| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G C Haidet, T I Musch, G A Ordway, J H Mitchel. Exercise, dobutamine, and combined atropine, norepinephrine, and epinephrine compared. Journal of applied physiology (Bethesda, Md. : 1985). vol 58. issue 6. 1985-08-21. PMID:4008420. |
thus, in dogs, submaximal exercise, infusion of dobutamine, and infusion of a combination of atropine, norepinephrine, and epinephrine to evoke a given level of estimated myocardial o2 consumption produce similar increases in cardiac output, heart rate, and myocardial blood flow. |
1985-08-21 |
2023-08-11 |
Not clear |
| A L Hyman, H L Lippton, P J Kadowit. Autonomic regulation of the pulmonary circulation. Journal of cardiovascular pharmacology. vol 7 Suppl 3. 1985-07-30. PMID:2409403. |
the pulmonary vascular response to norepinephrine, dopamine, and dobutamine is the algebraic summation of activation of alpha- and beta-adrenoceptors. |
1985-07-30 |
2023-08-11 |
cat |
| H Ditter, F R Matthias, H G Lasc. Comparison of sympathomimetic amines with collagen, calcium ionophor and adenosine diphosphate in their effects on thromboxane formation of human platelet rich plasma. Folia haematologica (Leipzig, Germany : 1928). vol 111. issue 6. 1985-03-21. PMID:6083951. |
platelet rich plasma (prp) was stimulated by addition of epinephrine, norepinephrine, dopamine, dobutamine, adp, collagen or a 23187 in various concentrations. |
1985-03-21 |
2023-08-12 |
human |
| R N Pittman, R A Rabin, P B Molinof. Desensitization of beta-adrenergic receptor-coupled adenylate cyclase activity. Differences following exposure of cells to two full agonists. Biochemical pharmacology. vol 33. issue 22. 1984-12-27. PMID:6150707. |
decreases in gtp-stimulated adenylate cyclase activity were also observed following exposure of cells to epinephrine, cc-25, fenoterol, norepinephrine, terbutaline, or metaproterenol, but not following incubation of cells with dobutamine or salmefamol. |
1984-12-27 |
2023-08-12 |
Not clear |
| V M Sanders, A E Munso. Beta adrenoceptor mediation of the enhancing effect of norepinephrine on the murine primary antibody response in vitro. The Journal of pharmacology and experimental therapeutics. vol 230. issue 1. 1984-08-29. PMID:6086876. |
the magnitude and kinetics of the enhanced antibody response to norepinephrine alone, or to norepinephrine in the presence of phentolamine, were more closely mimicked with a beta-2 adrenoceptor agonist (terbutaline) than with a beta-1 adrenoceptor agonist (dobutamine). |
1984-08-29 |
2023-08-12 |
mouse |
| J A Armour, G A Klasse. Pressure and flow in epicardial coronary veins of the dog heart: responses to positive inotropism. Canadian journal of physiology and pharmacology. vol 62. issue 1. 1984-05-30. PMID:6713282. |
positive inotropic changes induced by stimulation of the right or left stellate ganglia or infusing isoproterenol, norepinephrine, or dobutamine significantly increased intramyocardial pressure, systolic epicardial coronary venous pressure, and systolic coronary venous flow. |
1984-05-30 |
2023-08-12 |
dog |
| H J Mersman. Adrenergic control of lipolysis in swine adipose tissue. Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology. vol 77. issue 1. 1984-03-29. PMID:6141880. |
catecholamines (epinephrine, norepinephrine and isoproterenol), the resorcinol containing beta 2-agonists (terbutaline, metaproterenol and fenoterol) and the beta 1-agonist, dobutamine were active. |
1984-03-29 |
2023-08-12 |
rat |
| C V Leier, D V Unverfert. Drugs five years later. Dobutamine. Annals of internal medicine. vol 99. issue 4. 1983-11-23. PMID:6625384. |
dobutamine has less vasopressor activity than norepinephrine and dopamine, and should not be the primary treatment in conditions characterized by marked hypotension and shock. |
1983-11-23 |
2023-08-12 |
Not clear |
| J E Shaffer, K U Mali. Enhancement of prostaglandin output during activation of beta-1 adrenoceptors in the isolated rabbit heart. The Journal of pharmacology and experimental therapeutics. vol 223. issue 3. 1983-01-27. PMID:6292398. |
the output of 6-keto pgf1 alpha, pge2 and pgf2 alpha was increased by electrical stimulation of the sympathetic nerves, norepinephrine, isoproterenol, dobutamine and angiotensin ii, but not by phenylephrine or isoetharine. |
1983-01-27 |
2023-08-12 |
rabbit |
| G A Rooke, E O Feig. Work as a correlate of canine left ventricular oxygen consumption, and the problem of catecholamine oxygen wasting. Circulation research. vol 50. issue 2. 1982-04-20. PMID:6120048. |
these indexes were prospectively applied to a second set of experiments in 11 closed-chest, anesthetized dogs given norepinephrine, isoproterenol, dobutamine, nembutal, and propranolol to alter myocardial contractility. |
1982-04-20 |
