Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
O Ghribi, L Lapierre, M Girard, M Ohayon, J Nalbantoglu, G Massicott. Hypoxia-induced loss of synaptic transmission is exacerbated in hippocampal slices of transgenic mice expressing C-terminal fragments of Alzheimer amyloid precursor protein. Hippocampus. vol 9. issue 3. 1999-10-19. PMID:10401636. |
recovery of synaptic transmission was monitored in area ca1 of perfused hippocampal slices prepared from both control and tg mice. |
1999-10-19 |
2023-08-12 |
mouse |
A M Rao, J F Hatcher, M S Kindy, R J Dempse. Arachidonic acid and leukotriene C4: role in transient cerebral ischemia of gerbils. Neurochemical research. vol 24. issue 10. 1999-10-18. PMID:10492517. |
increased lipid peroxidation due to aa metabolism was observed between 2-6 h. bbb dysfunction occurred at 6 h. significant edema developed at 1 and 2 d after ischemia and reached maximum at 3 d. ischemia resulted in approximately 80% neuronal death in the ca1 hippocampal region. |
1999-10-18 |
2023-08-12 |
Not clear |
M H Won, T C Kang, G S Jeon, J C Lee, D Y Kim, E M Choi, K H Lee, C D Choi, M H Chung, S S Ch. Immunohistochemical detection of oxidative DNA damage induced by ischemia-reperfusion insults in gerbil hippocampus in vivo. Brain research. vol 836. issue 1-2. 1999-10-15. PMID:10415406. |
the 8-ohdg levels in the hippocampus increased significantly (about fourfold) after 3 h of reperfusion and remained significantly (p<0.01) elevated for at least 12 h. at 4 days after ischemia, 8-ohdg levels in the ca2 and ca3 areas decreased to levels of the sham without neuronal loss, while disappearance of 8-ohdg immunoreactivity in the ca1 coincided with neuronal death in this area. |
1999-10-15 |
2023-08-12 |
Not clear |
J Liu, K Fukunaga, H Yamamoto, K Nishi, E Miyamot. Differential roles of Ca(2+)/calmodulin-dependent protein kinase II and mitogen-activated protein kinase activation in hippocampal long-term potentiation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 19. 1999-10-14. PMID:10493730. |
the roles of ca(2+)/calmodulin-dependent protein kinase ii (cam kinase ii) and mitogen-activated protein kinase (mapk) in long-term potentiation (ltp) were investigated in the ca1 area of hippocampal slices, using electrophysiological and biochemical approaches. |
1999-10-14 |
2023-08-12 |
Not clear |
M Carli, S Silva, C Balducci, R Samani. WAY 100635, a 5-HT1A receptor antagonist, prevents the impairment of spatial learning caused by blockade of hippocampal NMDA receptors. Neuropharmacology. vol 38. issue 8. 1999-10-12. PMID:10462129. |
cpp, 3 and 10 ng/microl, administered bilaterally into the ca1 region of the dorsal hippocampus 10 min before each training session, dose-dependently reduced choice accuracy in the two-platform spatial discrimination task with little or no effect on choice latency and errors of omission. |
1999-10-12 |
2023-08-12 |
Not clear |
Y Yoneda, K Ogita, Y Azuma, N Kuramoto, T Manabe, T Kitayam. Predominant expression of nuclear activator protein-1 complex with DNA binding activity following systemic administration of N-methyl-D-aspartate in dentate granule cells of murine hippocampus. Neuroscience. vol 93. issue 1. 1999-10-08. PMID:10430467. |
resulted in preferential but transient expression of the transcription factor activator protein-1 in the granule cell layers of the dentate gyrus in the murine hippocampus by maximally 700% 1 h later, without markedly affecting that in the pyramidal cell layers of the ca1 and ca3 subfields for 4 h. the potentiation was completely prevented by prior administration of the n-methyl-d-aspartate channel blocker dizocilpine at 10 mglkg. |
1999-10-08 |
