| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| An Wang, Youbo Wang, Qinyun Ma, Xiaofeng Che. The carcinogenesis of esophageal squamous cell cancer is positively regulated by USP13 through WISP1 deubiquitination. BioFactors (Oxford, England). 2024-10-29. PMID:39468941. |
mass spectrometry, immunoprecipitation, and in vitro functional assays were conducted to explore the interaction between usp13 and wisp1 and to assess the effects of usp13 downregulation on cell proliferation, migration, invasion, epithelial-mesenchymal transition (emt), and apoptosis. |
2024-10-29 |
2024-10-31 |
mouse |
| An Wang, Youbo Wang, Qinyun Ma, Xiaofeng Che. The carcinogenesis of esophageal squamous cell cancer is positively regulated by USP13 through WISP1 deubiquitination. BioFactors (Oxford, England). 2024-10-29. PMID:39468941. |
downregulation of usp13 resulted in reduced wisp1 protein stability, decreased cell proliferation, migration, and emt, and increased apoptosis in vitro. |
2024-10-29 |
2024-10-31 |
mouse |
| Yixin Jiang, Xiaoli Fan, Yaling Yu, Hongfan Ge, Chengyin Liu, Yanyan Zhang, Lingyun Yu, Wen Yin, Zhenlei Zho. USP13 Overexpression in BMSCs Enhances Anti-Apoptotic Ability and Guards Against Methylprednisolone-Induced Osteonecrosis in Rats. Stem cells (Dayton, Ohio). 2024-10-26. PMID:39460600. |
usp13 also protected bmscs from mps-induced apoptosis by modulating pten and reducing akt phosphorylation. |
2024-10-26 |
2024-10-29 |
rat |
| Yuchu Yuan, Meizhu Xue, Feng Zhou, Lifang G. USP13 promotes acute myeloid leukemia cell proliferation and autophagy by promoting ATG5. Tissue & cell. vol 91. 2024-08-31. PMID:39216303. |
to elucidate the role of usp13 in acute myeloid leukemia (aml) by investigating its effects on cell growth, apoptosis and autophagy, and to explore the underlying mechanisms. |
2024-08-31 |
2024-09-04 |
Not clear |
| Hao Yan, Xiangliang Huang, Jiangxin Xu, Ying Zhang, Jiajia Chen, Zhifei Xu, Hui Li, Zeng Wang, Xiaochun Yang, Bo Yang, Qiaojun He, Peihua Lu. Chloroquine Intervenes Nephrotoxicity of Nilotinib through Deubiquitinase USP13-Mediated Stabilization of Bcl-XL. Advanced science (Weinheim, Baden-Wurttemberg, Germany). 2023-07-14. PMID:37452432. |
additionally, it is found that usp13 abrogates cell apoptosis by preventing excessive ubiquitin-proteasome degradation of bcl-xl. |
2023-07-14 |
2023-08-14 |
Not clear |
| Zhen Zhang, Kaiping Deng, Ziqi Kang, Feng Wang, Yixuan Fa. MicroRNA profiling reveals miR-145-5p inhibits goat myoblast differentiation by targeting the coding domain sequence of USP13. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36. issue 7. 2022-05-31. PMID:35635726. |
taken together, these results revealed a novel pathway in skeletal muscle development in which mir-145-5p targets cds region of usp13 to regulate differentiation and apoptosis of gpms. |
2022-05-31 |
2023-08-13 |
Not clear |
| Shuaishuai Hu, Shaocheng Bai, Yingying Dai, Naisu Yang, Jiali Li, Xiyu Zhang, Fan Wang, Bohao Zhao, Guolian Bao, Yang Chen, Xinsheng W. Deubiquitination of MITF-M Regulates Melanocytes Proliferation and Apoptosis. Frontiers in molecular biosciences. vol 8. 2021-06-29. PMID:34179099. |
in conclusion, the mitf-m level was regulated by usp13 deubiquitinase in melanocytes, affecting melanocytes proliferation and apoptosis. |
2021-06-29 |
2023-08-13 |
Not clear |
| Jianming Huang, Zhiyang Ye, Jun Wang, Qichuan Chen, Danlei Huang, Haoyuan Li. USP13 mediates PTEN to ameliorate osteoarthritis by restraining oxidative stress, apoptosis and inflammation via AKT-dependent manner. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 133. 2021-02-24. PMID:33378983. |
usp13 mediates pten to ameliorate osteoarthritis by restraining oxidative stress, apoptosis and inflammation via akt-dependent manner. |
2021-02-24 |
2023-08-13 |
mouse |
| Jianming Huang, Zhiyang Ye, Jun Wang, Qichuan Chen, Danlei Huang, Haoyuan Li. USP13 mediates PTEN to ameliorate osteoarthritis by restraining oxidative stress, apoptosis and inflammation via AKT-dependent manner. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 133. 2021-02-24. PMID:33378983. |
we then showed that over-expressing usp13 markedly suppressed inflammatory response, oxidative stress and apoptosis in h-flss upon il-1β or tnf-α challenge, whereas usp13 knockdown exhibited detrimental effects. |
2021-02-24 |
2023-08-13 |
mouse |