| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Peter E Mouser, Elizabeth Head, Kwang-Ho Ha, Troy T Roh. Caspase-mediated cleavage of glial fibrillary acidic protein within degenerating astrocytes of the Alzheimer's disease brain. The American journal of pathology. vol 168. issue 3. 2006-04-19. PMID:16507909. |
in vitro characterization of this antibody using both a cell-free system and a cell model system of apoptosis demonstrated that the antibody (termed gfap caspase-cleavage product antibody or gfap-ccp ab) immunolabeled the predicted caspase-cleavage fragment, but not full-length gfap, by western blot analysis. |
2006-04-19 |
2023-08-12 |
Not clear |
| Kathrin D Geiger, Peter Stoldt, Wolfgang Schlote, Amin Derouich. Ezrin immunoreactivity reveals specific astrocyte activation in cerebral HIV. Journal of neuropathology and experimental neurology. vol 65. issue 1. 2006-03-14. PMID:16410752. |
normal ezrin-ir, when paralleled by upregulated gfap, reflects astroglial activation not associated with neuronal apoptosis. |
2006-03-14 |
2023-08-12 |
human |
| Ravinder Pannu, Ernest Barbosa, Avtar K Singh, Inderjit Sing. Attenuation of acute inflammatory response by atorvastatin after spinal cord injury in rats. Journal of neuroscience research. vol 79. issue 3. 2005-06-10. PMID:15605375. |
in addition, neuronal apoptosis was detected 24 hr after injury followed by a profound increase in ed1-positive inflammatory infiltrates, glial fibrillary acidic protein (gfap)-positive reactive astrocytes, and oligodendrocyte apoptosis by 1 week after sci relative to control. |
2005-06-10 |
2023-08-12 |
rat |
| S Mijatovic, D Maksimovic-Ivanic, J Radovic, Dj Miljkovic, Lj Harhaji, O Vuckovic, S Stosic-Grujicic, M Mostarica Stojkovic, V Trajkovi. Anti-glioma action of aloe emodin: the role of ERK inhibition. Cellular and molecular life sciences : CMLS. vol 62. issue 5. 2005-04-15. PMID:15747063. |
a selective inhibitor of erk activation, pd98059, mimicked the effects of ae on glioma cell morphology and gfap expression, but failed to induce either apoptosis or autophagy. |
2005-04-15 |
2023-08-12 |
rat |
| Josef Zamecnik, Matija Snuderl, Tomas Eckschlager, Marketa Chanova, Marie Hladikova, Michal Tichy, Roman Kode. Pediatric intracranial ependymomas: prognostic relevance of histological, immunohistochemical, and flow cytometric factors. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. vol 16. issue 10. 2004-05-25. PMID:14559980. |
immunoexpression of a broad spectrum of antigens was evaluated, including mib-1, topoisomerase-iialpha, cyclin d1, glial and epithelial proteins (gfap, ema, cytokeratins), molecules involved in controlling apoptosis (bcl-2, caspase-3/cpp32), and p53 oncoprotein. |
2004-05-25 |
2023-08-12 |
Not clear |
| Toshiko Sawaguchi, Franco Patricia, Hazim Kadhim, Jose Groswasser, Martine Sottiaux, Hiroshi Nishida, Andre Kah. Clinicopathological correlation between brainstem gliosis using GFAP as a marker and sleep apnea in the sudden infant death syndrome. Early human development. vol 75 Suppl. 2004-04-21. PMID:14693386. |
gliosis detected by immunohistochemistry of glial fibrillary acidic protein (gfap) is a marker of apoptosis. |
2004-04-21 |
2023-08-12 |
Not clear |
| M H Chen, W K Yang, J Whang-Peng, L S Lee, T S Huan. Differential inducibilities of GFAP expression, cytostasis and apoptosis in primary cultures of human astrocytic tumours. Apoptosis : an international journal on programmed cell death. vol 3. issue 3. 2003-12-23. PMID:14646498. |
differential inducibilities of gfap expression, cytostasis and apoptosis in primary cultures of human astrocytic tumours. |
2003-12-23 |
2023-08-12 |
human |
| S de Bernardo, S Canals, M J Casarejos, E Rodriguez-Martin, M A Men. Glia-conditioned medium induces de novo synthesis of tyrosine hydroxylase and increases dopamine cell survival by differential signaling pathways. Journal of neuroscience research. vol 73. issue 6. 2003-10-14. PMID:12949908. |
the data presented herein show that tyrosine kinase receptors, camp-dependent protein kinase, pi-3k, and mapk signaling pathways are implicated in de novo synthesis of th+ cells induced by gcm as well as in da cell apoptosis and that these effects are unrelated to increased gfap expression. |
