Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Erika Garay, Sean P J Whelan, Rebecca M DuBois, Sara M O'Rourke, Angel Eduardo Salgado-Escobar, José Esteban Muñoz-Medina, Carlos F Arias, Susana Lópe. Immune response to SARS-CoV-2 variants after immunization with different vaccines in Mexico. Epidemiology and infection. vol 152. 2024-02-19. PMID:38312015. |
a follow-up of 4 months post-vaccination showed a drop in antibody titre, with about 20% of the infection-naive and 100% of sars-cov-2 pre-exposed participants with detectable neutralization capacity against alpha pseudovirus (alpha-pv) and delta pv (delta-pv). |
2024-02-19 |
2024-02-21 |
human |
Dong Yang, Jasper Fuk-Woo Chan, Chaemin Yoon, Tsz-Yat Luk, Huiping Shuai, Yuxin Hou, Xiner Huang, Bingjie Hu, Yue Chai, Terrence Tsz-Tai Yuen, Yuanchen Liu, Tianrenzheng Zhu, Huan Liu, Jialu Shi, Yang Wang, Yixin He, Ko-Yung Sit, Wing-Kuk Au, Anna Jinxia Zhang, Shuofeng Yuan, Bao-Zhong Zhang, Yao-Wei Huang, Hin Ch. Type-II IFN inhibits SARS-CoV-2 replication in human lung epithelial cells and ex vivo human lung tissues through indoleamine 2,3-dioxygenase-mediated pathways. Journal of medical virology. vol 96. issue 2. 2024-02-19. PMID:38373201. |
mechanistically, we show that overexpression of indoleamine 2,3-dioxygenase 1 (ido1), which is most profoundly induced by ifnγ, substantially restricts the replication of ancestral sars-cov-2 and the alpha and delta variants. |
2024-02-19 |
2024-02-22 |
human |
Liina Hannula, Suvi Kuivanen, Jonathan Lasham, Ravi Kant, Lauri Kareinen, Mariia Bogacheva, Tomas Strandin, Tarja Sironen, Jussi Hepojoki, Vivek Sharma, Petri Saviranta, Anja Kipar, Olli Vapalahti, Juha T Huiskonen, Ilona Rissane. Nanobody engineering for SARS-CoV-2 neutralization and detection. Microbiology spectrum. 2024-02-16. PMID:38363137. |
through fusion of nanobody domains that target distinct binding sites, we engineered multimodular nanobody constructs that neutralize wild-type sars-cov-2 and the alpha and delta variants at high potency, with ic |
2024-02-16 |
2024-02-18 |
Not clear |
Ali H Shilleh, Katrina Viloria, Johannes Broichhagen, Jonathan E Campbell, David J Hodso. GLP1R and GIPR expression and signaling in pancreatic alpha cells, beta cells and delta cells. Peptides. 2024-02-15. PMID:38360354. |
glp1r and gipr expression and signaling in pancreatic alpha cells, beta cells and delta cells. |
2024-02-15 |
2024-02-18 |
Not clear |
Ali H Shilleh, Katrina Viloria, Johannes Broichhagen, Jonathan E Campbell, David J Hodso. GLP1R and GIPR expression and signaling in pancreatic alpha cells, beta cells and delta cells. Peptides. 2024-02-15. PMID:38360354. |
therapeutic targeting of glp1r and gipr restores blood glucose levels in part by influencing beta cell, alpha cell and delta cell function. |
2024-02-15 |
2024-02-18 |
Not clear |
Ali H Shilleh, Katrina Viloria, Johannes Broichhagen, Jonathan E Campbell, David J Hodso. GLP1R and GIPR expression and signaling in pancreatic alpha cells, beta cells and delta cells. Peptides. 2024-02-15. PMID:38360354. |
while glp1r is largely a beta cell-specific marker within the islet, gipr is expressed in alpha cells, beta cells, and (possibly) delta cells. |
2024-02-15 |
2024-02-18 |
Not clear |
Shawn S Clausen, Jessica H Murray, Shauna L Stahlma. Ivermectin prescription fill rates among U.S. Military members during the coronavirus disease 2019 (COVID-19) pandemic. MSMR. vol 31. issue 1. 2024-02-15. PMID:38359347. |
ivermectin prescription fill rates increased among acsm during periods of alpha and delta coronavirus variant predominance, but not during the predominance of the omicron variant. |
2024-02-15 |
2024-02-18 |
Not clear |
