| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wei-Guang Wu, Yue-Cheng Yu, Ya-Qiong Chen, Xiu-Qin Ca. [Construction of RNA recombinant vector expressing STAT3 short hairpin and its effects on proliferation and apoptosis of SiHa cells]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. vol 24. issue 10. 2010-04-08. PMID:18845085. |
[construction of rna recombinant vector expressing stat3 short hairpin and its effects on proliferation and apoptosis of siha cells]. |
2010-04-08 |
2023-08-12 |
Not clear |
| Wei-Guang Wu, Yue-Cheng Yu, Ya-Qiong Chen, Xiu-Qin Ca. [Construction of RNA recombinant vector expressing STAT3 short hairpin and its effects on proliferation and apoptosis of SiHa cells]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. vol 24. issue 10. 2010-04-08. PMID:18845085. |
to investigate the effects of eukaryotic vector expressing short hairpin rna (shrna) of signal transducers and activators of transcription 3 (stat3) on the proliferation and apoptosis of siha cells. |
2010-04-08 |
2023-08-12 |
Not clear |
| Wen-Ling Shih, Ming-Huei Liao, Ping-Yuan Lin, Chi-I Chang, Hsueh-Ling Cheng, Feng-Ling Yu, Jeng-Woei Le. PI 3-kinase/Akt and STAT3 are required for the prevention of TGF-beta-induced Hep3B cell apoptosis by autocrine motility factor/phosphoglucose isomerase. Cancer letters. vol 290. issue 2. 2010-04-07. PMID:19819066. |
pi 3-kinase/akt and stat3 are required for the prevention of tgf-beta-induced hep3b cell apoptosis by autocrine motility factor/phosphoglucose isomerase. |
2010-04-07 |
2023-08-12 |
Not clear |
| Chao Tang, Hong-li Xue, Hai-bo Huang, Xiao-gang Wan. Tanshinone IIA inhibits constitutive STAT3 activation, suppresses proliferation, and induces apoptosis in rat C6 glioma cells. Neuroscience letters. vol 470. issue 2. 2010-04-06. PMID:20045721. |
tanshinone iia inhibits constitutive stat3 activation, suppresses proliferation, and induces apoptosis in rat c6 glioma cells. |
2010-04-06 |
2023-08-12 |
rat |
| Ping-Yuan Lin, Hung-Jen Liu, Ming-Huei Liao, Ching-Dong Chang, Chi-I Chang, Hsueh-Ling Cheng, Jeng-Woei Lee, Wen-Ling Shi. Activation of PI 3-kinase/Akt/NF-kappaB and Stat3 signaling by avian reovirus S1133 in the early stages of infection results in an inflammatory response and delayed apoptosis. Virology. vol 400. issue 1. 2010-04-02. PMID:20170934. |
activation of pi 3-kinase/akt/nf-kappab and stat3 signaling by avian reovirus s1133 in the early stages of infection results in an inflammatory response and delayed apoptosis. |
2010-04-02 |
2023-08-12 |
chicken |
| Jing Zhou, Choon-Nam Ong, Gang-Min Hur, Han-Ming She. Inhibition of the JAK-STAT3 pathway by andrographolide enhances chemosensitivity of cancer cells to doxorubicin. Biochemical pharmacology. vol 79. issue 9. 2010-04-01. PMID:20026083. |
for understanding the biological significance of the inhibitory effect of andro on stat3, we next investigated the effect of andro on doxorubicin-induced apoptosis in human cancer cells. |
2010-04-01 |
2023-08-12 |
human |
| Jing Zhou, Choon-Nam Ong, Gang-Min Hur, Han-Ming She. Inhibition of the JAK-STAT3 pathway by andrographolide enhances chemosensitivity of cancer cells to doxorubicin. Biochemical pharmacology. vol 79. issue 9. 2010-04-01. PMID:20026083. |
in our study the constitutive activation level of stat3 was found to be correlated to the resistance of cancer cells to doxorubicin-induced apoptosis. |