2003-10-14 |
2023-08-12 |
Not clear |
| Veronica Asnaghi, Chiara Gerhardinger, Todd Hoehn, Abidemi Adeboje, Mara Lorenz. A role for the polyol pathway in the early neuroretinal apoptosis and glial changes induced by diabetes in the rat. Diabetes. vol 52. issue 2. 2003-04-07. PMID:12540628. |
we tested the hypothesis that the apoptosis of inner retina neurons and increased expression of glial fibrillary acidic protein (gfap) observed in the rat after a short duration of diabetes are mediated by polyol pathway activity. |
2003-04-07 |
2023-08-12 |
mouse |
| Veronica Asnaghi, Chiara Gerhardinger, Todd Hoehn, Abidemi Adeboje, Mara Lorenz. A role for the polyol pathway in the early neuroretinal apoptosis and glial changes induced by diabetes in the rat. Diabetes. vol 52. issue 2. 2003-04-07. PMID:12540628. |
diabetic mice, known to have much lower aldose reductase activity in other tissues when compared with rats, did not accumulate sorbitol and fructose in the retina and were protected from neuronal apoptosis and gfap changes in the presence of ghb levels of 14 +/- 2%. |
2003-04-07 |
2023-08-12 |
mouse |
| G D Kommers, D J King, B S Seal, K P Carmichael, C C Brow. Pathogenesis of six pigeon-origin isolates of Newcastle disease virus for domestic chickens. Veterinary pathology. vol 39. issue 3. 2002-11-22. PMID:12014499. |
numerous reactive astrocytes were observed in brain sections stained for gfap among all the isolates, the ihc-casp demonstrated that apoptosis was very prominent in the ellipsoid-associated cells of the spleen at 2 dpi. |
2002-11-22 |
2023-08-12 |
pigeon |
| K Lieuallen, L A Pennacchio, M Park, R M Myers, G G Lenno. Cystatin B-deficient mice have increased expression of apoptosis and glial activation genes. Human molecular genetics. vol 10. issue 18. 2001-12-04. PMID:11555622. |
these genes are cathepsin s, c1q b-chain of complement (c1qb), beta2-microglobulin, glial fibrillary acidic protein (gfap), apolipoprotein d, fibronectin 1 and metallothionein ii, which are expected to be involved in increased proteolysis, apoptosis and glial activation. |
2001-12-04 |
2023-08-12 |
mouse |
| S Fredduzzi, G Mariucci, M Tantucci, P Del Soldato, M V Ambrosin. Nitro-aspirin (NCX4016) reduces brain damage induced by focal cerebral ischemia in the rat. Neuroscience letters. vol 302. issue 2-3. 2001-07-12. PMID:11290402. |
brains were removed and processed to measure infarct volume, 70 kda heat shock protein (hsp70), glial fibrillary acidic protein (gfap) and vimentin (vim) immunoreactivity (ir), and apoptosis using terminal deoxynucleotidyl transferase (tdt)-mediated dutp-digoxigenin nick end-labeling (tunel) assay. |
2001-07-12 |
2023-08-12 |
rat |
| E Castigli, C Arcuri, L Giovagnoli, R Luciani, L Giovagnoli, T Secca, G L Gianfranceschi, V Bocchin. Interleukin-1beta induces apoptosis in GL15 glioblastoma-derived human cell line. American journal of physiology. Cell physiology. vol 279. issue 6. 2001-01-04. PMID:11078722. |
we correlated the degree of differentiation of gl15 cells with the apoptotic response: 1) 4',6-diamidino-2-phenylindole staining, combined with glial fibrillary acidic protein (gfap) immunofluorescence, showed that the cells with apoptotic nuclei express low levels of gfap; and 2) at 13 days of subculture, in a more differentiated state, gl15 cells did not respond with apoptosis to il-1beta. |
2001-01-04 |
2023-08-12 |
human |
| A E Morelli, A T Larregina, J Smith-Arica, R A Dewey, T D Southgate, B Ambar, A Fontana, M G Castro, P R Lowenstei. Neuronal and glial cell type-specific promoters within adenovirus recombinants restrict the expression of the apoptosis-inducing molecule Fas ligand to predetermined brain cell types, and abolish peripheral liver toxicity. The Journal of general virology. vol 80 ( Pt 3). 1999-04-15. PMID:10091995. |
the rads encoding fasl under the control of the non-cell type-specific miehcmv promoter induced acute generalized liver haemorrhage with hepatocyte apoptosis, while the rads containing the nse or gfap promoter sequences were completely non-toxic. |
1999-04-15 |
2023-08-12 |
mouse |