pathways in h neurodegenerative diseases (nds), including alzheimer's and parkinson's, are marked by progressive neuronal loss, driven largely by oxidative stress and apoptosis. |
2025-02-19 |
2025-02-23 |
Not clear |
| Dongyi Liao, Yujie Zhang, Shuangyang Li, Hongmei Tang, Xue Ba. miRNAs in neurodegenerative diseases: from target screening to precision therapy. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. 2025-02-19. PMID:39969752. |
mirnas are critical for different disease development processes, including cell growth, signaling, apoptosis, cancer and neurodegenerative diseases. |
2025-02-19 |
2025-02-23 |
Not clear |
| Xiaotong Wang, Liang Sun, Xudong Han, Zhanglong Li, Yuqing Xing, Xinyue Chen, Ruofan Xi, Yuecong Sun, Guilong Wang, Ping Zha. The molecular mechanisms underlying retinal ganglion cell apoptosis and optic nerve regeneration in glaucoma (Review). International journal of molecular medicine. vol 55. issue 4. 2025-02-14. PMID:39950327. |
glaucoma is a neurodegenerative disease characterized by progressive and irreversible necrosis and apoptosis of retinal ganglion cells (rgcs). |
2025-02-14 |
2025-02-16 |
Not clear |
| Manoj Soni, Awadhesh Kumar, Rakesh Kumar, Mehak Dangi, Ajit Kumar, Vijay Kuma. Focusing on Keap1, IKKβ, and Bcl2 proteins: predicted targets of stigmasterol in neurodegeneration. Journal of receptor and signal transduction research. 2025-02-13. PMID:39947740. |
oxidative stress, driven by excess ros, damages lipids, proteins, and dna, leading to neuronal apoptosis and inflammation, a key factor in neurodegenerative diseases. |
2025-02-13 |
2025-02-16 |
Not clear |
| Yuemin Qiu, Lin Cheng, Yinyi Xiong, Ziying Liu, Chunxiao Shen, Liangliang Wang, Yujia Lu, Shufei Wei, Lushun Zhang, Seung Bum Yang, Xiaorong Zhan. Advances in the Study of Necroptosis in Vascular Dementia: Focus on Blood-Brain Barrier and Neuroinflammation. CNS neuroscience & therapeutics. vol 31. issue 2. 2025-02-07. PMID:39915907. |
necroptosis, also known asprogrammed necrosis, is a mode of programmed cell death distinct from apoptosis and is closely associated with ischemic injury and neurodegenerative diseases. |
2025-02-07 |
2025-02-09 |
Not clear |
| Arshdeep Kaur, Rohit, Khadga Raj Ara. Unraveling the dual role of bilirubin in neurological Diseases: A Comprehensive exploration of its neuroprotective and neurotoxic effects. Brain research. 2025-01-26. PMID:39864645. |
the aim of this article is to explore the dual role of bilirubin as neuroprotective and neurotoxic, essential for establishing effective therapeutic outcomes for neurodegenerative diseases by looking at its cellular mechanisms and discussing how bilirubin's antioxidant properties can shield neurons and, in some situations, may induce oxidative stress and apoptosis. |
2025-01-26 |
2025-01-29 |
Not clear |
| b' Nuray \\xc3\\x9cremi\\xc5\\x9f, Muhammed Mehdi \\xc3\\x9cremi\\xc5\\x9. Oxidative/Nitrosative Stress, Apoptosis, and Redox Signaling: Key Players in Neurodegenerative Diseases. Journal of biochemical and molecular toxicology. vol 39. issue 1. 2025-01-12. PMID:39799559.' |
oxidative/nitrosative stress, apoptosis, and redox signaling: key players in neurodegenerative diseases. |
2025-01-12 |
2025-01-16 |
human |
| b' Nuray \\xc3\\x9cremi\\xc5\\x9f, Muhammed Mehdi \\xc3\\x9cremi\\xc5\\x9. Oxidative/Nitrosative Stress, Apoptosis, and Redox Signaling: Key Players in Neurodegenerative Diseases. Journal of biochemical and molecular toxicology. vol 39. issue 1. 2025-01-12. PMID:39799559.' |
this process results in the induction of apoptosis, which is important in the pathogenesis of neurodegenerative diseases through oxidative stress. |
2025-01-12 |
2025-01-16 |
human |
| Jingjing Lin, Junyi Wu, Yifan Xu, Yeli Zhao, Shasha Y. RhFGF21 protected PC12 cells against mitochondrial apoptosis triggered by H Experimental cell research. vol 445. issue 1. 2025-01-11. PMID:39793749. |