Leandro P L Jacob, Sydney M Bailes, Stephanie D Williams, Carsen Stringer, Laura D Lewi. Distributed fMRI dynamics predict distinct EEG rhythms across sleep and wakefulness. bioRxiv : the preprint server for biology. 2024-02-14. PMID:38352426. |
using simultaneous eeg and fast fmri in subjects drifting between sleep and wakefulness, we developed a machine learning approach to investigate which brainwide fmri dynamics predict alpha (8-12 hz) and delta (1-4 hz) rhythms. |
2024-02-14 |
2024-02-16 |
human |
Leandro P L Jacob, Sydney M Bailes, Stephanie D Williams, Carsen Stringer, Laura D Lewi. Distributed fMRI dynamics predict distinct EEG rhythms across sleep and wakefulness. bioRxiv : the preprint server for biology. 2024-02-14. PMID:38352426. |
these results identify distributed networks that predict delta and alpha rhythms, and establish a computational framework for investigating fmri brainwide dynamics underlying eeg oscillations. |
2024-02-14 |
2024-02-16 |
human |
Abhishek Mallela, Ye Chen, Yen Ting Lin, Ely F Miller, Jacob Neumann, Zhili He, Kathryn E Nelson, Richard G Posner, William S Hlavace. Impacts of Vaccination and Severe Acute Respiratory Syndrome Coronavirus 2 Variants Alpha and Delta on Coronavirus Disease 2019 Transmission Dynamics in Four Metropolitan Areas of the United States. Bulletin of mathematical biology. vol 86. issue 3. 2024-02-14. PMID:38353870. |
impacts of vaccination and severe acute respiratory syndrome coronavirus 2 variants alpha and delta on coronavirus disease 2019 transmission dynamics in four metropolitan areas of the united states. |
2024-02-14 |
2024-02-16 |
Not clear |
Abhishek Mallela, Ye Chen, Yen Ting Lin, Ely F Miller, Jacob Neumann, Zhili He, Kathryn E Nelson, Richard G Posner, William S Hlavace. Impacts of Vaccination and Severe Acute Respiratory Syndrome Coronavirus 2 Variants Alpha and Delta on Coronavirus Disease 2019 Transmission Dynamics in Four Metropolitan Areas of the United States. Bulletin of mathematical biology. vol 86. issue 3. 2024-02-14. PMID:38353870. |
to characterize coronavirus disease 2019 (covid-19) transmission dynamics in each of the metropolitan statistical areas (msas) surrounding dallas, houston, new york city, and phoenix in 2020 and 2021, we extended a previously reported compartmental model accounting for effects of multiple distinct periods of non-pharmaceutical interventions by adding consideration of vaccination and severe acute respiratory syndrome coronavirus 2 (sars-cov-2) variants alpha (lineage b.1.1.7) and delta (lineage b.1.617.2). |
2024-02-14 |
2024-02-16 |
Not clear |
Abhishek Mallela, Ye Chen, Yen Ting Lin, Ely F Miller, Jacob Neumann, Zhili He, Kathryn E Nelson, Richard G Posner, William S Hlavace. Impacts of Vaccination and Severe Acute Respiratory Syndrome Coronavirus 2 Variants Alpha and Delta on Coronavirus Disease 2019 Transmission Dynamics in Four Metropolitan Areas of the United States. Bulletin of mathematical biology. vol 86. issue 3. 2024-02-14. PMID:38353870. |
in the process, we obtained estimates of the relative infectiousness of alpha and delta as well as their takeoff times in each msa (the times at which sustained transmission began). |
2024-02-14 |
2024-02-16 |
Not clear |
Zhaobin Xu, Qingzhi Peng, Jian Song, Hongmei Zhang, Dongqing Wei, Jacques Demongeot, Qiangcheng Zen. Bioinformatic analysis of defective viral genomes in SARS-CoV-2 and its impact on population infection characteristics. Frontiers in immunology. vol 15. 2024-02-13. PMID:38348041. |
specifically, the proportion of intact genome in the omicron strain surpassed that of the delta and alpha strains. |
2024-02-13 |
2024-02-15 |
Not clear |