2023-08-12 |
Not clear |
| U Schulte-Sasse, W Hess, E Schweichel, J Tarnow, J B Brückne. [Systemic and coronary haemodynamic effects of dobutamine and norepinephrine during metabolic acidosis]. Der Anaesthesist. vol 30. issue 9. 1981-11-22. PMID:7283111. |
[systemic and coronary haemodynamic effects of dobutamine and norepinephrine during metabolic acidosis]. |
1981-11-22 |
2023-08-12 |
Not clear |
| U Schulte-Sasse, W Hess, E Schweichel, J Tarnow, J B Brückne. [Systemic and coronary haemodynamic effects of dobutamine and norepinephrine during metabolic acidosis]. Der Anaesthesist. vol 30. issue 9. 1981-11-22. PMID:7283111. |
the effects of clinical doses of dobutamine (5 microgram/kg x min) and norepinephrine (0.2 microgram/kg x min) on systemic haemodynamics and coronary circulation were studied during normal ph and during metabolic acidosis (ph 7.0) induced by hydrochloric acid in 9 anaesthetized closed chest dogs. |
1981-11-22 |
2023-08-12 |
Not clear |
| U Schulte-Sasse, W Hess, E Schweichel, J Tarnow, J B Brückne. [Systemic and coronary haemodynamic effects of dobutamine and norepinephrine during metabolic acidosis]. Der Anaesthesist. vol 30. issue 9. 1981-11-22. PMID:7283111. |
our results further demonstrated that a significant circulatory response to clinical doses of dobutamine and norepinephrine was still present during metabolic acidosis. |
1981-11-22 |
2023-08-12 |
Not clear |
| U Schulte-Sasse, W Hess, E Schweichel, J Tarnow, J B Brückne. [Systemic and coronary haemodynamic effects of dobutamine and norepinephrine during metabolic acidosis]. Der Anaesthesist. vol 30. issue 9. 1981-11-22. PMID:7283111. |
however, the increase in cardiac output, max dp/dt and mean arterial pressure after dobutamine was found to be significantly reduced at low ph-values, whereas the vasopressor response to norepinephrine was not affected. |
1981-11-22 |
2023-08-12 |
Not clear |
| R Gray, P K Shah, B Singh, C Conklin, J M Matlof. Low cardiac output states after open heart surgery. Comparative hemodynamic effects of dobutamine, dopamine, and norepinephrine plus phentolamine. Chest. vol 80. issue 1. 1981-09-15. PMID:7249704. |
comparative hemodynamic effects of dobutamine, dopamine, and norepinephrine plus phentolamine. |
1981-09-15 |
2023-08-12 |
Not clear |
| R Gray, P K Shah, B Singh, C Conklin, J M Matlof. Low cardiac output states after open heart surgery. Comparative hemodynamic effects of dobutamine, dopamine, and norepinephrine plus phentolamine. Chest. vol 80. issue 1. 1981-09-15. PMID:7249704. |
for dobutamine and dopamine the doses were 2.5, 5.0 and 10.0 microgram/kg/min; for norepinephrine, 0.02, 0.05 and 0.10 microgram/kg/min with phentolamine in the ratio of 1 (norepinephrine) to 2.5 (phentolamine). |
1981-09-15 |
2023-08-12 |
Not clear |
| M T Marquez, L E de Mikulic, P Aramendí. Differential beta-adrenergic sensitivity of atrial tissue assessed by chronotropic and inotropic responses to several sympathomimetic amines. Acta physiologica latino americana. vol 28. issue 4-5. 1981-06-23. PMID:233499. |
the relative inotropic and chronotropic activity of epinephrine, norepinephrine, isoproterenol, dopamine, dobutamine and ethylephrine was studied on isolated rat atria at 31 c. dose-response curves were expressed as a percentage of the maximum response. |
1981-06-23 |
2023-08-11 |
rat |
| T P Kenaki. An in vitro quantitative analysis of the alpha adrenoceptor partial agonist activity of dobutamine and its relevance to inotropic selectivity. The Journal of pharmacology and experimental therapeutics. vol 216. issue 2. 1981-04-21. PMID:6109772. |
therefore, dobutamine satisfied criteria for a partial agonist of alpha adrenoceptors having an affinity for alpha adrenoceptors 25 times that of norepinephrine (pka = 6.3) in this tissue. |
1981-04-21 |
2023-08-12 |
rat |
| T P Kenaki. An in vitro quantitative analysis of the alpha adrenoceptor partial agonist activity of dobutamine and its relevance to inotropic selectivity. The Journal of pharmacology and experimental therapeutics. vol 216. issue 2. 1981-04-21. PMID:6109772. |
an estimate of the relative efficacy of dobutamine showed one-fortieth the the efficacy of norepinephrine at the alpha adrenoceptors. |
1981-04-21 |
2023-08-12 |
rat |
| J H Fleisch, S M Spaeth. Vasodilation and aging evaluated in the isolated perfused rat mesenteric vascular bed: preliminary observations on the vascular pharmacology of dobutamine. Journal of cardiovascular pharmacology. vol 3. issue 1. 1981-02-26. PMID:6160348. |
a comparison of the action of isoproterenol and dobutamine revealed that isoproterenol stimulated vascular beta-receptors, whereas dobutamine relaxed the mesentery by antagonizing the tone produced by norepinephrine. |
1981-02-26 |
2023-08-12 |
rat |