| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R Kyo, N Nakahata, I Sakakibara, M Kubo, Y Ohizum. Baicalin and baicalein, constituents of an important medicinal plant, inhibit intracellular Ca2+ elevation by reducing phospholipase C activity in C6 rat glioma cells. The Journal of pharmacy and pharmacology. vol 50. issue 10. 1999-01-22. PMID:9821667. |
this study was undertaken to clarify the effects of baicalin and baicalein, flavonoids isolated from an important medicinal plant scutellariae radix (the root of scutellaria baicalensis georgi), on glial cell function using c6 rat glioma cells. |
1999-01-22 |
2023-08-12 |
rat |
| D R Friedlander, P A Brittis, T Sakurai, B Shif, W Wirchansky, G Fishell, M Grume. Generation of a radial-like glial cell line. Journal of neurobiology. vol 37. issue 2. 1999-01-19. PMID:9805274. |
in experiments designed to study a mutant form of receptor protein tyrosine phosphatase beta, we isolated a subclone of c6 called c6-r which, like radial glia, assumes a highly polarized radial-like morphology in culture. |
1999-01-19 |
2023-08-12 |
rat |
| D R Friedlander, P A Brittis, T Sakurai, B Shif, W Wirchansky, G Fishell, M Grume. Generation of a radial-like glial cell line. Journal of neurobiology. vol 37. issue 2. 1999-01-19. PMID:9805274. |
these results suggest that we have generated a stable cell line from c6 glioma which has adopted certain key features of radial glia, including the ability to promote neuronal migration in culture and integrate radially in vivo in response to local cues. |
1999-01-19 |
2023-08-12 |
rat |
| C Brodie, I Kuperstein, P Acs, P M Blumber. Differential role of specific PKC isoforms in the proliferation of glial cells and the expression of the astrocytic markers GFAP and glutamine synthetase. Brain research. Molecular brain research. vol 56. issue 1-2. 1999-01-14. PMID:9602083. |
in this study, we explored the role of specific protein kinase c (pkc) isoforms in glial cell proliferation and on the expression of the astrocytic markers gfap and glutamine synthetase using c6 cells as a model. |
1999-01-14 |
2023-08-12 |
Not clear |
| J Pfeuffer, S Bröer, A Bröer, M Lechte, U Flögel, D Leibfrit. Expression of aquaporins in Xenopus laevis oocytes and glial cells as detected by diffusion-weighted 1H NMR spectroscopy and photometric swelling assay. Biochimica et biophysica acta. vol 1448. issue 1. 1999-01-06. PMID:9824661. |
with this, the mrna encoding aqp1 could be detected in primary cultures and glial cell lines, whereas aqp4 mrna was found in astroglia-rich primary cultures, but not in f98 and c6 cells. |
1999-01-06 |
2023-08-12 |
xenopus_laevis |
| E A Mazzio, N Harris, K F Solima. Food constituents attenuate monoamine oxidase activity and peroxide levels in C6 astrocyte cells. Planta medica. vol 64. issue 7. 1998-12-16. PMID:9810264. |
results of this investigation indicate that compounds which inhibit c6 glial cell mao enzyme activity or scavenge peroxide product include chlorogenic acid, (+)-catechin, taxifolin, (-)-epigallocatechin gallate (egcg), fisetin, coenzyme q0, curcumin, sesamol, morin, sesame oil, silymarin, green tea, ferulic acid, caffeic acid, and rutin hydrate. |
1998-12-16 |
2023-08-12 |
rat |
| S J Myers, J Peters, Y Huang, M B Comer, F Barthel, R Dingledin. Transcriptional regulation of the GluR2 gene: neural-specific expression, multiple promoters, and regulatory elements. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 18. issue 17. 1998-09-09. PMID:9712644. |
when glur2 promoter activity was investigated by plasmid transfection into cultured cortical neurons, cortical glia, and c6 glioma cells, the promoter construct with the strongest activity, per transfected cell, was 29.4-fold (+/- 3.7) more active in neurons than in non-neural cells. |
1998-09-09 |
2023-08-12 |
rat |
| C Volk, T Albert, O S Kempsk. A proton-translocating H+-ATPase is involved in C6 glial pH regulation. Biochimica et biophysica acta. vol 1372. issue 1. 1998-08-05. PMID:9651471. |
we therefore investigated whether a h+-translocating atpase is involved in glial phi homeostasis using an established glial cell line (c6 glioma). |
1998-08-05 |
2023-08-12 |
Not clear |
| M R Cookson, N D Slamon, V W Pentreat. Glutathione modifies the toxicity of triethyltin and trimethyltin in C6 glioma cells. Archives of toxicology. vol 72. issue 4. 1998-07-08. PMID:9587013. |
it has been demonstrated that exposure to mercury or cadmium compounds causes alterations in the glutathione system in a model glial cell line, c6. |
1998-07-08 |
2023-08-12 |
Not clear |
