Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Xin Xu, Lisa A Murph. Fast and sensitive LC-MS/MS method for quantification of cannabinoids and their metabolites in plasma of cattle fed hemp. Journal of separation science. 2023-10-31. PMID:37904320. |
furthermore, the study revealed that 7-carboxy cannabidiol, a metabolite of cannabidiol, was the predominant cannabinoid present in the cattle plasma throughout the feeding period, which could remain detectable for weeks after the hemp feeding had ended. |
2023-10-31 |
2023-11-08 |
cattle |
Nadia Boachie, Erin Gaudette, Richard P Bazinet, Lin Lin, Rachel F Tyndale, Esmaeil Mansouri, Marilyn A Huestis, Junchao Tong, Bernard Le Foll, Stephen J Kish, Tony P George, Isabelle Boilea. Circulating Endocannabinoids and N-Acylethanolamines in Individuals with Cannabis Use Disorder-Preliminary Findings. Brain sciences. vol 13. issue 10. 2023-10-30. PMID:37891745. |
although chronic cannabis use is associated with endocannabinoid system changes, the status of circulating endocannabinoids and related naes in people with cannabis use disorder (cud) is uncertain. |
2023-10-30 |
2023-11-08 |
Not clear |
Václav Trojan, Leoš Landa, Alexandra Šulcová, Jiří Slíva, Radovan Hři. The Main Therapeutic Applications of Cannabidiol (CBD) and Its Potential Effects on Aging with Respect to Alzheimer's Disease. Biomolecules. vol 13. issue 10. 2023-10-30. PMID:37892128. |
presently, attention is paid to two main cannabinoids: delta-9-tetrahydrocannabinol (thc) and cannabidiol (cbd). |
2023-10-30 |
2023-11-08 |
Not clear |
Jiangyinzi Shang, Sophie Hines, Meagan J Makarczyk, Hang Lin, MaCalus V Hogan, Alan Ya. Influence of the Synthetic Cannabinoid Agonist on Normal and Inflamed Cartilage: An In Vitro Study. Biomolecules. vol 13. issue 10. 2023-10-30. PMID:37892184. |
recent studies in animal models of arthritis showed that cannabinoids, a group of compounds produced from marijuana, may attenuate joint damage. |
2023-10-30 |
2023-11-08 |
human |
Jiangyinzi Shang, Sophie Hines, Meagan J Makarczyk, Hang Lin, MaCalus V Hogan, Alan Ya. Influence of the Synthetic Cannabinoid Agonist on Normal and Inflamed Cartilage: An In Vitro Study. Biomolecules. vol 13. issue 10. 2023-10-30. PMID:37892184. |
we first examined the influence of marijuana byproducts on normal cartilage by treating chondrocyte-derived tissues with a synthetic cannabinoid agonist, win-55,212-2 (win), at different concentrations ranging from 0.01 to 10 µm. |
2023-10-30 |
2023-11-08 |
human |
Zach J Leinen, Rahul Mohan, Lakmini S Premadasa, Arpan Acharya, Mahesh Mohan, Siddappa N Byraredd. Therapeutic Potential of Cannabis: A Comprehensive Review of Current and Future Applications. Biomedicines. vol 11. issue 10. 2023-10-30. PMID:37893004. |
the discovery of the endocannabinoid system, which interacts with cannabis phytoconstituents, has scientifically explained how cannabis affects the human immune system, including the central nervous system (cns). |
2023-10-30 |
2023-11-08 |
human |
Zach J Leinen, Rahul Mohan, Lakmini S Premadasa, Arpan Acharya, Mahesh Mohan, Siddappa N Byraredd. Therapeutic Potential of Cannabis: A Comprehensive Review of Current and Future Applications. Biomedicines. vol 11. issue 10. 2023-10-30. PMID:37893004. |
by researching current research and clinical studies, we probe into how cannabinoids like Δ9-tetrahydrocannabinol (thc) and cannabidiol (cbd) help to manage conditions ranging from chronic pain, persistent inflammation, cancer, inflammatory bowel disease, and neurological disorders to even viral diseases such as human immunodeficiency virus (hiv), sars-cov-2. |
2023-10-30 |
2023-11-08 |
human |