2010-04-01 |
2023-08-12 |
human |
| Julia Bollrath, Florian R Grete. IKK/NF-kappaB and STAT3 pathways: central signalling hubs in inflammation-mediated tumour promotion and metastasis. EMBO reports. vol 10. issue 12. 2010-03-30. PMID:19893576. |
by contrast, in tumorigenic cells, both nf-kappab and stat3 control apoptosis, and stat3 can also enhance proliferation. |
2010-03-30 |
2023-08-12 |
Not clear |
| Reeti Behera, Vinit Kumar, Kirti Lohite, Swapnil Karnik, Gopal C Kund. Activation of JAK2/STAT3 signaling by osteopontin promotes tumor growth in human breast cancer cells. Carcinogenesis. vol 31. issue 2. 2010-03-04. PMID:19926637. |
however, the molecular mechanism by which osteopontin (opn), a chemokine-like extracellular matrix-associated protein, regulates stat3 activation that leads to tumor progression and inhibits apoptosis in breast cancer cells is not well understood. |
2010-03-04 |
2023-08-12 |
mouse |
| Steven Fletcher, Joel A Drewry, Vijay M Shahani, Brent D G Page, Patrick T Gunnin. Molecular disruption of oncogenic signal transducer and activator of transcription 3 (STAT3) protein. Biochemistry and cell biology = Biochimie et biologie cellulaire. vol 87. issue 6. 2010-03-04. PMID:19935868. |
constitutively activated stat3 protein activity is routinely observed in human cancers, promoting uncontrolled cell proliferation and suppressing apoptosis. |
2010-03-04 |
2023-08-12 |
human |
| b' Aws Alshamsan, Samar Hamdy, John Samuel, Ayman O S El-Kadi, Afsaneh Lavasanifar, Hasan Uluda\\xc4\\x9. The induction of tumor apoptosis in B16 melanoma following STAT3 siRNA delivery with a lipid-substituted polyethylenimine. Biomaterials. vol 31. issue 6. 2010-03-03. PMID:19913908.' |
the induction of tumor apoptosis in b16 melanoma following stat3 sirna delivery with a lipid-substituted polyethylenimine. |
2010-03-03 |
2023-08-12 |
Not clear |
| Xing Fan, Leila Khaki, Thant S Zhu, Mary E Soules, Caroline E Talsma, Naheed Gul, Cheryl Koh, Jiangyang Zhang, Yue-Ming Li, Jarek Maciaczyk, Guido Nikkhah, Francesco Dimeco, Sara Piccirillo, Angelo L Vescovi, Charles G Eberhar. NOTCH pathway blockade depletes CD133-positive glioblastoma cells and inhibits growth of tumor neurospheres and xenografts. Stem cells (Dayton, Ohio). vol 28. issue 1. 2010-03-01. PMID:19904829. |
we found that notch pathway inhibition appears to deplete stem-like cancer cells through reduced proliferation and increased apoptosis associated with decreased akt and stat3 phosphorylation. |
2010-03-01 |
2023-08-12 |
mouse |
| Maureen M Sherry, Andrew Reeves, Julian K Wu, Brent H Cochra. STAT3 is required for proliferation and maintenance of multipotency in glioblastoma stem cells. Stem cells (Dayton, Ohio). vol 27. issue 10. 2010-02-17. PMID:19658181. |
signal transducer and activator of transcription 3 (stat3) regulates diverse cellular processes, including cell growth, differentiation, and apoptosis, and is frequently activated during tumorigenesis. |
2010-02-17 |
2023-08-12 |
Not clear |
| Maureen M Sherry, Andrew Reeves, Julian K Wu, Brent H Cochra. STAT3 is required for proliferation and maintenance of multipotency in glioblastoma stem cells. Stem cells (Dayton, Ohio). vol 27. issue 10. 2010-02-17. PMID:19658181. |
