Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
M Korte, O Griesbeck, C Gravel, P Carroll, V Staiger, H Thoenen, T Bonhoeffe. Virus-mediated gene transfer into hippocampal CA1 region restores long-term potentiation in brain-derived neurotrophic factor mutant mice. Proceedings of the National Academy of Sciences of the United States of America. vol 93. issue 22. 1996-12-24. PMID:8901619. |
here we demonstrate that the re-expression of the bdnf gene in the ca1 region almost completely restores the severely impaired ltp in hippocampal slices of bdnf-deficient mice. |
1996-12-24 |
2023-08-12 |
mouse |
M Vreugdenhil, C Bruehl, R A Voskuyl, J X Kang, A Leaf, W J Wadma. Polyunsaturated fatty acids modulate sodium and calcium currents in CA1 neurons. Proceedings of the National Academy of Sciences of the United States of America. vol 93. issue 22. 1996-12-24. PMID:8901621. |
to establish whether pufas also regulate neuronal excitability, the effects of pufas on ina and ica were assessed in ca1 neurons freshly isolated from the rat hippocampus. |
1996-12-24 |
2023-08-12 |
rat |
K S Hsu, C C Huang, M T Su, J J Tsa. L-deprenyl (selegiline) decreases excitatory synaptic transmission in the rat hippocampus via a dopaminergic mechanism. The Journal of pharmacology and experimental therapeutics. vol 279. issue 2. 1996-12-24. PMID:8930179. |
these results indicate that the monoamine oxidase type b inhibitory ability leading to an increase of the dopaminergic tonus in the hippocampus is involved in the l-deprenyl-induced depression of excitatory synaptic transmission in the ca1 region of the rat hippocampus. |
1996-12-24 |
2023-08-12 |
rat |
K J Rhodes, M M Monaghan, N X Barrezueta, S Nawoschik, Z Bekele-Arcuri, M F Matos, K Nakahira, L E Schechter, J S Trimme. Voltage-gated K+ channel beta subunits: expression and distribution of Kv beta 1 and Kv beta 2 in adult rat brain. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 16. issue 16. 1996-12-13. PMID:8756417. |
in situ hybridization using crna probes revealed that these beta-subunit genes are heterogeneously expressed, with high densities of kv beta 1 mrna in the striatum, ca1 subfield of the hippocampus, and cerebellar purkinje cells, and high densities of kv beta 2 mrna in the cerebral cortex, cerebellum, and brainstem. |
1996-12-13 |
2023-08-12 |
rat |
N L Rempel-Clower, S M Zola, L R Squire, D G Amara. Three cases of enduring memory impairment after bilateral damage limited to the hippocampal formation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 16. issue 16. 1996-12-13. PMID:8756452. |
patient rb (human amnesia and the medial temporal region: enduring memory impairment following a bilateral lesion limited to field ca1 of the hippocampus, s. zola-morgan, l. r. squire, and d. g. amaral, 1986, j neurosci 6:2950-2967) was the first reported case of human amnesia in which detailed neuropsychological analyses and detailed postmortem neuropathological analyses demonstrated that damage limited to the hippocampal formation was sufficient to produce anterograde memory impairment. |
1996-12-13 |
2023-08-12 |
human |
J M Godfraind, E Reyniers, K De Boulle, R D'Hooge, P P De Deyn, C E Bakker, B A Oostra, R F Kooy, P J Willem. Long-term potentiation in the hippocampus of fragile X knockout mice. American journal of medical genetics. vol 64. issue 2. 1996-12-13. PMID:8844057. |
judged by field extracellular excitatory postsynaptic potential recordings in the ca1 hippocampal area, fmr1 knockout mice express ltp to a similar extent as their wild type littermates during the first 1-2 hr after high frequency stimulation. |
