| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Andrew D Stewart, Sandrine C Millasseau, Mark T Kearney, James M Ritter, Philip J Chowienczy. Effects of inhibition of basal nitric oxide synthesis on carotid-femoral pulse wave velocity and augmentation index in humans. Hypertension (Dallas, Tex. : 1979). vol 42. issue 5. 2003-12-04. PMID:12975386. |
healthy men (32 to 48 years old, n=8) were studied on 4 occasions and received, in random order, vehicle, l-nmma (3 mg x kg(-1) by intravenous bolus followed by 3 mg x kg(-1) x h(-1)), norepinephrine (50 ng x kg(-1) x min(-1)), and dobutamine (2.5 to 10 microg x kg(-1) x min(-1)), each for 30 minutes. |
2003-12-04 |
2023-08-12 |
Not clear |
| Andrew D Stewart, Sandrine C Millasseau, Mark T Kearney, James M Ritter, Philip J Chowienczy. Effects of inhibition of basal nitric oxide synthesis on carotid-femoral pulse wave velocity and augmentation index in humans. Hypertension (Dallas, Tex. : 1979). vol 42. issue 5. 2003-12-04. PMID:12975386. |
l-nmma and norepinephrine increased aix, but dobutamine decreased aix (p<0.01 vs norepinephrine and l-nmma). |
2003-12-04 |
2023-08-12 |
Not clear |
| I Germanakis, C Bender, R Hentschel, K Braun, S Dittrich, D Kececiogl. Hypercontractile heart failure caused by catecholamine therapy in premature neonates. Acta paediatrica (Oslo, Norway : 1992). vol 92. issue 7. 2003-12-01. PMID:12892164. |
epinephrine and dobutamine were stopped, and norepinephrine (noradrenaline) was successfully used to control the hypotension. |
2003-12-01 |
2023-08-12 |
Not clear |
| Kohji Mori, Emi Ozaki, Bo Zhang, Lihua Yang, Akiko Yokoyama, Ikuko Takeda, Nobuji Maeda, Masahiro Sakanaka, Junya Tanak. Effects of norepinephrine on rat cultured microglial cells that express alpha1, alpha2, beta1 and beta2 adrenergic receptors. Neuropharmacology. vol 43. issue 6. 2003-06-24. PMID:12423672. |
norepinephrine, an alpha1 agonist phenylephrine, a beta1 agonist dobutamine and terbutaline suppressed the expressions of mrnas encoding pro-inflammatory cytokines, interleukin-6 and tumor necrosis factor alpha. |
2003-06-24 |
2023-08-12 |
rat |
| Kohji Mori, Emi Ozaki, Bo Zhang, Lihua Yang, Akiko Yokoyama, Ikuko Takeda, Nobuji Maeda, Masahiro Sakanaka, Junya Tanak. Effects of norepinephrine on rat cultured microglial cells that express alpha1, alpha2, beta1 and beta2 adrenergic receptors. Neuropharmacology. vol 43. issue 6. 2003-06-24. PMID:12423672. |
release of tumor necrosis factor alpha and nitric oxide was suppressed by norepinephrine, phenylephrine, dobutamine and terbutaline. |
2003-06-24 |
2023-08-12 |
rat |
| Kohji Mori, Emi Ozaki, Bo Zhang, Lihua Yang, Akiko Yokoyama, Ikuko Takeda, Nobuji Maeda, Masahiro Sakanaka, Junya Tanak. Effects of norepinephrine on rat cultured microglial cells that express alpha1, alpha2, beta1 and beta2 adrenergic receptors. Neuropharmacology. vol 43. issue 6. 2003-06-24. PMID:12423672. |
an alpha2 agonist clonidine and dobutamine upregulated the expression of mrna encoding catechol-o-methyl transferase, an important enzyme to degrade norepinephrine. |
2003-06-24 |
2023-08-12 |
rat |
| Kohji Mori, Emi Ozaki, Bo Zhang, Lihua Yang, Akiko Yokoyama, Ikuko Takeda, Nobuji Maeda, Masahiro Sakanaka, Junya Tanak. Effects of norepinephrine on rat cultured microglial cells that express alpha1, alpha2, beta1 and beta2 adrenergic receptors. Neuropharmacology. vol 43. issue 6. 2003-06-24. PMID:12423672. |