Zhaobin Xu, Qingzhi Peng, Jian Song, Hongmei Zhang, Dongqing Wei, Jacques Demongeot, Qiangcheng Zen. Bioinformatic analysis of defective viral genomes in SARS-CoV-2 and its impact on population infection characteristics. Frontiers in immunology. vol 15. 2024-02-13. PMID:38348041. |
this observation effectively elucidates the heightened infectiousness of the omicron strain compared to the delta and alpha strains. |
2024-02-13 |
2024-02-15 |
Not clear |
Abdelmounim Essabbar, Safae El Mazouri, Nassma Boumajdi, Houda Bendani, Tarik Aanniz, Ouadghiri Mouna, Belyamani Lahcen, Azeddine Ibrahim. Temporal Dynamics and Genomic Landscape of SARS-CoV-2 After Four Years of Evolution. Cureus. vol 16. issue 2. 2024-02-08. PMID:38327721. |
notably, the emergence of the alpha and delta variants in 2021 was followed by the subsequent dominance of omicron clade variants that have branched into several recombinant variants in 2022, marking a significant shift in the viral landscape. |
2024-02-08 |
2024-02-10 |
Not clear |
Masaharu Okano, Jiro Miyamae, Kohei Sakurai, Takuya Yamaguchi, Ren Uehara, Fumihiko Katakura, Tadaaki Moritom. Subgenomic T cell receptor alpha and delta (TRA/TRD) loci in common carp. Fish & shellfish immunology. 2024-02-07. PMID:38325591. |
subgenomic t cell receptor alpha and delta (tra/trd) loci in common carp. |
2024-02-07 |
2024-02-10 |
zebrafish |
Masaharu Okano, Jiro Miyamae, Kohei Sakurai, Takuya Yamaguchi, Ren Uehara, Fumihiko Katakura, Tadaaki Moritom. Subgenomic T cell receptor alpha and delta (TRA/TRD) loci in common carp. Fish & shellfish immunology. 2024-02-07. PMID:38325591. |
in jawed vertebrates, the t cell receptor alpha (tra) and delta (trd) genes, which encode the trα and trδ chains, respectively, are located as a nested structure on a single chromosome. |
2024-02-07 |
2024-02-10 |
zebrafish |
Nicholas P Pinkhover, Kerriann M Pontbriand, Kelli P Fletcher, Eduardo Sanchez, Kenneth Okello, Liam M Garvey, Alex Pum, Kurvin Li, Gabriel DeOliveira, Teddie Proctor, Jelena D M Feenstra, Océane Sorel, Manoj Gandhi, Jared R Auclai. Comparison of analytical performance and economic value of two biosurveillance methods for tracking SARS-COV-2 variants of concern. Microbiology spectrum. vol 12. issue 2. 2024-02-07. PMID:38206048. |
the aim of this study was to compare the analytical performance and economic feasibility of wgs and pcr mutation panels for distinguishing six known vocs: alpha (b.1.1.7 and q.4), gamma (p.1), delta (b.1.617.2 and ay.4.2), and omicron. |
2024-02-07 |
2024-02-09 |
Not clear |
Jaber Alizadehgoradel, Behnam Molaei, Khandan Barzegar Jalali, Asghar Pouresmali, Kiomars Sharifi, Amir-Homayun Hallajian, Vahid Nejati, Benedikt Glinski, Carmelo M Vicario, Michael A Nitsche, Mohammad Ali Salehineja. Targeting the prefrontal-supplementary motor network in obsessive-compulsive disorder with intensified electrical stimulation in two dosages: a randomized, controlled trial. Translational psychiatry. vol 14. issue 1. 2024-02-05. PMID:38316750. |
both protocols increased alpha oscillatory power, and the 2-ma protocol decreased delta power as well. |
2024-02-05 |
2024-02-09 |
Not clear |
Ornella La Fortune Tchoupou Saha, Grégory Dubourg, Abdourahamane Yacouba, Raphael Tola, Didier Raoult, Jean-Christophe Lagie. Description of nasopharyngeal bacterial pathogens associated with different SARS-CoV-2 variants. Microbial pathogenesis. 2024-02-02. PMID:38307371. |
in this study, we used multiplex pathogen-specific pcr to analyse the presence of nasopharyngeal bacterial pathogens from 400 sars-cov-2 positive patients (equally distributed in the four sars-cov-2 variants studied: b.1.1.7 (alpha), b.1 .617.2 (delta), b.1.160 (marseille-4), and b.1.1.529 (omicron)). |
2024-02-02 |
2024-02-05 |
human |