2023-08-12 |
Not clear |
F Zheng, S Khann. Hippocampal field CA1 interneuronal nociceptive responses: modulation by medial septal region and morphine. Neuroscience. vol 93. issue 1. 1999-10-08. PMID:10430469. |
a majority (24/32) of the extracellularly recorded dorsal hippocampus field ca1 putative gabaergic interneurons were excited in conjunction with theta activation on formalin injection (5%, 0.05 ml, s.c. into right hind-paw) in urethane (1.0 g/kg, i.p. |
1999-10-08 |
2023-08-12 |
rat |
M J Herguido, F Carceller, J M Roda, C Avendañ. Hippocampal cell loss in transient global cerebral ischemia in rats: a critical assessment. Neuroscience. vol 93. issue 1. 1999-10-08. PMID:10430471. |
the neural damage inflicted by this intervention is often assessed by measuring pyramidal cell loss in the ca1 hippocampal field. |
1999-10-08 |
2023-08-12 |
rat |
P Dahlqvist, L Zhao, I M Johansson, B Mattsson, B B Johansson, J R Seckl, T Olsso. Environmental enrichment alters nerve growth factor-induced gene A and glucocorticoid receptor messenger RNA expression after middle cerebral artery occlusion in rats. Neuroscience. vol 93. issue 2. 1999-10-07. PMID:10465436. |
stroke induced a decrease in nerve growth factor-induced gene a messenger rna expression in cortical areas outside the ischemic lesion and in the ca1 subregion of the hippocampus two to three days after ischemia. |
1999-10-07 |
2023-08-12 |
rat |
I T Bayazitov, A M Kleshchevniko. Selective suppression of forward and recurrent "rapid" inhibition by local application of picrotoxin in area CA1 of rat hippocampal slices. Neuroscience and behavioral physiology. vol 29. issue 2. 1999-10-04. PMID:10432497. |
living slices of rat hippocampus were used to study the possibility of suppressing forward and recurrent "rapid" inhibition in area ca1 by local application of picrotoxin, an antagonist of ionotropic gamma-aminobutyric acid (gabaa) receptors. |
1999-10-04 |
2023-08-12 |
rat |
M Esclapez, C R House. Up-regulation of GAD65 and GAD67 in remaining hippocampal GABA neurons in a model of temporal lobe epilepsy. The Journal of comparative neurology. vol 412. issue 3. 1999-09-30. PMID:10441235. |
in the pilocarpine model of chronic limbic seizures, subpopulations of glutamic acid decarboxylase (gad)-containing neurons within the hilus of the dentate gyrus and stratum oriens of the ca1 hippocampal region are vulnerable to seizure-induced damage. |
1999-09-30 |
2023-08-12 |
Not clear |
I Reinprecht, A Gschanes, M Windisch, G Fachbac. Two peptidergic drugs increase the synaptophysin immunoreactivity in brains of 24-month-old rats. The Histochemical journal. vol 31. issue 6. 1999-09-29. PMID:10462225. |
our results clearly showed that the rats benefit from the administration of both drugs, showing an enhancement in the number of synaptophysin-immunostained presynaptic terminals in the entorhinal cortex, the dentate gyrus, and also in the hippocampal subfields ca1, ca2, ca3 stratum lucidum and ca3 stratum radiatum. |
1999-09-29 |
2023-08-12 |
rat |
T J O'Dell, E R Kande. Low-frequency stimulation erases LTP through an NMDA receptor-mediated activation of protein phosphatases. Learning & memory (Cold Spring Harbor, N.Y.). vol 1. issue 2. 1999-09-29. PMID:10467591. |
furthermore, the protein phosphatase inhibitors okadaic acid and calyculin a blocked both depotentiation and the ability of 5 hz stimulation to inhibit subsequent ltp, suggesting that protein phosphatases are involved in the ability of 5 hz stimulation to modulate synaptic plasticity in the ca1 region of the hippocampus. |
1999-09-29 |
2023-08-12 |
Not clear |
