| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Anna Sarnowsk. Application of organotypic hippocampal culture for study of selective neuronal death. Folia neuropathologica. vol 40. issue 2. 2002-10-22. PMID:12230254. |
both clinical and experimental studies confirm that the hippocampus, and particularly its ca1 sub-field, is exceptionally vulnerable to ischaemic and other brain injuries. |
2002-10-22 |
2023-08-12 |
rat |
| Raffaella Carpenedo, Elena Meli, Fiamma Peruginelli, Domenico E Pellegrini-Giampietro, Flavio Moron. Kynurenine 3-mono-oxygenase inhibitors attenuate post-ischemic neuronal death in organotypic hippocampal slice cultures. Journal of neurochemistry. vol 82. issue 6. 2002-10-22. PMID:12354294. |
our results suggest that kmo inhibitors reduce the neuronal death found in the ca1 region of organotypic hippocampal slices exposed to 30 min of ogd by decreasing the local synthesis of 3-hk and quin. |
2002-10-22 |
2023-08-12 |
Not clear |
| William M Humphrey, HongXin Dong, Cynthia A Csernansky, John G Csernansk. Immediate and delayed hippocampal neuronal loss induced by kainic acid during early postnatal development in the rat. Brain research. Developmental brain research. vol 137. issue 1. 2002-10-16. PMID:12128249. |
the appearance of tunel-positive hippocampal neurons accompanied the delayed neuronal loss in both ca3 and ca1 and electron micrographs confirmed that neurons in these subfields were undergoing apoptosis. |
2002-10-16 |
2023-08-12 |
rat |
| Johannes Graulich, Ulrike Hoffmann, Rolf F Maier, Karsten Ruscher, Jörn K Pomper, Hae-Kyung Ko, Siegrun Gabriel, Michael Obladen, Uwe Heineman. Acute neuronal injury after hypoxia is influenced by the reoxygenation mode in juvenile hippocampal slice cultures. Brain research. Developmental brain research. vol 137. issue 1. 2002-10-16. PMID:12128252. |
pi fluorescence increased after hypoxia in all principal cell layers of the hippocampus but again showed a larger enhancement after hyperoxic reoxygenation as compared to normoxic reoxygenation (e.g., by a factor of 3.9 vs. 1.7 for ca1 and 120 min of hypoxia). |
2002-10-16 |
2023-08-12 |
rat |
| Angela M Thompson, Blake A Gosnell, John J Wagne. Enhancement of long-term potentiation in the rat hippocampus following cocaine exposure. Neuropharmacology. vol 42. issue 8. 2002-10-11. PMID:12128005. |
the effect of cocaine on one prominent cellular mechanism for learning/memory, long-term potentiation (ltp), was assessed in the ca1 region of the rat hippocampus. |
2002-10-11 |
2023-08-12 |
human |
| Abdulmonem Al-Hayani, Stephen N Davie. Effect of cannabinoids on synaptic transmission in the rat hippocampal slice is temperature-dependent. European journal of pharmacology. vol 442. issue 1-2. 2002-10-08. PMID:12020681. |
we have previously reported that the synthetic cannabinoid r-(+)-[2,3-dihydro-5-methyl-3-[(morpholinyl)methyl]pyrrolo[1,2,3-de]-1,4-benzoxazin-yl]-(1-naphthalenyl)methanone mesylate (win55,212-2) causes a selective inhibition of paired pulse depression of population spikes recorded from the ca1 region of rat hippocampal slices maintained at 28-30 degrees c. we now show that this effect is highly temperature-dependent and that win55,212-2 actually increases paired pulse depression of population spikes recorded from slices maintained at 35 degrees c. this temperature dependence was found to correlate with the effects of the known gamma-amino butyric acid (gaba)-uptake inhibitors, nipecotic acid and guvacine, which were without effect at 28-30 degrees c, but increased paired pulse depression at 35 degrees c. the results show that the effects of cannabinoids on synaptic transmission in the hippocampal slice are highly temperature-dependent and it is suggested that this is due to the presence of increased gaba uptake at higher temperatures. |