rhfgf21 protected pc12 cells against mitochondrial apoptosis triggered by h one of the pathological mechanisms of neurodegenerative diseases is that oxidative stress damages neurons. |
2025-01-11 |
2025-01-14 |
Not clear |
| Alícia de Sousa Moreira, Bruna Lopes, Ana Catarina Sousa, André Coelho, Patrícia Sousa, Ana Araújo, Esmeralda Delgado, Rui Alvites, Ana Colette Mauríci. Stem Cell-Based Therapies for Glaucoma Treatment: A Review Bridging the Gap in Veterinary Patients. International journal of molecular sciences. vol 26. issue 1. 2025-01-11. PMID:39796087. |
among these, glaucoma stands out as a multifactorial neurodegenerative disease involving elevated intraocular pressure, retinal ganglion cell apoptosis, and optic nerve damage, ultimately resulting in blindness in both humans and dogs. |
2025-01-11 |
2025-01-14 |
human |
| Fangxin Guo, Xudi Qin, Jian Mao, Yan Xu, Jianping Xi. Potential Protective Effects of Pungent Flavor Components in Neurodegenerative Diseases. Molecules (Basel, Switzerland). vol 29. issue 23. 2024-12-17. PMID:39683859. |
studies have shown that some plant extracts with pungent flavor components have a certain neuroprotective effect in neurodegenerative diseases, and their mechanisms mainly involve inhibiting neuronal apoptosis, promoting neuronal regeneration, reducing mitochondrial degeneration, and reducing the production of oxides such as reactive oxygen species in cells, which are of great significance for exploring the treatment of neurodegenerative diseases. |
2024-12-17 |
2024-12-21 |
Not clear |
| Naina Gaikwad, Rucha Sarwade, Sourav Halder, Gaurav Agarwal, Vasudevan Seshadr. HuD regulates apoptosis in N2a cells by regulating Msi2 expression. PloS one. vol 19. issue 12. 2024-12-16. PMID:39680531. |
apoptosis is one of the underlying causes of neurodegenerative diseases like alzheimer's disease. |
2024-12-16 |
2024-12-21 |
mouse |
| Seul-Ki Kim, Yong-Jin Kwon, Eun-Bi Seo, Hyun-Seung Lee, Jie Ohn Sohn, Hyun Mu Shin, Sung Joon Kim, Sang-Kyu Y. Neuroprotective Effects of STAT3 Inhibitor on Hydrogen Peroxide-Induced Neuronal Cell Death via the ERK/CREB Signaling Pathway. Neurochemical research. vol 50. issue 1. 2024-12-08. PMID:39648181. |
this study investigates the neuroprotective potential of stat3 inhibition in reducing oxidative stress-induced neuronal damage and apoptosis, a major factor contributing to the onset and progression of neurodegenerative diseases, including alzheimer's disease (ad). |
2024-12-08 |
2024-12-11 |
Not clear |
| Jiahui Lv, Xinmiao Zhao, Linjie Zhao, Chengjun Gong, Wanjie Zheng, Li Guo, Jun Wang, Tingming Lian. The Notable Role of Telomere Length Maintenance in Complex Diseases. Biomedicines. vol 12. issue 11. 2024-11-27. PMID:39595175. |
in addition, the association between telomeres and neurodegenerative diseases is discussed, detailing how telomere attrition heightens disease risk and outlining multiple pathways by which telomerase protects neurons from damage and apoptosis. |
2024-11-27 |
2024-11-29 |
Not clear |
| Ruiying Yuan, Dan Gao, Guibing Yang, Dongzhi Zhuoma, Zhen Pu, Yangzhen Ciren, Bin Li, Jianqing Y. Oxysophocarpine Prevents the Glutamate-Induced Apoptosis of HT-22 Cells via the Nrf2/HO-1 Signaling Pathway. Current issues in molecular biology. vol 46. issue 11. 2024-11-26. PMID:39590371. |
these results suggest that osc can exert neuroprotective effects by regulating the nrf2/ho-1 pathway to inhibit neuronal cell apoptosis, potentially aiding in the treatment of neurodegenerative diseases. |
2024-11-26 |
2024-11-29 |
Not clear |
| Luodan A, Linghui Qu, Juncai He, Lingling Ge, Hui Gao, Xiaona Huang, Tianjing You, Hong Gong, Qingle Liang, Siyu Chen, Jing Xie, Haiwei X. Exosomes derived from IFNγ-stimulated mesenchymal stem cells protect photoreceptors in RCS rats by restoring immune homeostasis through tsRNAs. Cell communication and signaling : CCS. vol 22. issue 1. 2024-11-14. PMID:39538308. |
retinitis pigmentosa is a neurodegenerative disease with major pathologies of photoreceptor apoptosis and immune imbalance. |
2024-11-14 |
2024-11-17 |
rat |