| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Ylinen, H Lahtinen, J Sirviö, J Partanen, A Asikainen, A Gulyas, T F Freund, P Riekkine. Behavioural, electrophysiological and histopathological changes following sustained stimulation of the perforant pathway input to the hippocampus: effect of the NMDA receptor antagonist, CGP 39551. Brain research. vol 553. issue 2. 1991-12-13. PMID:1681982. |
these results indicate that the impairment of spatial learning/memory seems to be dependent not only on the degree of cell degeneration in the ca1 subfield of the hippocampus but also on the frequency of interictal spikes, at least in this model of epilepsy. |
1991-12-13 |
2023-08-11 |
human |
| H Benvenist. The excitotoxin hypothesis in relation to cerebral ischemia. Cerebrovascular and brain metabolism reviews. vol 3. issue 3. 1991-12-13. PMID:1931486. |
the purpose of this work was (a) to measure extracellular glutamate concentration increases during ischemia in a selective vulnerable brain region (rat ca1 hippocampus), (b) to evaluate the toxicity of such a concentration increase, and (c) to investigate the relationship between ischemia-induced glutamate accumulation and changes of calcium homeostasis. |
1991-12-13 |
2023-08-11 |
rat |
| S M Strain, R A Taske. Hippocampal damage produced by systemic injections of domoic acid in mice. Neuroscience. vol 44. issue 2. 1991-12-05. PMID:1944890. |
with both toxins the most extensive damage was always observed in the ca3 region of the hippocampus, with lesser degrees of damage observed in other hippocampal regions (ca4 greater than ca1 greater than ca2 greater than dentate granule cells). |
1991-12-05 |
2023-08-11 |
mouse |
| A Valjakka, K Lukkarinen, E Koivisto, P Riekkinen, R Miettinen, M M Airaksinen, R Lammintausta, P Riekkine. Modulation of EEG rhythmicity and spike activity in the rat hippocampus by systemically administered tetrahydroaminoacridine, scopolamine and atipamezole. Brain research bulletin. vol 26. issue 5. 1991-12-04. PMID:1682015. |
the hippocampal eeg recording electrodes were implanted bilaterally in the hilus of the dentate gyrus (dg) and the stratum radiatum layer of the ca1 area in young (2-3-month-old) and aged (17-20-month-old) rats. |
1991-12-04 |
2023-08-11 |
human |
| F F Johansen, N H Dieme. Enhancement of GABA neurotransmission after cerebral ischemia in the rat reduces loss of hippocampal CA1 pyramidal cells. Acta neurologica Scandinavica. vol 84. issue 1. 1991-11-21. PMID:1656687. |
we conclude that enhancement of postischemic gaba neurotransmission, during the first 2-3 days after ischemia, may reduce the ischemic ca1 damage through a continuous increase in hippocampal gaba extracellular levels (no-328), or through an increase in sensitivity to gaba neurotransmission (diazepam). |
1991-11-21 |
2023-08-11 |
rat |
| B E Mileson, R D Schwart. The use of locomotor activity as a behavioral screen for neuronal damage following transient forebrain ischemia in gerbils. Neuroscience letters. vol 128. issue 1. 1991-11-05. PMID:1922950. |
the extensive pyramidal cell damage in the ca1 region of the hippocampus in bco gerbils was associated with the significant increase in locomotor activity. |
1991-11-05 |
2023-08-11 |
Not clear |
| J A van Eekelen, M C Bohn, E R de Kloe. Postnatal ontogeny of mineralocorticoid and glucocorticoid receptor gene expression in regions of the rat tel- and diencephalon. Brain research. Developmental brain research. vol 61. issue 1. 1991-11-04. PMID:1655309. |
at pnd 2, abundant radiolabelled gr mrna was found widespread over the tel- and diencephalon, with the highest density observed in cell field ca1 and ca2 of the hippocampus and the parvocellular division of the hypothalamic paraventricular nucleus. |
1991-11-04 |
2023-08-11 |
rat |
| G Bagetta, M T Corasaniti, G Nisticó, N G Bower. High vulnerability of dentate granule cells to the neuropathological effects induced by intrahippocampal injection of tetanus toxin. Neuropharmacology. vol 30. issue 7. 1991-11-04. PMID:1922689. |
ca1 and ca3 pyramidal cell layers) of the hippocampus. |
1991-11-04 |
2023-08-11 |
mouse |
| M L Proietti, A Scotti de Carolis, C Frank, Y C Zeng, S Sagratell. In vitro depressant effects of U-54494A, an anticonvulsant related to kappa opioids, in the hippocampus. Neuropharmacology. vol 30. issue 6. 1991-10-31. PMID:1656303. |
the results demonstrate: (1) the inability of u-54494a to show antagonistic activity in two in vitro models of interictal epilepsy; (2) a depressant effect of u-54494a on basal synaptic transmission in the ca1 region of the hippocampus, which may be related to an influence on transneuronal calcium currents and which may be involved in the reported antagonism of ictal epileptic seizures by drugs. |
1991-10-31 |
2023-08-11 |
rat |
| K R Magnusson, J F Koerner, A A Larson, D H Smullin, S R Skilling, A J Beit. NMDA-, kainate- and quisqualate-stimulated release of taurine from electrophysiologically monitored rat hippocampal slices. Brain research. vol 549. issue 1. 1991-10-24. PMID:1893243. |