2002-10-08 |
2023-08-12 |
rat |
| I V Kudryashov. Responses of hippocampal neurons at different stages of acquisition of conditioned reflex avoidance in rats. Neuroscience and behavioral physiology. vol 32. issue 2. 2002-10-01. PMID:11942690. |
associative learning (presentation of combinations of conditioned and unconditioned stimuli) was accompanied by gradual increases in the amplitude of the population spike in hippocampal field ca1. |
2002-10-01 |
2023-08-12 |
rat |
| Michael I Daw, Zuner A Bortolotto, Emilia Saulle, Shahid Zaman, Graham L Collingridge, John T R Isaa. Phosphatidylinositol 3 kinase regulates synapse specificity of hippocampal long-term depression. Nature neuroscience. vol 5. issue 9. 2002-09-27. PMID:12161757. |
to investigate the role of phosphatidylinositol 3 kinase (pi3 kinase) in hippocampal synaptic plasticity, we used whole-cell patch clamp recordings from rat ca1 neurons to determine the effects of pi3 kinase inhibitors on long-term depression (ltd). |
2002-09-27 |
2023-08-12 |
rat |
| Alfredo Feria-Velasco, Alma Rosa del Angel, Ignacio Gonzalez-Burgo. Modification of dendritic development. Progress in brain research. vol 136. 2002-09-19. PMID:12143377. |
by using a chronic try restriction model in rats, we studied their place learning ability in correlation with the dendritic spine density of pyramidal neurons in field ca1 of the hippocampus during postnatal development. |
2002-09-19 |
2023-08-12 |
rat |
| U Coumis, C H Davie. The effects of galanin on long-term synaptic plasticity in the CA1 area of rodent hippocampus. Neuroscience. vol 112. issue 1. 2002-09-06. PMID:12044482. |
the effects of galanin on long-term synaptic plasticity in the ca1 area of rodent hippocampus. |
2002-09-06 |
2023-08-12 |
mouse |
| Guido C Faas, Hita Adwanikar, Robert W Gereau, Peter Sagga. Modulation of presynaptic calcium transients by metabotropic glutamate receptor activation: a differential role in acute depression of synaptic transmission and long-term depression. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 16. 2002-09-04. PMID:12177186. |
activation of group i metabotropic glutamate receptors (mglurs) can induce acute depression of excitatory synaptic transmission and long-term depression (ltd) in area ca1 of the rat hippocampus. |
2002-09-04 |
2023-08-12 |
rat |
| L V Lopes, R A Cunha, B Kull, B B Fredholm, J A Ribeir. Adenosine A(2A) receptor facilitation of hippocampal synaptic transmission is dependent on tonic A(1) receptor inhibition. Neuroscience. vol 112. issue 2. 2002-08-29. PMID:12044450. |
the a(2a) receptor agonist, cgs 21680 (10 nm), facilitated synaptic transmission in the ca1 area of rat hippocampal slices (by 14%), independent of whether or not gabaergic transmission was blocked by the gaba(a) and gaba(b) receptor antagonists, picrotoxin (50 microm) and cgp 55845 (1 microm), respectively. |
2002-08-29 |
2023-08-12 |
rat |
| Xiao-yan Zhang, Ai-Ping Liu, Di-Yun Ruan, Jin Li. Effect of developmental lead exposure on the expression of specific NMDA receptor subunit mRNAs in the hippocampus of neonatal rats by digoxigenin-labeled in situ hybridization histochemistry. Neurotoxicology and teratology. vol 24. issue 2. 2002-08-27. PMID:11943503. |
in pb-exposed rats, hippocampal nr1-2a mrna levels were significantly increased in ca1, ca4 and dg subfields at 15 days of age and ca4 and dg subfields at 20 days of age. |
2002-08-27 |