norepinephrine, dobutamine and terbutaline upregulated the expressions of mrna encoding 3-phospshoglycerate dehydrogenase, an essential enzyme for synthesis of l-serine and glycine, which are amino acids necessary for neuronal survival. |
2003-06-24 |
2023-08-12 |
rat |
| Rangaswamy Nagmani, David S Pasco, Ruben D Salas, Dennis R Felle. Evaluation of beta-adrenergic receptor subtypes in the human prostate cancer cell line-LNCaP. Biochemical pharmacology. vol 65. issue 9. 2003-06-16. PMID:12732361. |
the rank order of potency for catecholamines and known beta-ar agonists was terbutaline(3.31 nm)>isoproterenol(8.31 nm)> or =fenoterol(15 nm)=epinephrine(16.2 nm)>norepinephrine(77.5 nm)>brl-37344 [(r(*),r(*))-(+/-)4-[2-[(2-(3-chlorophenyl)-2-hydroxyethyl)amino]propyl]phenoxy acetic acid, sodium salt] (1000 nm)>dobutamine(1770 nm)>cgp12177 (4-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]-1,3-dihydro-2h-benzimidazole-2-one hydrochloride) (inactive). |
2003-06-16 |
2023-08-12 |
human |
| Qinghua Sun, Zizhi Tu, Suzana Lobo, George Dimopoulos, Nathalie Nagy, Peter Rogiers, Daniel De Backer, Jean-Louis Vincen. Optimal adrenergic support in septic shock due to peritonitis. Anesthesiology. vol 98. issue 4. 2003-04-29. PMID:12657850. |
the authors evaluated optimal adrenergic support using norepinephrine, dopamine, and dobutamine in a clinically relevant model of septic shock. |
2003-04-29 |
2023-08-12 |
Not clear |
| Esko Ruokonen, Ilkka Parviainen, Ari Uusar. Treatment of impaired perfusion in septic shock. Annals of medicine. vol 34. issue 7-8. 2003-04-28. PMID:12553499. |
the drug of choice for low vascular resistance is norepinephrine, while insufficient myocardial contractility is commonly treated with dobutamine. |
2003-04-28 |
2023-08-12 |
Not clear |
| Primrose P Freestone, Peter H Williams, Richard D Haigh, Anthony F Maggs, Christopher P Neal, Mark Lyt. Growth stimulation of intestinal commensal Escherichia coli by catecholamines: a possible contributory factor in trauma-induced sepsis. Shock (Augusta, Ga.). vol 18. issue 5. 2003-04-25. PMID:12412628. |
the synthetic catecholamine inotropes dobutamine and isoprenaline, as well as norepinephrine metabolites that retained the catechol structure were also active, whereas norepinephrine metabolites in which the catechol moiety had been modified were not. |
2003-04-25 |
2023-08-12 |
human |
| M A Weigand, H J Bardenheuer, B W Böttige. [Clinical management of patients with sepsis]. Der Anaesthesist. vol 52. issue 1. 2003-04-01. PMID:12577161. |
norepinephrine is the vasopressor of choice and dobutamine the preferred inotropic agent. |
2003-04-01 |
2023-08-12 |
Not clear |
| Vera Junker, Andreas Becker, Ricarda Hühne, Marat Zembatov, Alexander Ravati, Carsten Culmsee, Josef Krieglstei. Stimulation of beta-adrenoceptors activates astrocytes and provides neuroprotection. European journal of pharmacology. vol 446. issue 1-3. 2003-01-08. PMID:12098582. |
however, similar morphological changes in astrocytes were also observed after stimulation of beta(1)-adrenoceptors by dobutamine (1-10 microm) and norepinephrine (1-10 microm). |
2003-01-08 |
2023-08-12 |
mouse |
| Tohru Takahashi, Koji Kohno, Mitsuo Kashida, Toyohiko Morita, Kiyoshi Saito, Akiko Kamei, Yujong Seo, Itta Kawamura, Taro Kojima, Yutaka Seki, Kan Saito, Kenta Kumagai, Kunihiko Ohno, Yuriko Tanaka, Yoshinori Itaoka, Osamu Okazaki, Kazuhide Izumo, Sosuke Kimura, Nobuharu Akatsuka, Yoshio Yazak. A survival case of acute mitral regurgitation and cardiogenic shock caused by subtotal occlusion of the first diagonal branch. Circulation journal : official journal of the Japanese Circulation Society. vol 66. issue 6. 2002-12-20. PMID:12074285. |