to determine whether taurine is released as a neurotransmitter by non-toxic concentrations of eaas, or exclusively as a neuroprotectant in response to excitotoxicity, we monitored the release of amino acids from hippocampal slices during simultaneous electrophysiological recording in the ca1 region to assess tissue viability. |
1991-10-24 |
2023-08-11 |
rat |
| P Van den Hooff, M Galva. Electrophysiology of the 5-HT1A ligand MDL 73005EF in the rat hippocampal slice. European journal of pharmacology. vol 196. issue 3. 1991-10-24. PMID:1893914. |
the actions of 5-hydroxytryptamine (5-ht) and the 5-ht1a receptor ligand mdl 73005ef on neuronal activity in the ca1 region of rat hippocampal slices in vitro were recorded using intra- and extracellular recording techniques. |
1991-10-24 |
2023-08-11 |
rat |
| M Andreasen, J D Lamber. Noradrenaline receptors participate in the regulation of GABAergic inhibition in area CA1 of the rat hippocampus. The Journal of physiology. vol 439. 1991-10-22. PMID:1680188. |
noradrenaline receptors participate in the regulation of gabaergic inhibition in area ca1 of the rat hippocampus. |
1991-10-22 |
2023-08-11 |
rat |
| M A Whittington, H J Littl. A calcium channel antagonist stereoselectively decreases ethanol withdrawal hyperexcitability but not that due to bicuculline, in hippocampal slices. British journal of pharmacology. vol 103. issue 2. 1991-10-07. PMID:1832063. |
extracellular recordings were made from ca1 area of isolated hippocampal slices of the mouse after chronic ethanol administration in vivo, with orthodromic stimulation of the schaffer collateral/commissural fibres. |
1991-10-07 |
2023-08-11 |
mouse |
| M Joëls, G Bouma, W Hesen, Y Zeger. Increased effect of noradrenaline on synaptic responses in rat CA1 hippocampal area after adrenalectomy. Brain research. vol 550. issue 2. 1991-10-07. PMID:1884244. |
increased effect of noradrenaline on synaptic responses in rat ca1 hippocampal area after adrenalectomy. |
1991-10-07 |
2023-08-11 |
rat |
| A Cintra, V Solfrini, L F Agnati, J A Gustafsson, K Fux. Strongly glucocorticoid receptor immunoreactive neurons in the neonatal rat brain. Neuroreport. vol 2. issue 2. 1991-10-04. PMID:1883989. |
moderately to strongly gr ir neurons were found in the locus coeruleus and raphe nuclei, while only weakly gr ir neurons were present in the ca1 and ca2 areas of the hippocampus. |
1991-10-04 |
2023-08-11 |
rat |
| P K Stanton, S Chattarji, T J Sejnowsk. 2-Amino-3-phosphonopropionic acid, an inhibitor of glutamate-stimulated phosphoinositide turnover, blocks induction of homosynaptic long-term depression, but not potentiation, in rat hippocampus. Neuroscience letters. vol 127. issue 1. 1991-09-30. PMID:1679224. |
recently, we have reported an associative long-term depression (ltd) of synaptic strength in hippocampal field ca1 that is produced when a low-frequency test input is negatively correlated in time with a high-frequency conditioning input. |
1991-09-30 |
2023-08-11 |
rat |
| P K Stanton, S Chattarji, T J Sejnowsk. 2-Amino-3-phosphonopropionic acid, an inhibitor of glutamate-stimulated phosphoinositide turnover, blocks induction of homosynaptic long-term depression, but not potentiation, in rat hippocampus. Neuroscience letters. vol 127. issue 1. 1991-09-30. PMID:1679224. |
we have also found that pairing of synaptic activity with postsynaptic hyperpolarization is sufficient to induce ltd. we report here that 2-amino-3-phosphonopropionate (ap3), a selective inhibitor of phosphoinositide (pi) turnover mediated by the metabotropic glutamate receptor, blocks the induction of associative ltd in hippocampal field ca1, but does not impair the induction of ltp. |
1991-09-30 |
2023-08-11 |
rat |
| D Leifer, D G Cole, N W Kowal. Neuropathologic asymmetries in the brain of a patient with a unilateral status epilepticus. Journal of the neurological sciences. vol 103. issue 2. 1991-09-30. PMID:1715386. |
autopsy study of a patient who died after an episode of prolonged unilateral status epilepticus revealed neuronal loss in the hippocampus on the epileptic side, with gliosis confined to the ca1 and ca3 fields. |
1991-09-30 |
2023-08-11 |
human |
| N Agopyan, I Agopya. Effects of protein kinase C activators and inhibitors on membrane properties, synaptic responses, and cholinergic actions in CA1 subfield of rat hippocampus in situ and in vitro. Synapse (New York, N.Y.). vol 7. issue 3. 1991-09-27. PMID:1882329. |
effects of protein kinase c activators and inhibitors on membrane properties, synaptic responses, and cholinergic actions in ca1 subfield of rat hippocampus in situ and in vitro. |
1991-09-27 |
2023-08-11 |
rat |
| H J Gertz, H Krüger, S Patt, J Cervos-Navarr. Tangle-bearing neurons show more extensive dendritic trees than tangle-free neurons in area CA1 of the hippocampus in Alzheimer's disease. Brain research. vol 548. issue 1-2. 1991-09-19. PMID:1714332. |
tangle-bearing neurons show more extensive dendritic trees than tangle-free neurons in area ca1 of the hippocampus in alzheimer's disease. |
1991-09-19 |
2023-08-11 |
Not clear |