1996-12-13 |
2023-08-12 |
mouse |
G Rammes, D Swandulla, G L Collingridge, S Hartmann, C G Parson. Interactions of 2,3-benzodiazepines and cyclothiazide at AMPA receptors: patch clamp recordings in cultured neurones and area CA1 in hippocampal slices. British journal of pharmacology. vol 117. issue 6. 1996-12-11. PMID:8882618. |
interactions of 2,3-benzodiazepines and cyclothiazide at ampa receptors: patch clamp recordings in cultured neurones and area ca1 in hippocampal slices. |
1996-12-11 |
2023-08-12 |
Not clear |
G Rammes, D Swandulla, G L Collingridge, S Hartmann, C G Parson. Interactions of 2,3-benzodiazepines and cyclothiazide at AMPA receptors: patch clamp recordings in cultured neurones and area CA1 in hippocampal slices. British journal of pharmacology. vol 117. issue 6. 1996-12-11. PMID:8882618. |
gyki 52466 decreased the peak amplitude of hippocampal area ca1 ampa receptor-mediated excitatory postsynaptic currents (e.p.s.cs) (ic50 10.8 +/- 0.8 microm) with no apparent effect on response kinetics. |
1996-12-11 |
2023-08-12 |
Not clear |
G Rammes, D Swandulla, G L Collingridge, S Hartmann, C G Parson. Interactions of 2,3-benzodiazepines and cyclothiazide at AMPA receptors: patch clamp recordings in cultured neurones and area CA1 in hippocampal slices. British journal of pharmacology. vol 117. issue 6. 1996-12-11. PMID:8882618. |
the interactions of gyki 52466 and cyclothiazide on ampa receptor-mediated e.p.s.cs in area ca1 of hippocampal slices provide evidence that the decay time constant of these synaptic events are not governed by desensitization. |
1996-12-11 |
2023-08-12 |
Not clear |
A Rump, C Sommer, P Gass, S Bele, D Meissner, M Kiesslin. Editing of GluR2 RNA in the gerbil hippocampus after global cerebral ischemia. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 16. issue 6. 1996-12-11. PMID:8898712. |
postischemic delayed neuronal death (dnd) in ca1 of the gerbil hippocampus is thought to be caused by an abnormal increase of ca2+ influx into the cell, mediated by excessive activation of glutamate receptors. |
1996-12-11 |
2023-08-12 |
Not clear |
J O Malva, A P Carvalho, C M Carvalh. Domoic acid induces the release of glutamate in the rat hippocampal CA3 subregion. Neuroreport. vol 7. issue 7. 1996-12-10. PMID:8817560. |
also, in synaptosomes isolated from the ca3 sub-region of the hippocampus the domoic acid-induced release of glutamate was higher than that from the dentate gyrus (221.3%), from the ca1 (188.1%) or from the whole hippocampal synaptosomes (131.5%). |
1996-12-10 |
2023-08-12 |
rat |
E Elmér, P Alm, Z Kokaia, M Kokaia, B Larsson, M Keep, K E Andersson, O Lindval. Regulation of neuronal nitric oxide synthase mRNA levels in rat brain by seizure activity. Neuroreport. vol 7. issue 7. 1996-12-10. PMID:8817561. |
following 40 rapidly recurring seizures evoked by hippocampal stimulations, nos mrna expression decreased by 56% in the dentate granule cell layer (maximum at 2 h) and increased by 420,105 and 1260% in the ca1 and ca3 pyramidal layers and piriform cortex, respectively (maximum at 12-24 h). |
1996-12-10 |
2023-08-12 |
rat |
Z T Zhu, X X Zhang, J Liu, G Z Ji. Effect of desipramine on spontaneous activity of hippocampal CA1 neuron after transient cerebral ischemia in rats. Zhongguo yao li xue bao = Acta pharmacologica Sinica. vol 17. issue 1. 1996-12-05. PMID:8737449. |
to study the spontaneous firing of ca1 neurons in rat hippocampus after transient cerebral ischemia and the effect of desipramine (des) on the post-ischemic electric activity of ca1 neurons. |
1996-12-05 |
2023-08-12 |
rat |