although stat3 inhibition can induce apoptosis in serum-derived gbm cell lines, this effect was not observed in gbm-scs grown in stem cell medium. |
2010-02-17 |
2023-08-12 |
Not clear |
| Hui Wang, Justin D Lathia, Qiulian Wu, Jialiang Wang, Zhizhong Li, John M Heddleston, Christine E Eyler, Jennifer Elderbroom, Joseph Gallagher, Jesse Schuschu, Jennifer MacSwords, Yiting Cao, Roger E McLendon, Xiao-Fan Wang, Anita B Hjelmeland, Jeremy N Ric. Targeting interleukin 6 signaling suppresses glioma stem cell survival and tumor growth. Stem cells (Dayton, Ohio). vol 27. issue 10. 2010-02-17. PMID:19658188. |
perturbation of il6 signaling in gscs attenuates signal transducers and activators of transcription three (stat3) activation, and small molecule inhibitors of stat3 potently induce gsc apoptosis. |
2010-02-17 |
2023-08-12 |
mouse |
| Jingchun Gao, Zhong Zheng, Bhupendra Rawal, Michael J Schell, Gerold Bepler, Eric B Haur. Mirk/Dyrk1B, a novel therapeutic target, mediates cell survival in non-small cell lung cancer cells. Cancer biology & therapy. vol 8. issue 17. 2010-02-12. PMID:19633423. |
mirk knockdown by small interfering rna induced cell apoptosis concomitant with upregulation of bak, a bcl-2 family member, and downregulation of signal transducers and activators of transcription 3 (stat3) tyrosine phosphorylation. |
2010-02-12 |
2023-08-12 |
mouse |
| Li Zhou, Ping Fu, Xiao R Huang, Fei Liu, Kar Neng Lai, Hui Y La. Activation of p53 promotes renal injury in acute aristolochic acid nephropathy. Journal of the American Society of Nephrology : JASN. vol 21. issue 1. 2010-02-03. PMID:19892935. |
aa induced dephosphorylation of stat3 and the subsequent activation of p53 and tec apoptosis. |
2010-02-03 |
2023-08-12 |
mouse |
| Li Zhou, Ping Fu, Xiao R Huang, Fei Liu, Kar Neng Lai, Hui Y La. Activation of p53 promotes renal injury in acute aristolochic acid nephropathy. Journal of the American Society of Nephrology : JASN. vol 21. issue 1. 2010-02-03. PMID:19892935. |
in contrast, overexpression of stat3, p53 inhibition, or p53 knockdown with small interfering rna all attenuated aa-induced tec apoptosis. |
2010-02-03 |
2023-08-12 |
mouse |
| Li Zhou, Ping Fu, Xiao R Huang, Fei Liu, Kar Neng Lai, Hui Y La. Activation of p53 promotes renal injury in acute aristolochic acid nephropathy. Journal of the American Society of Nephrology : JASN. vol 21. issue 1. 2010-02-03. PMID:19892935. |
taken together, these results suggest that aa induces tec death via apoptosis by dephosphorylation of stat3 and posttranslational activation of p53, supporting the hypothesis that p53 promotes renal injury in acute aan. |
2010-02-03 |
2023-08-12 |
mouse |
| Takuji Tanaka, Mariangela B M de Azevedo, Nelson Durán, Joel B Alderete, Francesco Epifano, Salvatore Genovese, Mayu Tanaka, Takahiro Tanaka, Massimo Curin. Colorectal cancer chemoprevention by 2 beta-cyclodextrin inclusion compounds of auraptene and 4'-geranyloxyferulic acid. International journal of cancer. vol 126. issue 4. 2010-02-01. PMID:19688830. |
the dietary administration with gofa/beta-cd and aur/beta-cd inhibited colonic inflammation and also modulated proliferation, apoptosis and the expression of several proinflammatory cytokines, such as nuclear factor-kappab, tumor necrosis factor-alpha, stat3, nf-e2-related factor 2, interleukin (il)-6 and il-1beta, which were induced in the adenocarcinomas. |
2010-02-01 |
2023-08-12 |
mouse |