b' Maja Amid\\xc5\\xbei\\xc4\\x87, Jelena Banovi\\xc4\\x87 Fuentes, Jovica Banovi\\xc4\\x87, Ljilja Torovi\\xc4\\x8. Notifications and Health Consequences of Unauthorized Pharmaceuticals in Food Supplements. Pharmacy (Basel, Switzerland). vol 11. issue 5. 2023-10-27. PMID:37888499.' |
the most "popular" pharmaceuticals for the adulteration of food supplements were phosphodiesterase-5 inhibitors (235 records); anorexics and laxatives (76), including sibutramine and its active metabolite n-didesmethyl sibutramine, phenolphthalein and 2,4-dinitrophenol; stimulants, among which 1,3-dimethylamine (97), and synephrine (53) were the most numerous; nootropic drugs (24); anabolics and prohormones (16); and cannabinoid cannabidiol (14) (pending authorization as a novel food ingredient). |
2023-10-27 |
2023-11-08 |
Not clear |
Orrin Devinsky, Nicholas A Jones, Mark O Cunningham, B Ashan P Jayaskera, Sasha Devore, Benjamin J Whalle. Cannabinoid treatments in epilepsy and seizure disorders. Physiological reviews. 2023-10-26. PMID:37882730. |
in the last few decades, preclinical animal studies and clinical investigations have established the role of cannabidiol (cbd) in treating epilepsy and seizures and support potential therapeutic benefits for cannabinoids in other neurological and psychiatric disorders. |
2023-10-26 |
2023-11-08 |
Not clear |
Thomas Herdegen, Ingolf Cascorb. Drug Interactions of Tetrahydrocannabinol and Cannabidiol in Cannabinoid Drugs: Recommendations for Clinical Practice. Deutsches Arzteblatt international. issue Forthcoming. 2023-10-24. PMID:37874128. |
drug interactions of tetrahydrocannabinol and cannabidiol in cannabinoid drugs: recommendations for clinical practice. |
2023-10-24 |
2023-11-08 |
Not clear |
Thomas Herdegen, Ingolf Cascorb. Drug Interactions of Tetrahydrocannabinol and Cannabidiol in Cannabinoid Drugs: Recommendations for Clinical Practice. Deutsches Arzteblatt international. issue Forthcoming. 2023-10-24. PMID:37874128. |
cannabinoid drugs containing tetrahydrocannabinol (thc), or its structural analogues, as monotherapeutic agents or as extracts or botanical preparations with or without cannabidiol (cbd) are often prescribed to multimorbid patients who are taking multiple drugs. |
2023-10-24 |
2023-11-08 |
Not clear |
Sascha K Manier, Johannes Angert Valdiviezo, Aline C Vollmer, Niels Eckstein, Markus R Meye. Analytical toxicology of the semi-synthetic cannabinoid hexahydrocannabinol studied in human samples, pooled human liver S9 fraction, rat samples, and drug product using HPLC-HRMS/MS. Journal of analytical toxicology. 2023-10-21. PMID:37864499. |
hexahydrocannabinol (hhc) is an emerging semi-synthetic cannabinoid, that is obtained from cyclization of cannabidiol and subsequent hydrogenation. |
2023-10-21 |
2023-11-08 |
human |
Albert Stuart Reece, Gary Kenneth Huls. Perturbation of 3D nuclear architecture, epigenomic aging and dysregulation, and cannabinoid synaptopathy reconfigures conceptualization of cannabinoid pathophysiology: part 2-Metabolome, immunome, synaptome. Frontiers in psychiatry. vol 14. 2023-10-20. PMID:37854446. |
for these reasons, a comprehensive appreciation of cannabinoid pathophysiology necessitates a coordinated multiomics investigation of cannabinoid genome-epigenome-transcriptome-metabolome-immunome, chromatin conformation, and 3d nuclear architecture which therefore form the proper mechanistic underpinning for major new and concerning epidemiological findings relating to cannabis exposure. |
2023-10-20 |
2023-11-08 |
Not clear |
Chloe I Rogers, Carly R Pacanowsk. The relationship between cannabis and anorexia nervosa: a scoping review. Journal of eating disorders. vol 11. issue 1. 2023-10-20. PMID:37858278. |