I Niespodziany, H Klitgaard, D G Marginean. Chronic electrode implantation entails epileptiform field potentials in rat hippocampal slices, similarly to amygdala kindling. Epilepsy research. vol 36. issue 1. 1999-09-28. PMID:10463852. |
evoked field potentials were recorded in the ca3, ca1 and dentate gyrus (dg) of hippocampal slices from amygdala kindled, non-stimulated amygdala electrode-implanted, and non-implanted age-matched rats to evaluate the consequences on hippocampal neuronal networks of kindling stimulation versus electrode implantation. |
1999-09-28 |
2023-08-12 |
rat |
W M Gao, B Wang, X Y Zho. Effects of prenatal low-dose beta radiation from tritiated water on learning and memory in rats and their possible mechanisms. Radiation research. vol 152. issue 3. 1999-09-23. PMID:10453087. |
the number of pyramidal cells (in areas ca1, ca2, ca3 and ca4) and neurons in the hippocampus of the offspring was also measured. |
1999-09-23 |
2023-08-12 |
rat |
C M Atkins, J D Sweat. Reactive oxygen species mediate activity-dependent neuron-glia signaling in output fibers of the hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 17. 1999-09-23. PMID:10460230. |
high-frequency, but not low-frequency, action potential firing in myelinated ca1 axons of the hippocampus resulted in increased phosphorylation of the oligodendrocyte-specific protein myelin basic protein (mbp). |
1999-09-23 |
2023-08-12 |
Not clear |
C M Atkins, J D Sweat. Reactive oxygen species mediate activity-dependent neuron-glia signaling in output fibers of the hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 17. 1999-09-23. PMID:10460230. |
these results indicate that, during periods of increased neuronal activity in area ca1 of the hippocampus, reactive oxygen and nitrogen species are generated, which diffuse to neighboring oligodendrocytes and result in post-translational modifications of mbp, a key structural protein in myelin. |
1999-09-23 |
2023-08-12 |
Not clear |
J L Swanson-Park, C M Coussens, S E Mason-Parker, C R Raymond, E L Hargreaves, M Dragunow, A S Cohen, W C Abraha. A double dissociation within the hippocampus of dopamine D1/D5 receptor and beta-adrenergic receptor contributions to the persistence of long-term potentiation. Neuroscience. vol 92. issue 2. 1999-09-17. PMID:10408599. |
we compared the effects of the d1/d5 receptor antagonist sch-23390 with the beta-adrenergic receptor antagonist propranolol on the persistence of long-term potentiation in the ca1 and dentate gyrus subregions of the hippocampus. |
1999-09-17 |
2023-08-12 |
Not clear |
D K Selig, M R Segal, D Liao, R C Malenka, R Malinow, R A Nicoll, J E Lisma. Examination of the role of cGMP in long-term potentiation in the CA1 region of the hippocampus. Learning & memory (Cold Spring Harbor, N.Y.). vol 3. issue 1. 1999-09-09. PMID:10456075. |
the mechanisms underlying the generation of nmda receptor-dependent ltp in the ca1 region of the hippocampus continue to receive a great deal of attention because of the postulated importance of ltp as a synaptic mechanism for learning and memory. |
1999-09-09 |
2023-08-12 |
Not clear |
C M Coussens, T J Teyle. Long-term potentiation induces synaptic plasticity at nontetanized adjacent synapses. Learning & memory (Cold Spring Harbor, N.Y.). vol 3. issue 2-3. 1999-09-09. PMID:10456081. |
the two forms of long-term potentiation (ltp) and one form of long-term depression (ltd) in hippocampal area ca1 are induced by different afferent tetani: ltd is induced by a 3- to 5-hz tetanus, whereas higher frequencies are necessary for ltp mediated by nmda receptors (25- to 50-hz tetanus) and ltp mediated by voltage-dependent calcium channels (200-hz tetanus). |
1999-09-09 |
2023-08-12 |
rat |