the patient was initially treated with high-dose dopamine, dobutamine and norepinephrine. |
2002-12-20 |
2023-08-12 |
Not clear |
| Philippe Seguin, Eric Bellissant, Yves Le Tulzo, Bruno Laviolle, Yvon Lessard, Rémy Thomas, Yannick Mallédan. Effects of epinephrine compared with the combination of dobutamine and norepinephrine on gastric perfusion in septic shock. Clinical pharmacology and therapeutics. vol 71. issue 5. 2002-06-17. PMID:12011824. |
effects of epinephrine compared with the combination of dobutamine and norepinephrine on gastric perfusion in septic shock. |
2002-06-17 |
2023-08-12 |
Not clear |
| Philippe Seguin, Eric Bellissant, Yves Le Tulzo, Bruno Laviolle, Yvon Lessard, Rémy Thomas, Yannick Mallédan. Effects of epinephrine compared with the combination of dobutamine and norepinephrine on gastric perfusion in septic shock. Clinical pharmacology and therapeutics. vol 71. issue 5. 2002-06-17. PMID:12011824. |
the aim of the study was to compare epinephrine with the combination of dobutamine and norepinephrine on gastric perfusion in patients with septic shock. |
2002-06-17 |
2023-08-12 |
Not clear |
| S G Sakka, K Reinhart, K Wegscheider, A Meier-Hellman. Variability of splanchnic blood flow in patients with sepsis. Intensive care medicine. vol 27. issue 8. 2001-11-01. PMID:11511940. |
we assessed the variability of splanchnic blood flow during stable global hemodynamics in eight patients with sepsis requiring treatment with dobutamine and/or norepinephrine. |
2001-11-01 |
2023-08-12 |
Not clear |
| O Picker, T W Scheere. [Coupling of cardiac output or systemic O2 transport and metabolism during catecholamine therapy]. Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS. vol 36. issue 2. 2001-04-26. PMID:11269019. |
during physiological conditions, the synthetic agents dobutamine and dopexamine primarily increase co, whereas the endogenous ones epinephrine and particularly norepinephrine increase both co and vo2 to about the same extent. |
2001-04-26 |
2023-08-12 |
Not clear |
| H Naruse, T Arii, T Kondo, M Ohnishi, T Sakaki, K Takahashi, M Masai, M Ohyanagi, T Iwasaki, M Fukuch. Relation between myocardial response to dobutamine stress and sympathetic nerve activation in patients with idiopathic dilated cardiomyopathy: a comparison of 123I-MIBG scintigraphic and echocardiographic data. Annals of nuclear medicine. vol 14. issue 6. 2001-04-12. PMID:11210095. |
this study was conducted to demonstrate the relation between myocardial response to dobutamine stress and sympathetic nerve release of norepinephrine in the failing heart. |
2001-04-12 |
2023-08-12 |
Not clear |
| H Naruse, T Arii, T Kondo, M Ohnishi, T Sakaki, K Takahashi, M Masai, M Ohyanagi, T Iwasaki, M Fukuch. Relation between myocardial response to dobutamine stress and sympathetic nerve activation in patients with idiopathic dilated cardiomyopathy: a comparison of 123I-MIBG scintigraphic and echocardiographic data. Annals of nuclear medicine. vol 14. issue 6. 2001-04-12. PMID:11210095. |
in 12 patients with heart failure due to idiopathic dilated cardiomyopathy, the myocardial effects of dobutamine stress were evaluated by low-dose dobutamine stress echocardiography: and sympathetic nerve function was evaluated by scintigraphic imaging with iodine-123 [123i] meta-iodobenzylguanidine (mibg), an analogue of norepinephrine. |
2001-04-12 |
2023-08-12 |
Not clear |