this scoping review explores the endocannabinoid system (ecs), benefits/harms/null effects of cannabinoid treatment, and harms of cannabis use in an. |
2023-10-20 |
2023-11-08 |
Not clear |
María Andrea Arnanz, Samuel Ruiz de Martín Esteban, Ana María Martínez Relimpio, Neta Rimmerman, Nurit Tweezer Zaks, María Teresa Grande, Julián Romer. Effects of Chronic, Low-Dose Cannabinoids, Cannabidiol, Delta-9-Tetrahydrocannabinol and a Combination of Both, on Amyloid Pathology in the 5xFAD Mouse Model of Alzheimer's Disease. Cannabis and cannabinoid research. 2023-10-20. PMID:37862567. |
effects of chronic, low-dose cannabinoids, cannabidiol, delta-9-tetrahydrocannabinol and a combination of both, on amyloid pathology in the 5xfad mouse model of alzheimer's disease. |
2023-10-20 |
2023-11-08 |
mouse |
R Scott Duncan, Sean M Riordan, Matthew C Gernon, Peter Koule. Cannabinoids and endocannabinoids as therapeutics for nervous system disorders: preclinical models and clinical studies. Neural regeneration research. vol 19. issue 4. 2023-10-16. PMID:37843213. |
cannabinoids are lipophilic substances derived from cannabis sativa that can exert a variety of effects in the human body. |
2023-10-16 |
2023-11-08 |
human |
Dinesh Thapa, Leon N Warne, Marco Falasc. Pharmacohistory of Cannabis Use-A New Possibility in Future Drug Development for Gastrointestinal Diseases. International journal of molecular sciences. vol 24. issue 19. 2023-10-14. PMID:37834122. |
nevertheless, the discovery of tetrahydrocannabinol (thc), the primary psychoactive compound in cannabis, and the endocannabinoid system renewed scientific interest in understanding the role of cannabis in modulating different conditions, including gastrointestinal disorders. |
2023-10-14 |
2023-10-15 |
Not clear |
Jacob N Kisiolek, Victoria A Flores, Arjun Ramani, Blake Butler, James M Haughian, Laura K Stewar. Eight Weeks of Daily Cannabidiol Supplementation Improves Sleep Quality and Immune Cell Cytotoxicity. Nutrients. vol 15. issue 19. 2023-10-14. PMID:37836465. |
cannabidiol (cbd) is a non-intoxicating exogenous cannabinoid agonist derived from plants that, at high doses, has received fda approval as an anticonvulsant for epileptic seizures, and at low doses is marketed as a food-grade supplement for improved mental health, sleep quality, and immunological function. |
2023-10-14 |
2023-10-15 |
Not clear |
Elisa Teichmann, Elane Blessing, Burkhard Hin. Non-Psychoactive Phytocannabinoids Inhibit Inflammation-Related Changes of Human Coronary Artery Smooth Muscle and Endothelial Cells. Cells. vol 12. issue 19. 2023-10-13. PMID:37830604. |
in view of the cardioprotective effects of cannabinoids described in recent years, the present study investigated the impact of the non-psychoactive phytocannabinoids cannabidiol (cbd) and tetrahydrocannabivarin (thcv) on proliferation and migration of human coronary artery smooth muscle cells (hcasmc) and on inflammatory markers in human coronary artery endothelial cells (hcaec). |
2023-10-13 |
2023-10-15 |
human |
Peggy Arthur, Anil Kumar Kalvala, Sunil Kumar Surapaneni, Mandip Sachdeva Sing. Applications of Cannabinoids in Neuropathic Pain: An Updated Review. Critical reviews in therapeutic drug carrier systems. vol 41. issue 1. 2023-10-12. PMID:37824417. |
this review provides insights on the various preclinical and clinical therapeutic applications of cannabidiol (cbd), cannabigerol (cbg), and cannabinol (cbn) in various diseases and the ongoing clinical trials for the treatment of chronic and acute pain with cannabinoids. |
2023-10-12 |
2023-10-15 |
Not clear |