2023-08-12 |
rat |
| Xiao-yan Zhang, Ai-Ping Liu, Di-Yun Ruan, Jin Li. Effect of developmental lead exposure on the expression of specific NMDA receptor subunit mRNAs in the hippocampus of neonatal rats by digoxigenin-labeled in situ hybridization histochemistry. Neurotoxicology and teratology. vol 24. issue 2. 2002-08-27. PMID:11943503. |
the lead (pb) exposure resulted in a significant increase of nr2d mrna levels in ca1, ca2, ca4 and dg hippocampal subfields at 20 days of age. |
2002-08-27 |
2023-08-12 |
rat |
| Xiao-yan Zhang, Ai-Ping Liu, Di-Yun Ruan, Jin Li. Effect of developmental lead exposure on the expression of specific NMDA receptor subunit mRNAs in the hippocampus of neonatal rats by digoxigenin-labeled in situ hybridization histochemistry. Neurotoxicology and teratology. vol 24. issue 2. 2002-08-27. PMID:11943503. |
hippocampal nr2a mrna levels were significantly decreased in ca1, ca2, ca3 and dg subfields from 15-day-old pb-exposed rats and ca1, ca3 and dg subfields from 20-day-old pb-exposed rats. |
2002-08-27 |
2023-08-12 |
rat |
| Xiao-yan Zhang, Ai-Ping Liu, Di-Yun Ruan, Jin Li. Effect of developmental lead exposure on the expression of specific NMDA receptor subunit mRNAs in the hippocampus of neonatal rats by digoxigenin-labeled in situ hybridization histochemistry. Neurotoxicology and teratology. vol 24. issue 2. 2002-08-27. PMID:11943503. |
hippocampal nr3a mrna levels were also significantly decreased in ca1, ca4 and dg subfields at 15 days of age and ca1 and dg subfields at 20 days of age in pb-exposed rats. |
2002-08-27 |
2023-08-12 |
rat |
| Selma K Kaasinen, Gundars Goldsteins, Leena Alhonen, Juhani Jänne, Jari Koistinah. Induction and activation of protein kinase C delta in hippocampus and cortex after kainic acid treatment. Experimental neurology. vol 176. issue 1. 2002-08-16. PMID:12093097. |
the expression of pkc delta mrna was strikingly upregulated (13-fold) in the cortex and the ca1 and ca3 hippocampal regions on 1 day after kainate administration, whereas pkc zeta mrna was only moderately increased (about 100%) in these three brain regions on day 2 following the drug. |
2002-08-16 |
2023-08-12 |
rat |
| E van Riel, O C Meijer, A H Veenema, M Joël. Hippocampal serotonin responses in short and long attack latency mice. Journal of neuroendocrinology. vol 14. issue 3. 2002-08-14. PMID:11999724. |
we tested whether the functional responses of ca1 hippocampal cells to serotonin are also reduced in long attack latency mice. |
2002-08-14 |
2023-08-12 |
mouse |
| Stephen E Alves, Elena Hoskin, Susan J Lee, Wayne G Brake, Deveroux Ferguson, Victoria Luine, Patrick B Allen, Paul Greengard, Bruce S McEwe. Serotonin mediates CA1 spine density but is not crucial for ovarian steroid regulation of synaptic plasticity in the adult rat dorsal hippocampus. Synapse (New York, N.Y.). vol 45. issue 2. 2002-08-08. PMID:12112407. |
serotonin mediates ca1 spine density but is not crucial for ovarian steroid regulation of synaptic plasticity in the adult rat dorsal hippocampus. |
2002-08-08 |
2023-08-12 |
rat |
| Stephen E Alves, Elena Hoskin, Susan J Lee, Wayne G Brake, Deveroux Ferguson, Victoria Luine, Patrick B Allen, Paul Greengard, Bruce S McEwe. Serotonin mediates CA1 spine density but is not crucial for ovarian steroid regulation of synaptic plasticity in the adult rat dorsal hippocampus. Synapse (New York, N.Y.). vol 45. issue 2. 2002-08-08. PMID:12112407. |
we sought to determine whether 5-ht is involved in maintaining ca1 spine density and/or in steroid regulation of synaptic plasticity in dorsal hippocampus. |
2002-08-08 |
2023-08-12 |
rat |