| H Sakai, S Nakashima, S Yoshimura, Y Nishimura, N Sakai, Y Nozaw. Molecular cloning of a cDNA encoding a serine protease homologous to complement C1s precursor from rat C6 glial cells and its expression during glial differentiation. Gene. vol 209. issue 1-2. 1998-05-13. PMID:9524231. |
a cdna of rat c6 cells was cloned, which was considered to be involved in glial cell differentiation induced by dibutyryl cyclic amp and theophylline. |
1998-05-13 |
2023-08-12 |
human |
| M Alvarez-Dolado, J M González-Sancho, J Bernal, A Muño. Developmental expression of the tenascin-C is altered by hypothyroidism in the rat brain. Neuroscience. vol 84. issue 1. 1998-05-08. PMID:9580330. |
suggesting a direct cellular effect, thyroid hormone also decreases tenascin-c expression in two glial cell lines (c6, b3.1) expressing thyroid receptors. |
1998-05-08 |
2023-08-12 |
rat |
| J Ramos-Castañeda, J L Imbert, B L Barrón, C Ramo. A 65-kDa trypsin-sensible membrane cell protein as a possible receptor for dengue virus in cultured neuroblastoma cells. Journal of neurovirology. vol 3. issue 6. 1998-04-20. PMID:9475115. |
infection of n1e-115 cells was diminished with trypsin treatment but not with neuraminidase or endoglycosidase h. partially purified cell membrane proteins from neuroblastoma cells were analyzed by the virus overlay protein blot assay (vopba), and a single band migrating at 65 kda was detected in mouse and human neuroblastoma cells but not in c6, a non-susceptible rat glial cell line which was included as a negative control. |
1998-04-20 |
2023-08-12 |
mouse |
| A Sedo, R Malík, E Krepel. Dipeptidyl peptidase IV in C6 rat glioma cell line differentiation. Biological chemistry. vol 379. issue 1. 1998-04-10. PMID:9504715. |
the c6 rat glioma cell line is broadly used as a model in studies of glial cell differentiation. |
1998-04-10 |
2023-08-12 |
rat |
| A N Verity, T L Wyatt, B Hajos, R M Eglen, P A Baecker, R M Johnso. Regulation of glial cell line-derived neurotrophic factor release from rat C6 glioblastoma cells. Journal of neurochemistry. vol 70. issue 2. 1998-02-24. PMID:9453547. |
regulation of glial cell line-derived neurotrophic factor release from rat c6 glioblastoma cells. |
1998-02-24 |
2023-08-12 |
rat |
| A N Verity, T L Wyatt, B Hajos, R M Eglen, P A Baecker, R M Johnso. Regulation of glial cell line-derived neurotrophic factor release from rat C6 glioblastoma cells. Journal of neurochemistry. vol 70. issue 2. 1998-02-24. PMID:9453547. |
we have monitored glial cell line-derived neurotrophic factor (gdnf) secretion from rat c6 glioblastoma cells by elisa. |
1998-02-24 |
2023-08-12 |
rat |
| K Pahan, F G Sheikh, M Khan, A M Namboodiri, I Sing. Sphingomyelinase and ceramide stimulate the expression of inducible nitric-oxide synthase in rat primary astrocytes. The Journal of biological chemistry. vol 273. issue 5. 1998-02-23. PMID:9446561. |
similar to astrocytes, smase or ceramide analogs also stimulated the lps- and cytokine-mediated expression of inos in the c6 glial cell line. |
1998-02-23 |
2023-08-12 |
rat |
| L Goy. Steroid and protein regulators of glial cell proliferation. Advances in experimental medicine and biology. vol 429. 1998-01-29. PMID:9413579. |
the data presented in this chapter show the plasticity of c6 glioma to the differentiating effect of various growth factors, especially insulin and dexamethasone, and confirms c6 glioma cell line as a useful model for studies on glial cell properties and proliferation in vitro. |
1998-01-29 |
2023-08-12 |
rat |
| M L Wu, E F Kao, I H Liu, B S Wang, S Y Lin-Shia. Capacitative Ca2+ influx in glial cells is inhibited by glycolytic inhibitors. Glia. vol 21. issue 3. 1997-12-22. PMID:9383040. |
since this ca2+ influx in glial cells has not been thoroughly investigated, we have used c6 glioma cells as a glial cell model to study this phenomenon. |
1997-12-22 |
2023-08-12 |
Not clear |
| M Niwa, N Nakamura, K Kitajima, M Ueda, Y Tsutsumishita, S Futaki, Y Takaish. Benzoquinones inhibit the expression of inducible nitric oxide synthase gene. Biochemical and biophysical research communications. vol 239. issue 2. 1997-11-17. PMID:9344836. |
benzoquinones inhibited the production of no induced by lps and gamma-ifn in c6 glia cells. |
1997-11-17 |
2023-08-12 |
Not clear |
| Y Qian, E Tiffany-Castiglioni, E D Harri. A Menkes P-type ATPase involved in copper homeostasis in the central nervous system of the rat. Brain research. Molecular brain research. vol 48. issue 1. 1997-11-10. PMID:9379850. |
these data establish that a menkes-type cu-transporting atpase is expressed in rat c6 and pc12 cells and strongly support the hypothesis that both neurons and glia are involved in maintaining cu homeostasis in the central nervous system. |
1997-11-10 |
2023-08-12 |
mouse |