Y Izumi, A M Benz, D B Clifford, C F Zorumsk. Nitric oxide inhibitors attenuate ischemic degeneration in the CA1 region of rat hippocampal slices. Neuroscience letters. vol 210. issue 3. 1996-12-05. PMID:8805119. |
nitric oxide inhibitors attenuate ischemic degeneration in the ca1 region of rat hippocampal slices. |
1996-12-05 |
2023-08-12 |
rat |
J Wu, G Z Ji. Tetrahydroberberine suppresses dopamine-induced potassium current in acutely dissociated CA1 pyramidal neurons from rat hippocampus. Neuroscience letters. vol 207. issue 3. 1996-12-04. PMID:8728473. |
effects of tetrahydroberberine (thb) on dopamine (da)-induced response have been investigated in single pyramidal neurons freshly dissociated from ca1 area of the hippocampus using the nystatin perforated patch-clamp, whole-cell recording technique under voltage-clamp configuration. |
1996-12-04 |
2023-08-12 |
rat |
A Fletcher, E A Forster, D J Bill, G Brown, I A Cliffe, J E Hartley, D E Jones, A McLenachan, K J Stanhope, D J Critchley, K J Childs, V C Middlefell, L Lanfumey, R Corradetti, A M Laporte, H Gozlan, M Hamon, C T Douris. Electrophysiological, biochemical, neurohormonal and behavioural studies with WAY-100635, a potent, selective and silent 5-HT1A receptor antagonist. Behavioural brain research. vol 73. issue 1-2. 1996-12-04. PMID:8788530. |
in vitro electrophysiological studies demonstrated that way-100635 had no 5-ht1a receptor agonist actions, but dose-dependently blocked the effects of agonists at both the postsynaptic 5-ht1a receptor in the ca1 region of the hippocampus, and the somatodendritic 5-ht1a receptor located on dorsal raphe 5-ht neurones. |
1996-12-04 |
2023-08-12 |
mouse |
S M Fitzjohn, A J Irving, M J Palmer, J Harvey, D Lodge, G L Collingridg. Activation of group I mGluRs potentiates NMDA responses in rat hippocampal slices. Neuroscience letters. vol 203. issue 3. 1996-12-03. PMID:8742030. |
the pharmacology of the metabotropic glutamate receptor (mglur)-mediated potentiation of n-methyl-d-aspartate (nmda)-evoked depolarisations in the ca1 region of rat hippocampal slices was investigated using an extracellular grease-gap method. |
1996-12-03 |
2023-08-12 |
rat |
H Schwegler, M Boldyreva, M Pyrlik-Göhlmann, R Linke, J Wu, K Zille. Genetic variation in the morphology of the septo-hippocampal cholinergic and GABAergic system in mice. I. Cholinergic and GABAergic markers. Hippocampus. vol 6. issue 2. 1996-12-03. PMID:8797015. |
we found significant strain differences for the number of chat-positive neurons in the ms/vdb; in the numbers of cholinergic septo-hippocampal projection neurons; in the density of cholinergic fibers in hippocampal subfields ca3c, ca1, and in the dentate gyrus; and in the density of muscarinic receptors in the hippocampus. |
1996-12-03 |
2023-08-12 |
mouse |
J Mitchell, M Gatherer, N Best, L Sundstrom, H V Whea. Hippocampal NPY neurons project to the fascia dentata in organotypic cultures. Hippocampus. vol 6. issue 2. 1996-12-03. PMID:8797017. |
in addition to the known npy-ir neurons in the hippocampus proper and in the hilus of the fascia dentata, isolated, large, multipolar, npy-ir neurons were observed in the subiculum and in areas ca1 and ca3. |
1996-12-03 |
2023-08-12 |
rat |
S E Krahl, L M Treas, R F Berma. Effects of in vivo perforant path kindling on 0-Mg(2+)-induced CA1 burst activity in rat hippocampal slices. Brain research. vol 723. issue 1-2. 1996-12-03. PMID:8813398. |
the present study examined the effects of perforant path kindling on 0-mg(2+)-induced epileptiform bursting in the ca1 region of hippocampal slices. |
1996-12-03 |
2023-08-12 |
rat |